By now, things like regular exercise and healthy eating habits should be part of your everyday routine. They help you stay on track and maintain weight loss over time. These points are key to the Mounjaro weight loss journey. In that case, you'll move to a 7.5mg once weekly injection and as weeks go by, your dosage may increase until maintenance. You may start to notice positive changes in your well-being as well — perhaps you have more energy, can sleep better, or feel like making healthier choices is becoming second nature. This is normal and the result of your body adjusting to the medication. You’ll start off on the lowest dose (2.5mg). Here’s what a typical treatment regimen with Mounjaro looks like. I always just felt hungry throughout the dieting process and it actually kinda gets you down” “I was always on this yo-yo diet scenario, which never worked. Chronic stress can cause you to emotionally eat and lead to cortisol-induced — weight gain that typically shows up around the midsection and is often referred to as a 'hormonal belly'. In this guide, we’ll break down the typical Mounjaro weight loss timeline—week by week and month by month. At six months, average weight loss was 10% on tirzepatide and about 6% on semaglutide. In just four months of taking weight loss medication, she lost 22kg (48.5 lbs). Gradual weight loss is also the healthiest way to lose weight as it helps forge habits that sustain long-lasting results. How To Lose Weight During Menopause: Medical And Lifestyle Strategies Want to make the most of your first 3 months on Mounjaro? Want to make the most of your first 2 months on Mounjaro? Everyone follows their own journey, but many people recognise the broad pattern below. Use our Weight Loss Calculator below to find out how much weight you could lose on Mounjaro. Adding resistance training to your routine can also help build muscle mass, which boosts metabolism and supports weight management. Try to get at least 150 minutes of moderate-intensity exercise each week. By prioritising your sleep and aiming for 7-9 hours per night, your overall health will improve. You can lose up to 26% of your body weight while building habits that actually last. Evidence suggests that people who stop tirzepatide treatment tend to regain some or all of the weight they lost, especially if lifestyle changes are not maintained. Appetite changes often begin within the first few weeks, and early weight loss is commonly seen between weeks 4 and 8. Studies of tirzepatide and other weight loss medicines show a tendency for weight to return when treatment is withdrawn, highlighting the need for long term strategies. The month-by-month patterns shown here draw on findings from published clinical trials, real-world anonymised patient feedback, and wider research on how GLP-1 treatments influence weight over time. In the real-world comparative effectiveness study, tirzepatide proved more effective for weight loss within a year of treatment.These include your diet, exercise levels, age, metabolism and more.Some people may lose more and some may lose less.Though similar in their mechanisms of action, they are different medications.”It will still have an effect, though it won’t be as strong as at higher doses.For those lucky enough to experience these early wins, the first month set the tone for what felt like real, lasting change.Now that you have an idea of what Mounjaro weight loss could look like on a week-by-week basis, you may feel ready to take the first step on the journey.But it’s also totally fine if you’re happy at 5mg.With his Urology background, he has been able to leverage his experience in men’s health with the clinical product team. One of the biggest things I learned when weaning off Mounjaro was that it’s important to stick to the habits and portion sizes you developed while on the medication. I didn't want to continue losing weight and get into a weight range that wasn't sustainable or healthy for me. Many people who are on tirzepatide and semaglutide injections experience significant muscle loss while taking the medication, and I was determined not to let that be the case for me. You may be entitled to compensation if you were injured after taking a medication like Ozempic, Saxenda or Wegovy. Mounjaro and Ozempic are weekly injections approved by the FDA for Type 2 diabetes. With his Urology background, he has been able to leverage his experience in men’s health with the clinical product team. It’s not a lot, but it’s a good start for lasting weight loss. In the first month, you might lose 1-2 pounds each week. A good mounjaro weight loss plan starts with small steps. Yet, with the right mounjaro weight loss tips, you can start strong. We analyzed data from patients after their first 2 months (8 weekly doses) of Mounjaro. Mounjaro was effective at helping people lose weight in a study involving more than 2,500 adults who had obesity (BMI over 30kg/m2) or who were overweight (BMI between 27 and 30 kg/m2) and had at least one weight-related health problem. Mounjaro is also used together with diet and physical activity to help people to lose weight and keep their weight under control. Related article Popular weight-loss and diabetes medications linked to lower risk of some cancers, study finds Discover if Hormone Replacement Therapy (HRT) could help support your weight loss, supported by science. I can go to the fun fair with my kids and get on a ride with them without thinking that I'm too heavy for the ride… that's why I wanted to lose weight. I’ve tried every diet, I've tried weight slimming classes and I was just not happy with my weight. Chantell lost 11kg (25Ibs) and gained endless confidence in just four months on Mounjaro. Since you're less hungry, you'll likely eat fewer calories and enter a caloric deficit, setting the stage for future weight loss. Designed by UK clinicians, this programme gives you the tools you need to make informed decisions, so you can not only lose weight but keep it off well into the future. That's a mouth full, we know, but the way it works is it mimics the hormones that regulate your blood sugar levels and appetite, in turn supporting weight loss by reducing your caloric intake. Read as we do a deep dive into what you can expect during your first few months on Mounjaro and what you can do to maximise your results. Weight loss on Mounjaro is variable, but clinical trials indicate an average of 1 to 2 kg per week, particularly after the initial weeks. If you do switch, you will need to take your first Mounjaro® injection at least one week after your last Wegovy® injection. There is no benefit of taking both at the same time. You must not take Wegovy® and Mounjaro® at the same time. Please be aware if suitable you will be initiated on the most appropriate dose of Wegovy®. At this stage, however, the tirzepatide in your body is starting to reach a steady state. The first few weeks are also important for establishing the habit and routine around taking your medication. You should consult a healthcare professional before taking any medications at the same time as Mounjaro. Does weight loss on Mounjaro slow down after the first month? For those navigating a confusing or inconsistent first month, certain habits made a clear difference. Most people begin at 2.5mg—a dose many now describe as a "primer" more than a fat-burner. "I’ve only lost 9 pounds in 4 months, but I’ve dropped from a size 12 to a 6. That’s massive for me." -u/ChaosTheoryGirl But when medicines like Mounjaro are used as well, people have reported losing up to 25% of their initial weight. After your first 8 weeks, you may wish to increase again to 7.5mg. For weeks 7 and 8, you should continue at a 5mg dosage, providing that you are coping fine at this higher strength. Also I’m not really finishing as much on my plate anymore and I just feel so much healthier and more energetic and I just feel really positive about the future.” It just comes so naturally to me now to go for the healthier option over the unhealthy option. It’s really suppressed my appetite and in doing so has made me make some really healthy choices. Staying consistent with your medication, balanced meals, and movement helps keep your results building over the long term.This dual action is what sets it apart from earlier medications like Wegovy (semaglutide).During weeks 5-8 of your treatment, your Mounjaro dosage typically increases to 5 mg per week.Because all bodies are different, the maximum tolerated dose can differ from person to person.They can help assess whether your current Mounjaro dose is still effective, monitor side effects, and make safe adjustments if your progress slows.Chronic stress can cause you to emotionally eat and lead to cortisol-induced — weight gain that typically shows up around the midsection and is often referred to as a 'hormonal belly'.At the 3-month milestone, you’re building a foundation for long-term health. How effective is Mounjaro for weight loss compared to other medications? Eat small, plain meals, use over-the-counter treatments and take time to rest to allow your body to adjust. Staying committed during weeks 5 to 8 is vital as this is an important phase of your treatment. By this stage, you will typically have lost between 5% and 6% of your starting body weight. Stress is a hindrance to weight loss and can lead to an overproduction of cortisol, which in turn increases your appetite. A 5% weight reduction is believed to have a clinically meaningful effect on metabolic health. The maintenance dose is the strength you will remain on for the duration of your treatment. That means you should reach the maximum Mounjaro maintenance dose of 15 mg per week by week 21. When you start using Mounjaro you will be given a 2.5mg dosage, regardless of your condition or experience with weight loss medications. Around 21% of starting body weight after 1 year of use. Between 5% and 6% of your starting body weight. Up to 4% of starting weight by the end of week 4. In this article, we’ll walk you through what to expect when using Mounjaro for weight loss, week by week. By week 3, most users feel reduced cravings and smaller portions feel satisfying. The 2.5 mg dose is a starter level to help your body adjust. How much can I expect to lose in the first month? Your clinician will review your dosage regularly, especially if your weight loss slows or side effects change. That said, this is also the stage when weight loss can start to really take effect. Beyond just a weight goal, you might also want to think about other aspects of your general health you want to improve. That means that, rather than spiking and falling, levels remain consistent—meaning that the feeling of fullness should endure throughout the week. You may start feeling different, but bear in mind that this may be too small to really notice any physical differences in your body. You’ve got the first two weeks under your belt, and you’re still taking a 2.5mg dosage. By the end of week 4 participants in clinical studies typically lost up to 4% of their starting weight. The dosage remains at 2.5mg but your body has likely adapted to the treatment and you should feel its effects more. This is to give your body more time to adjust to the medication. In the first week, weight loss will vary from person to person. We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life.Chantell lost 11kg (25Ibs) and gained endless confidence in just four months on Mounjaro.Stay consistent, listen to your body, and lean on your support system.You may be entitled to compensation if you were injured after taking a medication like Ozempic, Saxenda or Wegovy.Some have lost up to 22% of their body weight in 72 weeks.This will also boost your health and happiness.The mounjaro weight loss results are not just impressive but also last long.“The doses of semaglutide evaluated in this analysis have not been investigated for chronic weight management, and there are no head-to-head trials that have reported which evaluate Wegovy and tirzepatide,” a spokesperson said in a statement.You’ll still be on the same starting dose during Mounjaro week 3 and 4. By week 3, you might notice changes in your appetite and eating habits. Remember, everyone loses weight differently. But don’t worry, you won’t lose a lot of weight right away. In terms of when weight loss effects “peak” or are most noticeable, these tend to accumulate gradually over months. But looking at clinical trials, people taking Mounjaro lost around 8% to 9 % of their body weight at the 12 week mark. It’s hard to say how much weight you can lose on Mounjaro in 3 months because everyone’s so different. Clinical research tells us that by week 12, most people on Mounjaro will have lost about 8% of their starting weight. The habits you formed back in week one might be starting to feel normal. With the right attitude and support, you can see big weight loss results with Mounjaro.I felt great—I woke up motivated each day because I was seeing consistent results for the first time in a long time.Your weight loss journey with Mounjaro follows a distinct timeline, with specific changes and milestones you can expect along the way.For weeks 7 and 8, you should continue at a 5mg dosage, providing that you are coping fine at this higher strength.Since starting her weight loss journey with Levity, Zion has lost 25 lbs in 6 months using Mounjaro.Wegovy and Mounjaro are both once-weekly injections that help reduce appetite and support weight loss by activating GLP-1 receptors.Eat small, plain meals, use over-the-counter treatments and take time to rest to allow your body to adjust. The first month, I was able to use a manufacturer's coupon to get four Mounjaro injection pens (which is typically a full month's worth of medication when used once per week) for $25. After three months, we still didn’t see any significant changes in my weight, so in the fall of 2022, she asked me if I wanted to try Mounjaro. I felt good on this but for twelve months without it I felt unwell and my glucose shot up regardless of keeping to a good diet and taking insulin. To keep the weight off, mix Mounjaro with a healthy lifestyle. In the first four weeks, some lose 5 pounds. By week 6, they might have lost 6-7% of their starting weight. This ensures you’re on the best mounjaro weight loss schedule for your goals. While some people see dramatic changes right away, others finish their first month on Mounjaro with the same weight they started with—or even slightly more. For some users, the first few weeks on Mounjaro feel nothing short of miraculous. Starting Mounjaro (tirzepatide) can feel like pressing a powerful reset button—but for many, the first month isn’t the instant transformation they expected. Mounjaro® and Wegovy® are both weight loss treatments. Even small weekly changes lead to big changes over time. Incorporating some movement into your week can help speed up results and leave you feeling good. These are examples that everyone can achieve weight loss, if you are given the support, and with a little patience and consistency. Quick weight losers also differ from slow, steady losers. But if you don’t notice anything right away, don’t worry—it doesn’t mean the medication isn’t working. It’s possible you’ll have some side effects, but these tend to be mild and usually resolve as you progress on treatment. For instance, choosing a day for your injection that you can stick to (there’s no “best” day of the week—so pick the one that’s easiest to remember). This helps to minimise the risk of side effects early on, making your journey smoother in the long run. These might include feeling sick or throwing up, or other side effects that come with Mounjaro—like constipation or diarrhoea. Because Mounjaro can stay in the body for up to five days, they’ll need to keep an eye on you and manage any symptoms that come up. As with any medicine, it’s possible to take too much Mounjaro. Comparisons with Other Medications To enhance weight loss results while using Mounjaro, it is recommended to follow a balanced diet that incorporates whole foods. Users can expect an average weight loss of around 21% over the treatment period. During the first two weeks of starting Mounjaro, users may experience mild gastrointestinal side effects such as nausea and diarrhea. If you’re struggling with your current Mounjaro dose, it’s important to speak with your healthcare provider before making any changes.It can be tough to lose weight through changes to diet and exercise alone.Many people have lost a lot of weight with Mounjaro.At six months, average weight loss was 10% on tirzepatide and about 6% on semaglutide.If you do switch, you will need to take your first Mounjaro® injection at least one week after your last Wegovy® injection.You must not take Wegovy® and Mounjaro® at the same time.Some people see early drops, then slow down. Without adequate sleep, you’re more likely to crave food and snacks, contributing to weight gain. Adults should aim to engage in at least 150 minutes of moderate-intensity exercise per week. Consuming too many calories and not burning them off contributes to weight gain. Another dose increase can leave you susceptible to side effects. As you lose fat, preserving muscle mass will help you stay toned. After 8 weeks, it may be time for another dosage increase — provided your body continues to tolerate Mounjaro well. By week 6, you may lose up to 6% of your starting weight, and by week 8, around 7% . While significant weight loss typically doesn't happen immediately, some people experience a decrease in appetite and food noise, which is the first sign that Mounjaro is starting to work. Research favors the use up to 72 weeks for weight reduction and metabolic health. Everyone experiences the medication differently, and some people won't experience side effects at all, but you may start experiencing common side effects at this time, to varying degrees of intensity. Engaging in consistent exercise routines can complement the medication regimen, leading to better results in achieving weight loss goals. This approach can optimize the effectiveness of the medication and support overall health during the treatment period. In this guide, discover more about what to expect week by week on Mounjaro and how to stay on track even when progress feels slower. Mounjaro is a popular new weight loss medicine in the UK that helps control appetite, blood sugar, and metabolism. However, Novo Nordisk markets Ozempic for Diabetes management and not for weight loss. To successfully navigate the maintenance phase, dedication to your prescribed treatment plan is crucial. The 7.5 mg maintenance dose helps sustain the appetite-suppressing benefits while minimizing potential side effects. Your healthcare provider will monitor your progress during this phase to ensure the dosage remains appropriate for your needs. Understanding these factors can help in planning a sustainable weight management strategy. The combination of appetite suppression and hormonal regulation creates an optimal environment for steady weight reduction. Be sure to include some strength training too - muscle training helps maintain muscle mass and metabolism, supporting long-term weight management. Include high-fibre foods to help keep you full and support digestive health. Make sure you are eating a balanced diet rich in whole foods like fruits, vegetables, lean proteins, and whole grains. Mounjaro is approved for use when used alongside a reduced calorie diet and increased physical activity. Mounjaro should never be used in people who have a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2). Others mentioned increased energy, better sleep, more balanced moods, or lower blood sugar—even in the absence of major weight changes. "For the first time, food wasn’t the centre of my thoughts. That silence in my head? That was worth everything." -u/Conscious-Cat3662 For some, simply feeling in control of their appetite again was a huge shift—after years or decades of battling cravings. Not all victories in the first month on Mounjaro show up on the scale. These mixed experiences highlight that progress isn’t always linear—and even a "quiet" week on the scale may be part of a bigger metabolic shift. The combination of physical changes and psychological improvements creates a positive feedback loop, reinforcing healthy habits and supporting continued weight loss progress. These initial weeks lay the foundation for your weight loss journey. Your body’s response to this medication follows a predictable timeline, helping you set realistic expectations for your weight loss progress. The following sections break down what you can expect week by week during your Mounjaro treatment, helping you navigate your weight loss journey with confidence and clarity. Eating a healthy, calorie-controlled diet is crucial for maximizing weight loss on Mounjaro. It's important to allow your body time to get used to the medication, and the best results are seen once you reach higher doses in future months. By weeks 3-4 of your Mounjaro treatment, you’ll notice significant changes in your weight loss journey. Mounjaro has been shown to help people lose up to 20.9% of their body weight in 72 weeks. Since starting her weight loss journey with Levity, Zion has lost 25 lbs in 6 months using Mounjaro. While you won't yet be to 90 days, hopefully by the end of your second month you're well on your way to positive changes that you'd like to maintain. Physically, you may notice that parts of your body are looking more notably slimmer, with muscles becoming more defined. Of course, increasing your dosage may start to bring back some of these side effects as your body gets used to the increase. Having completed your first month on Mounjaro, you may be ready to increase your dosage up to 5.0 mg, providing that you are coping well on the lower dosage and not experiencing intolerable side effects. This might be your sleep hygiene, your mental health, your fitness, or playing sports that you used to play. First month dosing and medication effects Plus, body dysmorphia is real, and I am no exception to its mental detriment—so it was very important that I chose a weight that I knew was healthy and sustainable for my overall success. I was already doing the “right” things from a traditional weight loss standpoint, but my body just wasn’t responding prior to starting Mounjaro. This dosage slowly increased throughout my six-month journey on the medication until I reached my maximum dosage of 7.5 milligrams once per week. Weight loss, whether you are using medication or not, is a long journey. Having launched in the UK in February 2024, it may be even more effective than other weight loss drugs like Wegovy and Ozempic. In the initial weeks (1-2), users may experience changes in appetite along with some mild side effects. Regular physical activity is crucial for enhancing weight loss outcomes when using Mounjaro. These side effects are typically manageable and may subside as the body adjusts to the medication. The only thing that put me off was seeing other people's side effects.A study from 2022, for instance, found an average of 19.5% body weight loss in patients on tirzepatide after 52 weeks, compared to patients on semaglutide, who lost an average of 13.8% body weight over the same amount of weeks .The next phase of your journey is about making gradual, sustained progress.Safe, realistic weight loss is around 0.5–1 kg per week, if you deem the weight loss to be rapid or too slow, consult with your clinician.People taking tirzepatide injections lost more weight and were more likely to reach specific weight loss targets than those taking semaglutide, according to a new study.For those interested in exploring more about effective weight loss strategies, you might find the Ozempic diet plan helpful.Weight-loss medications work best when combined with healthy lifestyle habits.Seeing no progress on the scale or a slowdown in weight loss are signs of a plateau. Reduced appetite, fewer cravings, slower digestion, and improved insulin response—factors that together support steady, clinically significant weight loss. The findings from this study align with clinical trial results, but the study authors note that more research is needed to compare the effects that tirzepatide and semaglutide have on other key health outcomes, such as heart-related events. Discontinuation was common — more than half of patients stopped their treatment before the end of the study — but rates were similar among those taking tirzepatide and those taking semaglutide. Eli Lilly manufactures tirzepatide under the brand name Mounjaro for diabetes and Zepbound for chronic weight management, while Novo Nordisk manufacturers semaglutide as Ozempic for diabetes and Wegovy for weight management. But 82% of people taking tirzepatide reached this important clinical benchmark, compared with about 67% of those taking semaglutide. Side effects typically improve significantly after the first month as your body adjusts to the medication. Stopping Mounjaro after just one month will likely result in regaining most lost weight, as sustainable habit changes haven’t had time to develop2. In the first month, Mounjaro users average 2-4% weight loss compared to 1.5-3% with Wegovy. Research demonstrates a dose-dependent relationship with Mounjaro, with higher doses generally producing greater weight loss1,3. Because Mounjaro can stay in the body for up to five days, they’ll need to keep an eye on you and manage any symptoms that come up.And once I hit my goal weight, I decided to stop taking it.However, managing these side effects is crucial to ensure that you can stay on track with your weight loss journey.While it is currently under review for the treatment of obesity, some healthcare providers may prescribe it off-label for this use.At the highest dose (15 mg), nausea was reported in 31% of patients, diarrhoea in 23%, vomiting in 12.1%, constipation in 11.7%, and indigestion in 11.3%.Most users reported a noticeable acceleration in results compared to month one, especially those who transitioned to 5 mg.There’s never been a better time - experts believe that over the next decade, tirzepatide will reshape how obesity is managed across the UK.By Mounjaro week 4, the medication will start to reach a steady state—which means that a consistent amount of it stays in your system.“I was always on this yo-yo diet scenario, which never worked.You’ve made it through your first month! The medicine tends to become more effective for weight loss as doses increase and as consistent habits build around food, activity and sleep. I weighed in and within 23 weeks I am within the healthy BMI bracket! Two months into your Mounjaro journey, you may be seeing real change both on the scales, and also in your habits and mindset. Advanced fat transfer and removal techniques to sculpt and enhance your body’s contours. Expertly performed body surgeries to reshape, contour, and enhance your physique. Rejuvenating facial treatments to refresh and enhance your natural radiance. Advanced, non-invasive treatments to rejuvenate your appearance without surgery. Mounjaro is approved for weight loss when combined with a reduced calorie diet and increased physical activity. Some people may experience rapid weight loss, while others may see slower results. You can support the effectiveness of Mounjaro for weight loss by sticking to a diet and exercise plan. Start your weight loss consultation with us today and begin your journey. Set a target for how much weight you want to lose, with smaller, realistic goals in between, but don’t be too harsh if you don’t meet them the first time. If you’re consistent with your dosage and committed to healthy habits, Mounjaro can be a powerful tool in your long-term weight management journey. If you're seeing less than 5% body weight loss by week 12, it may be time to talk to your doctor. The first four weeks of Mounjaro treatment serve as an adjustment phase, with a starting dose of 2.5mg. Real life weight loss often comes with other important changes too, like feeling more confident, having more energy or moving through the day with less pain.Now that your weight loss journey is well underway, you can take time in these weeks to look further and really set out what you want to achieve by taking Mounjaro.After three months, we still didn’t see any significant changes in my weight, so in the fall of 2022, she asked me if I wanted to try Mounjaro."2.5 is just to get you used to the medication—it’s not really therapeutic." -u/MounjaroMakeoverIn another trial, SURMOUNT-4, most people made it to this dose.My body immediately reacted positively to being on Mounjaro. Mounjaro is changing how we think about losing weight. By following these tips and learning from others, you can increase your chances of losing weight with Mounjaro. Good nutrition is important for weight control. This means adjusting your treatment based on side effects. Common ones include nausea, diarrhea, and feeling less hungry. Research shows that you can lose up to 4% of your starting body weight in the first month of Mounjaro treatment. The active ingredient in Mounjaro, tirzepatide, starts working from the first week of treatment, but how much weight you will lose in a month with Mounjaro is unique to you. The results also show that 89% of people on the 10 mg dose and 91% of those assigned the 15 mg/week dose lost at least 5% of their starting body weight. Expert treatments to minimize ageing signs, rejuvenating your skin for a youthful glow. Personalized strategies to maintain and enhance your overall health and vitality. Holistic approaches to boost energy levels and strengthen your immune system for optimal health. See If You Qualify for a Weight Loss and Diabetes Drug Lawsuit This combo boosts your health and helps you lose more weight. Mounjaro is a big deal in weight loss, helping people manage their weight well. To get good results, keep an eye on your mounjaro weight loss progress and make changes if needed. The aim is for your body to get used to the medicine before it can handle more potent doses. You first take a small amount to give your body time to adjust to the new medicine, before eventually moving on to higher strengths. The same principle applies to dosing for Mounjaro, a weekly injection that works by making you feel fuller for longer, and reducing food noise and cravings. Mounjaro dosage schedule Research from Second Nature’s programme5 shows that patients who implement these strategies alongside medication achieve better weight loss outcomes than those using medication alone. Most significant weight loss occurs at higher maintenance doses (5 mg, 10 mg, or 15 mg). The real impact of Mounjaro becomes more apparent after three months of treatment. The SURMOUNT-1 trial data1 shows that while the average weight loss is 2-4% in the first month, the range varies considerably. You’ve made it through your first month! Though it’s totally fine if you aren’t seeing much improvement yet. You’ll hopefully be settling into a more consistent routine with the medication now. Regular monitoring by your healthcare provider ensures optimal dosing and helps track your progress toward your weight loss goals. The stabilized weight loss during this phase brings noticeable changes in body composition. Week 9 marks a significant milestone in your Mounjaro weight loss journey. This adjustment not only triggers additional weight loss progress—users often report a 6-7% reduction in body weight during this phase—but also brings notable psychological benefits. During weeks 5-8 of your treatment, your Mounjaro dosage typically increases to 5 mg per week. "One bad meal didn’t undo the week. One missed workout didn’t break the plan. I had to learn to zoom out." -u/Amazing-Comment-2662 Some of the most helpful advice was simply to stay flexible and kind to yourself in the first month. They found better long-term success by tolerating the medication slowly and steadily. It may be tempting to skip meals in an effort to speed up the weight loss process, but you should resist the temptation, as your body needs fuel to function properly. During the first couple of weeks, you may start to notice subtle changes in your appetite and eating habits. Plus, medication shouldn't be seen as a quick fix, but rather one piece of the weight loss puzzle. Mounjaro, a medication initially developed for managing type 2 diabetes, has gained significant attention for its efficacy as a weight loss drug. Using Mounjaro is not only about taking an injection each week, it is about a full control over your health and developing habits that stick. At week 12, your dose might be dialled up to 10mg. You’ll stay on it for at least four weeks before potentially progressing to 10mg. For some people, this works just fine as their stable dose. You might be feeling nervous, excited, apprehensive, or a combination of all three. Remember that everyone’s results are different, and your journey might not be the same as someone else’s. This titration happens at 2.5mg increments over a four week period—up to 7.5mg, then 10mg, and so on up to 15mg as the maximum dosage. The most significant differences between Ozempic (semaglutide) and Mounjaro (tirzepatide) are their active ingredients and FDA indications. Drugwatch has provided people injured by harmful drugs and devices with reliable answers and experienced legal help since 2009. More than 30 contributors, including product liability attorneys and board-certified physicians, have reviewed our website to ensure it’s medically sound and legally accurate. Your consent to text messaging is not required for a case review and you may opt out of text messages at any time by texting STOP. Patients should consult their healthcare provider to determine which medication is best suited for their specific needs. For the past seven years Zion has struggled to lose weight, impacting her confidence and her desire to date. Mounjaro is administered as a once-weekly subcutaneous injection (into the fatty tissue just under the skin) and should be used alongside a reduced calorie diet and increased physical activity. While it is currently under review for the treatment of obesity, some healthcare providers may prescribe it off-label for this use. Mounjaro is an FDA-approved medication for the treatment of type 2 diabetes. I am a very muscular person, so my body composition allows me to be around 140 to 145 pounds sustainably and maintain a healthy body fat percentage. I think it is so important to speak to a healthcare professional about what a healthy and maintainable weight is for you personally. My body feels stronger, and I feel more empowered and more in control of my health than ever before. Another thing that has absolutely changed is my perspective on using medications alongside traditional weight loss methods. Our Levity experts, made up of qualified healthcare professionals, explore how Ozempic works for weight loss and how to avoid accidental purchases of ‘fake Ozempic’. Levity can help boost your results alongside a healthy diet and regular exercise. To get the best results, focus on eating a healthy, balanced diet with plenty of high-fiber foods, whole grains, and lean proteins. This is due to a process called titration that helps the medication to work more effectively . You should feel like you are fuller for longer which makes it easier to stick to smaller portion sizes and avoid unnecessary snacking. If these side effects worsen or persist it is important to consult with your healthcare provider. If you are experiencing side effects then these may persist into week 2, particularly nausea and constipation. Weight loss in week 2 will also vary from person to person. An increase in dose at week 5 can mean that your side effects return because your body needs time to adjust. However, it is important that you don’t skip meals and adopt healthy lifestyle practices to prevent future weight gain, even after you stop Mounjaro treatment. After three to four weeks of Mounjaro treatment, many people notice their side effects easing. If you’re thinking about incorporating medication into your own routine, you will probably want to know what Mounjaro weight loss could look like on a week-by-week basis. Most users reported a noticeable acceleration in results compared to month one, especially those who transitioned to 5 mg in month 2 and 7.5mg in month 3. Most users reported a noticeable acceleration in results compared to month one, especially those who transitioned to 5 mg. Small, steady progress adds up, and many users find their results accelerate after the first month. Want to make the most of your first month on Mounjaro? The doses and timing described are typical titration steps and may be adjusted by your prescriber. Mounjaro can deliver meaningful changes in just 30 days, especially when paired with healthy habits. We analyzed data from patients after their first month (4 weekly doses) of Mounjaro. Some people lose weight more slowly than the averages. Mounjaro is indicated as an adjunct to a reduced-calorie diet and increased physical activity for weight management, including weight loss and weight maintenance, in adults with an initial Body Mass Index (BMI) of By week 5, most patients move to a 5mg dose, followed by 7.5mg by week 9—though this depends on individual tolerance and your prescriber’s plan. Even with a structured dosing schedule, weight loss on Mounjaro isn’t the same for everyone. Many users begin to notice the first effects of Mounjaro within the first few weeks, including reduced appetite and better control over food portions. This helps reduce side effects while allowing your body to adjust to the medication. Mounjaro uses a titration-based dosing schedule, meaning your dose is gradually increased over time. Mounjaro, also known as tirzepatide, is a medication primarily used for the treatment of type 2 diabetes. Therefore, understanding how to prevent muscle loss on Ozempic is crucial when integrating exercise into your weight loss journey. Focus on whole, unprocessed ingredients to support your weight loss journey and maintain steady blood sugar levels. It had a rebound effect where I lost some weight and after that I just regained it because I wasn't managing it very well. I did try the Cambridge diet, I tried the keto diet and fasting, but it was just a temporary solution. There’s a lot of things that I couldn't do at the weight that I was. While Mounjaro can significantly aid in weight loss, combining it with healthy lifestyle changes can take your results to the next level. Like any medication, Mounjaro can cause side effects, especially during the initial weeks of treatment. Whether on Mounjaro or not, most people experience a weight loss plateau at some point in their journey, where the weight loss slows down or temporarily halts. In patients who have obesity or are overweight with weight-related complications, treatment with Mounjaro resulted in weight loss which was mainly due to loss of fat mass. In a third study, Mounjaro lowered HbA1c by up to 2.5 percentage points after 40 weeks when added to metformin treatment, compared with a decrease of 1.9 percentage points in patients who received semaglutide (another medicine for type 2 diabetes). In two studies, Mounjaro lowered HbA1c by up to 2.1 and 2.6 percentage points after 40 weeks when added to existing treatment consisting of lifestyle changes only or insulin glargine with or without metformin, respectively. Mounjaro works to promote weight loss by mimicking two natural hormones, GLP-1 and GIP, to regulate your appetite and reduce food cravings. There’s never been a better time - experts believe that over the next decade, tirzepatide will reshape how obesity is managed across the UK. Are you thinking about starting Mounjaro (tirzepatide)? Check out our psychology-based weight loss tips and stay on track for good. But also, when you eat enough fibre, you feel fuller for longer, which helps to curb habits like compulsive snacking. Individual responses vary significantly, with some people experiencing faster initial results while others see a more gradual start. This is the messy, real beginning that so many people don’t talk about. It’s a time of adjustment—physically, emotionally, and mentally. In the end, what helped most wasn’t a trick or shortcut—it was patience, consistency, and learning to work with the medication, not just expect it to do the heavy lifting alone. If all goes to plan, you will continue to increase your dosage under the supervision of your clinician by 2.5 mg every four weeks. As you increase your dose, you may experience some Mounjaro side effects, but these can be managed as you have been and should wear off as your body adjusts to the increase. From week 13, the Mounjaro dose can increase to 10 mg per week. If you don’t feel ready to increase your dose at this point, speak to your clinician. We've had the privilege of working with the NHS for over eight years, helping people across the UK take meaningful steps toward a healthier, happier life. However, individual responses vary significantly; some people are highly responsive even to the starter dose. Clinical data suggest slightly faster initial weight loss with Mounjaro compared to Wegovy (semaglutide)1,3. That’s why our weight loss programme includes access to personalised, expert guidance on how to make changes and stick with them. Weight loss is a gradual process, and with Mounjaro, it can take up to 18 months to see the full impact. And then results generally level out at weeks. For instance, your lifestyle (and how well you keep up with your routine) and starting weight can both influence your results. You’ll only go up to higher doses if your prescriber says it’s okay. This is important for your health and the success of Mounjaro. They can help manage them and adjust your treatment. As you use Mounjaro, watch how your body reacts. But, it’s important to stay patient and keep going. Again and again, users shared the same handful of strategies that helped them feel better, stay motivated, and eventually see results—even if the scale wasn’t moving right away. "I assumed the shot would cancel out whatever I ate. It didn’t. I had to relearn how to fuel my body." -u/bikerchiek Many admitted they thought the medication would do all the work, only to realise food choices still mattered. People with type 2 diabetes or insulin resistance often saw health markers improve before the scale moved. "It’s not about what I see on the scale anymore. It’s about how I feel when I wake up." -u/Redshoe9 Several studies have shown that Mounjaro is more effective than Ozempic for blood sugar control and weight loss. While multiple studies show Mounjaro is more effective than Ozempic for weight loss, the FDA has not approved it for that use. While research shows Mounjaro is more effective for blood sugar control and weight loss, it is more expensive and may have additional side effects. To get past it, try more exercise, eat fewer calories, or tweak your mounjaro dose. Seeing no progress on the scale or a slowdown in weight loss are signs of a plateau. Using Mounjaro with healthy eating and exercise is best. You need to take Mounjaro for up to a year in order to see its full effects—an average of 21% body weight loss. You may also experience secondary benefits of being at a healthier weight, such as better sleep hygiene, improvements to your mood, and feeling healthier overall. These things can act as a great motivation to keep going when weight loss plateaus, as it inevitably does at some point in every weight loss journey. If you haven't already, this is a good time to set goals and expectations—such as the target weight that you are looking to achieve, or some goals around habits you'd like to break or build. If you haven't already, now is an excellent time to incorporate strength training into your routine. Because every gram of glycogen is stored with 3g of water, when the energy is released, so too is the water, which will leave your body as waste in urine, stools, and sweat. Before you inject Mounjaro for the first time, we suggest reading our ‘How to use the Mounjaro injection pen' guide. "While the benefits are significant, it’s essential to carefully consider your individual circumstances, potential side effects, and monitoring requirements. Though similar in their mechanisms of action, they are different medications.” “Ozempic is the brand name for the medication Semaglutide and Mounjaro is the brand name for the medication Tirzepetide. However, it can be stopped if your goal weight has been achieved", added the doctor. Taking Ozempic or Mounjaro may interact with certain medications, leading to an increased risk of hypoglycemia and affecting the effectiveness of oral medications due to changes in stomach emptying. Tirzepatide’s 5 mg, 10 mg, and 15 mg doses showed A1C reductions of 2.01, 2.24 and 2.30, respectively, surpassing semaglutide’s 1.86 reduction at the 1 mg dose. In the SURPASS-2 trial, tirzepatide outperformed semaglutide in reducing A1C levels. The more effective medication depends on your individual needs.