Data analyzed by Epic Research showed an increase in use of these drugs by 40-fold between 2017 and 2021, estimating that six million Americans are now on either Ozempic or Mounjaro. Name brand GLP-1 drugs like Ozempic and Wegovy have quickly become household names, akin to Tylenol or Advil, and their rise in popularity is only increasing. Early data suggest tirzepatide may provide stronger weight loss once it becomes available. With medical guidance, FDA-approved options, and real support, you can lose weight and keep it off without guilt, guessing, or gimmicks. Choosing the best GLP-1 for weight loss isn’t about hype—it’s about results, safety, and finding what fits your body and goals. Thomas Hilbert of PWL agrees – “With the new class of weight loss injections, medical oversight is not only the key to success but also the key to esthetically pleasing results.” Today’s best GLP-1s for weight loss are injectables given weekly, requiring a prescription and medical supervision. 🔹 Book your free consultation today🔹 Learn more about GLP-1 injections for weight loss🔹 Experience the 4Ever Young difference and reclaim your confidence While the benefits are compelling, GLP-1 medications are not without risks. GLP-1 medications improve insulin sensitivity and reduce post-meal glucose spikes. Blood Sugar Control and Diabetes Support GLP-1 medications improve insulin sensitivity and reduce post-meal glucose spikes. This is normal and usually temporary when monitored by a weight loss doctor. These changes often happen within days, even before weight loss begins. A professional consultation ensures the medication and dosage match your personal health needs. Are you struggling with your weight and its impact on your health? "Still, even when you're older, weight loss has many benefits. So, don't wait to reach out for help." So how do you know when your weight is stable? The abdomen is often where people see the most changes. Drugs like Semaglutide (commonly known as Ozempic or Wegovy) are making headlines for their powerful weight-loss benefits. “It’s a protein, a peptide, which means that when you take it orally, the stomach disintegrates some of it. “There are patients who are still very reluctant to do the weekly injection. Tummy Tuck After GLP-1 Weight Loss (Semaglutide): When Weight Stabilization Matters + Best Timing GLP-1 receptor agonists (such as semaglutide, liraglutide, and tirzepatide) are best known for their role in weight loss, but their benefits go far deeper. Fiber is particularly helpful for GLP-1 users because constipation and other digestive issues can be side effects of the medications. Taking GLP-1 medications reduces the appetite and, therefore, total food intake. Schedule your medical weight loss consultation at Healthy Solutions Medspa or give our office a call. Since oral tirzepatide is still in development, exact pricing isn’t available.Misconceptions still abound with GLP-1 medications.While the benefits are undeniable, the blockbuster growth and use of GLP-1 drugs has also highlighted potential side effects.It’s a hormone your body naturally makes to help control blood sugar, insulin, and digestion.Choosing the best GLP-1 for weight loss isn’t about hype—it’s about results, safety, and finding what fits your body and goals.The once-a-day semaglutide pill is approved for reducing the risk of heart disease and Type 2 diabetes, the company said in a statement Monday.All other GLP-1 drugs available in Canada are injectables to date. Both of them work at the level of the pancreas and at the level of the brain and other organs in the body,” adds Jay, who has also done consulting work for Novo Nordisk. She's also co-author of a new book about obesity with Oprah Winfrey, called "Enough." “Not everybody responds to GLP-1,” she tells TODAY.com. NBC News correspondent Liz Kreutz had helpful tips from experts about how to avoid being duped when searching for GLP-1 drugs and other weight-loss products. In its alert, the BBB outlined the most common type of scams consumers will encounter when searching for GLP-1 and other weight-loss drugs. Celebrities like Oprah Winfrey and Serena Williams have also spoken about their use of GLP-1 drugs, which scammers have capitalized on by creating fake endorsements. Weight loss can also cause hair loss, and may be responsible for other rarely reported side effects, such as tiredness. There has also been plenty of media buzz about anecdotal side effects with names like “Ozempic face” and “Ozempic butt.” In clinical trials, about 6 percent of Wegovy and Zepbound users dropped out due to side effects, mostly gastrointestinal issues such as vomiting and nausea. Rybelsus contains oral semaglutide, while tirzepatide targets both GLP-1 and GIP receptors. Side effects are usually manageable, but patients with a history of thyroid cancer or pancreatitis should avoid them. However, many patients choose it for the convenience of a daily pill. People trying to lose weight may opt for long-acting monthly shots instead of weekly injections in the future. “At least 25% of the patients I see don't want anything to do with needles,” she notes. FDA’s decision on whether to approve Orforglipron, Eli Lilly’s daily pill, is expected in April, Reuters reported. The lowest doses cost $149 a month for people paying out of pocket, a cheaper alternative to the injectable Wegovy. The once-daily Wegovy pill is already approved and became available in the U.S. in January 2026. Rybelsus is currently the only FDA-approved oral GLP-1 medication. For years, patients relied on weekly injections like Ozempic (semaglutide) and, more recently, Zepbound (tirzepatide). Most side effects are mild and improve over time. Certain drugs may not mix well with GLP-1s. For example, we note if you have other medical conditions that could affect your ability to lose weight, such as hypothyroidism. In a phase 2 trial funded by the pharmaceutical company, people lost up to 20% of their body weight after taking the medication for almost a year. In a late-stage trial funded by the pharmaceutical company, people lost 20% of their body weight on average after taking the drug for a year and four months. Some people might tolerate amylin analogs better than GLP-1 drugs, or the new option could help people overcome a weight-loss plateau, Jay notes. The next generation of weight-loss drugs will also mimic another natural gut hormone — amylin, which is released by the pancreas in response to food. "Don't go into it expecting the medication to do all the work. Think of it as a tool, not a solution," Pickford says. "I was sleeping for much of the time and didn't notice the nausea," she says. Lynn-Pullman relied on easy-to-digest foods like crackers, applesauce, and dry cereal to combat nausea. Fraudulent websites advertise GLP-1 medications at discounted prices. Scammers are using artificial intelligence to create realistic-looking videos and images of public figures and medical professionals promoting weight-loss products. If you’ve searched for GLP-1 medications online, you’ve probably noticed how crowded and confusing it’s become. Unfortunately, Fiona’s story is one of many as surging interest in GLP-1 medications spurs scammers into action. After placing an order, she received the medication and began taking it, only to experience severe side effects, including migraines, dizziness, and nausea. You may be eating less, but you still need to make sure you’re getting all the nutrients you need.With GLP-1 therapy, you can finally achieve sustainable weight loss supported by science and supervised by professionals who care.Initially approved to manage type 2 diabetes, Rybelsus has since gained attention for its weight loss benefits, especially among people who want to avoid injections.Yes, GLP-1 drugs can inhibit gastric emptying, potentially affecting the absorption of oral contraceptive pills, leading to unplanned pregnancies.A full medical evaluation at a trusted medical spa or by an obesity medicine doctor ensures safe use.At the Center for Wellness (CFW), we help patients understand how these medications affect the whole body, including heart and brain protection, kidney health, and even longevity.GLP-1 weight loss is a medically supervised treatment that uses GLP-1 medications to help regulate appetite, control cravings, and support sustainable weight loss by working with the body’s natural hunger hormones. GLP-1 users are encouraged not to skip fiber just because they are eating less, and to include plant diversity, even in small portions. Reduced food volume and restricted food diversity can lead to less substrate for gut bacteria, slower gastric emptying (which can cause bloating and constipation), while lower fat intake can alter bile acids and the microbiome. For those on the medication, fiber intake can drop without careful planning. Food and Drug Administration last month approved the once-a-day Wegovy pill for weight loss. When patients regain the weight they lost, the cardiovascular benefits of the GLP-1 drug also go away, the report showed. Recent research shows that the effects of GLP-1 medication end shortly after patients stop taking the medication. The once-a-day semaglutide pill is approved for reducing the risk of heart disease and Type 2 diabetes, the company said in a statement Monday. Probiotics and fermented foods She expects retatrutide to become available on the market in 2027, but some online companies have been selling what they claim is the medication, prompting warning letters from the FDA. “For somebody who has a lower BMI of 30, this might be overpowering,” Levy noted. But both experts say not everyone needs to lose that much weight. The most common side effects were nausea, diarrhea, constipation and vomiting. Known as a triple-agonist, this medication from Eli Lilly is not yet approved by the FDA but has produced powerful results in clinical trials. GLP-1s facilitate mindful eating, habit formation, and change maintenance by regulating insulin and hunger. However, not to forget, adopting a healthy lifestyle is beneficial for your overall health in the long run and must be adopted. Your health doesn’t need to be used as a test of your willpower. Let’s be honest, using the finest GLP-1 for losing weight is intelligent, not lazy. Based on patient needs, compounded semaglutide may incorporate Vitamin B6 and B12 to support digestive comfort and energy levels. However, OrderlyMeds differentiates its offering through personalized formulations that include supportive additives tailored to individual health screenings. The telehealth service offers personalized formulations with supportive additives which can be delivered directly to the patient's home address. Ongoing monitoring helps minimize side effects and ensure proper nutrition and metabolic support. GLP-1 medications work on multiple pathways — not just appetite. Once your doctor prescribes the Wegovy pill, you can pick it up at major pharmacies like CVS or through telehealth platforms like Weight Watchers and Ro. “The jury is still out on whether insurance plans will be more likely to cover oral pills,” says Dr. Frank. Unlike fad diets or extreme exercise plans, these medications work with your body’s natural hormones to support appetite control, blood sugar regulation, and long-term health improvements. For those people, GLP-1 (glucagon-like peptide-1) medications designed to control blood sugar levels can also help with weight loss. The benefits are comparable or superior to the benefits of GLP-1 drugs, including dramatic weight loss and secondary long-term health benefits, such as improved blood sugar levels. GLP-1 drugs are powerful medications that may not be appropriate for everybody. Health Canada has approved a GLP-1 pill for the first time. Metsera, a company that was recently bought by Pfizer, is also investigating monthly GLP-1 and amylin analog drugs. The pill versions are especially good for “needle phobic” people, Levy says. It can be swallowed at any time of day without restrictions on food, “so it's easier to take,” Jay notes. Some trial participants slimmed down so dramatically that they stopped taking retatrutide over “perceived excessive weight loss,” Eli Lilly noted in the news release. For some patients, dehydration can lead to acute kidney injury. Pair that with whole-food meals rich in plants, fiber and lean proteins for the best long-term results. To improve your health, a GLP-1 must be part of a more comprehensive approach. "GLP-1s are good for people who either don't qualify for surgery, don't need surgery or who simply don't want it," he said. "When we take away that part of the stomach, patients get a hormone effect that modifies behavior. So, sleeve surgery isn't simply a restriction surgery. It's also a hormonal surgery." What GLP-1 Hormones Do in the Body It is important to note that GLP-1 medications are not fertility aids; rather, they remove obstacles to conception. Schedule an appointment today to explore whether GLP-1 medications are the right fit for your journey toward lasting wellness. This integrated approach helps patients experience not only weight reduction but also better energy, clearer thinking, and long-term resilience. At CFW, we view GLP-1 medications as one tool among many. When the registered dietitian and certified diabetes care and education specialist Jennifer Lynn-Pullman, CDCES, RD, reached 200 lb, she knew that her weight and family history of type 2 diabetes was setting her up for a diabetes diagnosis. Zepbound quieted the food noise and helped Joye reach her goal weight. She had grown up in a home where food was a big part of life, and it made thoughts of eating hard to suppress. Interested individuals can check eligibility and begin the process through the online portal, where licensed providers offer real-time support and community access throughout the treatment process. The latest health and medical news emailed to you every Sunday. However, when given orally, the drug tends to have a “relatively larger dose than we inject so that we get some through the stomach and it doesn’t get destroyed,” she added. And for those patients, the oral alternative could be something to consider. And for most of my patients, I would say with time and experience, they’re able to do the self-injection without too much burden,” he added. These medications include tirzepatide (Mounjaro and Zepbound) and semaglutide (marketed under the names Ozempic and Wegovy). Glucagon-like peptide-1 agonists, or GLP-1s, are prescription drugs that were first authorized to treat type 2 diabetes. We’d love to help you in your weight loss journey while also ensuring you look and feel your best with our aesthetic options to promote health skin and hair. In this guide, we will explore all the common questions one would have regarding GLP-1 drugs. Many clients find that the lowered appetite while taking the medication makes it easier to form healthier habits. However, in certain cases—such as individuals experiencing significant weight loss or those with naturally looser skin due to age—some degree of skin laxity may be unavoidable. More serious side effects are possible, but often occur when patients are taking a dose higher than necessary or from nutritional deficiencies. We help clients navigate options to find the best GLP-1 for weight loss at the best price, whether that is through a typical pharmacy or Lily Direct & Novo Care (the manufacturers’ direct-to-patient pharmacies). They also lessen the brain’s cravings for food and hunger. Smaller servings of food might satisfy you since they slow down digestion. They were soon authorized as weight-loss methods for non-diabetic individuals. Allure Management LLC provides only non-clinical administrative support. Many reputable medical spas offer GLP-1 as part of medical weight loss programs, including at Healthy Solutions Medspa. Some people notice changes within the first two weeks, while visible weight loss typically appears within the first month. These benefits reinforce consistency with medical weight loss programs. We’re committed to providing you with exceptional care and support every step of the way. Your feedback and inquiries are important to us, and we look forward to assisting you on your healthcare journey. Follow us on Facebook, Instagram or Tik Tok to join our community and engage with fellow patients. Stay connected with us on social media for updates, health tips, and more. It’s time to stop guessing—and start succeeding.Wegovy mimics one gut hormone the body produces after eating, GLP-1; and Zepbound mimics two, GLP-1 and GIP.Now, oral semaglutide (Rybelsus) has made daily pill-based GLP-1 therapy possible, opening doors for those who prefer not to use needles.Oprah Winfrey is among the high-profile GLP-1 users, and credits the medication with finally helping her find lasting weight loss.The weight loss reported in the above studies all occurred in volunteers who were also asked to maintain healthy eating and exercise habits.This is why local care from medical professionals at a medical spa often leads to better long-term success than unmonitored online prescriptions.It’s a complex medical condition involving hormones, metabolism, and genetics. For many people, hormones, metabolism, insulin resistance, stress, and inflammation all play a role — which is why traditional diet-and-exercise plans often fall short. Wondering if your insurance will cover the pill version? However, if your insurance covers the Wegovy pill, you could be eligible to pay as little as $25 per month. The 9 mg and 25 mg doses of the Wegovy pill will cost $299. That gives it time to work before you eat anything. Exercise Learn more about obesity, including its causes and the latest treatment options. We’ve also seen data that semaglutide has been shown to have anti-inflammatory and cardiovascular benefits, which can further protect the kidneys from damage.” Studies suggest that GLP-1 receptor agonists may improve cardiovascular outcomes, reduce inflammation and enhance metabolic health. “Taking a few minutes to notice how you are feeling, what is improving and what still feels challenging helps people stay grounded and resilient,” Dr. Wyatt says. Structuring your diet this way can also be helpful in the long run if you eventually plan to stop taking a GLP-1, as protein and fiber are key nutrients for boosting satiety and supporting appetite control. You may be eating less, but you still need to make sure you’re getting all the nutrients you need. But Dr. Wyatt says they are often overlooked entirely when starting a GLP-1 medication, a common mistake. Your mental and emotional wellbeing are just as important as the physical, especially early in a weight-loss journey. For consistent results and safety, the best GLP-1 for weight loss is an FDA-approved version from a reliable source. Additionally, most reputable compounding pharmacies are halting production, meaning any compounded medications still available may come from less reliable or poorly regulated sources. Compounding pharmacies are allowed to produce copies of FDA-approved drugs when a shortage exists, meaning brand-name manufacturers can’t meet demand. GLP-1 drugs now account for more than 7% of all prescriptions in the U.S., according to Truveta Research, a health data company. Oprah Winfrey is among the high-profile GLP-1 users, and credits the medication with finally helping her find lasting weight loss. GLP-1 drugs are not recommended during pregnancy due to unknown effects on fetal development. “You must wait 30 minutes before eating, drinking or taking other oral meds.” Best results will come from keeping it on the night table and taking it the moment you wake up. What forms of GLP-1 would you consider for weight loss? Like the injectable version of the GLP-1 drug, the new pill form still requires a doctor’s prescription. Pharmaceutical company Novo Nordisk’s oral Wegovy pill received Food and Drug Administration approval on December 22, 2025, and officially became available in starter doses of 1.5 mg and 4 mg on January 5, 2026. This new GLP-1 pill may be a cheaper, easier way to lose weight Additional components such as B12 may aid in muscle repair during weight loss and consistent energy as the body adapts to slower digestion and reduced calorie intake.Although these procedures can be expensive, research shows they may lead to several health improvements.This treatment is suitable for both men and women and can be tailored to a wide range of health backgrounds.When prescribed and monitored by a qualified medical provider, GLP-1 medications have been extensively studied.Improvements in metabolic health can often lead to a return to normal reproductive health sooner than expected.After placing an order, she received the medication and began taking it, only to experience severe side effects, including migraines, dizziness, and nausea.The next generation of weight-loss drugs will also mimic another natural gut hormone — amylin, which is released by the pancreas in response to food.Even the most effective weight loss medications won’t work if they don’t fit into your daily life. Weight-Loss Tips From People Who Stopped 'Eating Like Crazy,' Made Simple Changes Nestlé was an early adopter of GLP-1 companion foods when it introduced Vital Pursuit, a new line of high-protein and fiber foods. PepsiCo unveiled a gut-health-friendly soda last year with the launch of Pepsi Prebiotic Cola, which contains 3 grams of prebiotic fiber. The company says the CarobBiom prebiotic fiber is based on the ancient Biblical carob fruit, which naturally contains polyphenols and actively nourishes the gut microbiota.Fiber-forward products take center stage as consumers on GLP-1s prioritize gut health and digestive wellness. Another product explicitly designed for GLP-1 users is Oikos Fusion — touted as the first yogurt in the category with a proprietary combination of whey, leucine, and vitamin D, designed to support their needs in a convenient, easy-to-enjoy format. NPD in fiber-forward foods and drinks marketed for GLP-1 users or aligned with GLP-1 nutritional goals (higher fiber and nutrient density) is gaining traction. Always consult a specialist for specific health diagnosis. Don’t treat it as a substitute for qualified medical opinion. Women planning to conceive should be advised to discontinue GLP-1 therapy to allow the drug to clear from their system before conception. Dr Kumarr notes that one indirect effect of GLP-1 treatment is the induction of ovulation in women with irregular menstrual cycles or infertility issues due to obesity or metabolic imbalance. Improvements in metabolic health can often lead to a return to normal reproductive health sooner than expected. Brand name GLP-1 weight loss medications like Zepbound and Wegovy are more accessible than ever. Outside of narrow exceptions, compounded GLP-1 weight loss medications are no longer permitted by the FDA. If you’re serious about results, stick to FDA-approved GLP-1 medications for weight loss. GLP-1 weight loss medications work by mimicking the glucagon-like peptide-1 hormone, which affects appetite, insulin, and digestion. Let medical support handle the biology of weight loss so you can focus on living your best life. These typically resolve as your body adjusts. With new price drops, many patients are paying 50–70% less than they would have last year. Minor changes in dosage or formulation do not make a compounded drug exempt. Zepbound is licensed for individuals who are obese or overweight and have one or more weight-related medical disorders, just like Wegovy and Saxenda. The FDA-approved form of tirzepatide for weight loss is called Zepbound. In another study, teenagers dropped an average of little more than 2.5 percent of their initial body weight. Adult Saxenda users dropped an average of 8% of their initial body weight in a big clinical trial. Nausea and vomiting were the main side effects that Pickford and Lynn-Pullman experienced in the early days of treatment. "I was barely hitting 800 calories, which isn't enough calories for a child! My protein intake was not sufficient to meet the needs of the weight training I was doing," she says. "I could not finish a meal. I could barely eat half a sandwich. I had no desire to snack between meals. I did not want food in general." To help her lose the weight, Lynn-Pullman started taking Wegovy in May 2023. "I had destroyed my metabolism by starving myself, and my body would hang onto every ounce of fat, literally for dear life," she says. In the majority of people in clinical trials, these side effects have been mild or moderate.That’s why it’s important to weigh the pros and cons of daily pills versus weekly injections.So how do you know when your weight is stable?Most patients take 2–4 weeks off work and avoid strenuous activity for 6 weeks.Rybelsus is currently the only FDA-approved oral GLP-1 medication.Additionally, most reputable compounding pharmacies are halting production, meaning any compounded medications still available may come from less reliable or poorly regulated sources.There has also been plenty of media buzz about anecdotal side effects with names like “Ozempic face” and “Ozempic butt.”The weight loss it produces is “profound” and might be a good fit for people with a very high BMI, Levy added. When prescribed and monitored by a qualified obesity medicine doctor at a trusted medical spa, GLP-1 becomes a powerful tool for sustainable transformation. This approach is far safer than searching endlessly for a weight loss doctor near me online without vetting credentials. A full medical evaluation at a trusted medical spa or by an obesity medicine doctor ensures safe use. GLP-1 medications are not suitable for everyone. Under medical supervision, GLP-1 supports fat loss while preserving lean muscle, especially when paired with protein intake and light resistance training. How to start intuitive eating These cosmetic side effects aren’t unhealthy, and aren’t directly caused by GLP-1s. A small number of users may experience gastrointestinal effects so severe that they need to stop taking the medication. Gastrointestinal issues are usually strongest in first-time users, or when people step up to a larger dosage, but they usually dissipate over time. In the majority of people in clinical trials, these side effects have been mild or moderate. Additionally, a minority of users will find it necessary to discontinue the drug because they cannot tolerate the side effects. Scientists are finding that the drugs may be useful to treat addiction and heart disease. “By lowering blood sugar levels, semaglutide can reduce the strain on the kidneys caused by diabetes. Experts previously told Flow Space that it’s important to practice lifestyle habits like consistent exercise and a nutritionally dense diet to maintain weight loss. While the specific length of treatment depends on your plan with your doctor, it appears that GLP-1s should be used longterm to maintain weight loss. Those who took tirzepatide lost an average of 5.9% of their body weight after three months; 10.1% after six months; and 15.3% after 12 months. "Bariatric surgery is costly, but it's a lot cheaper for patients to have an operation than to be on pricey medications for long periods of time," Dr. Wanko said. Igor Wanko Mboumi, MD, FACS, a bariatric and general surgeon at Franciscan Physician Network Indy Southside Surgical in Indianapolis, explains how bariatric surgery and GLP-1 medications can promote weight loss. Many doctors endorse and prescribe compounded GLP-1 weight loss drugs, but others warn explicitly against their use. If you've lost weight on Semaglutide and think a tummy tuck might be right for you, it's time to find out.People who don’t want to switch from oral HRT should discuss with their doctor the option of using back-up contraception methods.However, Novo Nordisk, Ozempic’s manufacturer, released results from two clinical trials in November 2025 that showed that taking an oral GLP-1 didn’t slow disease progression among people with Alzheimer’s compared to those who took a placebo.Still, results vary depending on the specific drug and whether it’s taken orally or by injection.“Weight loss can open the door to a healthier, more fulfilling life, but it is not the whole story.OrderlyMeds provides compounded GLP-1 injections in all 50 states through an online health screening process, working with licensed providers for a prescription, that ships medications directly to patients' doors.Circadian misalignment alters hormonal signaling and, in turn, can affect food choices and intake.The most commonly reported side effects of semaglutide include gastrointestinal issues, such as nausea, vomiting, diarrhea and constipation. It’s important that you make what you are eating work for your body by choosing nutrient-dense options wherever possible. “Most people notice that hunger quiets down and they are naturally eating less. A top weight loss doctor reveals how to maximize your results and reach your goals You may opt out of these communications at any time by replying STOP to the message or by contacting us directly at GLP-1 medications are not recommended for individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2). GLP-1 medications carry a boxed warning about thyroid C-cell tumors observed in animal studies. Many patients find that these symptoms improve as their body adjusts. However, pills are far more convenient for many people, particularly those who are uncomfortable with weekly injections. It is the approved form of medication for weight loss. A higher-dose medication called Wegovy has been licensed especially for weight loss. However, weight loss is one of the side effects that could help you reach your treatment objectives. Leave the biology of weight loss to medical assistance so you can concentrate on leading the greatest possible life. The most effective GLP-1s for weight loss are weekly injectables that need a prescription and medical monitoring. Unlike weight lost through diet alone, GLP-1 medications may present unique timing factors. The oral semaglutide pill might come in larger doses than the injectable versions in order to make them similarly effective, said Jennifer Lake, pharmacist and assistant professor at Leslie Dan Faculty of Pharmacy at the University of Toronto. “The first thing that people should be aware of is that the weekly injection is a more effective means of weight loss. Hundreds of risky domains and hundreds of thousands of scam messages have been linked to searches for weight-loss drugs. Because these medications affect insulin levels and digestion, they require medical supervision and a valid prescription. Doctors have used them to treat Type 2 diabetes for nearly two decades, and some have also been approved to support weight management. Weight loss with GLP-1 medications like Semaglutide can be the doorway to a healthier life. While the oral pill offers convenience, that may come at the expense of effectiveness, said Dr. Fahad Razak, an internal medicine physician at St. Michael’s Hospital and professor at the University of Toronto, speaking to Global News after the U.S. However, the company warns users to check with their doctor about possible side effects before considering the medication. Around two weeks after FDA approval, the oral Wegovy pill hit the market in the U.S. for the cost of US$149 a month or around US$5 a day. For the past 8 years, she has specialized in men’s health and primary care and is passionate about improving her patient’s quality of life. Yes, but combining the medication with a balanced diet and active lifestyle produces the best and most sustainable results. Other options like oral tirzepatide and orforglipron are in development and may become available soon. A. Pawlowski is a TODAY health reporter focusing on health news and features. The candidates being investigated include MariTide, a drug from Amgen that targets GLP-1 and GIP hormones and is “administered monthly or less frequently,” the company says. "A lot of people are going to like that," Levy says. Still, results vary depending on the specific drug and whether it’s taken orally or by injection. The effectiveness of GLP-1 medications is one of the main reasons they’ve become so popular. Beyond semaglutide and tirzepatide, pharmaceutical companies are testing new oral therapies such as ecnoglutide and orforglipron. Data from SURPASS and SURMOUNT clinical trials show strong early results, with significant reductions in body weight comparable to injectables. Wegovy can be injected at any time of day, just like Ozempic.Unlike many online scams, GLP-1 fraud carries real health risks.When consumers tried to request a refund, the support email bounced back as non-deliverable, according to the BBB.As the New Year sparks renewed interest in diet and health, supermarkets, including Marks & Spencer, Morrisons, Asda, Ocado, and the Co-op, are proactively targeting GLP-1 users.This approach is far safer than searching endlessly for a weight loss doctor near me online without vetting credentials.Based on your medical history, risk factors, and treatment objectives, Ozempic can be suggested by your doctor if you have Type 2 diabetes. The product has been developed to support muscle maintenance and digestive health, and tailored specifically for GLP-1 users who face unique nutrition challenges. Addressing the “fiber gap” — the idea that most people are not eating enough fiber — is already a big consideration in the F&B industry. “Making every bite count” in terms of both nutritional functionality and taste has become increasingly important for people using weight-loss jabs. The rise in GLP-1 use is leading to a sharpened focus on gut health — one which centers on fiber density, prebiotics, protein–fiber balance, while avoiding ultra-processed foods that worsen gastrointestinal symptoms. Recent studies have shown that patients on high-dose semaglutide can lose an average of 15% to 20% of their body weight, a level previously achievable only with bariatric surgery. Originally developed to treat Type 2 diabetes, the drug also provides weight loss benefits, and more Americans than ever are using it for just that. Rybelsus (oral semaglutide) typically produces slightly less weight loss than injectable Ozempic. The notice from the BMS suggests those using both oral HRT and GLP-1s switch to a higher dose or stronger form of progestin to preserve the protection the hormone provides against endometrial cancer. People who don’t want to switch from oral HRT should discuss with their doctor the option of using back-up contraception methods. As far as hormone therapy is concerned, non-oral options include transdermal methods which are absorbed through the skin, like gels or patches, and vaginal methods like rings, creams and inserts. In January 2024, the FDA announced it was evaluating reports of hair loss and suicidal thoughts in patients taking Ozempic, Mounjaro or Wegovy. An earlier trial funded by the company showed people with Type 2 diabetes lost up to 14% of their body weight with the injection at 36 weeks, while those who took the daily pill lost 10%. At the Center for Wellness (CFW), we help patients understand how these medications affect the whole body, including heart and brain protection, kidney health, and even longevity. Although it’s difficult to verify, estimates suggest that ~12% of US adults are currently using a GLP-1 medication for weight loss and/or diabetes combined, which amounts to roughly 31 million people. Clinical studies show patients may lose between 10% to 20% of their body weight over time when GLP-1 is combined with medical supervision.