A substantial body of research has emerged over recent years, focusing specifically on medical cannabis and its potential for alleviating chronic back pain. Engaging with healthcare professionals who are knowledgeable about medical cannabis will ensure that recommendations align with your unique needs. A 2022 study published in the Journal of Pain Research found that many participants reported significant reductions in their pain levels after using CBD-based treatments. The evolving landscape of cannabis therapy is revealing not just relief from pain but enhancements in overall quality of life. Many individuals grappling with chronic discomfort seek alternatives to traditional pain management methods, and medical cannabis has emerged as a viable option. The cross-overperiod was followed by a 16 week medication switch period with free choice, inwhich the number of study participants who favored nabilone was over four timeshigher than those who were assigned the placebo. Additionally, there was a statisticallynon-significant decrease in the average spinal pain intensity and improvement inreported quality-of-life over the final 4 weeks of the study. The first, a Germain-language cross-over RCTperformed in Austria, investigated the efficacy in adding Nabilone to a baselinepain medication regimen for treating chronic back pain.21 In this study, the baseline medication consisted of opioids andantirheumatic agents. We found no studies meeting our inclusion criteria that assessed the effect ofcannabis in managing pain following spinal surgery. Included were all concurrent comparativestudies (randomized and nonrandomized) comparing medical cannabinoid use, anydose, and any administration to any non-cannabinoid treatment. None of the participants in the THC/CBD group reported adverse events of the nervous system. We present a qualitative analysis of the study results (Langford 2013; Toth 2012) because the data were not suited for quantitative analysis. The analysis was not possible because fatigue was assessed only by one study (Langford 2013). Two studies were of high risk of bias because they did not report all predefined outcomes (Ellis 2009; Selvarajah 2010). Due to the limited number of studies on this topic, all types of studies that met the inclusion criteria were included. Cannabidiol and tetrahydrocannabinol are the most researched components of cannabis, the plant more commonly known as marijuana or hemp. This makes it necessary to search for new painkillers. However, if you’re concerned about THC exposure, travel frequently, or are new to CBD, isolate-based gummies are a great entry point. Anxiety Relief They found nostatistically significant advantage of using dronabinol compared todiphenhydramine for relieving chronic neuropathic pain related to SCI. Change in pain intensity using the BriefPain Inventory (BPI) scale was the primary outcome of the study. Despite thehigh attrition rate, there was a statistically significant decrease in reportedspinal pain intensity at the end of the study in both the intent-to-treat andthe per-protocol analysis. A total of 30 patients participated in this trial.Participants were randomized and received either Nabilone (.25 mg) or a placebo(mannitol 270 mg). Three of these studies wereconducted in the United States22-24 and one in Austria.21 The average age of the participants was 45 years. "Anecdotally, people say cannabis works great," says Price, an assistant professor of neurological surgery at UC Davis. It's a question spine surgeon Richard Price says he gets at least several times a day from patients who come into his clinic. Now new studies from Europe show it may be an effective option. Chronic pain affects between 50 and 116 million American adults, a staggering number that surpasses those affected by heart disease, cancer, and diabetes combined (Committee on Advancing Pain Research Care and Education, 2011; Nahin, 2015; NIH, 2020). In this mini-review we will evaluate literature discussing CBD use in treating intractable pain and the potential hazards of its overuse and/or misuse (see Figure 1). With the recent rescheduling (Schedule V) of CBD as Epidiolex for the treatment of Dravet and Lennox-Gastaut syndromes there has been a major shift in the view of these ancient molecules for their medicinal potential (Laux et al., 2019). As well, CBD use by pregnant women is rising and poses a major health-hazard for future generations. Dosing Tips for Effective Pain Relief These gummies come with a moderate concentration of THC and deliver gentle relief from pain and tension. Each gummy contains a potent dose of 25mg CBD and 5mg THC for both relaxation and pain relief. THC gummies contain the same psychoactive compound as other cannabis products. Cannabis‐based medicines for chronic neuropathic pain in adults. The word “cannabis” can be used to describe any products made from the plant. One increasingly popular strategy for sleeping better is taking cannabidiol (CBD), a derivative of cannabis. A good night’s sleep is essential to your overall health and wellbeing. Singh’s research and clinical practice focuses on sleep disorders, including excessive daytime sleepiness, narcolepsy, sleep apnea, chronic snoring, insomnia, and sleep education. They use different descriptors for their pain (e.g. burning, tugging, pricking, cramping). In addition, there are issues about the time needed (if any) for washout between treatment periods. The short study duration limits their applicability. We found three industry‐sponsored studies of THC/CBD spray with negative results, which have not been fully published yet. According to the predefined categories there was no clinically relevant harm by cannabis‐based medicines (see Analysis 1.3).You’ll find CBD in all kinds of forms, like oils, gummies, creams, and vapes, making it easy to find one that fits your lifestyle.FOCL uses just the right amount of CBD and micro-doses of THC to make a difference in your health.After carefully analyzing the thriving CBD market, the FOCL Feel Good Gummies stand out as the top recommendation for those looking to manage pain and inflammation effectively.The authors feel it is unlikely that 70% of patients with arthritis in the general population have tried CBD.Similarly, patients taking CBD for a period of more than three years were 3.6 times more likely to reduce or cease other medications, when compared to those taking CBD for less than 30 days. Always choose gummies made from high-quality, organically sourced hemp. This combined benefit makes CBD gummies a versatile option for those managing pain and anxiety together. CBD gummies for pain are edible treats infused with cannabidiol (CBD) designed to help manage discomfort. Regardless of these strengths, these gummies contain only 3 mg THC per serving, which relieves minor aches and discomfort without the psychoactive side effects. These pain management CBD gummies are available in cherry flavor with a light sugar dusting that adds a nice texture without tipping into sweetness overload. While more research is needed, many people report relief from headache symptoms with cannabidiol CBD, especially when used alongside traditional treatments. Athletes and active individuals often turn to cannabidiol CBD for its ability to alleviate delayed onset muscle soreness (DOMS) without the side effects of over-the-counter pain relievers. A 2018 review published in Frontiers in Pharmacology highlighted CBD’s ability to ease inflammation and nerve pain, all without the side effects you’d expect from traditional painkillers . Your body has something called the endocannabinoid system (ECS), which helps keep things like mood, sleep, and pain in check. Inhalable products like flower and pre-rolls deliver immediate relief and full-spectrum cannabinoid benefits. Curio’s tablets are engineered for consistency and precision, which may appeal to patients managing complex pain conditions or looking for non-smoking options. Whether you’re dealing with chronic soreness or post-workout stiffness, Pain makes it easy to apply relief exactly where you need it. We recommend consulting with a clinician before combining cannabis (which includes CBD hemp products!) with pharmaceuticals or over-the-counter pain medications. If you’re considering incorporating cannabis for back pain, joint stiffness, or other chronic issues into your wellness routine, check out the options available from Curio Wellness. For example, a 2022 article in the Global Spine Journal reported significant improvements in back pain symptoms in patients using cannabis as part of their care plan. Made with premium live rosin, this vape preserves the natural cannabinoids and terpenes of the Cannablitz strain, offering a rich experience that may support pain relief, relaxation, and overall balance. Available as flower or pre-rolls, Curio’s best cannabis strains for pain provide a flavorful, smooth smoke and fast-acting potential—ideal for moments when quick, effective relief is needed. One study excluded people who had used marijuana in the month before study entry (Schimrigk 2017).The use of topical NSAIDs has also been studied as an alternative to oral NSAIDs, due to the unwanted systemic side effects of the latter.CBD isn’t just for temporary relief—it can also support long-term pain management.Estimates of incidence vary between individual studies for particular origins of neuropathic pain, often because of small numbers of cases.However, THC can have unwanted side effects such as disconnected thoughts, panic attacks, altered perception, delusions, and hallucinatory experiences .While gummies may not be considered the best consumption method for anxiety, they can still be used to help manage anxiety levels.FOCL Feel Good Gummies are an all-around choice that can help with everything from pain to just making your day a bit brighter.Known for their potent, flavorful gummies and reliable effects, TREHouse offers a wide variety of THC products that are third-party tested and formulated for consistency. Study: Medical Cannabis And Driving Among Australian Patients In particular, we included key information concerning the quality of evidence, the magnitude of effect of the interventions examined, and the sum of available data on the outcomes. In circumstances where there were no data reported for an outcome, we planned to report the level of evidence as very low quality (Guyatt 2013b). We used the GRADE system to rank the quality of the evidence using the GRADEpro Guideline Development Tool software (GRADEpro GDT 2015), and the guidelines provided in Chapter 12.2 of the CochraneHandbook for Systematic Reviews of Interventions (Schünemann 2011). We used a random‐effects model using the inverse variance method in Review Manager 5 for meta‐analysis (RevMan 2014) because there was significant clinical heterogeneity due to the different types of neuropathic pain conditions included. Since CBD was made federally legal in 2018, studies and user feedback have indicated that the substance can help a range of issues from insomnia to anxiety — and even chronic pain.Even though some people use THC for medicine, the FDA has still not approved all forms of marijuana for medical use.The effect sizes of mean pain intensity, sleep problems and psychological distress were clinically relevant.Always check your state laws for THC products.We combined different neuropathic pain conditions in analyses for exploratory purposes only.This is why more and more people are turning to natural alternatives like THC gummies to meet their pain management needs.Smoked cannabis can have bioavailability rates as high as 56%, compared with 4% to 20% for orally ingested cannabis. In studies of generalized chronic pain, CBD treatment did not significantly reduce measures of pain, however there was consistent improvement in patient-reported quality of life and quality of sleep (Notcutt et al., 2004; Capano et al., 2020). Since the early 2000s, clinical trials involving CBD for the treatment of chronic pain have shown effects ranging from placebo-equivalent to highly effective; many of these studies have been well-designed randomized, double-blinded, and placebo-controlled. Although there have been some recent therapeutic advances, many patients with chronic pain develop tolerance to conventional medical treatments or suffer adverse effects from widely used prescription medications, such as non-steroidal anti-inflammatory agents or opiates, that have high addictive potential (Labianca et al., 2012). When Price finally dived into the evidence several years ago, he found there were not many high quality studies, even though chronic pain is one of the most common reasons people turn to medical marijuana. THC and CBD products like gummies are preferred for long-term and consistent relief from chronic pain because their effects last longer. Furthermore, most of the reported side effects in our study were mild (84%), which echoes the findings in clinical trials and cross-sectional studies. Another possibility is that healthcare professionals may not be discussing CBD use with their patients. Despite all of the study participants having a diagnosis that was made by a physician, only 45.6% had spoken to a health care professional about CBD use for their condition. Cannabinoids have been shown effective in human trials for chronic pain (Campbell et al., 2018; Moeller-Bertram et al., 2019; Wiese & Wilson-Poe, 2018). Given the severity of the current opioid epidemic, finding alternative treatments for pain is vital to public health (Mattson et al., 2021). For CBD-only medication, there is substantial evidence for stress, moderate evidence for anxiety and insomnia, and minimal evidence for depression and pain. The overall effect of adding CBD to THC medicines is to enhance the analgesic effect but counteract some of the adverse effects. Most negative effects of CBD medications and products are mild. One study showed that nearly 80% of participants who used CBD to treat their anxiety reported lower anxiety levels within a month. While not a sleep disorder itself, anxiety can contribute to poor quality sleep, insufficient sleep, and sleep disorders. We will summarize here conclusions from both animal and human studies on some possible effects of CBD prenatally, perinatally, and postnatally. Thus, there is an unmet need to examine the potential effects of CBD on embryonic and fetal development and the postnatal health of children exposed to CBD before birth. While several studies have focused on THC during pregnancy, investigation focused on the effects of CBD usage by pregnant women before, during, and/or after pregnancy are rare. Alternatively, there is preliminary evidence that CBD may interact with α3-glycine receptors to reduce inflammation and hyperalgesia following simulated neuropathic pain by ligation of the L5 spinal nerve in adult Sprague-Dawley rats (Xiong et al., 2012). An urgent need is to regulate CBD products after reliable testing to prevent the inadvertent harmful effects of unidentified constituents of products labeled CBD. After carefully analyzing the thriving CBD market, the FOCL Feel Good Gummies stand out as the top recommendation for those looking to manage pain and inflammation effectively. If you’re concerned, opt for broad-spectrum or CBD isolate products, which are THC-free and less likely to trigger a positive result. However, full-spectrum CBD products contain trace amounts of THC (less than 0.3%), which might show up on a sensitive test if consumed in large amounts. A general starting dose is between mg per day, which can be adjusted based on your body’s response and the severity of your pain. CBD products may contain higher levels of THC than reported or contain THC that is not reported on the label at all. Unlike THC, CBD does not induce a feeling of being “high.” Even large doses of CBD do not produce THC-like effects. As a result, the amount of CBD in products varies widely among forms. As a result, there has been an influx of hemp-related products in the American market, confusingly marketed as CBD products. While many health benefits have been attributed to CBD, in most cases, scientific validity of its effectiveness is still unclear. THC and CBD combination medicines have a good safety and tolerability profile that is appropriate for opioid stage (stage 2–3) treatment of chronic pain. Low-dose CBD (less than 150 mg/day) that appears effective for chronic pain and mental health conditions has a good tolerability and safety, with few adverse effects (Di Bartolomeo et al. 2021; Iffland and Grotenhermen 2017; Stark et al. 2021). Although, chronic pain is a common reason for self-prescribed CBD-only products (Moltke and Hindocha 2021) and the addition of CBD to THC medicines improves analgesic efficacy (Johnson et al. 2010). In systematic reviews, the overall prevalence of neuropathic pain in the general population is reported to be between 7% and 10% (Van Hecke 2014), and about 7% in a systematic review of studies published since 2000 (Moore 2014a). For postherpetic neuralgia, for example, studies demonstrate a large loss of quality of life and substantial costs (Scott 2006; Van Hoek 2009). Overall, the treatment gains in neuropathic pain, to even the most effective of available drugs, are modest (Finnerup 2015; Moore 2013a), and a robust classification of neuropathic pain is not yet available (Finnerup 2013). One of the best CBD creams for pain relief is this one from TryTheCBD. If you’re looking for a strong CBD for pain relief, check out this cream from CBDfx. We’ve included topical CBD for pain, as well as other products like CBD gummies for pain. Below, we’ve rounded up some of the best CBD for pain relief that you can buy online right now. When seeking the best CBD brands for pain relief, Greller says to look for transparency. Look for products that are third-party lab tested, with accessible lab results verifying potency and purity. Trusted brands often have better quality control and a commitment to safety. Since CBD gummies have a slower onset than some other forms, such as oils, be patient as they take effect, generally within 30 minutes to an hour. Gummies can be taken at any time of day, but many users find it helpful to take them during periods of discomfort or before bedtime if sleep support is needed. There are issues over both random chance effects with small amounts of data, and potential bias in small studies, especially in pain (Dechartes 2013; Dechartres 2014; Moore 1998; Nüesch 2010; Thorlund 2011). Therefore we do not know the efficacy of cannabis‐based medicines for specific qualities of neuropathic pain. No subgroup comparisons (former cannabis users versus cannabis‐naive participants) were conducted by any study. MeSH terms He’s also written third-party lab test reports of CBD products and knows the industry inside and out. He’s read thousands of studies about cannabinoids and other beneficial natural compounds, helping him translate complex science into plain language. Gleb Oleinik is a freelance CBD & cannabis writer from Vancouver, Canada. When it comes to treating pain with cannabis, both the type of product and the ratio of cannabinoids matter. Last week, we overviewed different types of pain and shared how cannabis might help. Relief may not come overnight—but with the right approach and guidance, the best cannabis for pain can become a trusted part of your daily wellness toolkit. Studies suggest that cannabis for back pain may help reduce muscle spasms, ease inflammation, and calm nerve irritation. These are often preferred by patients who need fast-acting results, especially during pain flare-ups. It might be expected that, at best, a few people with neuropathic pain will benefit from long‐term use of cannabis‐based medicines. Andreae 2015 performed an individual participant data analysis of 178 participants from five studies of inhaled cannabis. The absence of publication bias (unpublished trials showing no benefit of cannabis‐based medicines over placebo) can never be proved. In this review, we chose to limit analyses to studies with a minimum of 10 participants per treatment group. On the other hand, it may be unethical to ignore potentially important information from small studies or to randomise more participants if a meta‐analysis including small, existing studies provided conclusive evidence. As we continue on this journey, we’ll further explore how medical cannabis can provide unique advantages for those experiencing discomfort in their muscles and joints. This dual action allows cannabis not only to lessen the immediate perception of pain but also to address underlying issues such as inflammation that can perpetuate discomfort. The subsequent action comes from pain modulation, which is crucial for individuals dealing with chronic conditions or acute injuries. With CB1 receptors primarily located in the brain, THC binds directly here to produce its psychoactive effects while modulating pain signals. Studies have shown that CBD can help with chronic pain, arthritis, neuropathy, and even migraines.This can be beneficial if you’re using CBD for sleep-related issues or nighttime pain relief.All studies compared cannabis‐based medicines with placebo except one study that compared synthetic THC with dihydrocodeine (DHC).In all articles, cannabis was shown to be effective to treat back pain withan acceptable side effect profile.These gummies are further lab-tested for safety and quality assurance.THC and CBD combination medicines have a good safety and tolerability profile that is appropriate for opioid stage (stage 2–3) treatment of chronic pain. We’ve thoroughly reviewed each option, covering their pros and cons to help you decide which one may be the best fit for your pain relief needs. They’re great for target-specific pain relief, calming sore muscles, or even easing joint pain without leaving that medicinal aftertaste. An early double-blind RCT found that 160 mg CBD in participants suffering from insomnia improved their duration of sleep significantly better than placebo and was non-inferior to 5 mg nitrazepam (Carlini and Cunha 1981). Cannabis-Infused Eggnog: A Cozy, Low-Dose Holiday Classic THC is known to help with various kinds of pain, including neuropathic pain, arthritis, fibromyalgia, and other inflammatory conditions, by blocking pain signals and managing inflammation.As people search for natural, non-addictive solutions, CBD gummies…Previous cross-sectional analyses have found at least one reported side effect in 29–59% of patients using CBD for different indications which is in concordance with our findings (41%) (Corroon & Phillips, 2018; Devitt, 2019; Moltke & Hindocha, 2021).Whether it’s pain from conditions like fibromyalgia or general long-term discomfort, CBD offers a non-intoxicating option to help you feel more like yourself.These effects are in line with reports of hormonal and reproductive effects due to postnatal exposure to CBD or cannabis in rats and monkeys.CBD, in general, has been shown to help ease muscular pain and gummies are no exception.We post hoc decided to perform subgroup analyses of studies with and without publication in peer‐reviewed journals and of studies with high and unclear sample size bias. These THC gummies are built for deep sleep, heavy relaxation, and serious stress relief. To address these gaps, further studies are needed that assess both the therapeutic benefits and potential adverse effects of cannabis. Additionally, there is a scarcity of studies, particularly RCTs, comparing the efficacy of cannabis to other active analgesic treatments. Cannabis is gaining attention as a potential alternative or complementary treatment to opioids, with preclinical studies suggesting opiate-sparing effects. Just throw it in the bag and apply it whenever you feel like the pain is creeping up. Plus, it features 100% clean ingredients, so you’re getting the purest form of relief. By focusing on full-spectrum formulations and maintaining rigorous quality control, they offer pet owners a trustworthy option for natural pet wellness. To address these gaps, further studies are needed that assess both the therapeutic benefits and potential adverse effects of cannabis.Trusted in Maria’s kitchen, the LEVO Lux makes it effortless to infuse oils or butters with cannabis for perfectly dosed THC or CBD gummies.A 2018 review published in Frontiers in Pharmacology highlighted CBD’s ability to ease inflammation and nerve pain, all without the side effects you’d expect from traditional painkillers .Cannabis, also called marijuana, is widely used as a sleep aid, both recreationally and among medical users.If appropriate we will update the review before this date if new evidence likely to change the conclusions is published, or if standards change substantially which necessitates major revisions.These fast-acting CBD sleep gummies work best at the end of a long day when you’re ready to unwind and recover.But modern cannabis is much different than it was hundreds of years ago.Each gummy comes with 25mg of CBD and 2mg of THC, making it a mild yet effective option for pain relief.For some of us, it’s our sleep that’s most affected (which can inevitably lead to an assortment of different problems). Compared to THC, CBD does not have psychoactive properties and does not have effects that would lead to potential dependency or risk of abuse. Proper sleep contributes to memory formation, prevents sickness, and ensures you feel well-rested and have energy for the next day. Experts recommend adults sleep at least seven hours each night. “Pain intensity following edible cannabis use decreased over time across all three broadly defined product groups,” investigators reported. Effects can vary between batches, especially if you're using a DIY THC gummies formula or skipping ingredients like lecithin. For most users, effects last 4 to 8 hours, but higher doses can linger longer—especially for low-tolerance individuals or recipes made with high-potency concentrates. Creating perfect, potent weed gummies takes patience, precision, and a few pro tricks. This method often produces fast-acting gummies due to better absorption. Made with natural colors and flavors, these ready-to-use mixes make it easy to experiment and craft delicious THC or CBD gummies at home. Another cause for concern is the unreliability of the purity and dosage of CBD in products. Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. Food, drinks and beauty products are among the many CBD-infused products available online. Best Brands for CBD Gummies for Pain Many people use cannabis to manage chronic pain symptoms, and there’s a good amount of evidence that it may be an effective treatment option. And in a survey of over 900 people with chronic pain, 75% reported pain relief as the main benefit of their cannabis use. There is no high‐quality evidence suggesting that cannabis‐based medicines (herbal cannabis plant‐derived THC (dronabinol), synthetic THC (nabilone), plant‐derived THC/CBD combination) are of value in treating people with chronic neuropathic pain. Our Sleep Blueberry Chews offer a reliable, plant-powered path to potentially pain-free nights. This makes the cannabinoid-infused chews from Curio Wellness a go-to for people dealing with constant or nighttime pain. Because they’re metabolized by the liver, edibles offer longer-lasting effects– often up to 6–8 hours. Another study showed that opioid use for pain went down by over 60% in those using cannabis for chronic pain. And since it’s not an FDA-approved treatment, it can be hard to know where to start if you’re considering cannabis to help manage your chronic pain symptoms. Since no single treatment is effective in a majority of individuals with chronic neuropathic pain, this relatively small number of people with neuropathic pain who benefit from cannabis‐based medicines may be considered worthwhile, particularly if switching rules are in place. In the absence of high‐quality evidence of benefit, the use of cannabis‐based medicines at the discretion of a pain specialist with particular expertise in use of cannabis‐based medicines is desirable. There is no high‐quality evidence for the efficacy of any cannabis‐based medicine (herbal cannabis, plant‐derived THC (dronabinol), synthetic THC (nabilone), plant‐derived THC/CBD combination) in any condition with chronic neuropathic pain. Different types of CBD and the various modes of administration could have possible varying effects, which we were not able to capture in this investigation. Fourth, patients submitted subjective reports of their symptoms, and the survey was not distributed in a controlled manner immediately after CBD use, making the results susceptible to recall bias. Additionally, because the survey was distributed online through social media posting and patient representative groups, patients with arthritis who have limited connectivity to the internet are potentially underrepresented. The authors feel it is unlikely that 70% of patients with arthritis in the general population have tried CBD. Of the respondents, 176 (30%) patients with arthritis had not tried CBD, whereas 428 (70%) endorsed CBD use. This tincture can positively affect sleep quality, so you can wake up feeling a lot more refreshed. Each product — from its soothing drops to functional gummies — is lab-tested for quality assurance and safety. FOCL is one of the most reputable brands offering premium quality CBD and THC products to boost mood, enhance focus, promote calm, and even improve sexual performance. They are formulated with Full Spectrum+ alongside a beginner-friendly dose of THC, so you’ll get all the goodness of the medical cannabis plant without going overboard. If you’ve tried everything under the sun to manage your pain, CBD products might be a great alternative. CBD Gummies for Kids However, not everyone experiences the same sleep benefits with CBD use, and additional research is needed to deepen our understanding of CBD as an intervention for sleep disorders. Currently, there is insufficient research to determine the effectiveness of CBD in treating other health conditions. So far, CBD’s effectiveness in the treatment of epilepsy is well-supported by research. These pain gummies contain 750 mg of CBD and only 5 mg of THC for feeling nice and light without turning into a couch potato. CBDistillery is one of the best brands that use US-grown hemp extract while manufacturing its cbd gummy products. These gummies also help with those stress knots and racing thoughts that make it hard to sleep. Cannabis‐based medicines may increase nervous system adverse events compared with placebo (61% versus 29%; RD 0.38 (95% CI 0.18 to 0.58); NNTH 3 (95% CI 2 to 6); 1304 participants, nine studies, low‐quality evidence). The overall quality of evidence for the effect of cannabinoid treatment inchronic pain following spinal cord injury was rated as LOW for its immediateeffect (1–3 hours), and VERY LOW for its short-term effect (7 weeks), Supplemental Table S4. However, long-term follow up is lacking.As medicinal cannabis is being used more commonly for analgesic effect andpatients are “self-prescribing” cannabis for back pain, additional studiesare needed for healthcare providers to confidently recommend cannabistherapy for back pain. From mild soreness to chronic pain patients, people across the country are turning to CBD gummies as part of their wellness toolkit. Another study in The Journal of Pain found that cannabidiol CBD not only reduced chronic pain but also helped improve sleep—something anyone dealing with pain can appreciate . Those who are concerned about the effects of smoke on the lungs may prefer to avoid smoking it. Hybrid strains with a mix of indica and sativa may produce different effects based on the specific makeup of cannabinoids and other ingredients. Most of the differences attributed to sativa versus indica strains are based on the subjective experiences of cannabis users. Get the latest health tips and articles delivered directly to your inbox. However, the effectiveness in this population of legal market forms of cannabis, particularly commonly used edibles, is unknown. Our natural relief solutions use premium hemp-extracted CBD alongside other helpful ingredients. Full‑spectrum gummies contain trace THC, which could register on sensitive tests. Third, patients with polarizing views on experiences using cannabinoids—whether they are positive or negative—may be more likely to have participated in the study, which could lead to either positive or negative bias. This higher prevalence may be due to a selection bias secondary to patients who have used CBD being more likely to participate in the study. Two recent studies found a prevalence of CBD use in patients with arthritis to be between 24 and 57% which is lower than our findings (Deckey et al., 2021, Nowell, 2019). These findings suggest that CBD could be an alternative to opioids for the treatment of arthritic pain. Vertanical, the German company that funded the trials, expects to win approval to market their full-spectrum cannabis oil, called VER-01, to patients in several European countries in a matter of months. Because cannabis remains a Schedule 1 drug — a category reserved for substances with no accepted medical use — and is heavily regulated, this type of large-scale clinical trial is tough to pull off in the U.S. The first, published in the journal Nature Medicine, showed that a blend of cannabis oil, containing the psychoactive compound THC, as well as CBD and other natural compounds in the plant, outperformed a placebo. Used consistently, CBD gummies may become a helpful part of a broader pain management strategy. When you take CBD gummies, the cannabidiol interacts with these receptors, supporting a natural sense of relief and recovery. CBD gummies are edible supplements infused with CBD extract, typically sourced from hemp—a type of cannabis that contains less than 0.3% THC. In this guide, you’ll learn how CBD gummies work, how to choose the best CBD gummies, and discover the 3 best CBD gummies for pain in 2025. We used intention‐to‐treat (ITT) analysis where the ITT population consisted of participants who were randomised, took at least one dose of the assigned study medication, and provided at least one post‐baseline assessment. We split the control treatment arm between active treatment arms in a single study if the active treatment arms were not combined for analysis. We defined studies with zero to two unclear or high risks of bias to be high‐quality studies, with three to five unclear or high risks of bias to be moderate‐quality studies, and with six to eight unclear or high risks of bias to be low‐quality studies (Schaefert 2015). CBD has gained attention as a natural option for managing various types of pain. It also prevents enzymes from breaking down your body’s natural pain-fighting cannabinoids, giving them more time to work. For instance, it connects with TRPV1 receptors (sometimes called “vanilloid receptors”), which are directly involved in sensing pain. It doesn’t just mask pain; it helps your body manage it better by targeting inflammation and calming your nervous system. The way CBD is extracted from hemp or cannabis plants makes a big difference in how effective and pure it is. The datasets used and/or analyzed during the current study are available from the corresponding author on reasonable request. Ronnie Sharp (Savvy Coop, Ltd.), Teresa Gaudio, and Nancy Sorbella (The Arthritis Foundation®) for their help in distributing our survey to patients. The present study, while exploratory in nature, suggests there may be therapeutic benefits to CBD use and highlights the need for research in a field where the science lags behind popular use. In states where cannabis has been approved for recreational and/or medical use, there are efforts to equip dispensary staff with scientific knowledge to make evidence-based recommendations, but these efforts are limited and often overshadowed by anecdotal understanding of CBD and other cannabinoids (Haug et al., 2016; Piermarini and Viswanath, 2019). As early as 2003, formulations containing CBD have been used in the clinic to study its efficacy in reducing pain when traditional treatment options have failed. Cannabis and its components are being widely used for chronic pain, especially given the multifaceted and persistent nature of chronic pain in many conditions (Kalant, 2001). Additionally, articles published within Cureus should not be deemed a suitable substitute for the advice of a qualified health care professional. Cannabis has a sizeable negative stigma surrounding it, and the patients open to trying CBD may have been more open to positive changes. Second, because the surveys were long, it could have deterred patients from returning for future visits. The surveys themselves were a limitation of this study for two reasons, the first being that they were exceedingly long, leading to survey fatigue taking minutes to complete. These participants dropping out may have been exacerbated by the lack of financial incentives to complete the surveys. With so many brands and formulas available in the US, it’s not easy to know which CBD gummies are truly worth buying. ” The truth is, the best option depends on your needs—like pain level, lifestyle, and whether you want CBD-only or CBD + THC blends. This system helps regulate functions like pain perception, inflammation, and stress response. We included studies ofadults undergoing spinal surgery (acute pain), those with chronic low back orneck pain (chronic defined as ≥12 weeks), and those with chronic neuropathicpain following a spinal cord injury. It isthe current consensus that adequate pain relief measures are best achieved whenapplying some form of “Enhanced Recovery After Surgery” through a combination ofmulti-modal therapies.2 Unfortunately, most back pain management regimens rely heavily on opioidanalgesics. In each study, there was aquantifiable advantage of cannabis therapy for alleviating back pain. No studies specifically examined theuse of cannabis for surgical back pain. To critically analyze the evidence and efficacy of cannabis to treat surgicaland nonsurgical back pain via a Systematic Review. They may recommend you start with a high-CBD form of cannabis and slowly increase the dose over time. But combining pain medications isn’t something you should do on your own. There are also more serious risks of cannabis use. These side effects can often be avoided by following a dosing schedule that slowly increases your dose over time, such as the one described above.