For non-prescription products, read the label or package ingredients carefully. It is also used as a soaking solution to relieve minor sprains, bruises, muscle aches or discomfort, joint stiffness or soreness, and tired feet. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Other side effects not listed may also occur in some patients. Some side effects may occur that usually do not need medical attention. It is very important that your doctor check your and your child's progress at regular visits to make sure this medicine is working properly.A small tube with a camera is guided into the colon.Depending on your symptoms, your health care professional may order X-ray imaging.Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you think this medicine is not working properly after you have taken it for several weeks, check with your doctor first and do not increase the dose.It is best if you do not eat any solid food before taking this medicine and until after your colonoscopy.If those changes don't help, other treatments may be necessary.Exercising or working hard, especially in heat, can lead to muscle cramps.Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ColPrep Kit® or Suprep Bowel Prep Kit® in the elderly. Do not drink anything at least 2 hours before the colonoscopy. Do not take any medicine by mouth within 1 hour before using citric acid, magnesium oxide, and sodium picosulfate combination. Avoid taking other laxatives while you are taking this medicine. This medicine comes with a Medication Guide and patient instructions. Some medicines and illnesses also might cause muscle cramps. This includes prescription or non-prescription (over-the-counter OTC) medicines and herbal or vitamin supplements. It is very important that your doctor check your or your child's progress at regular visits to make sure the medicine is working properly and to check for any unwanted effects. Remain on your bed after taking the first and second doses of this medicine. This medicine can be taken as a single dose (for idiopathic hypersomnia) or divided into 2 nightly doses. It is very important that your doctor check your and your child's progress at regular visits to make sure this medicine is working properly. Appropriate studies have not been performed on the relationship of age to the effects of pantoprazole to treat erosive esophagitis in children younger than 5 years of age. Do not take other medicines unless they have been discussed with your doctor. Our caring team of Mayo Clinic experts can help you with your constipation-related health concerns. An X-ray can show where stool is present in the colon and if the colon is blocked. Before this procedure, you may have a limited diet, use an enema or drink solutions that clean out your colon. This can reveal the condition of the colon or the presence of irregular tissues. Take the second dose 2 1/2 to 4 hours after you take the first dose. Store the second dose close to your bed in a child, out of the reach of children. This medicine can make you sleep very quickly (within 5 to 15 minutes) without feeling drowsy. The first nightly dose should be taken at least 2 hours after you eat. Tests of the rectum and anus Using this medicine with any of the following medicines is not recommended. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Appropriate studies have not been performed on the relationship of age to the effects of Clenpiq® and Prepopik® in children younger than 9 years of age. This medicine is available only with your doctor's prescription. Call your doctor for medical advice about side effects. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Take this medicine exactly as directed by your doctor. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. You'll likely first see your doctor or other general health care professional. Your health care professional may use one of these if the rectum is blocked with stool. Laxatives are medicines that help move stool through the colon. Keep yourself hydrated before, during, and after using this medicine. Do not take any medicine by mouth within 1 hour before taking this medicine. Avoid taking other laxatives (eg, bisacodyl, sodium picosulfate) while you are taking this medicine. If you have not received such instructions, or if you do not understand them, check with your doctor in advance. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements. Fainting may occur during treatment with this medicine, which may increase risk of falls, head injuries, and fractures. It is important that your doctor check your or your child's progress closely for any problems or unwanted effects that may be caused by this medicine. Cleaning your colon will help your doctor see inside of it more clearly during colonoscopy. It works by causing you to have diarrhea to clean your colon. Citric acid, magnesium oxide, and sodium picosulfate combination is used to cleanse the colon (bowel) in preparation for a procedure called colonoscopy. You may report side effects to the FDA at FDA-1088. Sodium sulfate, potassium sulfate, and magnesium sulfate (oral route) This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. Do not use more of this medicine or take it more often than your doctor tells you to. People who are addicted to drugs might want to steal this medicine. Keep your unused medicine in a safe and secure place. Muscle cramp If you miss a dose of this medicine, take it as soon as possible. Do not eat solid foods or drink alcohol, dairy, drinks, juices with pulp, soy milk, or any drinks, gelatin, or other liquids that are red or purple a day before your colonoscopy. Your doctor will tell you how to take this medicine depending on your colonoscopy schedule, distance traveled, and other personal circumstances. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. It is best to take the medicine only at bedtime or when you are ready to fall asleep. Appropriate studies on the relationship of age to the effects of sodium oxybate have not been performed in the geriatric population. This medicine may cause serious bowel problems (eg, colon ulcers, ischemic colitis). This medicine may cause serious allergic reactions, including anaphylaxis and angioedema, which can be life-threatening and require immediate medical attention. This is more likely if you are receiving this medicine for more than 1 year. Check with your doctor right away if you have convulsions (seizures), fast, racing, or uneven heartbeat, muscle spasms (tetany), tremors, or unusual tiredness or weakness. This medicine may cause hypomagnesemia (low magnesium in the blood). Pantoprazole may increase your risk of having fractures of the hip, wrist, and spine. Take this medicine only as directed by your doctor. Rosuvastatin belongs to a group of medicines called HMG-CoA reductase inhibitors, or statins. It may also be used to reduce the risk of death, heart attack, stroke, or other blood vessel problems in patients with risk factors for heart problems. Muscle cramps occur mostly in leg muscles, most often in the calf. Sometimes called a charley horse, a muscle cramp can be very painful. Some are also available without prescription.This medicine is available only under a restricted distribution program called Xywav® and Xyrem® REMS (Risk Evaluation and Mitigation Strategy) Program.This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more.Foods high in iron include lean meat and seafood, nuts, beans, vegetables, and grains that have iron added to them.Appropriate studies have not been performed on the relationship of age to the effects of Clenpiq® and Prepopik® in children younger than 9 years of age.If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices.This medicine is available without a prescription. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of ColPrep Kit® or Suprep Bowel Prep Kit® in the elderly. Cleaning your colon will help your doctor see the inside of your colon more clearly during colonoscopy or other procedures. Make sure any doctor or dentist who treats you knows that you are using this medicine. Breastfeeding In these cases, your doctor may want to change the dose, or other precautions may be necessary. No information is available on the relationship of age to the effects of magnesium sulfate in geriatric patients. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. It is important that your doctor check you closely for any problems that may be caused by this medicine. Do not eat solid food or drink milk or alcohol while you are using this medicine. You may drink clear liquids (eg, water, apple juice, broth, tea, gelatin without fruit), before, during, and up until 2 hours before the time of your colonoscopy. Appropriate studies have not been performed on the relationship of age to the effects of ColPrep Kit® in the pediatric population. Appropriate studies have not been performed on the relationship of age to the effects of Suprep Bowel Prep Kit® in children younger than 12 years of age. The dose of this medicine will be different for different patients. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. Treatment for constipation usually begins with diet and lifestyle changes meant to increase the speed at which stool moves through the colon. And don't take a calcium supplement at the same time as a meal that's high in iron. For people who take calcium supplements and multivitamins, it's best to take them at different times of day. These could be symptoms of a serious muscle problem called rhabdomyolysis, which can cause kidney problems. Call your doctor right away if you have dark urine, fever, muscle cramps or spasms, muscle pain or stiffness, or unusual tiredness or weakness. These may be symptoms of serious muscle problems, such as myopathy or immune-mediated necrotizing myopathy (IMNM). Imaging tests Rosuvastatin belongs to a group of medicines called HMG-CoA reductase inhibitors, or statins.If your symptoms do not improve within a few days or if they become worse, check with your doctor.Using alcohol or tobacco with certain medicines may also cause interactions to occur.Cutaneous or systemic lupus erythematosus may occur or get worse in patients receiving a PPI.If your dose is different, do not change it unless your doctor tells you to do so.This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements.In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This medicine is available without a prescription. Explore Mayo Clinic studies testing new treatments, interventions and tests as a means to prevent, detect, treat or manage this condition. Although not all of these side effects may occur, if they do occur they may need medical attention. Ask your healthcare professional how you should dispose of any medicine you do not use. The following information includes only the average doses of this medicine. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals.You'll likely first see your doctor or other general health care professional.This medicine may cause hypomagnesemia (low magnesium in the blood).This can reveal the condition of the colon or the presence of irregular tissues.This medicine may also be used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid.Also, this medicine works best if there is a constant amount in the blood.Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. These side effects may go away during treatment as your body adjusts to the medicine. Along with its needed effects, a medicine may cause some unwanted effects. If your dose is different, do not change it unless your doctor tells you to do so. If you are using this medicine without a prescription, follow the instructions on the package. The presence of other medical problems may affect the use of this medicine. This medicine may cause serious stomach or bowel problems (eg, colon ulcers, ischemic colitis). This is more likely to occur if you take medicine for depression, if you are withdrawing from alcohol or benzodiazepine use, or if you have low sodium level in the blood (hyponatremia). This medicine may increase your risk for seizures. Blood and urine tests may be needed to check for unwanted effects. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Rosuvastatin may help prevent or slow down medical problems, like atherosclerosis (hardening of the arteries), that are caused by fats clogging the blood vessels. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. Self-care measures can treat most muscle cramps. Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). Doing so may increase the risk for serious unwanted effects. Do not use extra medicine to make up for a missed dose. If you miss the second dose, skip that dose and do not take any more medicine until the next night. Depending on your symptoms, your health care professional may order X-ray imaging. Your health care professional may order a procedure called an endoscopy. Your health care professional may send samples of your blood to a lab to test for diseases or conditions that can cause constipation. However, do not take 2 doses of this medicine within 12 hours of each other. Sodium sulfate, potassium sulfate, and magnesium sulfate combination is used to cleanse the colon (bowel) before certain medical tests (eg, colonoscopy). You may need to stop using this medicine several days before you have medical tests. Do not stop taking this medicine without first checking with your doctor, or unless told to do so by your doctor. This medicine may increase your risk for fundic gland polyps (abnormal tissue growth in the upper part of your stomach). Serious stomach conditions may occur while taking this medicine. Other Interactions Your doctor may decide not to treat you with this medication or change some of the other medicines you take. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. If you notice any other effects, check with your healthcare professional. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. A small tube with a camera is guided into the colon. For other people, one or more additional tests may be needed to help the health care team understand the nature or cause of constipation. You'll also be asked questions about your medical history, diet, exercise habits and stools. Foods high in iron include lean meat and seafood, nuts, beans, vegetables, and grains that have iron added to them. If you have any questions about the best time to take calcium supplements, ask your pharmacist or a member of your health care team. You may need to stop using this medicine if you have a major surgery, major injury, or if you develop other serious health problems. In addition to this medicine, your doctor may change your diet to one that is low in fat, sugar, and cholesterol. It is against the law and dangerous for anyone else to use your medicine. Also, do not drink alcohol while you are using this medicine. Do not use this medicine if you are also taking another sedative or hypnotic medicine (eg, Ambien®, Phenergan®, Seconal®). Pour any unused medicine down the sink drain after 24 hours. Use the medicine within 24 hours after it has been mixed with water. If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule. You may need to set an alarm clock to wake you up so you can take the second dose on time. Measure your dose with the marked plastic syringe that comes with the medicine. If you think this medicine is not working properly after you have taken it for several weeks, check with your doctor first and do not increase the dose. It is best if you do not eat any solid food before taking this medicine and until after your colonoscopy. This includes prescription (eg, atazanavir, nelfinavir, Reyataz®, Viracept®) or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements. This is more likely if you are 50 years of age and older, if you receive high doses of this medicine, or use it for one year or more. Using these medicines together may cause unwanted side effects. Also, your health care professional may change the medicines you take if they may be causing or worsening constipation. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Your health care professional may prescribe other medicines if other treatments don't work. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Sodium sulfate, potassium sulfate, and magnesium sulfate combination is used to cleanse the colon (bowel) before certain medical tests (eg, colonoscopy).Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pantoprazole in the elderly.Muscle cramps occur mostly in leg muscles, most often in the calf.Other side effects not listed may also occur in some patients.Fainting may occur during treatment with this medicine, which may increase risk of falls, head injuries, and fractures. Taking this medicine for a long time may make it harder for your and your child's body to absorb vitamin B12. Cutaneous or systemic lupus erythematosus may occur or get worse in patients receiving a PPI. Do not use pantoprazole together with medicines containing rilpivirine (eg, Complera®, Edurant®, Odefsey®). Blood, urine, and other laboratory tests may be needed to check for unwanted effects. Get the Mayo Clinic app Using this medicine with any of the following is not recommended. This medicine is available only under a restricted distribution program called Xywav® and Xyrem® REMS (Risk Evaluation and Mitigation Strategy) Program. This medicine is also used to treat idiopathic hypersomnia (IH). This medicine may cause unusual behavior while you are sleeping.Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases.Your doctor may decide not to treat you with this medication or change some of the other medicines you take.These cues help train you to control the muscles needed to pass stool.Citric acid, magnesium oxide, and sodium picosulfate combination is used to cleanse the colon (bowel) in preparation for a procedure called colonoscopy.Check with your doctor before using this medicine with alcohol or other medicines that affect the central nervous system (CNS). Drug Interactions Using alcohol or tobacco with certain medicines may also cause interactions to occur. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter OTC) medicine. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Your health care professional may order a test that tracks the movement of stool through the colon. To help keep this amount constant, do not miss any doses and take the medicine at the same time each day. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. A suppository is a small tube-shaped object placed in the rectum to deliver a medicine. Some are also available without prescription. Prunes are a good source of fiber, but they also have naturally present agents that draw fluids into the colon. If those changes don't help, other treatments may be necessary. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of pantoprazole in the elderly. This medicine may also be used to treat Zollinger-Ellison syndrome, a condition where the stomach produces too much acid. Contact your doctor right away if you have any changes to your heart rhythm. Risk factors If your symptoms do not improve within a few days or if they become worse, check with your doctor. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The amount of medicine that you take depends on the strength of the medicine. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered. Use this medicine only as directed by your doctor. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have unusual tiredness or a fever. If you think you have become pregnant while using the medicine, tell your doctor right away. Using this medicine while you are pregnant can harm your unborn baby. It is very important that your doctor check your progress at regular visits. This medicine comes with a patient information leaflet. Exercising or working hard, especially in heat, can lead to muscle cramps. A muscle cramp is a sudden, unexpected tightening of one or more muscles. This medicine may cause unusual behavior while you are sleeping. If you or your caregiver notice any of these side effects, tell your doctor right away. Your in-depth digestive health guide will be in your inbox shortly. Surgery may be necessary to correct damage or irregularities in the tissues or nerves of the colon or rectum. These cues help train you to control the muscles needed to pass stool. The suppository melts at body temperature and releases the medicine. Also, this medicine works best if there is a constant amount in the blood. Do not use more of it, do not use it more often, or do not use it for a longer time than your doctor ordered. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of rosuvastatin in the elderly.