A major point of interest among fans and media has been whether Kelly Clarkson used the diabetes medication Ozempic to lose weight. It is her sheer honesty about food, body-shaming, and body images, which made fans love her. What she never comes to terms with is the wildly unrealistic body standards that she was upheld when she became famous. Luckily, she came out of that black hole and realized that nobody could tell her what to do. One reason fans love her aside from her fabulous voice is her grace and honesty in the face of unending discussions about her weight. In turn, treatment is targeted towards improving insulin resistance, weight loss, decreasing luteinizing hormone (LH) and follicular stimulating hormone (FSH) ratios, and excess androgens. Concomitantly, decreased insulin production inhibits 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase activation and stimulates HMG-CoA lyase involved in ketone production. The mean weight change for participants assigned to the LCD group was -5.1 ±8.7 kg, while it was -3.1 ±8.4 kg for the conventional diet group. The sustainability of the diet has been called into question, and the prognosis of the diet’s effects after discontinuation must be examined. KD has been shown to effectively lead to weight loss, reduction in hyperinsulinemia, and improvement in insulin sensitivity. These substances have the potential to disrupt nutritional ketosis and exacerbate propylene glycol poisoning and metabolic acidosis .The only FDA-approved weight loss supplement, alli, contains orlistat and blocks approximately 5% of consumed fat.The ketogenic diet initiates the increased production of ketone bodies (i.e., β-hydroxybutyrate (the main ketone body), acetone and acetoacetate) in the body.It also enhances metabolism and improves insulin sensitivity, helping stabilize blood sugar levels and prevent energy fluctuations.In the absence of knowledge on the metabolic mechanisms that underpin the two diets, greater body mass loss on a KD has been attributed either to spontaneous reduction in energy intake 8,12,14 or reduced hunger and/or increased satiety.These gummies caught my eye for their keto-friendly formulation and easy delivery method.When selecting keto gummies, it’s important to consider several factors to ensure you choose a product that aligns with your goals, preferences, and dietary needs.It is essential to understand that while Keto ACV Gummies may support weight loss efforts, they are not a magical solution for shedding pounds without making necessary lifestyle changes. Verifying information from reliable sources and consulting healthcare professionals can provide a more accurate understanding of these gummies’ potential role in a weight management journey. While these gummies can be a convenient aid in supporting weight loss efforts, it is crucial to approach them with caution and critical thinking. They are dietary supplements that may support weight management when used responsibly. However, for optimal results, pairing the gummies with a low-carb, high-fat diet is recommended. Moreover, while Keto ACV Gummies can be a helpful aid in a weight loss journey, they are not a substitute for a balanced diet and regular exercise. A restriction of carbohydrate, either by fasting or by restricting dietary carbohydrate, results in reduced insulin levels, thereby reducing lipogenesis (the creation of fats) and fat accumulation. Animal studies indicate that the short chain fatty acids acetic acid and butyric acid, increase ketone body concentrations. No credible doctor, hospital, university, or celebrity has ever endorsed these keto gummies for weight loss. Keto Ripped ACV Gummies are a dietary supplement combining Apple Cider Vinegar (500mg) and Beta-Hydroxybutyrate (BHB)—a ketone body. 'Shark Tank' Keto Gummies Are A Scam. Yet, Google Keeps Letting Scammers Run Search Ads. Understanding her journey offers valuable insights into achieving and maintaining a healthy weight, dispelling common misconceptions surrounding celebrity weight loss narratives.Elevated levels of fructose metabolites (including uric acid and lactate) are closely related to oxidative stress and local inflammatory reactions in tissues and organs 114,115.Kelly Clarkson’s weight loss journey had a substantial impact on public perception and attitudes towards weight loss and body image.In this report, the long-term effects (up to 10 years) of a ketogenic diet on outcomes in advanced cancer in 55 cases at our department in Osaka University Hospital were examined.Some news media reported that Kelly admitted that she was diagnosed with prediabetes which could be a possible motivating factor for weight loss.According to the American Heart Association (AHA), the ketogenic diet also raises some controversy related to CVD and has poor alignment with the AHA dietary guidelines .They found that women with restricted carbohydrate intake, defined as less than the fifth percentile among the control group were 30% more likely to have infants with neural tube defects (Odds ratio of 1.30, 95% (1.02, 1.67) p28 Women who plan to become pregnant should be advised to avoid restrictive low-carbohydrate diets. So with that out of the way, the question one needs to ask is do these apple cider vinegar gummies do anything for weight loss or keto? Keto ACV gummies have gained significant attention for their convenience, potential health benefits, and ability to complement a low-carb or ketogenic lifestyle. The goal is to provide metabolic support, especially for people on a ketogenic diet, while avoiding the acidity and inconvenience of liquid ACV. These ads often lead to misleading websites that present bogus testimonials and unverified claims, suggesting that the gummies can melt belly fat or cause rapid weight loss without any real effort. In a direct, dose-matched comparison, Kesl and colleagues evaluated the effects of ketone esters, salts, MCTs, and MCT + KS on blood BOHB in Sprague-Dawley rats at a dose of 5 g/kg. Severe mental illness, similar to impaired cognitive ability and aging, may lead to reduced compliance in adequate water consumption and constant use of prescribed electrolyte and vitamin supplement crucial to maintain a good safety profile especially during a VLCKD among all KDs, thus increasing the risk of side effects. Elderly patients might find remembering these challenging, especially when impaired cognitive ability is present, possibly posing at risk of cardiac arrhythmias and vitamin deficiencies. Further studies are needed to be conclusive on the role possibly played by the KD in active or severe infections, and a cost‐to‐benefit ratio should be assessed on a patient‐to patient basis until clearer evidence is reported. Current evidence is insufficient to determine whether patients with respiratory failure may safely consume a KD, but an unexpected, beneficial effect both in lean and obese patients has been suggested. It is characterized by a higher carbohydrate restriction and high-fat intake with no restrictions on calories and protein. The second type contains medium-chain-triglyceride (MCT) like caprylic acid, capric acid, caproic acid, and lauric acid , with 70% of energy uptake from fat including 10% long chain triglyceride (LCT) fat and 60% MCT fat, 20% from carbohydrate, and 10% from protein. Thus, in this diet, fat intake provides 90% of the energy, which may be difficult and intolerant to the public . Considering the number of studies on this topic, there is a clear need to summarize potential mechanisms through which KD can improve cardiovascular health and control cell proliferation. The results demonstrated that the ketogenic diet-fed fibrotic mouse group had markedly increased serum alanine aminotransferase (ALT) levels compared with the CCl4-alone group (Figure 1B). It is reported that ketogenic diets are highly appreciated in the therapy of epileptic seizures and reduces 50% of the frequency of seizures after using it for 3 months . Since a different ketogenic diet composition may exert different metabolic effects, more evidence is necessary to clarify the effects of a ketogenic diet on disease treatment. Through ketogenic diet consumption, β-hydroxybutyrate (bHB) and acetoacetate (AcAc) are two ketone bodies that are mainly produced in the liver. By providing the body with a readily available source of ketones, Trimax Keto can help you to reach and maintain a state of ketosis far more effectively, as you should expect. We get something a little bit special with Nucentix Keto-GMY BHB Gummies, which are, of course, specially formulated to support you as you follow your ketogenic diet. Also, as we’ve seen, ketosis can lead to digestive complaints due in large part to a lack of fiber (though high fat levels make up for this a bit). Key elements of Kelly’s diet included lean proteins, vegetables, whole grains, and healthy fats.As of March 2023, the patient was 55 years old, continues on a ketogenic diet, and was in good general condition.Ketogenic diets can also lower blood glucose, although their efficacy typically wanes within the first few months.This could contribute to improving health and reducing the risk of death among many millions of people worldwide.MCT products are widely available for users to purchase for the apparent “Keto” benefits obtained for weight loss; however, the question of whether these MCT products can enhance cognitive capacity in people with and without cognitive deficits remains questionable.The general perception is that gummies raise blood sugar levels, but the truth is that gummies with the right formula can control glycemic response.Since a different ketogenic diet composition may exert different metabolic effects, increased sample size and more experimental designs are necessary to clarify the effects of the ketogenic diet on disease treatment.The first way is the oxidation of fatty acids to acetyl-CoA, which are the building blocks of the ketone bodies, or by conversion of amino acids directly into ketone bodies (9). This section focuses on the key takeaways that highlight the importance of a holistic approach to health and well-being. One of the most inspiring aspects of Kelly’s journey is her emphasis on self-love and body positivity. A licensed therapist can help address emotional or psychological factors that may contribute to unhealthy eating habits. The narrative surrounding her weight change frequently omits the critical elements of long-term lifestyle adjustments and mental well-being, which played substantial roles in her journey. It was a reminder that so many people—especially women—have up-and-down journeys with weight. Incorporating Keto Gummies into a Diabetes Management Plan Kelly’s journey toward a healthier lifestyle began with recognizing the factors contributing to her desire for change. The turning point in Kelly’s journey came when she made a commitment to lead a healthier lifestyle. Her journey from being a global pop icon to embracing a healthier lifestyle has captivated fans and fitness enthusiasts alike. One of the initial challenges Clarkson faced was finding a balance between her hectic schedule and a healthy lifestyle. An integral part of her journey involved focusing on mental health and self-acceptance. Supports Post-Workout Recovery In the previous report, 55 patients met the entry criteria and were enrolled in the trial. This study was approved by the genome committee of Osaka University (Approval number 526). In such a retrospective, non-randomized study, the standard Kaplan–Meier estimate may be biased due to confounding factors. In the present study, the same analysis was performed, looking at long-term outcomes. In a previous report, we reported survival curve stratification based on albumin, blood glucose, CRP at three months, and the KD-ABC (Ketogenic Diet Albumin Blood Glucose CRP) score, taking these variables into account . A few studies have demonstrated the impact of glucose on brain activation during cognitive workload and resting-state, most of which have noted increases in activation amplitude in response to higher induction of physiological glycemia . Glucose is the primary energy source for all body tissues, and consequently, glucose metabolism is tightly regulated by hormonal factors and substrate availability . In addition, IF effects could be more prominent in certain domains , which could be missed in many research designs. In a review by de Cabo and Mattson , which emphasized the favorable effect of IF on cognition, most of the included studies represented calorie-restricted protocols rather than IF, perhaps making the studies less comparable. Others tested fasting in a single-day setting 73,78,81, which could have been met with psychological difficulties that require adaptation and impact the study outcomes . Recent studies showed the role of ketone bodies as an important fuel source for the heart .Together, we can support each other in achieving our weight loss goals and living healthier, happier lives.This approach not only aids in weight loss but also promotes a healthy, active lifestyle.From a dietary and nutrition management perspective it is key that people living with diabetes are supported to make healthier food choices using an individualised approach, appreciating that no one size fits all.Ketone bodies are an efficient alternate fuel source that could compensate for the deficient glycolytic metabolism upon their supra-physiologic availability in the blood (ketosis), which, in turn, could promote cognitive benefits and tackle disease progression.The group that continued the ketogenic diet for more than 12 months showed a significantly better OS than the group that did not.This educational article aims to answer frequently asked questions about keto gummies, providing evidence-based information to help you make informed decisions about these supplements.In a randomized controlled trial performed at the outpatient care of the Philadelphia Veterans Affairs Medical Center among adults of ≥18 years old with a BMI of ≥35 kg/m2, 64 participants were assigned to an LCD and 68 participants were assigned to a conventional diet.However, the ketogenic diet was substantially lower in calories, which may have independently reduced insulin resistance (84). Most manufacturers recommend a dosage of 2-4 gummies per day. The appropriate dosage for Keto ACV gummies varies depending on the brand and formulation. Yes, most Keto ACV gummies do contain calories, typically ranging between calories per serving (usually 1-2 gummies). The study is not directed toward a specific region or country. Cholesterol levels may also increase by approximately 30% . Females were slightly more than males (52.7% vs. 47.3%), and more than one-half (55.3%) of this study population aged years. Nonetheless, there are concerns of possible adverse events following exposure to the dietary patterns, which should be considered. Although the Mediterranean diet is recommended by many guidelines, it is not easily accessible for many patients. Although one study showed no relationship between IF and pathologic eating patterns in people with no history of eating disorders,65 two studies in individuals with eating disorders showed an increase in food intake following 6 h and 14 h fasts.69,70 A longitudinal study also reported that self-reported fasting was a predictor of eating pathologies and recurrent binge eating.71 In the clinical trials of IF in patients with NAFLD, most studies reported that no significant adverse events were observed. Notwithstanding, IF may be a viable alternative for patients who are unable to maintain weight control by daily caloric restriction. This meant paying attention to her body’s hunger and fullness cues, savoring each bite, and eating slowly. “Mindful eating helps you develop a healthier relationship with food and can prevent emotional eating,” says nutrition therapist Mark Thompson. “I know the industry loves the weight gone, but for me it wasn’t (about) the weight,” she said. 41-year-old Kelly’s chubby and plump body is now turned into tonned and slimmer flesh. Not only Kelly’s divorce from her husband but her parent’s divorce also majorly affected her emotional state and she started to gain a lot of weight. Keto ACV Gummies combine a range of ingredients designed to enhance their health benefits, particularly for those following a ketogenic diet. The fat-burning effects of keto gummies are likely to be modest at best. No, keto gummies—like all dietary supplements—are not FDA-approved for safety and effectiveness before marketing. A well-formulated ketogenic diet was adapted by Phinney and Volek, from the ‘standard ketogenic diet’, in order to address some of the limitations to promote long-term sustained nutritional ketosis through enhanced adherence. Until there is consistency of a definition, the recommendation of a ketogenic diet for diabetes management cannot be endorsed for public health. Consequently, the significant alteration of other macronutrients within a ketogenic diet (fat and protein) results in confounding variables which make distinguishing the accrediting factor of a ketogenic diet on glucoregulatory control challenging. Conclusion are keto gummies real Additionally, KD can be used in the setting of Alzheimer's disease, with an increase in cognitive function (18), and therapeutic effects have been proposed also for neurologic conditions characterized by substantial motor dysfunction (19). In these patients, KD caused a significant improvement of seizure frequency (17). Insulin reduction and improvement of insulin sensitivity contribute to the clinical effects of KD. A different type of adverse effects may be seen in long-duration KD, including gastroesophageal reflux disease, uric acid increase, electrolyte imbalance and hyperlipidemia (11). Exogenous ketones are unlikely to be ketogenic per se, and may inhibit ketogenesis, however, the rapid and substantial elevation of BOHB offers potential to mitigate effects of keto-induction, and thus, could play a role in improving adherence to a ketogenic diet. There has, however, been little research performed on the application of MCTs to classic ketogenic diets and whether, if applied, they would; (a) improve time to NK, (b) result in significantly higher levels of BOHB, and (c) significantly reduce symptoms of keto-induction. In a 12-month study, a classic ketogenic diet resulted in higher levels of BOHB (and acetoacetate) over all time periods (three, six, and 12 months) but this was only statistically significant at three and six months (p Neal et al., 2009). Will Keto ACV Gummies Improve My Digestion? In a double-blind placebo-controlled trial, Ota et al. (2016) suggested that acute ketosis induction can lead to swift cognitive improvements in older adults free from dementia . MCT products are widely available for users to purchase for the apparent “Keto” benefits obtained for weight loss; however, the question of whether these MCT products can enhance cognitive capacity in people with and without cognitive deficits remains questionable. Whether a single-dose of 40 mL of MCT was applied or three months adherence to a daily 20 g of 95% caprylic acid (C8) MCT , cognitive benefits in those with mild to moderate AD were absent in ApoE4 carriers compared to ApoE4− despite the marked rise in ketone bodies achieved by both interventions. Written informed consent was obtained from the patients to publish this paper. First, this was a retrospective study, and it was not possible to adjust for unmeasured factors. Social functioning is considered to be a psychosocial factor that supports the continuation of diet therapy, and appetite loss is considered to prevent the continuation of a diet that is not familiar to the patient. Global health status , physical functioning , role functioning , social functioning , pain , and appetite loss in the EORTC-QLQ30 are known to contribute to survival. Manufacturers of dietary supplements are required to follow Good Manufacturing Practices (GMP) to ensure product quality, purity, and consistency. While the FDA does not approve or review dietary supplements before they are marketed, it imposes certain requirements to ensure product safety and accurate labeling. In the United States, dietary supplements like Keto ACV Gummies are regulated by the Food and Drug Administration (FDA). The legal framework surrounding dietary supplements and gummy products plays a critical role in addressing potential scams related to Keto ACV Gummies. Tsujimoto et al., in a population-based study on 9778 participants aged over 20 years, showed that insulinemia was an important risk factor for cancer death in individuals with and without obesity . KD not only reduced the serum concentration of glucose but also reduced the serum levels of insulin and insulin-like growth factor 1 (IGF1), which are involved in tumorigenesis, and this can have a synergistic effect . Part of these inhibitory effects is through KD’s effect on glucose metabolism in cancer cells. Various mechanisms have been proposed for the inhibitory effects of KD on the growth of tumors and cancer cells. Several studies have demonstrated that there was no significant change in cardiac indexes, including cIMT and elastic properties of the carotid artery, aortic strain, the stiffness index, and distensibility after short- and long-term KD in epileptic children 57,58. As such, it’s all there to enhance ketosis and fuel the body with an efficient energy source. It’s a very good idea to include some form of exogenous ketones as you switch into ketosis, and even potentially thereafter if you still feel you benefit from them. You’ll see a pattern beginning to emerge – similar templates, similar DNA, as all the top keto gummies look to use similar ingredients to achieve similar ends. And, happily, I recently got the opportunity to review a batch of some of the best keto gummies on the market. Keto gummies can make a huge difference to the success of your keto diet. Although ketogenic diets are popular and patients show great interest, their use must be approached with caution. Diet composition likely plays an important role in the lipid changes seen in patients adhering to a ketogenic diet, so a high-quality diet with adequate intake of fruits and vegetables and low intake of saturated fats would be preferred. In this study all 28 subjects that were enrolled received ketogenic diet counseling with a goal of less than 20 grams of carbohydrates per day. This study found that compared to low-fat diets, low-carbohydrate diets participants lost 2.17 kg more than the low-fat diets (95% CI −3.36, −0.99).13 However, the duration of some included studies was only six months. Epilepsy is a serious and costly health problem worldwide and includes estimated indirect and direct costs annually of around EUR 15.5 billion in Europe and USD 15.5 billion in the United States . Regardless of the country’s income, the public health burden of epilepsy carries a high risk of disability, economic loss, social isolation, and premature death . Epilepsy is a chronic brain disorder that is characterized by recurrent seizures, which are short episodes of involuntary movement that can affect part or all of the body, sometimes accompanied by loss of consciousness and control of bladder or bowel function. Taking more gummies than directed does not accelerate weight loss and may lead to adverse effects. Another claim involves unsubstantiated health benefits, such as curing medical conditions or providing long-term weight loss without proper diet and exercise. In summary, the appropriate dosage of ACV gummies for weight loss will depend on the specific product you are using and your individual health needs. By planning her meals in advance, she was able to avoid last-minute unhealthy choices that could derail her progress.To make the most of ACV Keto Gummies for weight loss, it’s important to incorporate them into a well-rounded weight loss routine.So realistically, even if the probiotics were helpful, you’re getting an absolutely minuscule amount of probiotics, certainly not enough to be beneficial for health.Here are the tools we recommend using to see if you’re truly in ketosis.There are numerous keto-friendly salty snacks that can come in handy, but chicharrones (known as pork rinds) are one of the snackiest we could think of.A feasibility study conducted by Chow et al. demonstrated that a time-restricted eating regimen with approximately 8 h of unrestricted eating can reduce eating occasions, and consequently weight, in non-diabetic adults with overweight and obesity . Her weight loss journey has not only been a personal achievement but also a beacon of motivation for millions. As we delve deeper into her weight loss strategy in the next sections, we’ll uncover the specific approaches and methods she employed in her successful transformation in 2024. In 2024, Kelly Clarkson embarked on a remarkable weight loss journey, adopting a comprehensive strategy that was both effective and sustainable. Her story is a powerful reminder that weight loss is as much a mental journey as it is physical. Kelly Clarkson’s weight loss journey in 2024 was a testament to her dedication and resilience. As a result, many people have turned to keto supplements, like keto gummies, to help them achieve their weight loss goals. This has been observed in the pediatric epilepsy community, where a ketogenic diet was used as a treatment for epilepsy in children, and nephrolithiasis was listed as one of the side effects . Increased acid production from a ketogenic diet may cause metabolic acidosis and related issues, including weakened bone health . The idea of the ketogenic diet making a comeback as a quick weight-loss strategy is very recent . As some patients find carbohydrate restriction difficult leading to low long‐term adherence11 and as exogenous ketosis can independently improve glycaemic control (even after a carbohydrate challenge12), there exists a clinical niche for a safe exogenous ketogenic intervention in T2D. Thus, most of these participants adopted a ketogenic diet to lose weight. As shown in Figure 2, most respondents (90.3%) felt happy about adopting a ketogenic diet, and 81.9% of them would recommend this diet to anyone who wants to lose weight. Table 4 summarizes the overall self-reported perception of the respondents about their physical and mental health in their first month of the ketogenic diet. Figure 1 displays the change in weight in response to adopting a ketogenic diet. A retrospective cross-sectional study was conducted among people who experienced or still practice a ketogenic diet. Moreover, BHB was shown to affect microbial-mediated immunomodulation in addition to its ability to inhibit the NLRP3 inflammasome with consequent anti-inflammatory effects (80). The alteration of gut microbiota may have downstream consequences for immune cells, reducing levels of intestinal TH17 cells (80). Data obtained from mice models suggest that, reducing the colonization levels of gut bacteria, KD may mediate the lack of intestinal Th17 induction (80). At each visit, anthropometric measurements were made, by the same PI, and a venous blood sample was obtained for the assessment of thyroid function. Physical activity was assessed by calculating a metabolic equivalent (MET) score from the validated global physical activity questionnaire (GPAQ) , which was completed at the end of each week throughout the study. The participants were asked to also maintain the same level of physical activity (habitual and structured) throughout the study. Eligible participants were asked to maintain the same level of physical activity throughout the study, which was monitored using the standardized global physical activity questionnaire (GPAQ) . The Pittsburgh Sleep Quality Index (PSQI) and the General Health Questionnaire (GHQ) were used to assess quality of sleep and psychological health, respectively. Ketosis is a metabolic adaptation to allow the body to survive in a period of famine. Research on the diet’s effectiveness in treating obesity or diabetes is limited. Therefore, an alternative diet might be a more appropriate approach to managing metabolic abnormalities. Moreover, other non-dietary factors such as physical activity can alter the degree at which ketosis is reached and influence the physiological response to a ketogenic diet . Therefore, individuals who follow the ketogenic diet may think they are achieving ketosis but may require further carbohydrate restriction. The search for the correct definition of ketogenic diets’ suitability for prescription is further complicated by the fact that the optimal distribution and intake of the other macronutrients (protein and fat) for individuals with diabetes also remains inconclusive. A key barrier that healthcare professionals face with recommending, counselling about and ‘prescribing’ ketogenic diets for diabetes management is that there are considerable inconsistencies of its definition in the scientific literature, with no international consensus reached. Other concerns of this dietary practice surround the limitations of fibre and micronutrient-rich foods of a ketogenic diet , including fruit and vegetables, that have been suggested to be beneficial for postnatal outcomes and reduced adverse pregnancy events in epidemiological studies . Sugar and sweets are mostly banned from the keto.This is consistent with previous reports in rodents and indeed humans and is thought to be mediated by changes in hepatic insulin sensitivity.At face value, the ketogenic diet appeared beneficial with lower plasma glucose after a 6 h fast compared with the other two diets.No changes were observed in HbA1C nor insulin sensitivity, possibly due to the initial non-diabetic characteristics of the study participants .For instance, all the participants who were classified as moderate AD in the Taylor et al study have dropped out due to caregiver burden, and the results only represented those with very mild and mild AD .Kelly Clarkson’s weight loss journey has contributed significantly to the broader conversation about realistic and healthy fitness goals.Simpli ACV Keto Gummies combines apple cider vinegar and keto-friendly ingredients to support a ketogenic diet.Ketogenic diet has been used in patients with difficult-to-treat epilepsy since 1921, with minor changes in recent years . Biochemical and molecular changes have also been reported; animals on KD had higher expression of monocarboxylate transporter 1 (MCT1) and MCT4 at the PFC , which are fundamental transporters that allow for cellular and neuronal entry of ketones . They aid in expanding on existing ketogenic research models research and pave the way for clinical applications. At the molecular level, ketosis can produce an efficient antioxidative effect by enhancing mitochondrial biogenesis and reducing reactive oxygen species through numerous modulations of intracellular signaling factors, such as the nuclear factor erythroid 2-related factor 2 (Nrf2) and AMPK/mTOR pathways. Physiological ketosis achieved by KD is believed to be the core process responsible for favorable neurological outcomes . As we unpack Kelly’s story, we will highlight the importance of support systems, mental health, and the impact of her journey on her overall well-being.It is a high-fat diet, so there is much less concern about exceeding the percentage of energy from fats than with other diets.It is possible that cognition can only be improved in those with initial cognitive deficits, and that younger and cognitively intact persons may not experience cognitive enhancements with ketosis.Taken together, available evidence suggests that a VLCKD, with the profound weight loss usually obtained, might be an effective tool to manage patients with obesity and mild kidney failure.The effects of the ketogenic diet on the vascular endothelium are illustrated in Figure 2.However, for optimal results, pairing the gummies with a low-carb, high-fat diet is recommended.To further evaluate the effectiveness of keto gummies, it’s important to examine the scientific evidence and research studies related to their use.Clarkson’s approach to weight loss as a gradual, health-focused process makes her a role model for sustainable health changes.The behavior of the gelatin gels can be strongly influenced by the presence of co-solutes such as sugars, including polyols and/or other carbohydrates. In epidemiological studies, diets high in saturated fat, trans fat, simple sugars, and animal protein (especially from red and processed meat) (57) and low in dietary fiber and omega-3 fatty acids (62, 68) are thought to contribute to NAFLD. Several clinical trials have compared low-fat and low-carbohydrate hypocaloric diets in overweight or obese adults and found similar reductions in intrahepatic fat (64–66). In other clinical trials with ketogenic diets, diabetes medications are frequently reduced or eliminated (21, 36–43). While on the ketogenic diet, insulin sensitivity was impaired when participants were challenged with a baseline diet meal (50% carbohydrates) (45). In a separate study, the fecal microflora profiles of children with refractory epilepsy showed reduced diversity, with reduced Firmicutes and Actinobacteria levels and elevated levels of Bacteroidetes following 6 months of ketogenic diet treatment . During ketogenic diet treatment, body energy is generally generated by the oxidation of fatty acids in mitochondria, resulting in the production of large amounts of acetyl-CoA. Although the anticonvulsant mechanisms of ketogenic diet are not still completely understood, it is believed that ketone bodies and polyunsaturated fatty acids presumably play a major role in the anticonvulsant effect of ketogenic diet. In the latest meta-analysis study in children and adolescents with refractory epilepsy after a classic ketogenic diet, the percentage of patients whose seizure reduction ≥50% was 62, 60, 52, 42, and 46% in 1, 3, 6, 12, and 24 months of diet, respectively . We will explore her background, including previous struggles with weight and the public’s perception, which sets the stage for the significant shift she experienced in 2024. Kelly Clarkson’s background and her experiences with weight gain and loss have been an integral part of her public persona. A clip and comments promoting the release of Clarkson’s latest album on her real Instagram account in June have been edited to add fake promotions for the diet product. Obviously my body doesn’t do it right.” The Grammy winner also performed her new single, “Where Have You Been,” live for the first time. During prolonged fasting, some tissues, such as muscle, can directly metabolize free fatty acids released from adipose stores. The large number of studies, authors, journals, and indications found illustrates the broad consideration and intensive investigation of the KD. Another limitation is that the two most common topics, overweight/obesity and diabetes mellitus, are umbrella terms. In the present review, studies from the last five years dealing with the KD were specifically analyzed to obtain a current overview. The average seizure frequency after 4 months compared to baseline was significantly lower in the ketogenic diet group (56%) than in the care as usual group (99%). The effectiveness of the ketogenic diet remained stable for 3 to 6 months, and the diet was not interrupted due to tolerance . The Pires’ group demonstrated the effectiveness of a ketogenic diet in the treatment of infantile spasms as a third-line therapy after vigabatrin and steroids. In addition, the ketogenic diet is the therapy of choice for GLUT1 deficiency syndrome and pyruvate dehydrogenase deficiency 15,16. The rates of effectiveness of a ketogenic diet in difficult-to-treat epilepsy for adults ranged from 13 to 70%. It is worth mentioning that KD may cause deficiencies in some micronutrients in patients, and patients who are exposed to nutritional deficiencies may exacerbate their nutrition status if they adhere to such diets . Liśkiewicz et al., in an animal study that evaluated the effects of long-term KD treatment on kidney cancer, showed a pro-tumor effect of this diet that aggravated the disease . Vidali et al., in an animal study on 10 CD-1 nu/nu mice models of renal cell carcinoma with features of Stauffer’s syndrome, showed that KD administered for two weeks led to severe weight loss and liver dysfunction . In a case report study of women aged 65 years, it was reported that two months of adherence to KD led to a 20% reduction in body weight, but no brain tumor tissue was detected . Woodhouse et al., in a clinical study with 29 patients, evaluated the effects of KD plus temozolomide and radiation on tumor progression six months after the completion of radiotherapy on magnetic resonance image (MRI) scans. Other neuroprotective properties of the ketogenic diet may mediate the inhibition of apoptotic factors such as caspase 3 34,35 (Figure 1). It has been observed that ketogenic diet can upregulate calbindin which has neuroprotective potential through its ability to buffer intracellular calcium . It has been suggested that the negative consequences of these neuropathological processes can be improved by means of a ketogenic diet (Figure 1). It has been shown that in animals without a functional noradrenergic system, the ketogenic diet did not show anticonvulsant capacity . Safety Concerns Associated with Weight Loss Gummies Late-onset adverse effects include hyperuricemia, hyperlipidemia, and kidney stones (16). The main side effects of KD treatment in children are constipation, vomiting, lack of energy, and hunger (73). There are also some side effects of the long-term implementation of a KD in children. In summary, modulation of the gut microbiota may be a new target for therapy in ASD patients. While Dr. Oz is a well-known figure, it’s crucial to approach all health endorsements with caution and perform thorough research before purchasing any product. Keto Gummies should complement a balanced diet and exercise regimen rather than replace them. Some potential side effects include digestive discomfort or allergic reactions, depending on the ingredients. While some users report positive effects, the effectiveness of Keto Gummies can vary based on individual factors. The authors of another RCT also studied the effect of a ketogenic diet in obese children and adolescents. Another randomized controlled trial, however, reported a beneficial effect of the ketogenic diet on the lipid profile, including a reduction in LDL fraction cholesterol. It is worth noting that this is one of the studies in which there was no weight loss, significantly improving the lipid profile in the body. Another randomized controlled trial among trained men, on the other hand, showed no significant differences in lipid profile changes between ketogenic (KD) and non-ketogenic (NKD) diets . At the same time, it is worth mentioning that these results were due to the simultaneous use of the low-calorie ketogenic diet (LCKD) with continuous positive airway pressure (CPAP). The demands of celebrity life can be overwhelming, leading to stress that often contributes to weight gain or unhealthy eating habits. Maintaining weight loss over time requires a sustainable approach, which Clarkson seems to have adopted. So here we will discuss all of Kelly Clarkson’s secrets of quick weight loss and the methods she used in her life-changing journey. Although ketogenic diet therapy (KDT) has been in use for nearly one century for the management of epilepsy, the last two decades have seen a surge in clinical interest in using KDTs in the fields of neurology, oncology, obesity, diabetes, and performance enhancement, among many others.You’ll typically enter in ketosis when in a fasted state, are taking part in long, mid-level physical activity, or when following the kind of ultra-low-carbohydrate, high-fat diet that we’re talking about today – the ketogenic diet.Kelly Clarkson’s weight loss journey underscores the crucial role of adopting a healthy lifestyle for effective weight management.This may be particularly beneficial for those who may experience more challenges in adhering to strict diets (e.g., elderly adults, demented adults, or children).It has been shown that the KD can exert synergistic effects with antipsychotic drugs by modulating neurotransmitter systems, stabilising neuronal networks, and improving neuroplasticity.First identified as a feasible treatment for intractable epilepsy, the ketogenic diet (KD) has recently gained popularity thanks to growing evidence on applications such as weight loss, most importantly, but also NAFLD, cancer, neurologic conditions and chronic pain.No credible doctor, hospital, university, or celebrity has ever endorsed these keto gummies for weight loss.The beneficial above-mentioned effects of ketogenic diets on the values of inflammatory markers and CVD risk factors may also be due to the reduction of the total carbohydrate pool, not simply the elimination of simple sugars. The diet recommends avoiding items packed with added sugars and unnecessary additives, which can help in shedding excess weight. He believes that before modern agriculture, humans naturally followed a low-lectin diet which greatly benefited gut health and overall well-being. When Kelly shed 37 pounds, there were some rumors suggesting she might have used diet pills or other methods to lose weight. In an interview with ‘Extra‘, Kelly shared that her motivation to try this diet wasn’t just about weight. Clocking up her steps gives her "quite the workout," but Kelly says she hasn't lost weight for appearance sakes, but for her health. A reduction in inflammatory markers as a result of a low-carbohydrate diet was also cited by Tavakoli et al. . Evidence for the cardiometabolic benefits of carbohydrate restriction alone can be found in a study by Waldman et al. In addition, it increases C-reactive protein (CRP) levels, oxidative stress and blood viscosity. Too much added sugar in the diet can be one of the greatest threats to cardiovascular health. It is well known that simple sugars are one of the key pro-inflammatory dietary factors 100,101,102, which applies mainly to all simple sugars (by the manufacturer, consumer or food preparer). While it is clear that exogenous ketones increase serum BOHB, they are not ketogenic, and may, in fact, inhibit endogenous ketone production (Balasse & Neef, 1975). In a study using higher dosages (0.573 g/kg BW) in healthy male athletes performing an hour of bicycle exercise at 75% of maximal exercise intensity BOHB levels rose from 0.1 to 3.4 mmol/L (p Cox et al., 2015). They are considered to be a safe and effective way to increase ketone body concentrations (Hashim & Van Itallie, 2014). After ingestion of MCT at a dosage of 30 g MCT/m (Paoli et al., 2015) body surface area by nine children (in a study of seizure control), BOHB levels rose progressively after administration from a mean of 0.2 ± 0.1 mmol/L after an overnight fast to 1.05 ± 0.3 mmol/L at 180 min. Additionally, since insulin reduction leads to weight loss, all the anti-inflammatory effects of weight loss should be taken into account as well (Figure 1). In these circumstances, ketone bodies replace most of the glucose required by the brain, while liver gluconeogenesis provides the limited amount of energy needed by glucose-dependent tissues such as red blood cells, retina and renal medulla (7). The first way is the oxidation of fatty acids to acetyl-CoA, which are the building blocks of the ketone bodies, or by conversion of amino acids directly into ketone bodies (9). It can therefore be suggested that, at present, a ketogenic diet can be prescribed as a short-term solution for up to a year for glycaemic and health outcome improvement. The findings surrounding improvements in lipid profiles can lead us to suggest that ketogenic diets can improve physical markers of cardiovascular risk and other metabolic outcomes. However, a meta-analysis reveals that benefits of a ketogenic diet, including decreased triglyceride levels, increasing HDL cholesterol levels, and reduction of anti-diabetic medications usage can be observed for up to 12 months. Another fundamental question that has yet to be answered is the duration of which ketogenic diets should be prescribed for, and whether the ketogenic diet should be ‘prescribed’ as a short-term solution or a lifelong prescription for diabetes management. They may have some additional benefits in patients who can tolerate and adhere to the dietary patterns, such as reduction in liver fat, and to a lesser extent, reduction in liver fibrosis. IF is simple and relatively safe for most people, with fewer safety concerns compared with a ketogenic diet. Patients in ADF group had a lower daily energy intake, end-of-study weight, and total body fat mass. MCTs, meanwhile, convert rapidly into ketones in the liver and are an efficient fuel source — especially beneficial during workouts or mental focus tasks. In this 3-part guide, we dive into the science, side effects, and real-world questions surrounding Keto ACV gummies — starting with what benefits they truly offer. These scams typically promise rapid and effortless weight loss through unverified supplements or programs, often accompanied by fabricated testimonials and doctored images of the celebrities. The Kelly Clarkson and Dolly Parton Weight Loss Scam falsely claims endorsements from these beloved celebrities to promote a miracle weight loss solution. Marketers behind “KETO Extreme Gummies” know that many people are desperate for quick weight loss solutions. “It’s the same stuff you eat — I just use different ingredients,” she told Hoda Kotb of her diet.However, she shed 37 pounds in 2018 and revealed that it was a result of Dr. Steven Gundry’s book, The Plant Paradox, which discusses a lectin-free diet.MCTs promote ketonaemia and ketogenesis (useful to reduce the risk of night-time hypoglycaemic coma) in those with carnitine palmitoyltransferase deficiency, a rare genetic condition which inhibits the ability to produce ketone bodies from long-chain fatty acids (Bonnefont et al., 1989; Bougnères et al., 1981).In recent years, ACV Keto Gummies have emerged as a popular option for individuals seeking to support their weight loss journey.Considering the number of studies on this topic, there is a clear need to summarize potential mechanisms through which KD can improve cardiovascular health and control cell proliferation.For this reason, clinicians should carefully monitor pharmacotherapy as well as dietary therapy, which emphasises the importance of individualised and patient-centred pharmacotherapy.The focus then shifts to her weight loss regimen, including her diet, exercise routine, and the support systems that played a critical role in her success.Mushroom gummies are a growing trend, with potential to support health in several ways. The Grammy winner knows she made you look with her body transformation, which she credited to several factors including diet and exercise—as well as a GLP-1 weight loss medication. Kelly Clarkson’s weight loss transformation began with a major focus on her dietary choices. Slow and steady weight loss tends to be the healthiest and most sustainable way to lose weight, as it allows the body to adjust and helps maintain results long-term. There is also an RCT that examined the effect of omega-3 fatty acid supplementation in the Mediterranean ketogenic diet on some cardiovascular risk factors. The results confirmed the benefits of the ketogenic diet on triglyceride and HDL fraction cholesterol levels both after six months and a full year. The authors, therefore, concluded that the ketogenic diet in this case contributed to the worsening of the blood lipid profile in the women studied . The supply of substrates for tumour energy metabolism can be reduced by dietary manipulation (eg, ketogenic diet) or by pharmacological means at the cellular level (eg, inhibitors of glycolysis or oxidative phosphorylation). However, it has been shown that short-term ketogenic diets improve the lipid disorders that are characteristic of atherogenic dyslipidemia (56). These studies provide evidence to explain the actions of a ketogenic diet in the brain. In another study (30), it was shown that a ketogenic diet induced gene expression in the brain. Changes in the level of creatinine in obese patients during a 24-week ketogenic diet. Although RFA for lung metastases is not a standard treatment, it is performed at some centers mainly for patients who do not respond to continued standard treatment . Two colorectal cancer patients were alive, with an actual measured survival rate of 25.0%. The measured 5-year survival rate for Stage IV lung adenocarcinoma cancer patients diagnosed between 2003 and 2014 in Japan was 8.0% . Two lung cancer patients were alive with an actual measured survival rate of 33.3%. Nevertheless, our sample size had sufficient power to detect changes in body mass and thyroid hormones during the dietary interventions, and we believe that our findings add important insight into the litertaure. We recruited 11 healthy, normal weight individuals who fulfilled our study criteria and who were willing to partake in a challenging randomized crossover design study protocol. Although animal and human studies show that exposure to cold enhances the activity of brown adipose tissue (BAT) 67,68 which generates heat and helps to maintain body temperature, the role of BAT in diet induced thermogenesis and the maintainance of energy homeostasis remains controversial 69,70. Our findings of a significantly higher fT3/fT4 after the HCLF dietary intervention compared with after the KD dietary intervention is in line with some 63–65, but not all studies that have investigated associations between T3/T4 ratio with metabolic syndrome. Serum T3 levels were not reported in that study , but others have reported lower T3 levels following carbohydrate restriction 20–23. 😳 On a positive note, we have so many delicious keto desserts that you can still enjoy!KD’s beneficial effects have been observed in a range of conditions including epilepsy and other neurologic diseases, obesity, type 2 diabetes, polycystic ovary syndrome, and cardiovascular disease (see 22,23 for a recent review).The authors would like to thank Vicky Ball, Poonam Patel, Alison Campbell, Jill Woodford, Julie Jones, Dr Sushma Datla and Dr Petra Hanson, for their invaluable assistance during this study.And consult a registered dietitian nutritionist (find one at EatRight.org), a professional who can work with you to create a meal plan you can stick to.It is essential to be aware of the tactics used by these dishonest sellers and to recognize the red flags to avoid falling victim to keto gummies scams.The top 10 topics in the field of ketogenic nutrition with ≥5 studies or publications in the databases PubMed and ScienceDirect from 2019 to August 2024.Clarkson's new eating and exercise habits have contributed to the weight loss transformation that has people confusing her for other celebrities.Rather than relying solely on supplements, individuals are encouraged to make necessary adjustments, ensuring their keto diet is well-rounded and satisfying. Although the precise physiological mechanisms are unknown, the therapeutic effects of ketogenic diets are partially credited to the rapid and effective weight loss which is the most significant predictor of T2D remission . The ketogenic diet has been shown to be effective in promoting weight loss and improving blood sugar control, and the addition of apple cider vinegar may enhance these effects. The ketogenic diet, which is very high in fat and low in carbohydrates, is thought to simulate the metabolic effects of starvation by forcing the body to use primarily fat as a fuel source. She has cut out a significant amount of sugar from her diet and increased her vegetable intake,” they said. As we unpack Kelly’s story, we will highlight the importance of support systems, mental health, and the impact of her journey on her overall well-being. Before diving into her transformation, it’s important to explore the initial challenges she faced with weight and self-esteem. This realization marked the beginning of her commitment to embracing a healthier lifestyle and improving her self-image. In the present review, studies from the last five years dealing with the KD were specifically analyzed to obtain a current overview.One of the most profound impacts of her weight loss was on her cardiovascular health.In the absence of multivitamin supplements, individuals on low-carbohydrate diets are at risk of frank nutritional deficiencies (10).However, the absence of definitive research on the ability of keto gummies to sustain ketosis raises questions about their true impact.– Explain if Kelly followed a specific diet plan, such as keto, paleo, or a customized meal plan, and how it contributed to her weight loss.If you took a survey and asked people why they are following the keto diet, the majority of people would likely say it’s for weight loss.Typically, a protein intake of over 1.5 grams per kilogram of ideal body weight is considered a high-protein diet .The authors concluded that ketone bodies reduce myocardial glucose uptake and increase myocardial blood flow. Therefore, it is not surprising that meta-analyses of these trials would show little long-term weight loss, and little difference between diet groups. Most clinical trials comparing macronutrient-varying diets have employed low-intensity interventions, insufficient to produce significant long-term dietary change. However, recent research underscores a biological basis for body weight control, by which the metabolic effects of food, more so than calorie content of specific foods or nutrients, determine body weight over the long term. Contrary to expectation, adoption of a higher-carbohydrate (lower-fat) diet by the US public in the second half of the 20th century could have contributed to the increasing prevalence of obesity (2), a major risk factor for type 2 diabetes. Discovery of insulin in the 1920s enabled people with diabetes to control hyperglycemia on high-carbohydrate diets. Also they don’t do anything for keto. They shouldn’t be classified as a health food, but unfortunately a lot of places like Walmart do, which is misleading and confusing for customers. In fact, taking these regularly would more likely harm your health, just like eating candy every day might. Despite a lack of data specifically on ketogenic diets, it is well established in Mendelian randomisation studies which reveal not only that dietary saturated fat increases LDL cholesterol (LDLc) but also the subsequent deleterious impact of LDLc as a risk factor of coronary disease. This study also highlights the intra-variability in response to ketogenic diets; however, it affirmed that neither genotype pattern nor baseline insulin secretion affects weight loss. A recent study in patients living with T2D and obesity comparing the effects of 12 weeks of energy-restricted ketogenic diet compared to a conventional diet revealed significant improvements not only in metabolic parameters but also in mental health, physical functioning and pain . As of March 2023, at least 4 years and 5 months had passed since consent was obtained for patients with Stage IV lung cancer or colorectal cancer who had been on a ketogenic diet for at least 3 months. The results show that patients who were able to continue the ketogenic diet for a longer period had significantly better outcomes than those who were not. In this report, the long-term effects (up to 10 years) of a ketogenic diet on outcomes in advanced cancer in 55 cases at our department in Osaka University Hospital were examined. To the best of our knowledge, there is no evidence on factors contributing to longer persistence on a ketogenic diet in cancer patients. Figure 4A shows survival curves based on the Kaplan–Meier method for the two groups of patients on the ketogenic diet for more than 12 months and less than 12 months. Not to mention, the Mediterranean diet has been linked to a number of other health benefits, including a lower risk of Alzheimer’s and Parkinson’s disease, certain types of cancer, and heart disease, according to Mayo Clinic. “Chronic yo-yo dieting appears to increase abdominal fat accumulation and diabetes risk,” notes Clark. Sticking with such a restrictive diet long-term can be difficult, however, and leave you open to weight re-gain, and the cycle of yo-yo dieting. For example, research highlights the importance of whole grains for controlling weight as well as episodes of high blood sugar. Carbohydrates help control blood sugar levels, which are of particular importance for people with diabetes. Consequently, individuals following low-carbohydrate diets are susceptible to serious nutritional deficiencies 32,33. By modifying glutamate and GABA levels, the diet plays a key role in its antiepileptic effects. When following a KD, the body shifts to burning fat for energy when carbohydrates are restricted. In particular, the KD alters metabolism to promote higher levels of lipid oxidation along with liver ketogenesis, leading to a decrease in liver fat 10,11,12. As research continues to emerge, we can expect to see new developments and advancements in the use of keto gummies for diabetes management. One trial found no significant difference between the fasting-onset and gradual onset ketogenic diet of seizure freedom, and a greater seizure reduction rate was found in the gradual-onset ketogenic diet group. Martin-McGill et al. published an updated Cochrane review on the evidence for ketogenic diet anti-seizure activity from randomized clinical trials. Patients treated with a ketogenic diet, however, had a significantly higher result in gastrointestinal symptoms . REPORTED CONTRAINDICATIONS TO THE KETOGENIC DIET The quantification of total and free cholesterol in the liver also demonstrated that a ketogenic diet increased the amount of cholesterol in the liver (Figure 6B). The results showed that both cholesterol and LDLC quantity in serum were higher in the ketogenic diet-fed fibrotic mouse group compared with the CCl4- or TAA-alone groups (Figure 6A). Surprisingly, when we examined the result of H&E staining again, we found that the ketogenic diet-supplemented fibrotic mouse group possessed more lipid accumulation in the liver tissue (Figure 1E and Figure 2E). These data demonstrate that the ketogenic diet increased the severity of both CCl4- and TAA-induced liver fibrosis. When it comes to Kelly Clarkson’s weight loss, her diet played a crucial role in helping her achieve her goals.By addressing the emotional factors that had contributed to her weight gain, Clarkson found the strength to stay on track.It just means we need larger, better studies on the topic.This will, of course, make the whole diet easier to stick to.Of these, 37 patients who had been on a ketogenic diet for at least three months and had imaging results to assess malignant tumor progression were included in the analysis.There are many variations of carbohydrate limited or restricted diets, ranging from moderate to very low carbohydrate diets, and a strict definition remains to be agreed; however, Feinman provided the most commonly used categories of carbohydrate-focused diets.“I had to learn how to love my body at every size,” Clarkson explained in an interview. The clinical trial, involving 609 overweight adults, did not demonstrate any results of statistical significance regarding its primary outcome measure, which was weight change with an HLF diet or HLC diet over 12 months. The term “Ketogenic Diet” may lead to apprehension in diabetic patients given its association with the well-known, life-threatening condition of ketoacidosis. A crossover study by Gower et al. included participants with PCOS who were randomly assigned to either a standard diet or an LCD. Mild ketosis is a natural phenomenon that occurs in humans during fasting and lactation (19,20). Mushroom gummies are a growing trend, with potential to support health in several ways. Clinical studies support the nootropic effects of lion’s mane. Mushroom gummies are marketed for various health benefits, but which ones are real?