Side effects might include dizziness, dry mouth, and blurred vision—not exactly a great trade-off for a slimmer figure. This drug’s primary superpower is reducing muscle spasms in the intestines, not trimming waistlines. Pancreatitis (swelling of the pancreas) may occur while you are using this medicine. This medicine may increase the risk of having thyroid tumors. In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. Doctors regularly administer Dicyclo-mine through controlled dosing procedures which aim to reduce adverse effects and maximize the treatment’s results. Medical professionals advise various dicyclo-mine treatment options, including injectable dosage forms and tablets and capsules. Dicyclomine is given to patients as a prescription medication to treat intestinal cramps brought on by irritable bowel syndrome (IBS) and other illnesses. But you may need a lower dose if you experience side effects. But Mounjaro was approved by the FDA in 2022 to treat Type 2 diabetes, while Zepbound is approved for weight loss and sleep apnea. Zepbound is a once-weekly, injectable medication that has the same active ingredient as the Type 2 diabetes treatment Mounjaro (tirzepatide). In fact, 15 million adults in the U.S. may be taking weight-loss medication by 2030, according to Goldman Sachs research. People who take Zepbound may find that, over time, their weight loss stops or plateaus. Eli Lilly recommends that people taking Zepbound start with the lowest dosage and work with their healthcare professionals to gradually increase it if needed. But it’s important to note that your medication could be dropped anytime during the coverage year. About a third of people taking the highest dose lost up to 25% of their initial body weight, or more than 58 lbs, according to an Eli Lilly news release about the initial FDA approval. Excess weight can lead to a higher risk of many serious health conditions, including hypertension (high blood pressure), Type 2 diabetes, and sleep apnea. Zepbound may result in greater weight loss and has proven benefits for obstructive sleep apnea. And a comparison study found a similar occurrence of serious side effects in people using Zepbound and Wegovy. They share similar potential side effects, including nausea, vomiting, and diarrhea. Zepbound and Wegovy are both FDA approved for weight loss. This helps spot any potential risks or side effects. They’ll also go through a questionnaire to get all the nitty-gritty details of your health. First off, they’ll check your medical history. Don’t fall for the myths; stick to the facts and always get proper medical advice. Note- you need to know about this medicine diclofenac-potassium-serratiopeptidase Before using the medication a person should check with their doctor if they have glaucoma or heart problems. The recommended amount of this medication is essential since excessive usage can cause dry mouth and dizziness in addition to blurred vision and constipation. After swallowing the medication it starts to work between one to two hours for reducing gastrointestinal discomfort. Dicyclomine also isn’t recommended for adults age 65 and older because the side effects are riskier for this age group.While Bentyl has been FDA-approved since 1950 and has proven very effective and safe in clinical trials, like all medications, it comes with the possibility of side effects.And a comparison study found a similar occurrence of serious side effects in people using Zepbound and Wegovy.Yes, it’s crucial to speak with your healthcare provider before starting dicyclomine for any purpose.This medicine may be less effective in black patients.You can take it in liquid form on an empty stomach, or you can visit the doctor's office every so often for an injectable version of the drug, per the FDA. If your symptoms do not improve or if they become worse, check with your doctor. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The amount of medicine that you take depends on the strength of the medicine. If your dose is different, do not change it unless your doctor tells you to do so. It is best to take this medicine on an empty stomach. WikiDoc is not a professional health care provider, nor is it a suitable replacement for a licensed healthcare provider. We want to make healthcare easier and transparent. If symptoms occur, the drug should be discontinued and a physician contacted. Make sure you know how you react to the medicine before you drive, use machines, or do other things that could be dangerous if you are dizzy or not alert. Anaphylaxis can be life-threatening and requires immediate medical attention. Using this medicine while you are pregnant can harm your unborn baby. Blood tests may be needed to check for unwanted effects. Rather than relying on unapproved uses of medications, evidence-based weight loss strategies have demonstrated consistent, reproducible results across thousands of studies. In the case of dicyclomine for weight loss, the minimal evidence of benefit combined with documented side effect risks makes this an unfavorable trade-off from a medical perspective. The weight loss discussions surrounding dicyclomine often appear in online forums and social media rather than in peer-reviewed medical literature. In recent years, some individuals have explored whether dicyclomine 10 mg might support weight loss efforts, particularly due to its effects on digestive function and appetite. When she is not seeing patients, Dr. Scott works with neighboring health departments to promote public health, especially to communities that have been historically underserved. Dr. Scott enjoys connecting with her patients, empowering them to understand and take ownership of their health, and encouraging them to ask questions so that they can make informed and thoughtful decisions. Diagnosed with celiac disease during medical school, she realized the power of improving one's health through diet and lifestyle habits, which she later incorporated into her practice. Allison Buttarazzi, MD, is board-certified in internal medicine and lifestyle medicine, and is a certified health and well-being coach. She is an American Council on Exercise–certified health coach, group fitness instructor, senior fitness specialist, and weight management specialist. Dicyclomine is in a class of medications called anticholinergics. They can guide you on safe usage and potential interactions with other medications. Eventually, integrating dicyclomine into a broader approach that includes healthy eating and exercise could yield better results than relying on it alone. While it may help reduce cravings and improve overall eating experiences, it’s essential to remain cautious about its side effects. Zepbound is a long-term option for managing body weight that was FDA approved for adult use in 2023. That may be why, according to a 2022 Gallup poll from 2017 to 2021, more than half of U.S. adults expressed a desire to lose weight. Once-weekly semaglutide in adults with overweight or obesity. FDA approves first medication for obstructive sleep apnea. Tirzepatide for the treatment of obstructive sleep apnea and obesity. Dicyclomine should be used with caution in patients with known or suspected prostatic enlargement, in whom prostatic enlargement may lead to urinary retention see ADVERSE REACTIONS (6.3).Usually, adults are prescribed mg three to four times daily.After swallowing the medication it starts to work between one to two hours for reducing gastrointestinal discomfort.Also, carry an ID card in your wallet or purse that says that you have diabetes and a list of all of your medicines.She also teaches medical trainees and lectures medical students at the Emory University School of Medicine.Dicyclomine is an antispasmodic and anticholinergic agent that is FDA approved for the treatment of functional bowel disorder or irritable bowel syndrome. There are various medications used to treat gastrointestinal spasms. If an overdose occurs, seek medical attention immediately. It’s important to follow your healthcare provider’s instructions carefully. While dicyclomine is generally safe for most people, it is not suitable for everyone. To minimize side effects like dry mouth, stay hydrated by drinking plenty of water throughout the day. So, you’re thinking about using dicyclomine 10 mg for weight loss?In three of the infants who died following administration of dicyclomine hydrochloride see WARNINGS AND PRECAUTIONS (5.1), the blood concentrations of drug were 200 ng/mL, 220 ng/mL, and 505 ng/mL.If you’ve been considering dicyclomine for weight loss, the appropriate step is to discuss your weight management goals with your primary care physician or a specialist in obesity medicine.Anticholinergics antagonize the effects of antiglaucoma agents.Dicyclomine is known to cause several side effects, and it isn’t a safe medication for everyone.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.As mentioned, dicyclomine doesn’t last long in your body.Contact your primary care provider or prescriber if you're too tired to the point where it's affecting your ability to go about your day.As with all medications, it's a good idea to see how Bentyl affects you before you get behind the wheel of a car and carry on with your day. Regular check-ins with a healthcare provider allow for personalized adjustments. Long-term studies show that consistent use at starting doses prevents rebound weight gain. Hydration and regular movement, like walking 30 minutes daily, amplify the medication’s effects. In three of the infants who died following administration of dicyclomine hydrochloride (see WARNINGS), the blood concentrations of drug were 200, 220, and 505 ng/mL, respectively.Imagine your intestines doing the cha-cha all day long.If you forget to take a dose, take it as soon as you remember, unless it is nearly time for your next dose.The information provided in this blog is for educational purposes only and is not a substitute for professional medical advice.Drug hypersensitivity including face edema, angioedema, anaphylactic shock, dermatitis allergic, erythema, rashWho knew that a drug meant to tackle tummy troubles could also help with those stubborn love handles?Thinking about dicyclomine for weight loss? In this instance, treatment with this drug would be inappropriate and possibly harmful. In these trials, most of the side effects were typically anticholinergic in nature (see table) and were reported by 61% of the patients. Medical supervision is necessary for patients who take Dicyclo-mine and they must follow their prescribed dose amounts. Breastfeeding mothers need to exercise care about using Dicyclo-mine since the medication passes through breast milk which affects the health of their nursing infant. Expectant mothers need to receive medical approval before starting Dicyclo-mine because the drug crosses into the placenta. One of the biggest pros I’ve noticed is that dicyclomine can help ease digestive discomfort. Let’s jump into what makes this medication stand out when it comes to shedding those pesky pounds. But hey, sometimes the best helpers come in unexpected packages. Some might find dicyclomine makes them feel queasy instead of svelte! Certain medications and substances can interact with dicyclomine, causing harm.Sometimes, small tweaks yield big results without higher doses.This is not a complete list of possible side effects.Because the medications contain different active ingredients, some people may tolerate one better than the other.For more immediate effects, particularly in a clinical setting, dicyclomine can be administered via injection.Instead of relying on dicyclomine 10 mg for weight loss, consider proven methods. Drug interactions may change how your medications work or increase your risk for serious side effects. Many people using this medication do not have serious side effects. To reduce your risk of side effects, your doctor may direct you to start this medication at a low dose and gradually increase your dose. Take this medication by mouth with or without food as directed by your doctor, usually 4 times a day. "It does not cure the condition — rather, it manages the symptoms. Individual responses to dicyclomine (and to IBS treatments more broadly) can vary greatly," she adds. All medications come with a warning of serious side effects that only happen on the rare occasion. As with many medications, there are particular negative drug interactions that you need to watch out for. They may be able to adjust your dose or prescribe you a different medication that does not cause these adverse effects. As with all medications, it's a good idea to see how Bentyl affects you before you get behind the wheel of a car and carry on with your day. The medication relaxes the muscles in the stomach and intestines, which helps slow down gut movement. Yes, dicyclomine should help with diarrhea that's caused by irritable bowel syndrome (IBS). Don't take antacids, though, because they can affect how well dicyclomine works for you. But we need more research done to know whether this medication is beneficial if you have both GERD and IBS. Talk to your gastroenterologist or primary care provider if you're concerned with how well dicyclomine is working for you. Physical activity complements the treatment by burning calories and building muscle. Pairing Zepbound with healthy habits maximizes its potential at 2.5 mg. Staying active can also alleviate some symptoms by promoting better digestion. Some believe this effect might reduce appetite or bloating, indirectly supporting weight loss efforts. Dicyclomine 20 mg is a prescription medication commonly used to relieve stomach cramps and symptoms of IBS. Dicyclomine is known to cause several side effects, and it isn’t a safe medication for everyone. So you’ll need to take it 4 times a day for ongoing relief. If you’re having trouble remembering to take dicyclomine throughout the day, or the dosing schedule isn’t convenient for you, talk to your prescriber. After 1 week, your healthcare provider may raise your dose to 40 mg four times a day (160 mg daily). Your healthcare provider may have you take a different dose based on how well the medication works for you and what side effects you experience. The data described below reflect exposure in controlled clinical trials involving over 100 patients treated for functional bowel/irritable bowel syndrome with dicyclomine hydrochloride at initial doses of 160 mg daily (40 mg 4 times a day). Clinical data suggests 5-10% body weight reduction over time, but initial results are gradual. Ultimately, success depends on individual commitment and medical guidance for long-term health improvements. Zepbound at 2.5 mg offers a viable starting point for weight loss, with potential for modest reductions when paired with diet and exercise. Sustaining weight loss requires ongoing commitment. Tests for mydriatic effects in mice showed that dicyclomine was approximately 1/500 as potent as atropine; antisialagogue tests in rabbits showed dicyclomine to be 1/300 as potent as atropine. In three of the infants who died following administration of dicyclomine hydrochloride see WARNINGS AND PRECAUTIONS (5.1), the blood concentrations of drug were 200 ng/mL, 220 ng/mL, and 505 ng/mL. Dicyclomine drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function. If efficacy is not achieved within 2 weeks or side effects require doses below 80 mg per day, the drug should be discontinued. When you are taking any of these medicines, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Additionally, dicyclomine can have the opposite effects as metoclopramide (Reglan) and glaucoma medications. You shouldn't take other anticholinergic medications with dicyclomine; otherwise, your risk for side effects is greater. There are a few medications that you might want to avoid taking with dicyclomine because of drug interactions. As a result, it slows down or stops involuntary muscle spasms within the body (including the intestines, which are often overactive in people with IBS). If you have irritable bowel syndrome (or IBS) and lifestyle changes alone are not relieving your symptoms, your doctor may prescribe the medication Bentyl. Learn the facts about irritable bowel syndrome, including its symptoms and causes. Johnsen is passionate about empowering patients with evidence-based tools to achieve sustainable health and long-term well-being. He is board-certified in internal medicine by the American Board of Internal Medicine and is a diplomate of the National Certification Commission for Acupuncture and Oriental Medicine.He received a bachelor's degree in neuroscience from Brown University, where he also earned his medical degree. Instead of relying on dicyclomine 10 mg for weight loss, consider proven methods. Similarly, dicyclomine 20 mg used for IBS or spasms doesn’t target weight loss. Some wonder if dicyclomine used for anxiety could indirectly help with weight loss, as stress can lead to overeating. Check with your doctor to ensure dicyclomine is safe with your current medications. Certain medications and substances can interact with dicyclomine, causing harm. One study found that overweight individuals who took dicyclomine for six weeks lost an average of 4.4 pounds, while those who took a placebo lost only 2.2 pounds.And people who stop taking weight-loss medications typically regain much, but not all, of the weight they lost.Note- you need to know about this medicine diclofenac-potassium-serratiopeptidaseBy blocking acetylcholine, dicyclomine relaxes the muscles in the stomach and intestines to lessen cramping in people with IBS.However, Wegovy’s manufacturer is seeking approval of a 7.2 mg injection dose, which is 3 times higher than the current highest available dose.Some people may turn to online sources for GLP-1s like Wegovy and Zepbound.Using dicyclomine 20 mg for weight loss isn’t FDA-approved, and its side effects may outweigh benefits for non-IBS users."Not everyone taking Bentyl will experience reduced sweating, though. Some people might not notice this side effect at all," she adds. It is important that your doctor check your progress while using this medicine to make sure this medicine is working properly and to check for unwanted effects. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If you miss a dose of this medicine, take it as soon as possible. If you have insurance, review your plan’s summary of benefits and coverage and formulary (list of covered medications) to determine whether Zepbound is covered. The 2.5 mg dose is often less costly because it’s a starter dose and the other 5 doses are maintenance doses. This means that, without insurance or manufacturer discounts, the medication can cost more than $14,000 annually because the 28-day supply means you’ll need 13 fills in a year. Make sure to weigh the risks and benefits with your healthcare provider. That’s the good, the bad, and the ugly of dicyclomine side effects. Though rare, if you experience hallucinations or severe confusion, you should contact a healthcare provider immediately. Some side effects of dicyclomine are a bit scarier. Some users report feeling slimmer due to less bloating, while others see no weight change. Generic dicyclomine remains widely available. While it doesn’t treat anxiety directly, reducing IBS symptoms like bloating may ease stress for some users. Health In three of the infants who died following administration of dicyclomine hydrochloride (see WARNINGS), the blood concentrations of drug were 200, 220, and 505 ng/mL, respectively. Abuse of and/or dependence on dicyclomine for anticholinergic effects have been rarely reported. Controlled clinical trials have provided frequency information for reported adverse effects of dicyclomine hydrochloride listed in a decreasing order of frequency. This drug is known to be substantially excreted by the kidney, and the risk of toxic reactions to this drug may be greater in patients with impaired renal function. What should you not take with dicyclomine? More serious side effects, though rare, can include confusion or rapid heartbeat. However, this is often temporary water weight, not fat loss. Some users report feeling less bloated, which might make them think they’ve lost weight. She became board-certified in lifestyle medicine in 2021 and further expanded her expertise by earning board certification in obesity medicine in 2025. Deeply interested in the impact of lifestyle on both physical and mental health, Johnsen transitioned her focus toward prevention-based care after witnessing how many chronic conditions could be avoided or improved through lifestyle interventions. She completed her internal medicine internship at the University of Nevada and her residency at a Stanford-affiliated program in Santa Clara, California. Dr. Johnsen began her medical career as an ob-gyn in Russia before relocating to the United States in 2000. It's recommended to avoid or limit alcohol while you're taking dicyclomine. Contact your primary care provider or prescriber if you're too tired to the point where it's affecting your ability to go about your day. Yes, it's possible for dicyclomine to make you sleepy. There might be other options to help relieve these symptoms. Patients with kidney or liver issues should exercise caution while taking this medicine. Patients who have kidney or liver problems should exercise caution when taking this medicine. Seek medical help right away if you have any allergic reactions. If you're allergic to this medicine, don't take it. There is limited information regarding Dicyclomine Look-Alike Drug Names in the drug label. This gradual approach ensures safety and efficacy, making it suitable for long-term use in managing weight. The medication is administered once a week via a subcutaneous injection, usually in the abdomen, thigh, or upper arm. For those beginning at 2.5 mg, the focus is often on building tolerance before increasing the dose. With rising interest in GLP-1 receptor agonists like Zepbound, it’s important to look at the science behind it. We simplify medical science so you can make decisions with clarity and confidence, not confusion. The drug produces more intense side effects in elderly patients and children. The medication prevents acetylcholine inhibition which enables the treatment of IBS symptoms through reduced cramping and spasming activity. A patient receiving dicyclomine medication will experience gastric tract muscle spasm relief through antispasmodic drug properties. Your healthcare provider will work with you to determine the best Bentyl dosage for your IBS symptoms. If you’re consistently missing doses of Bentyl, speak with your healthcare provider. It should not be given to patients with myasthenia gravis except to reduce adverse muscarinic effects of an anticholinesterase see CONTRAINDICATIONS (4). These CNS signs and symptoms usually resolve within 12 to 24 hours after discontinuation of the drug. Psychosis and delirium have been reported in sensitive individuals (such as elderly patients and/or in patients with mental illness) given anticholinergic drugs. If symptoms occur, the drug should be discontinued and supportive measures instituted. The peripheral effects of dicyclomine hydrochloride are a consequence of their inhibitory effect on muscarinic receptors of the autonomic nervous system. Keep reading to find the answer to these and other commonly asked questions about dicyclomine. And is dicyclomine used for anxiety or other conditions not related to IBS? It is a short-term aid with lifestyle changes such as a healthy diet and exercise. How does stress relate to gastrointestinal issues when using dicyclomine? The data reflects health insurance coverage as of August 2025. We obtained national prescription coverage data for each medication from Managed Markets Insight & Technology (MMIT). If this medication isn’t covered by your insurance, you can ask your prescription plan administrator for an exception by filing an appeal. For as little as $25, you can get a 28-day supply of 4 prefilled pens or an 84-day supply of 12 prefilled pens of Zepbound if you have commercial insurance. Some studies have shown that combining the 10 mg and 20 mg forms of Dicyclomine can be more effective in causing weight loss than using either form alone. While it is not as effective as the 10 mg form in causing weight loss, it can still be used as part of a comprehensive weight loss plan. In contrast, the 20 mg form of Dicyclomine has been used to help individuals with IBS manage their symptoms, including bloating and abdominal pain. The following side effects may get better over time as your body gets used to the medication. In summary, despite antispasmodics as a class having been shown to be more effective than placebo in the treatment of GI conditions such as IBS, recent evidence comparing the efficacy and safety of dicyclomine versus placebo or other antispasmodic drugs for GI conditions are lacking. The RCT by Page et al. was the sole study on dicyclomine identified in a 2012 systematic review and meta-analysis of the effects of antispasmodic agents as compared to placebo in the treatment of IBS. She received a bachelor's degree in biology and a master's of public health in nutrition from Tulane University. Laura J. Martin, MD, MPH, is a board-certified internal medicine and palliative care physician practicing at City of Hope in Atlanta. He is board certified in internal medicine, cardiovascular disease, and clinical cardiac electrophysiology through the American Board of Internal Medicine. Following residency and fellowship, Cutler accepted a position as an assistant professor of medicine at the MetroHealth Campus of Case Western Reserve University until he joined his current partners at Intermountain Heart Rhythm Specialists. After medical school, Cutler entered the highly selective ABIM Research Pathway physician-scientist training program at the MetroHealth Campus of Case Western Reserve University in Cleveland. Why It’s Effective: It’s vital to start with the lower dose to gauge how well the person tolerates it, gradually increasing if necessary. Usually, adults are prescribed mg three to four times daily. The typical dosage for dicyclomine 10 mg is usually tailored to the individual’s needs. Here’s a breakdown of the recommended dosage and best methods to take this medication. For optimal results and safety, understanding the dosage guidelines and administration for dicyclomine 10 mg is essential. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Clinical studies of dicyclomine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Safety and effectiveness in pediatric patients have not been established. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Being open with your healthcare provider is key. Prescribing medications for uses other than their intended purpose can be quite risky. Here are some crucial considerations about drug interactions and health conditions you should know. Dicyclomine 10 mg can interact with other medications and may not be suitable for everyone. Jane Yoon Scott, MD, is an infectious disease physician and an assistant professor of medicine at Emory University in Atlanta. She has served on various boards for organizations that focus on health equity, decreasing implicit bias, addressing social determinants of health, and empowering communities to advocate for their health. Young Moss is the creator of the websites DrStephanieYoMo.com and MenopauseInColor.com, providing practical health and wellness tips and resources for women experiencing perimenopause and menopause. She uses her platform to educate families on ways to decrease and eliminate health disparities by incorporating wellness and mental health techniques. Dr. Young Moss is the owner of Integrative Pharmacy Outcomes and Consulting, which focuses on educating underserved communities on ways to reduce and prevent health disparities. Evidence-Based Weight Loss Approaches FDA approves Lilly’s Mounjaro (tirzepatide) injection, the first and only GIP and GLP-1 receptor agonist for the treatment of adults with type 2 diabetes. You won’t lose weight on Ozempic forever. GoodRx Health has strict sourcing policies and relies on primary sources such as medical organizations, governmental agencies, academic institutions, and peer-reviewed scientific journals. But if it’s close to the time of your next dose, skip the missed dose. If your healthcare provider has mentioned Bentyl as a treatment option, you may be wondering how you’ll take it. In vivo studies in cats and dogs showed dicyclomine to be equally potent against acetylcholine (ACh)- or barium chloride (BaCl2)-induced intestinal spasm while atropine was at least 200 times more potent against effects of ACh than BaCl2. Wait at least 30 minutes before eating, drinking anything else, or taking other medications. Wegovy belongs to a class of medications called glucagon-like peptide-1 (GLP-1) receptor agonists. When the FDA approved Wegovy (semaglutide) in 2021, it was the first new weight-loss medication on the market since 2014. If you miss a dose, take it as soon as remembered if within 4 days. No, Zepbound requires a prescription from a licensed healthcare provider. The long-term safety of dicyclomine hasn’t been fully established. Common side effects include dry mouth, dizziness, nausea, and blurred vision. Remember, staying informed and making conscious choices is key in achieving lasting health goals. I found my trial informative but also enlightening about individual reactions to medication. After 2 weeks, if your symptoms don’t improve, or if you’re unable to tolerate 80 mg of Bentyl per day, your healthcare provider may have you stop taking it. In studies in rats at doses of up to 100 mg/kg/day, dicyclomine produced no deleterious effects on breeding, conception or parturition. Reproduction studies have been performed in rats and rabbits at doses up to 33 times the maximum recommended human dose based on 160 mg/day (3 mg/kg) and have revealed no evidence of harm to the fetus due to dicyclomine. Dicyclomine for Weight Loss However, if weight loss plateaus early, it might indicate a need for dose escalation under medical supervision. Many people start their journey with the lowest dose, which is 2.5 mg, and wonder about its potential impact on their weight loss goals. Reproduction studies have been performed in rats and rabbits at doses up to 33 times the maximum recommended human dose based on 160 mg/day (3 mg/kg) and have revealed no evidence of impaired fertility or harm to the fetus due to dicyclomine. Even worse, you might be diverting attention from more effective weight loss strategies that actually work. Black patients also have an increased risk of angioedema (swelling of the hands, arms, face, mouth, or throat). Hyperkalemia (high potassium in the blood) may occur while you are using this medicine. These could be symptoms of an infection resulting from low white blood cells. Check with your doctor right away if you become sick while taking this medicine, especially with severe or continuing nausea, vomiting, or diarrhea. “Dicyclomine: 10 Powerful Facts About Its Benefits, Dosage & Side Effects!” The weight loss discussions surrounding dicyclomine often appear in online forums and social media rather than in peer-reviewed medical literature.No, it’s not approved for anxiety, though it may indirectly reduce stress by easing IBS symptoms.Mean half-life of plasma elimination in one study was determined to be approximately 1.8 hours when plasma concentrations were measured for 9 hours after a single dose.People covered by government-sponsored insurance, including Medicare and Medicaid, aren’t eligible for the discount program.Adequate and well-controlled studies have not been conducted with dicyclomine in pregnant women at the recommended doses of 80 mg/day to 160 mg/day.It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Dicyclomine was never designed for slimming down, and using it for that is a recipe for disappointment and health issues. It baffles me that myths about drugs spread so fast. There are misconceptions that dicyclomine automatically helps you shed pounds. But really, it’s best known for decreasing muscle spasms in the stomach and intestines. Other side effects not listed may also occur in some patients. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Some side effects may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Along with its needed effects, a medicine may cause some unwanted effects. Interactions between Dicyclomine and other drugs Dicyclomine works by relaxing the muscles in the stomach and intestines, which can alleviate symptoms such as cramps and bloating. Taking dicyclomine exactly as your doctor directs it is important, as taking too much or too little can affect its effectiveness. Acetylcholine is involved in the contraction of smooth muscle, including the muscles in the intestines. Dicyclomine is a type of medication known as an anticholinergic, which blocks the action of a chemical called acetylcholine in the body. It works by relaxing the muscles in the intestines and reducing the spasms that can cause these symptoms. When starting Zepbound or Wegovy, your dosage is slowly raised over time to help manage side effects and find the right dose. Both medications come in single-dose prefilled injections pens. While not mandatory, exercise boosts weight loss and health benefits. At similar low doses, it often shows slightly better weight loss in studies. At 2.5 mg, weight loss tends to be gradual, building momentum over time. The drug was never developed or studied for this purpose, and the FDA has not approved it for weight management. Third, some speculate that by altering digestive function, it might affect nutrient absorption or gastric emptying in ways that could theoretically support weight loss. Second, by reducing gastrointestinal cramping and discomfort, the drug might indirectly support weight management by making it easier to maintain a consistent eating pattern. The medication is available in 10 mg and 20 mg tablets, with 10 mg being a common starting dose. However, Wegovy’s manufacturer is seeking approval of a 7.2 mg injection dose, which is 3 times higher than the current highest available dose. Individual clinical trials also suggest that Zepbound may result in greater weight loss than Wegovy injections and pills. Results showed greater weight loss with Zepbound compared with Wegovy (20% vs. 14%) at 72 weeks (16.5 months). People covered by government-sponsored insurance, including Medicare and Medicaid, aren’t eligible for the discount program. Medicaid, including state-run and managed care plans Medicare, including original Medicare and Medicare Advantage plans Commercial plans (not including plans purchased through an ACA marketplace) In this article, we’ll cover everything you need to know—how Dicyclomine works, proper dosage, potential side effects, usage during pregnancy, and long-term safety. Dicyclomine, a trusted antispasmodic medication, is commonly prescribed to treat intestinal and stomach-related conditions such as Irritable Bowel Syndrome (IBS). Keep this and all medication outof the reach of children. Dicyclomine Hydrochloride Tablets, USP are available containing dicyclomine hydrochloride, USP equivalent to 10 mg of dicyclomine. A 37-year old female reported numbness on the left side, cold fingertips, blurred vision, abdominal and flank pain, decreased appetite, dry mouth, and nervousness following ingestion of 320 mg daily (four 20 mg tablets QID) for four days. It acts like a natural gut hormone called GLP-1, which has effects on your gut and the appetite center of your brain. Both come in injectable forms that are administered once a week and can cause similar side effects. One such medication is Zepbound (tirzepatide). There is no FDA guidance one the use of Dicyclomine in patients who are immunocompromised. Drug hypersensitivity including face edema, angioedema, anaphylactic shock, dermatitis allergic, erythema, rash There is limited information regarding Off-Label Non–Guideline-Supported Use of Dicyclomine in pediatric patients. However, clinical trials showed that within the first month, people lost about 2% of their starting body weight with Wegovy and about 3% with Zepbound. Which medication is more affordable can depend on your specific plan and health history. This gives your body time to adjust to Zepbound and find the right dose for you. Yes, if you need more help managing your body weight, it’s possible to switch from Wegovy to Zepbound. Both Zepbound and Wegovy are approved for weight loss. Conclusion: Should You Use Dicyclomine 20 mg for Weight Loss? They might consider lowering your dicyclomine dose or switching you to another medication. One study showed that people started to feel an improvement in symptoms like stomach pain and tenderness within 2 weeks of taking dicyclomine. The brand name Bentyl is available only as the injection form of dicyclomine that's given into the muscle for people who can't take the medication by mouth. There's also an injection form of dicyclomine that's available as brand name and generic; it's injected into the muscle for people who can't take pills by mouth. This medication is available as generic tablets, capsules, and liquid that are taken by mouth four times daily. 69% of patients on dicyclomine reported one or more adverse reactions as compared to 16% in the placebo group. Guidelines based on clinical evidence recommended dicyclomine as a pharmacological treatment of IBS, together with other antispasmodics such as mebeverine and alverine citrate. If you begin taking Bentyl and the side effects are strong, your doctor may be able to adjust the dose so you're more comfortable. To manage side effects effectively, incorporate fiber-rich foods gradually and avoid fatty meals. Monitoring for severe abdominal pain or vomiting is advised, with immediate medical attention if they occur. More serious but rare effects might involve gallbladder issues or pancreatitis. Combining the medication with calorie control enhances outcomes. The connection between dicyclomine and weight loss typically centers on a few proposed mechanisms. This broad mechanism of action is why dicyclomine carries multiple potential side effects and why its use requires careful consideration and medical oversight. Anticholinergic medications can affect various bodily systems, including the cardiovascular, nervous, and urinary systems. Dicyclomine hydrochloride is an anticholinergic medication approved by the FDA for treating functional bowel disorders, specifically IBS with symptoms including abdominal pain, cramping, and diarrhea. Before considering any medication for weight management, it’s essential to understand its intended purpose, mechanism of action, side effect profile, and the scientific evidence supporting its use. She has over 20 years of experience and has worked in several pharmacy practice settings, including at a community pharmacy as well as in ambulatory care, senior care, and pharmacy operations.The brand name Bentyl is available only as the injection form of dicyclomine that's given into the muscle for people who can't take the medication by mouth.This medication is available as generic tablets, capsules, and liquid that are taken by mouth four times daily.Zepbound stands out among options like semaglutide-based drugs due to its dual-hormone action.When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below.This medicine will add to the effects of alcohol and other CNS depressants (medicines that make you drowsy or less alert).Treatment may involve intravenous fluids and medications to reverse the effects of the overdose.Find out about treatment options like diet modifications, medications, and complementary and integrative medicine approaches.Make sure any doctor or dentist who treats you knows that you are using this medicine. If you’re struggling with persistent IBS symptoms, speak to your doctor about whether Dicyclomine might be the right option for you. There is a higher risk of side effects like confusion. Long-term use may increase side effects. Investigate any tachycardia before administration of dicyclomine hydrochloride. Dicyclomine Hydrochloride Tablets, USP are available containing 20 mg of dicyclomine hydrochloride, USP. Documented safety data are not available for doses above 80 mg daily for periods longer than 2 weeks. This medication can worsen prostate problems and lead to difficulty urinating. Use dicyclomine with caution if you have prostate problems. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. This medication passes into breast milk and may have undesirable effects on a nursing infant. Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products). What’s the typical Bentyl dosage for adults? While some individuals report appetite changes, these are not reliable or consistent effects, and the medication was not studied for weight management applications. During a weight loss consultation, a doctor should discuss the evidence base for any proposed treatment, explore evidence-based alternatives, and ensure you understand both potential benefits and risks. These medications have undergone rigorous clinical trials demonstrating safety and efficacy for weight management. Using medications off-label without clear medical justification and proper supervision increases the risk of adverse outcomes. If you do not experience relief, your healthcare provider may suggest alternative treatments like fiber supplements, probiotics, or different antispasmodic medications. It’s crucial to consult a healthcare provider before considering dicyclomine as part of your weight loss strategy. When considering dicyclomine for weight loss, it’s essential to be aware of its potential side effects and risks. Some people have reported using Dicyclomine for weight loss, but it’s essential to note that it’s not an approved use for this medication. FDA-approved weight loss medications may be appropriate under medical supervision when lifestyle modifications are insufficient. A 28-day supply is 4 prefilled pens or 4 single-use vials. Here’s a chart that explains some self-pay options (paying without insurance) — if you don’t have insurance or choose not to use your prescription plan — including using a GoodRx coupon. Whether you receive the medication at your local pharmacy or Eli Lilly’s online pharmacy will also influence what you pay. The cash price of Zepbound depends on whether you’re using the prefilled pens or single-dose vials as well as your dose. The list price for a 28-day supply of Zepbound is $1,086 as of January 1, 2025. Dicyclomine should be administered with caution in patients with hepatic impairment. Dicyclomine should be administered with caution in patients with renal impairment. Effects of renal impairment on PK, safety and efficacy of dicyclomine have not been studied. So long-term use of medications like Zepbound is usually recommended. Also, beware of counterfeit Zepbound or tirzepatide, particularly any of these medications that you can access without a prescription. Tricare’s new rules on weight-loss medication coverage take effect August 31, 2025. Fennel—whether as bulb, seeds, or essential oil—is often touted as a “miracle herb” for bloating, PMS, milk supply, and even weight loss. How overweight and obesity impacts your health. These estimates, derived from national MMIT coverage data, provide insight into health insurance coverage for each medication. This means the 28-day medication — which requires 13 fills for a full year of injections — could cost more than $14,000 annually without insurance. At publication time, Zepbound was not included in the Lilly Cares Foundation Patient Assistance Program, but other patient assistance programs may be able to help you afford this medication. She received her medical degree from the Louisiana State University School of Medicine and completed her residency in internal medicine at Emory University School of Medicine. During this time, he completed his clinical training in internal medicine, cardiology and clinical cardiac electrophysiology, served as chief cardiology fellow, and received the Kenneth M. Rosen Fellowship in cardiac pacing and electrophysiology from the Heart Rhythm Society. Dr. Breite divides his time between technical procedures, reading about new topics, and helping patients with some of their most intimate problems. Yes, but only under medical supervision. However, some patients may use it regularly under supervision for chronic conditions. This action makes it particularly useful in treating IBS symptoms, where the colon becomes overactive or hypersensitive. Dicyclomine hydrochloride is a medication that belongs to the class of anticholinergic and antispasmodic agents. In these trials most of the side effects were typically anticholinergic in nature and were reported by 61% of the patients. The most serious adverse reactions reported with dicyclomine hydrochloride include cardiovascular and central nervous system symptoms see WARNINGS AND PRECAUTIONS (5.2, 5.3). Large doses may suppress intestinal motility to the point of producing a paralytic ileus and the use of this drug may precipitate or aggravate the serious complication of toxic megacolon see ADVERSE REACTIONS (6.3). In this instance, treatment with this drug would be inappropriate and possibly harmful see CONTRAINDICATIONS (4). It is very important that your doctor check your progress at regular visits to make sure this medicine is working properly. You may have to take high blood pressure medicine for the rest of your life. Remember that this medicine will not cure your high blood pressure but it does help control it. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well. Many patients who have high blood pressure will not notice any signs of the problem. The principal route of elimination is via the urine (79.5% of the dose). Dicyclomine hydrochloride tablets, for oral administration, contain 20 mg of dicyclomine hydrochloride, USP. The required safety measures will enable you to receive therapeutic advantages from this medication safely. If you experience any side effects while taking dicyclomine, or if your symptoms do not improve, you should talk to your doctor to discuss other treatment options. Always consult your healthcare provider before starting or stopping any medication, and follow their guidance to ensure you are using dicyclomine safely and effectively. Treatment may involve intravenous fluids and medications to reverse the effects of the overdose. Tracking your intake and activity from day one helps gauge the dose’s impact. Before starting, discuss your medical history with a doctor to ensure it’s appropriate. This low starting point allows the body to adapt to the medication’s effects on the digestive system. It helps to reduce the symptoms of stomach and intestinal cramping. Consult a doctor today to find the best plan for you! Its primary role is treating IBS, and side effects make it risky for off-label use. Most agree it’s not a magic pill for fat loss. Zepbound is also being studied in certain people with heart failure, MASH, and chronic kidney disease. Wegovy has shown positive results for certain people with heart failure. Age can also affect which medication is prescribed. At the time of publication, Zepbound has not been added to the Lilly Cares Foundation Patient Assistance Program, which provides certain medications free of cost to qualifying people. But weight-loss medications can be costly, and not all health insurance plans will cover them. Zepbound (tirzepatide) and Wegovy (semaglutide) are popular medications for weight loss. For many people, Zepbound and Wegovy are effective medications for weight management. Since then, a number of weight-loss drugs have been rolled out to try to meet the high demand for these medications. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation. Adverse reactions are included here that have been reported for pharmacologically similar drugs with anticholinergic/antispasmodic action. Not all of the following adverse reactions have been reported with dicyclomine hydrochloride. Since dicyclomine hydrochloride has been reported to be excreted in human milk, DICYCLOMINE HYDROCHLORIDE IS CONTRAINDICATED IN NURSING MOTHERS. Because animal reproduction studies are not always predictive of human response, dicyclomine hydrochloride as indicated for functional bowel/irritable bowel syndrome should be used during pregnancy only if clearly needed. When beginning Zepbound, the 2.5 mg dose serves as an introduction to the treatment. It encourages the body to use stored fat for energy, contributing to weight loss. Over time, doctors may titrate the dose up to 15 mg based on response and tolerance. Starting at 2.5 mg helps patients acclimate without overwhelming side effects. Using medicines in this class with any of the following medicines is usually not recommended, but may be required in some cases. Using medicines in this class with any of the following medicines is not recommended. Dicyclomine is also available as an injection that's given into the muscle for people who can't take the medication by mouth. After one week, your prescriber might raise your dose to 40 mg by mouth four times daily. The typical starting dose is 20 mg by mouth four times daily. Dicyclomine is an anticholinergic medication that’s approved for irritable bowel syndrome (IBS). Dicyclomine’s price at certain pharmacies is as low as $21.58 for a 30-day supply with a free GoodRx coupon. Dicyclomine is available only as a generic medication. Be sure to store dicyclomine in a child-safe container that’s out of reach of children who live in or visit your home.