Research has shown that CBD and THC have a wide range of potential health benefits, many of which are similar. Keep in mind that cannabis laws are always changing and it’s likely to become legal in more states as time goes on. Additionally, medical marijuana is legal in most states. Under this law, hemp and any CBD products derived from it are legal as long as they contain no more than 0.3% THC by weight. More importantly, CBD reduces the breakdown of anandamide, one of the main endocannabinoids produced by the body, and interacts with many other molecules and systems. CBD is a compound that’s extracted from the cannabis plant. What exactly is the difference between CBD oil and hemp oil? (Of course, you should always consult your healthcare professional prior to using CBD and read and follow all label directions.) Currently, the only CBD product approved by the Food and Drug Administration is a prescription oil called Epidiolex. The usual CBD formulation is oil, but CBD is also sold as an extract, a vaporized liquid and an oil-based capsule. However, further research is needed to determine CBD's other benefits and safety. Some medical weed strains help to make you extremely social and outgoing. Indicas and hybrids tend to cause less anxiety and paranoia, but that doesn’t mean you can’t find an amazing sativa strain, because they’re plentiful. Pick the wrong strain and you could actually increase your anxiety. Research shows that cannabis oil may have some benefits.No products shall ever be intended to diagnose, treat or cure any disease or prevent any ailment.Moreover, persistent depersonalization and amotivational syndromes have been observed sometimes in cannabis users .In fact, all cannabinoids are psychoactive, in different ways and to different degrees.CBD, which refers to cannabidiol, is a chemical compound that comes from the cannabis sativa plant.Delve into the benefits of CBD, understand the significance of a life driven by purpose, and discover how transforming your mindset can usher in unparalleled wellness. Tetrahydrocannabinol (THC) is probably the most well-known chemical compound in the cannabis plant. Each of them has unique health benefits, but when used together, they allow you to revel in the full therapeutic potential of cannabis. When shopping for CBD oil online, make sure it comes from hemp unless your country or state allows marijuana for recreational use. THC and CBD can have complementary effects on each other when it comes to their health benefits. When it comes to their use, bot cannabinoids have several recreational and medical benefits. Another area where CBD and THC part ways in the field of medical treatment is in people with psychotic disorders. Sold as Epidiolex, this whole-plant version of CBD is being prescribed to treat rare forms of epilepsy such as Dravet syndrome and Lennox-Gastaut syndrome. It’s so effective, in fact, that pharmaceutical companies have begun purifying and concentrating CBD from marijuana plants. Meanwhile, CBD can counteract these effects from THC – but it also works as an effective anti-anxiety treatment on its own. While some tout THC as being good for their anxiety, the fact is that in many people, THC can cause or worsen feelings of anxiousness. Take THC, for example — it mimics the actions of anandamid, a naturally occurring endocannabinoid, and has been shown to have some positive benefits. CBD has the most documented benefits among other non-intoxicating cannabis compounds, but these other components can combine with CBD for a dynamic combination. A full spectrum product also includes other parts of the plant, including terpenes (which influence the smell and flavor of the extract) and essential oils. Here, an expert breaks down how this important protein promotes healthy digestion.Read More Why Collagen Is So Good For Your Gut Because of the complex connection between these two parts of the body, many skin issues actually start in the gut! Its main topics include nutrition, health, fitness, healthy recipes, home DIY remedies and trending health news. Dr. Hyman is a regular medical contributor to several television shows and networks, including CBS This Morning, Today, Good Morning America, The View, Fox, and CNN. He is the host of one of the leading health podcasts, The Dr. Hyman Show with 150+ million downloads. Synthetic cannabinoids, also known as synthetic marijuana, Spice, or K2, are manufactured chemicals that mimic the high of THC. CBD also comes from the flowering heads of the hemp plant. THC and CBD come from the resin on the leaves and the buds of the female cannabis plants. Cannabis plants with THC concentrations greater than 0.3% are considered marijuana. It’s made from dried cannabis leaves and flowers, or buds, which you smoke or add to foods or drinks. However, since the prohibition in 1937, 16 states have legalized the recreational use of marijuana, and 48 states have some medical marijuana programs for patients. You can buy hemp-derived CBD products all over the U.S., from pharmacies to specialty stores, vape shops, and wellness centers. The side effects of THC include short-term memory impairment, confusion, dizziness, and mental discomforts such as feelings of anxiety and paranoid thinking patterns. THC intensifies this sensation by inserting itself into this natural euphoria pathway. When you consume THC, it binds to your brain’s and central nervous system’s cannabinoid receptors to produce a euphoric effect. All marijuana varieties contain THC — however, some are more dominant in THC while others contain very little. When you first begin using CBD, it could overwhelm you when you’re trying to figure out what products are out there and how you should take them. Some studies show consuming THC — especially smoking it — may result in short-term memory loss and problems thinking. Some people report experiencing dizziness, nausea and headaches, but these are only temporary. Most strains cause red and dry eyes and dry mouth, both of which are managed easily. Edibles have longer-lasting effects but take longer to kick in. Patients should also consider the form of administration, which can include oils, tinctures, edibles, vaporizers, and topical creams. For example, a combination of both can provide more effective pain management and relief while minimizing the psychoactive effects of THC. Cannabis Oil vs. CBD Oil To the best of our knowledge, there is a lack of material in the literature on the rewarding and addictive effects of CBD exposure during adolescence, as well as on its potential relation to other drugs of abuse. Several preclinical and epidemiological studies suggest that adolescent THC exposure may predispose to the abuse of other illicit drugs (i.e., cocaine, heroin, and amphetamines) in later adulthood, thus promoting drug dependence (the so-called “Gateway Hypothesis”) 125,126,127,128,129,130,131. Therefore, the exposure to THC during adolescence induces changes in neurodevelopmental trajectories, leading to long-lasting effects, such as vulnerability to drug addiction and psychotic episodes . Despite the main targets of CBD being the CBRs, as previously mentioned, in vivo and in vitro preclinical studies indicate that CBD may also act on other receptors/channels (e.g., 5-HT1A, A1, GPR55, PPARγ, TRPV1, and μ and δ opioid receptors) in physiologic conditions 69,74,75,76,77,78. The Cannabis Plant: Source of Medical Cannabis What made this health crisis especially challenging was the diagnosis and prognosis he received.What are the different ways you can use CBD hemp?These plants contain compounds that are “cannabimimetic,” which means that even though they don’t share the same biological structure as cannabinoids, they have similar effects on the body.CBD usually comes from hemp, but it can also come from marijuana plants.Other drugs, such as sleep aids, anti-epilepsy medications and blood thinners, can cause negative interactions.Well, unlike both CBD oil and hemp oil, cannabis oil does contain THC and it has intoxicating effects.CBD (Cannabidiol) and THC (Tetrahydrocannabinol) are both cannabinoids, chemical compounds found in the cannabis plant, specifically Cannabis sativa.CBD has the most documented benefits among other non-intoxicating cannabis compounds, but these other components can combine with CBD for a dynamic combination.Δ9-tetrahydrocannabinol (THC) (green) and cannabidiol (CBD) (blue) activity on cannabinoid and non-cannabinoid receptors. When it comes to CBD vs. THC, there are certainly similarities, but their effects can be very different. CBD and THC are the two main active compounds in cannabis. To separate the highest quality products from the rest, look for one that has a certificate of analysis, or COA. It becomes crucial for potential consumers to consider their individual tolerance levels with CBD, as effects can be highly subjective and dependent on many factors, including body weight, metabolism, and the severity of the symptoms being treated.CBD and THC are two different cannabinoids from cannabis, each with its own properties and medical uses.With a focus on natural ingredients and user experiences highlighting a wide range of effects, these gummies warrant consideration for anyone seeking a dietary supplement for anxiety, pain relief, or sleep enhancement.It appears that CBD oil has few adverse side effects when it’s used in appropriate amounts.Many states allow marijuana either for medical or recreational use.My problem is helping you understand there’s a difference between CBD and THC without getting into the hemp claims.Research has shown that CBD may have a range of therapeutic benefits, including reducing inflammation, relieving pain, and promoting relaxation.The Axe family enjoys making healthy gourmet meals like homemade gluten-free pizza, paddle boarding, doing ginger shots, Burst training, and going hiking with their dogs Oakley and Flash. Comparing Dr. Axe’s Approach Before and After His Health Crisis The evolution of Dr. Axe’s messaging from primarily physical health to a more integrated approach that includes mental, emotional, and spiritual dimensions represents a significant shift in the natural health community. Despite these criticisms, Dr. Axe has maintained his commitment to natural approaches to health, often pointing to his own recovery from severe health challenges as evidence of their efficacy. Dr. Axe has also faced criticism for advocating for concepts like “leaky gut syndrome,” which some critics note “is not a recognized medical condition and is only found in alternative medicine literature”. He encourages people facing health challenges to “press into God,” stating that “God is more powerful than all of those things, and you just need to spend time believing and knowing God has what’s best for you.” The question “is Axe Snake Peel discontinued” has been haunting loyal users of this popular exfoliating body wash for years…. He advocates for using natural remedies and shows scientific evidence behind why eating foods like coconut, bone broth, wild-caught fish, fermented vegetables and leafy greens are essential to a healing diet. The show features interviews with health experts, entrepreneurs, and thought leaders. He believes we are all called to love God, love people, and make the earth a heavenly place. All viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. It is not intended to provide medical advice or to take the place of medical advice or treatment from a personal physician. Note that the numbers in parentheses (1, 2, etc.) are clickable links to these studies. CBD oil that comes from the hemp plant typically contains less than 0.3 percent THC. Most CBD oil’s products are made this way and come from what’s referred to as “industrial hemp.” Although the hemp plant contains little or no THC, oils extracted from the resin glands of the plant do contain CBD. Hemp oil (also called hemp seed oil) is extracted from the hemp seeds of the hemp plant and it contains very little or no THC. Hemp and cannabis both come from the Cannabis sativa species, but it’s the amount of THC present in the plant that makes them different. The difference between CBD vs. THC is that the former offers a relaxing sensation to your body without producing a mellow physical high.However, CBD exists in hemp in higher quantities, while THC heavily saturates cannabis.However, it can also reduce pain, increase appetite, assist people with insomnia, and reduce cancer cells throughout the body.During the extraction process, CBD, other cannabinoids, terpenes and flavonoids that are found within the plant are initially extracted.The legal landscape surrounding CBD has also shifted significantly, with various states legalizing cannabis-derived products and fostering a booming market.This is called the entourage effect, which is when the combination of cannabinoids produces a more therapeutic impact than when used alone.One major guideline is to look for full-spectrum Certified USDA Organic CBD oil.The most common CBD oil side effects include drowsiness, dizziness, diarrhea, nausea, vomiting, dry mouth, anxiety and changes in mood. Unlike the antibiotic effect of mouthwash, CBD oil (which is not a mouthwash, but is typically taken by mouth) preserves the integrity of a healthy mouth while still providing benefits. Yes, CBD hemp oil is originally derived from cannabis, but there’s a substantial difference in CBD vs. THC. Common concerns about it can stop some people from enjoying the tremendous natural benefits this compound can provide. Dr. Axe is a certified doctor of natural medicine, a doctor of chiropractic, and a clinical nutritionist with a passion to help people get healthy by empowering them to use nutrition to fuel their health. Dr. Axe’s Health Institute offers programs like the Cellular Health Regenerator program, which aims to provide comprehensive support for those facing health challenges. Throughout his health challenges, Dr. Josh Axe has continued to build his health and wellness business empire, adapting his offerings to incorporate his evolving philosophy. His willingness to share his struggles openly—including moments of despair and hopelessness—makes his message more relatable and provides hope for those facing their own health crises. Dr. Axe’s journey offers a powerful model of resilience in the face of health challenges. His personal testimony of recovery from a severe health crisis that threatened to leave him permanently disabled adds authenticity and depth to his teachings. Although not all people can tolerate THC, some do truly benefit from its effects. CBD causes inhibition of hepatic drug metabolism and a decrease in p-glycoprotein activity in some people. The medical community recognizes CBD as a natural pain reliever. The medical community is only now discovering the huge variety of benefits of CBD. CBD oil is created by extracting CBD from either the cannabis or hemp plant and then diluting it with a carrier oil like coconut or hemp seed oil. Because hemp has greater CBD content than THC, it’s a useful source of CBD for medical marijuana. Your brain’s cannabinoid receptors work with your body’s naturally-occurring endogenous cannabinoids. If your state doesn’t have a legal marijuana market, you can still enjoy the benefits of full-spectrum CBD oil from hemp. As a result, many people mix marijuana with CBD hemp flower to counterweight the intoxicating effects of THC. THC produces the mind-altering, euphoric effects of the plant. While there are similarities between the two cannabinoids, clear distinctions do exist — including how they’re used and the nuances of their psychoactive effects. These grow on the cannabis plant’s flowers and are small, mushroom-like structures. A variety of medical weed strains are made of both cannabinoids so they can complement one another. His writing isn’t just about nutritional facts; it’s about weaving the ancient wisdom of health with modern understanding. They are proof of his dedication to helping us all live the healthiest lives possible, in a natural way. Josh's endeavors, such as AncientNutrition.com, an online nutrition resource, and DrAxe.com, an online haven for natural health, illustrate his mission. Cannabis vs. Hemp This is due to the fact that they interact with different groups of receptors in the brain and throughout the body. Creams and lotions containing THC/CBD can interact with cannabinoid and other receptors located throughout the body. For years, marijuana consumers have used dry herb to create a large menu of THC-infused treats from cannabutter to baked goods such as brownies. However, these effects seem to require large doses and are not well-studied in humans. THC can also cause tiredness, sleepiness, and dry mouth, as well as red eyes and increased heart rate. You’d need to use large doses to experience significant side effects, especially with CBD. However, there’s some evidence that THC may have stronger analgesic (pain-relieving) effects. Meanwhile, CBD is so promising that researchers believe it could help with a wide range of anxiety disorders. Therefore, further studies are required to understand the role of CBD as a potential pharmacotherapy for SUDs in adolescence. Therefore, it is plausible to hypothesize that CBD, through these multiple-receptor mechanisms, normalizes DA transmission altered by drugs of abuse, reducing drug taking, seeking, and relapse 83,119. Indeed, CBD did not affect tobacco withdrawal , but it was able to attenuate opioid subjective-cue-induced craving for up to 7 days after the end of treatment . Hemp is much easier to grow than cannabis, as it requires less water, no pesticides and minimal care — plus it’s adaptable to most climates. Industrial hemp naturally contains very low levels of THC and high levels of CBD. Because of its low THC levels, you can use hemp oil without feeling “high” afterwards. For isolates, purified CBD is extracted from the hemp plant and isolated from other naturally occurring cannabinoids. These plants contain compounds that are “cannabimimetic,” which means that even though they don’t share the same biological structure as cannabinoids, they have similar effects on the body. That’s why more and more research is both needed and is being conducted on CBD oil benefits — exploring the properties of another class of ingredients found in cannabis called cannabinoids. The American Medical Association believed that evidence of cannabis’ harmful effects was limited and the act would prevent further research into its worth health-wise. Most CBD oil comes from industrial hemp, which typically contains more CBD than marijuana. However, it gets confusing because any oil that is CBD-dominant is considered a CBD oil, and it produces different effects from THC-dominant cannabis oils. CBD cannabis oil or CBD hemp oil are both said to be non-psychoactive. Hemp oil — obtained by pressing benefit-rich hemp seeds — is slightly different than cannabis oil, although they both come from the same genus, Cannabis, and the same species, Cannabis Sativa. The Rise of a Natural Health Authority Some people experience dry mouth, dizziness, and changes in appetite. CBD has been mentioned in numerous studies for its ability to reduce anxiety and help individuals manage stress. However, it can also reduce pain, increase appetite, assist people with insomnia, and reduce cancer cells throughout the body. Dr. Axe reflects that when he first started his career, “a lot more people questioned” natural medicine. What happened to Dr. Josh Axe with his back injury has profoundly influenced his health philosophy, leading to a more integrated approach that places greater emphasis on the mind-body connection. Their lifestyle reflects the principles they advocate—focused on natural health, fitness, and family. It’s one of the plant’s many compounds and is a high-concentration cannabinoid. We are a team of experts committed to promoting health & wellness through education, support, and awareness. After giving birth to her newborn daughter, Livvy stepped down from her full-time position at the Children’s Hospital of New Jersey. Hemp-derived products are legal in all 50 states as long as they contain less than 0.3% of THC — which isn’t enough to get anyone high but still evokes the entourage effect. It wasn’t until scientists started studying effects of cannabis that they discovered this biochemical communication system in the human body. Some researchers are finding that cannabinoids act as ligands that bind to proteins and modulate receptors in the brain and throughout the body. Our hemp articles discuss nutrition facts, health benefits, uses, precautions and more. More importantly, CBD is preferred by people looking for intoxication-free relief. This means both THC and CBD sourced from marijuana are illegal, except for the growing number of states that allow for recreational marijuana use, such as Colorado and California. On the other hand, marijuana is a Schedule I controlled substance. Although most align with federal policy, some are more restrictive and it’s best to research the laws of the particular state you’re interested in. Although cannabinoids all have similar structures, they display a wide array of actions at each of the different receptor sites. CB2 receptors are found mostly in the immune system. All cannabinoids function as ligands, meaning they dock onto the binding site of a protein and have the ability to modulate a receptor’s behavior. Dr. Axe has been a regular guest expert on The Dr. Oz Show, covering topics such as the gut microbiome, weight loss, digestive health (including leaky gut and candida), and herbal medicine. The institute teaches ancient principles of health to the modern world and provides educational platforms reaching millions worldwide. Dr. Axe founded The Health Institute, which offers programs and certifications for health practitioners, health coaches, and wellness advocates. Dr. Josh Axe and Jordan Rubin are the founders of Ancient Nutrition, where the mission is to restore health, strength and vitality by providing history’s healthiest whole food nutrients to the modern world. National Library of Medicine, cannabis use dates back at least 3,000 years. CBD does not produce a euphoric “high” or psychoactive effect because it doesn’t affect the same receptors as THC. Cannabis oil and CBD oil are not the same thing. Cannabinoids are a group of 21-carbon–containing terpenophenolic compounds produced uniquely by cannabis species. These trichomes contain high amounts of tetrahydrocannabinol (called THC), which is the cannabinoid most known for its psychoactive properties. ΒCP is a major component in cannabis and a common constituent found in essential oils of numerous spice and plant foods. It was once believed that only THC and a few other phytocannabinoids affected these receptors, but we are now learning that other plants and foods can affect them as well. And although thousands of studies have been conducted on the role of cannabinoids in the body, scientists believe that we are just beginning to scratch the surface. This incredible system is made up of endocannabinoid receptors that respond to cannabinoid compounds, which can be found in cannabis and a number of other plants. While both THC and CBD can be found in marijuana, CBD is also plentiful in hemp. It’s found in varying amounts in many recreational strains, and breeders have been working hard to create high-CBD strains of marijuana for medical users. What’s the difference between THC and CBD when it comes to marijuana and hemp? If the THC levels in CBD oil are high enough, it could show up via drug testing. One of the biggest worries people have when looking into THC vs CBD is whether the compounds will cause them to fail a drug test. A strong flavor profile tends to enhance the overall experience, making it easier for individuals to include these gummies in their daily health routine without the reluctance that often comes with other forms of supplementation.Capturing the entire phytochemical profile of the plant allows the manufacturer to maximize the therapeutic value of the end product.In today’s world of power tools and heavy machinery, the humble axe might seem like a relic of the past….Most strains of marijuana have significant levels of THC, but dispensaries also sell high-CBD strains (particularly for medical patients).In glial cells, on astrocytes the presence of CB1R has been reported on both the cell membrane (Ref. 41F) and the mitochondrial membrane .THC produces the mind-altering, euphoric effects of the plant.Dr. Axe’s journey offers a powerful model of resilience in the face of health challenges. For instance, preclinical evidence demonstrated that CBD-induced anxiolytic effects depend on its 5-HT1A activity 81,82. Thus, the specific biological/pharmacological effects of THC and CBD are most likely due to their pharmacological promiscuity rather than merely to CBR activity. On the other hand, CBD acts as an agonist of the receptors/channels TRPA1, TRPV1-3, PPARγ, 5-HT1A, and A2 and A1 adenosine and as an antagonist of the receptors GPR55, GPR18, and 5-HT3A. Although both THC and CBD mainly interact with metabotropic CB1 and CB2, THC binds both with nanomolar affinity, while CBD displays micromolar affinity 65,66,67,68; additionally, they exert completely different actions on these two receptors (see Figure 4). However, its psychoactive effects are distinct from THC. As the main psychoactive component of cannabis, THC is largely responsible for the cannabis high. By definition, marijuana contains over 0.3% THC, with some strains reaching concentrations as high as 30%. CBD has rapidly grown in popularity in the past several years as a natural option for relieving a wide variety of symptoms and conditions. In regular cannabis, CBD is the second most prevalent cannabinoid. When you push a component like THC too high, or isolate a component like CBD at the other components’ expense, you can reduce their beneficial effects. Synergy is when two or more substances or other agents interact and cooperate to produce a combined effect that’s greater than the sum of their separate effects. However, combine the both of them and you instantly have a whole range of new therapies and effects available to you. According to the research, even chronic human users of CBD showed no type of negative psychiatric, neurological or clinical effects. Capturing the entire phytochemical profile of the plant allows the manufacturer to maximize the therapeutic value of the end product. That’s why full-spectrum CBD oils are the preferred format instead of broad-spectrum CBD and isolates. Similar to how CBD can dampen the intoxication from THC, some of the effects of CBD are more pronounced when you add a little bit of THC to the mix. Broad-spectrum CBD oils and isolates are a good alternative if you want a THC-free product. Unfortunately, the problem with many CBD oils found online is that they are contaminated with significant THC levels due to the lack of regulation and third-party testing. In addition to this, minor cannabinoids and terpenes within individual marijuana strains may also affect the way they work. Armed with this knowledge, medical marijuana users can customize their medicine, while recreational users can better control what kind of high they experience. This is because they all work on different receptors in the brain and body, with some paving the way for others to work more effectively. In addition to CBD smoothing out the unwanted effects of THC, research suggests that the whole spectrum of cannabinoids may function to help individual ones work even better. One of the reasons for this is that the effects of concentrated THC (natural or synthetic) can be powerful and dizzying. Although CBD isolate is a more concentrated form of cannabidiol, this doesn’t mean that it has greater effects. There are also a number of ways that CBD can be extracted to make both CBD isolates and full spectrum products, with CO2 extraction being one of the best options. When it comes to CBD isolate and full spectrum oil similarities, there’s one simple example — both contain cannabidiol. But do keep in mind that hemp farmers and manufacturers need to follow specific guidelines, so always look for CBD from a reputable company with a certificate of analysis (COA). The “cannabis spectrum” refers to this balance of cannabinoid concentrations, which influence the cannabis product’s profile. Interestingly, it has been demonstrated that the intoxication effects (i.e., dissociative states) induced by CBD may depend on individual cannabinoid history 194,195. Interestingly, this study pointed out the positive correlation between AEA levels and clinical improvements, suggesting that the inhibition of AEA degradation induced by CBD may be implicated in its antipsychotic effects, representing a new approach in treating schizophrenia. For instance, pretreatment with CBD did not improve the outcomes of therapy sessions in a relatively large group of patients diagnosed with anxiety (i.e., social anxiety disorder or panic disorder with agoraphobia) . By binding to the same receptors, THC is psychoactive, while CBD has anxiolytic and antipsychotic properties. In general, this is a website that promotes dangerous homeopathic remedies for serious conditions that require real medical attention. The website is owned by Joshua Lee Axe and is funded through advertising and a shop that sells or markets products. He has a doctorate in chiropractic and naturopathic medicine; he is not a medical doctor. Scientists believe that these specific compounds that are able to interact with proteins of the endocannabinoid system, offering beneficial effects. Kava contains compounds that are called kavalactones, and one in particular, yangonin, is able to interact directly with CB1 receptors. The plant has been used for thousands of years and today, it is often used as well. Echinacea features fatty acid compounds called N-acylethanolamines, which are known to bind to and activate cannabinoid receptors. Black pepper, lavender, clove, rosemary and cinnamon essential oils contain a sesquiterpenoid that’s called beta-caryophyllene (βCP). Copaiba oil resin, or Copaifera reticulata, has been used traditionally to support health. When scientists analyzed animal tissue, they discovered an enzymatic pathway that converts omega-3-derived endocannabinoids into molecules that bind to receptors in the immune system.Ad Cacao also works to naturally function to deactivate fatty acid amide hydrolase (FAAH), which is an enzyme that’s part of the endocannabinoid system and breaks down anandamide. Some studies indicate that anandamide is well-equipped with endocannabinoid-binding receptors and releases chemicals that have a similar biological mechanism as THC. When engaging with CB2 receptors, these compounds in echinacea can directly affect the body. Nevertheless, starting from the early 2000s, many countries have legalized cannabis for medical purposes and some of them even for recreational use.While THC isn’t the only cannabinoid capable of inducing intoxication, it’s the only one that occurs in concentrations significant enough to produce a high.THC and CBD are the two most abundant cannabinoids found in marijuana.Moreover, repeated CBD-THC exposure during adolescence induced pronounced, long-lasting effects in female but not male rats .It is also recommended to consult with a healthcare professional before starting CBD use.The show features interviews with health experts, entrepreneurs, and thought leaders. The term cannabis (popularly known as marijuana) is used to describe a product of the Cannabis sativa plant that is bred for its potent, sticky glands that are known as trichomes. Both THC and CBD provide people with positive effects on their own, but when you combine them together, even more benefits can happen. Certain studies prove high THC marijuana strains could lead to long-term negative psychiatric effects if adolescents consume it. Although it’s well-known that THC causes you to feel “high,” many patients value CBD for its medical and non-psychoactive effects. The pleasant taste of gummies can make the anxiety of taking medications less stressful, often leading to better adherence among individuals needing continuous dosing of CBD for pain relief. Commonly found additives may include natural flavors, sweeteners, and potential nutritional supplements like vitamins or herbal extracts. The extraction process also plays a crucial role, with methods like CO2 extraction being favored for preserving the purity and potency of cannabinoids. Peak 8 CBD Gummies advertise that they use premium CBD extracted from organically grown hemp. CBD doesn’t bind as well with these two receptors, which is one of the reasons it fails to produce a high. Although the compounds evolve from the same cannabinoid and they can be ingested in similar ways, they are different in everything from their method of action to many of their effects. Both THC and CBD can be ingested through smoking, vaping, edibles, oils, and tinctures. The exact effect depends on what natural cannabinoid level you have in your system, how much THC you consume and various other health factors. When abundantly produced, natural cannabinoids induce a mildly euphoric sensation similar to the effect of intense exercise. Cannabinoids are part of your endocannabinoid system (ECS), and they actively bind to certain cell receptors in your body. CBD, which refers to cannabidiol, is a chemical compound that comes from the cannabis sativa plant. Studies suggest that THC can produce the same neuroprotective effects. Moreover, some researchers claim that CBD can also support healthy sleep cycles. The difference between CBD vs. THC is that the former offers a relaxing sensation to your body without producing a mellow physical high. Instead, CBD exerts its actions by working on multiple receptor-based and receptor-independent pathways throughout the body. For example, THC is the stimulant of CB1 and CB2 receptors, while CBD has little effect on both. The FDA has approved Epidiolex, a CBD-based drug for the treatment of certain types of epilepsy, which further proves CBD’s medicinal value. It interacts with the ECS but does not bind directly to the CB1 receptors in the brain. It is non-intoxicating, making it a good option for those who want therapeutic benefits without the risk of cognitive impairment. A recent study found that cannabinoids are produced naturally in the body from omega-3 fatty acids. You’ve probably heard about the many omega-3 benefits before, but researchers are discovering that some of these benefits come from the body’s ability to convert omega-3 foods into endocannabinoids. More research is needed to determine exactly how these non-cannabis CBG compounds work within the body, but researchers believe that it begins from the plant’s aromatic acid. These particular compounds are known to be one of the most structurally diversified types of phytocannabinoids that are found in the cannabis plant. © 2026 dranthonygustin.com. Eric Edmeades is a globally recognized authority in health, practical psychology, and behavioral transformation. It’s actually just the opposite and we have a lot in common, starting with a similar background and believing in a lot of the same nutritional and health philosophies. Despite what most people think, we’re not mortal enemies, as I mention in the episode. A strong flavor profile tends to enhance the overall experience, making it easier for individuals to include these gummies in their daily health routine without the reluctance that often comes with other forms of supplementation. Many reviewers appreciate that the gummies offer a tasty way to consume CBD, contrasting with the earthy note of oils or the inconvenience of tinctures. These testimonials reveal the diversity of experiences, indicating that while some find the products life-changing, others may not perceive a significant impact. It is non-intoxicating, making it a good option for those who want therapeutic benefits without the risk of cognitive impairment.In a very recent study, Huffstetler and colleagues (2023) demonstrated that a single CBD administration (10 or 20 mg/kg, i.p.) induced changes in mouse behavior in a dose-, sex-, and anxiety-state-dependent manner.Dr. Axe has been a regular guest expert on The Dr. Oz Show, covering topics such as the gut microbiome, weight loss, digestive health (including leaky gut and candida), and herbal medicine.When engaging with CB2 receptors, these compounds in echinacea can directly affect the body.Dr. Axe founded The Health Institute, which offers programs and certifications for health practitioners, health coaches, and wellness advocates.Armed with this knowledge, medical marijuana users can customize their medicine, while recreational users can better control what kind of high they experience.Since several products containing both of these compounds have been marketed in the last decade, people, including adolescents, are consuming CBD by itself. Of the 100+ cannabinoids that have been identified in the cannabis species, CBD and THC have been studied the most extensively for their effects on the endocannabinoid system. We are just beginning to understand this body system and already it’s believed to be one of the most important physiological systems involved in maintaining our health. When scientists started studying the beneficial effects of cannabis, specifically those of THC, they discovered a biochemical communication system in the body — now called the endocannabinoid system. Long story short, your CBD products are legal as long as they contain 0.3% of THC or less. However, THC can also lead to a huge appetite boost; whether you consider this a negative effect or not depends on your relationship with food and overall physical health (3). That being said, CBD may cause drug interactions by preventing your liver from metabolizing most pharmaceutical medications (2). Cannabidiol versus tetrahydrocannabinol. Have a healthy and blessed week! Is meat a healthy part of our diet? Nicholas Pintori gratefully acknowledges the Fondazione Zardi-Gori for the postdoctoral fellowship within the Zardi-Gori 2020 call in the field of drug addiction and comorbid diseases. It’s also important to note that CBD and THC are best used together, especially in combination with other cannabinoids, terpenes, and flavonoids naturally present in cannabis. Cannabis drug tests look for the metabolites of THC, which means that using marijuana and other THC-rich products will likely result in a positive test. However, CBD is best known for coming in the form of full-spectrum CBD oil and other hemp-derived wellness products. It also effectively mimics the effects of inhibitors like acetylsalicylic acid (Aspirin), ibuprofen, and naproxen. It does not bind with the CB1 and CB2 receptors in the same way as THC, but it appears to interfere with those molecules that do bother the receptors. When it binds to the CB1 receptors, it disrupts the flow and sends unconventional signals to the brain. Anything that disrupts the movement of neural messages across the synapses antagonizes body/brain behavior. Therefore, although preclinical and clinical evidence obtained in adults suggests that CBD is “safe”, it cannot be ruled out that there are possible addictive effects induced by CBD exposure during adolescence. For instance, Klein and colleagues (2011) demonstrate that CBD potentiates the psychoactive and physiological effects of THC in adolescent rats, most likely acting on its metabolism . Although multiple studies support the Gateway Hypothesis—a causal relation between adolescent THC exposure and development of different SUDs later in life—numerous pieces of evidence have failed to provide support for this theory. Moreover, while the rewarding and addictive properties of THC have been widely evaluated in both youths and adults 39,95,96,120, little is known about the rewarding effects of CBD in adolescence, both at clinical and preclinical levels. Relying mostly on anecdotal history, it has made broad medical claims for decades. The hem-derived CBD industry has been a sleepy arm of the natural, organic, and herbal world. The multiple claims of physical and psychological properties and benefits bother the enforcement agency. Enter your email address below to receive exclusive information about AllBud and the Cannabis industry. Everybody is different, so focus on what works best for you. Plus, pure CBD oil will not contain additives that come with side effects. Generally speaking, ingesting CBD oils using a dropper is typically the easiest way to stay in control of exactly how much you are taking. You can use lotions or oils containing CBD on your skin, place a few drops in your mouth or vape CBD oil. When you are shopping for CBD oil, look for products that have been tested for contaminants and for CBD vs. THC levels. They often report a relaxed state of mind, reduced physical tension, bouts of euphoria, giggliness, and even signs of improved cognition. Most cannabis users consider the high from THC as a pleasurable sensation. Nevertheless, CBD has a lot of documented therapeutic benefits as well. While THC isn’t the only cannabinoid capable of inducing intoxication, it’s the only one that occurs in concentrations significant enough to produce a high. You may have noticed that CBD products are everywhere these days. There are several ways to use CBD, including in capsule, topical, edible or drop forms. This can be a great thing for consumers who are looking to get the best CBD products out there. As the popularity of CBD products continues to grow, more manufacturers are jumping on the bandwagon. Hemp seed oil is also popular because it serves as a source of important nutrients, including polyunsaturated fatty acids, terpenes and proteins. Though it's often well-tolerated, CBD can cause side effects, such as dry mouth, diarrhea, reduced appetite, drowsiness and fatigue. Food, drinks and beauty products are among the many CBD-infused products available online. CBD doesn't contain tetrahydrocannabinol (THC), the psychoactive ingredient found in marijuana that produces a high. Nevertheless, starting from the early 2000s, many countries have legalized cannabis for medical purposes and some of them even for recreational use. These two compounds are remarkably similar in their chemical structures (see Figure 1); indeed, they bind to the same cannabinoid receptors (CB1 and CB2) while leading to completely different effects (for details, see Section 1.3). It was only in the 20th century that cannabis recreational use arose, and many countries scheduled it as an illicit drug 1,2. For years, many patients have insisted that they got greater relief from simply smoking marijuana than from taking THC as a natural concentrate or pharmaceutical synthetic form. This can create some rather powerful effects, whether the product is a THC tincture or an oil with a high percentage of CBD. A synthetic form of tetrahydrocannabinol, dronabinol has been approved to treat people with nausea, vomiting, and low appetite due to chemotherapy or AIDS. Because so many studies have shown positive results, the pharmaceutical industry has worked to find ways to turn marijuana into prescription medicine. Meanwhile, CBD’s antipsychotic effects make it a potentially effective treatment for people with schizophrenia. ExampleLife is a website that provides you with the latest and most comprehensive information about life, including health, food, travel, and more. CBD interacts with the body's endocannabinoid system, which is involved in regulating various functions such as mood, sleep, and immunity. Research has shown that CBD may have a range of therapeutic benefits, including reducing inflammation, relieving pain, and promoting relaxation. These very small amounts of THC will not leave you feeling “high” or intoxicated, but will work with CBD and other cannabinoid compounds in the product to have greater beneficial effects. This, combined with the misrepresentation of CBD as a non-psychoactive cannabinoid, tends to make people believe that THC is questionable. The body uses the protein collagen to maintain healthy tissues, from your gut lining to your skin. Collagen is an important protein for all of us—and there are a number of ways plant-based eaters can promote healthy collagen production.Read More How To Boost Your Body’s Collagen Production On A Plant-Based Diet Reap the amazing health benefits of bone broth more often with these tips and recipes for cooking and baking with it.Read More 8 Ways To Enjoy Bone Broth—Because It’s SO Good For You Dr. Axe founded the website DrAxe.com, which is one the top natural health websites in the world today. This clinic, called Exodus Health Center, operated from 2008 to 2013 and established his reputation as an innovative healthcare practitioner. Dr. Josh Axe, DC, DNM, CNS, is a doctor of chiropractic, certified doctor of natural medicine, and clinical nutritionist who has become one of the most influential figures in the natural health movement. His interest in medical cannabis started decades ago with the historical study of ancient medicine. CBD is nonpsychoactive and used for anti-inflammatory, analgesic, and anti-anxiety effects. In some individuals, especially those with a history of mental health disorders, THC can cause anxiety or paranoia. Clinical controlled-setting studies (dose, composition, and timing) with larger sample sizes and longer follow-up periods are necessary to deeply understand the toxic and therapeutic properties of CBD in youth. One of the major concerns is the inconsistency in CBD and THC contents among commercial products, due to the lack of rigorous lab monitoring and legal regulation. Although CBD treatment did not induce serious adverse effects, 80.6% of patients reported fatigue, low mood, cold chills, and hot flushes . Masataka (2019) reported that repeated CBD treatment (300 mg/kg, 4 weeks) significantly decreased anxiety in teenagers with social anxiety disorders. Hemp is typically grown for industrial purposes, as it’s used to make clothing, paper, ropes, carpets, construction materials and plastic composites. In fact, CBD is being used in conjunction with THC for more favorable effects. For this reason, interest in non-intoxicating phytocannabinoids, such as CBD, has substantially increased in recent years. That’s why most cannabis grown for recreational purposes are typically very low in CBD and high in THC. Terpenes, the aroma molecules found in essential oils, engage CB2, the cannabinoid receptor that’s found predominantly in the immune system. Endocannabinoid receptors are found throughout our bodies — in our brains, immune cells, connective tissues, glands and organs. This was opposed by physicians who were not required to pay a special tax for prescribing cannabis, use special order forms to obtain it and keep records detailing its professional use.