In 2025, the world of weight loss supplements is more advanced — and confusing — than ever. On the other hand, if you're not interested in supplements or for some reason aren't medically allowed to use them, there are other alternatives you can try adding to your routine to support weight loss and muscle gain. Supplements for weight loss and muscle growth are great additions to a healthy diet and regular exercise, especially if you feel like what you're doing isn't enough. For example, a single dose of 900 mg bitter orange standardized to 6% (54 mg) synephrine significantly increased heart rate as well as systolic and diastolic blood pressure for up to 5 hours compared to placebo in 15 healthy men and women . Some studies indicate that bitter orange and synephrine—as bitter orange extract or pure synephrine—raise blood pressure and heart rate, but other studies show that they do not have these effects 25-27,31,36-39. However, many of the products with these effects contain multiple herbal ingredients, and the role of bitter orange in these adverse effects cannot be isolated. According to all of these reviews, longer term clinical trials with rigorous designs and large samples are needed to determine the value of bitter orange for weight loss. Similarly, a 2011 systematic review of four weight loss trials (including the two described above) concluded that the evidence of efficacy for bitter orange/synephrine is contradictory and weak . The National Center for Complementary and Integrative Health states that chitosan has not been shown to be effective for weight loss.They also affect how your body handles fat and sugar.Most over-the-counter thyroid supplements do not have official dosing rules.The best way to do so is through regular exercise, a clean diet, and additional supplements that support both.We need preregistered, independent head-to-head human trials comparing leading supplements with prescription (injectable) agents under similar behavioral support.As a potent antioxidant, quercetin has been shown to support cardiovascular health, promote healthy immune function, and even enhance physical performance and recovery.One of the key advantages of quercetin supplementation is its ability to support a healthy inflammatory response.Remember, these supplements to lose belly fat are not magic bullets, but they can certainly complement a healthy diet and regular exercise in your fat-loss journey.A 2014 meta-analysis of eight human studies providing 1–3 g glucomannan/day reported a non-significant reduction of 0.5 kg , and a 2021 meta-analysis of eight studies reported a 1.27 kg weight reduction . Belly fat is one of the most stubborn areas of the body to lose, and it often comes with more than just cosmetic concerns. If you are vegetarian or vegan, choosing over the counter or medications for weight loss can be difficult as gelatin is a common ingredient in pill capsules. Weight loss supplements used alone provide nothing more than a Band-Aid to a growing infection. 11 If you recall, this was one of the ingredients originally in Hydroxycut products prior to their ban. How We Chose the Best Weight Loss Supplements for Men But after just a few weeks of incorporating Tea Burn into my daily routine, I’ve experienced remarkable results. As someone who has struggled with shedding those stubborn pounds for years, I was skeptical about trying yet another supplement. The natural ingredients make me feel good about what I’m taking, and they also support my digestion and balance my blood sugar. It offers a convenient method for transforming your body. Within just a few weeks of incorporating ProvaSlim into my daily routine, I started seeing noticeable results. Fiber supplements work by binding to fat molecules, preventing their full absorption and aiding their excretion from the body. Effective appetite suppression is another critical role played by weight loss supplements. Ensuring sufficient vitamin D intake through sunlight exposure, diet, or supplementation can provide comprehensive health benefits beyond just weight management. While fat loss isn’t its primary use, it can help you lose or maintain weight, as it temporarily helps to make you feel satiated. Green coffee extract is well-known for helping people lose weight. While you can consume caffeine to help lose a bit of weight, it still is not a solution for the bigger issue. When you consume caffeine, you not only burn more fat, but you tend to be more active. Select a supplement that aligns with your specific weight loss goals and timeline.During our research, we found that many customers were pleased with this supplement.Look for clinically backed ingredients like BHB ketones (for ketosis support), green tea extract (to boost metabolism), and capsaicin (to enhance fat oxidation).Look for supplements that provide references to scientific studies proving their effectiveness in aiding weight loss.For athletes, third-party testing is paramount to knowing that the fat burning supplement that they’ve chosen does not contain any banned substances.Oakley's path has always been a health-and-wellness-focused one.In a randomized controlled trial, 49 healthy women (mean BMI 25) age 18–50 years were randomized to receive Hoodia gordonii purified extract (2,220 mg/day in two divided doses taken 1 hour before breakfast and dinner) or placebo combined with an ad libitum diet for 15 days . To minimize risk, look for supplements with third-party certifications and transparent labeling. Learn how to optimize your habits with behavioral weight loss science and find the right combination for your needs at this resource. For a deeper dive into the latest findings, explore evidence-based results from top supplements. Ensuring an adequate intake of these micronutrients can create a supportive metabolic environment conducive to effective weight loss. It helps regulate several biochemical reactions in the body and may improve insulin sensitivity, thereby playing a role in weight control. Similarly, B vitamins are essential for energy metabolism, helping the body convert food into usable energy rather than storing it as fat. For instance, Vitamin D has been linked to weight regulation, with research suggesting that adequate levels may support fat metabolism and help prevent obesity. While some supplements may have scientific backing, others lack robust evidence and can even be harmful. Therefore, any decision to include supplements in your regimen should be made under the careful guidance of a healthcare provider. Those include “identifying the root cause of weight gain and addressing it via appropriate dietary and lifestyle modifications.” “Any weight loss supplement should not be viewed as a substitute for the foundational elements of weight loss,” Azzaro says. To date, most of the small clinical trials only show small, statistically non-significant weight loss in overweight adults or adults with obesity. By doing so, it also helps with reducing sugar cravings and leads to weight loss,” says Imus, which studies also show. Deficiencies in vitamin D have been linked to increased fat storage and weight gain. In addition to their role in weight management, probiotics offer numerous other health benefits. Psyllium husk, a popular fiber supplement, is especially effective in promoting digestive health and regularity. Others achieve results when combining a strategic supplement with stress management or consistent sleep schedules.However, tolerance levels vary, so it's important to adjust the intake based on individual sensitivity to avoid side effects like jitteriness or insomnia.Carnosine is made in the body by combining the amino acids beta-alanine and histidine.Lean PM is stimulant-free and can be used with any thermogenic fat burner to further maximize its effects.But in recent years, fish oil supplements have also gained attention as a tool to support weight management.Understanding the role of these vitamins can significantly enhance your weight loss efforts and help you achieve your fitness goals more effectively.It helps the body convert fat into energy, making it a favorite among fitness enthusiasts.When you exercise or play sports, you can quickly lose water weight in the form of sweat. Some research suggests that vitamin D may play a role in weight loss and weight management. Consistently falling short of the amounts of these vitamins your body needs can lead to health problems. “They are involved in immune support, energy production, skin health, and many other vital processes,” says Alyssa Simpson, RDN, a digestive health dietitian in Phoenix. The weight loss industry is rife with pills you can pop that are marketed as boosters to help you shed pounds. While there’s limited scientific research, some studies suggest vitamins may play a role in weight management. Protein can help support feelings of fullness and preserve muscle during a calorie-reduced diet. Learn more about the factors that influence it in our guide on metabolic health in Australia. Always consult your doctor or healthcare provider for personalized guidance regarding your health. This post was written by our team of health writers for informational purposes only and does not constitute medical advice. It combines hormone-balancing herbs, metabolic support ingredients, and a patented botanical (Actiponin) designed to mimic the effects of exercise. VoomVaya MenoSlim Advanced is a menopause-focused weight management supplement formulated specifically for perimenopausal and menopausal women. Many users feel more energized and less fatigued, with some reporting sustained energy throughout the day. Daily essentials may help support comfort and regularity, but they are not a treatment for side effects. You should consult a qualified healthcare professional before making changes. GLP-1 medications drive appetite suppression and weight reduction. The intent is baseline support, not aggressive optimisation or fat loss claims. In this study, researchers followed 18,417 healthy men and 39,740 healthy women enrolled in either the Nurses’ Health Study or the Health Professionals Follow-Up Study. As a result, consumers might not be aware that the presence of certain herbs means that a product contains caffeine and possibly other stimulants . Reported adverse effects include chest pain, headache, anxiety, elevated heart rate, musculoskeletal complaints, ventricular fibrillation, ischemic stroke, myocardial infarction, and death 34,35. The authors of a 2012 review of 23 small human clinical studies involving a total of 360 participants concluded that synephrine increases resting metabolic rate and energy expenditure . The authors noted that the weight gain might have occurred by chance because the trial was insufficiently powered to detect this small difference. Green tea and weight loss have been linked together for years, and multiple studies report that it can be an effective fat burning supplement thanks to its positive relation to increasing energy metabolism, managing diabetes, and promoting cardiovascular health. Thorne packs 250 milligrams of green tea extract in just one capsule of this supplement to help potentially increase your body fat burn. “Of the available information, it appears berberine HCl’s main mechanism for supporting weight loss lies in its effects on gut health and managing your microbiota, similar to some of the best probiotic supplements,” says Chelsea Rae Bourgeois, RDN. In addition to the l-carnitine, you can also find common thermogenic ingredients like green tea extract (200 milligrams) for tackling weight loss on multiple fronts. Look for companies with a proven track record of producing high-quality products and providing excellent customer service. Consult with a healthcare professional if you have any pre-existing medical conditions or are taking medications to ensure the product is safe for your specific circumstances. Choose products that are manufactured in certified facilities following Good Manufacturing Practices (GMP) to ensure quality control and purity. Avoid products with synthetic additives, fillers, or potentially harmful substances. Of course, though, Transparent Labs recommends avoiding Body Recomp servings close to your sleep schedule, as the caffeine counts may influence your ability to rest. This video provides an even more in-depth analysis of the best fat burners for men. Our team, made up of certified personal trainers, wellness experts, and medical professionals, has evaluated 14 different products to date. Here, we’ll cut through the noise a bit, dispelling a few myths on certain supplements and giving alternatives where need be.Moreover, this medication has been linked to improvements in mood and stress management, which can indirectly support weight loss efforts.It also aims to make your gut happier and keep your blood sugar and fat levels in check.By choosing GLP-1 supplements that resonate with your personal wellness goals and values, you can embark on a successful journey toward better health.Many non prescription products contain ingredients with plausible mechanisms.A well-rounded weight loss program can provide some extra help as you work to reach your health goals this year. The top dietary supplements this year include thermogenics, green tea extract, and L-carnitine. Hydroxycut is a brand of dietary supplements that is marketed for weight loss and fat burning. Some of the most researched weight loss supplements include whey protein, green tea extract, caffeine, glucomannan, psyllium fiber, and certain probiotics. Some of the best supplements for weight loss and muscle gain will be a beneficial addition to your already healthy diet and regular exercise regimen, with clean formulas that help promote optimal function of all your body systems while shedding those extra pounds of fat. Many weight loss supplements, like green coffee bean extract and caffeine, boost your metabolic rate via thermogenic mechanisms, which increases fat oxidation and burns more calories. Weight loss supplements function by influencing various physiological processes. Always consider your personal goals, lifestyle, and consult with a healthcare provider before starting a new supplement. See how MCT oil fits into your routine and boost your understanding of boosting metabolism for weight loss. This supplement excels at supporting fat burning while providing a noticeable energy boost. Although magnesium supplements are popular right now for sleep and digestion, the mineral’s benefits for weight loss are dubious at best. It’s not yet known why green tea may be toxic to the liver, so the best thing you can do is be cautious around supplements. While more research is needed to fully understand their weight-loss potential, a meta-analysis of data indicates that probiotics may help with weight loss, as well as a reduction in BMI, waist circumference, and body fat. Always read supplement labels and talk to your doctor before starting anything new. If you are older or have heart problems, your doctor may start you on a lower dose and increase it slowly every 4-6 weeks. Always talk to your doctor before starting any new supplement. Supplements or medicine help restore hormone balance and bring your weight and energy back to normal. Low thyroid hormones slow your metabolism and can cause weight gain. After we vetted all the fat loss supplements for men, this one simply offers the best stack. Easily the best overall natural weight loss supplement out there. LeanBean is the trendiest natural weight loss supplement for women. Probiotics do more than just boost your gut health—they may be a boon to your weight loss efforts, too.6254a4d1642c605c54bf1cab17d50f1e Adding some B-12 supplements to your regular routine could be the key to kicking your metabolism into high gear and shedding that unwanted weight. It has also been shown to be beneficial for men and women, as well as for bodybuilding and aerobic training.(11) If you're not as familiar with creatine, this amino acid can be utilized in supplement form as an ergogenic that can potentially help increase your training capacity, help you retain muscle, and help you recover faster after exercise. Lastly, PhenQ offers its customers a 60-day money-back guarantee, so if you're not seeing the results you desire after the first month, you can return it for a full refund. Using a pre-workout supplement to help give you that extra push to complete your workout is like having a secret weapon. Consistent training, whether in the gym or on the track, is crucial to building muscle and losing weight. Which supplement is best for weight loss? A practical ranking While vitamins can play a beneficial role in supporting weight loss efforts, they are not a stand-alone solution for shedding pounds. Consulting a healthcare professional is recommended before considering chromium supplementation. It is thought to help reduce cravings and promote weight loss, particularly in individuals with insulin resistance. While there is no secret mineral that guarantees weight loss, one mineral that has gained attention in relation to weight management is chromium. If you're struggling to lose weight, several vitamins could potentially be lacking in your diet. Beyond how it makes you feel in the moment, stress can also impact your health. Several foods have the potential to increase cortisol in your body. No supplement is going to lower cortisol immediately. It’s easy to find, inexpensive, and has a number of other health benefits. Magnesium is probably the best supplement to start with if you want to lower cortisol. A good diet and exercise will always be part of the equation but diet pills can be a great tool for consumers. What are the best diet pills for women? There are pills specifically geared towards those who are following a keto diet. A review of ginseng studies didn’t observe any major health concerns. It’s also considered an adaptogen, which are compounds that help protect your body from the effects of stress. Probiotic supplements are usually dosed in colony-forming units (CFU). Probiotics are friendly bacteria and yeast that work with your body to keep you healthy. Propolis may be a little harder to find than the other supplements on this list. Do weight loss supplements actually work? "Vitamin C isn’t just for immunity! It can help reduce fat storage by supporting the body’s ability to metabolize fat."🍊 In general though, a combination of exercise, diet and supplementation seems to work for most people. For example, a weight loss regimen that works for you might not necessarily work for another person and vice versa. Some of these ingredients also come from animal products, such as acetyl l-carnitine, chitosan and conjugated linoleic acid so opting more towards green tea extract, or simply consuming green tea daily, is a safer option for these individuals. There are numerous studies that show positive effects for weight loss when combined with caffeine but there were strong adverse reactions reported which resulted in a ban by the FDA in 2004. 13 Although it can assist with feelings of satiety, fiber overall is not a good supplement for weight loss but rather a healthy addition to a balanced diet that can promote a healthy weight overall. The good news is, there are no known adverse effects to using green tea for weight loss so you can sip away this magnificent green liquid without any worries. Probiotics, which are the live organisms (good bacteria and yeast) that reside in our body naturally and help to keep us healthy are another substance linked to possible weight loss effects. In this study, participants took 4.8 g per day of dried wild bitter gourd powder. Momordica charantia extract seems to increase GLP-1 levels in both animals and people. In human studies, ginseng did seem to improve blood sugar control in people with diabetes, but larger and longer studies are needed. These effects may be related to curcumin’s effect on GLP-1. One small study in people with Type 2 diabetes showed that taking 1,500 mg of curcumin daily reduced weight and blood sugar. Dosage is one 120 mg capsule three times a day with each main meal containing fat (during or up to one hour after the meal). It is intended for use with a reduced-calorie diet and is also indicated to reduce the risk of weight regain. Undigested fat is then passed through the body. It was originally used as a short-term medication to jump-start weight loss, but now newer medical guidelines have added it to long-term therapy. Phentermine is the oldest and most widely used weight loss medication. 9Acetyl l-carnitine is a partial protein that is naturally occurring in our body and animal products. Like a lot of supplements, we are also in the dark when it comes to the long term affects high caffiene intake can have on us. As far as the plant extracts go, there are not enough studies involving humans to prove if they are safe or actually work. If you're a regular bodybuilder or athlete, creatine supplementation should be pretty familiar. Wrecked contains 125 milligrams of caffeine anhydrous, 50 milligrams of slow-release di-caffeine malate, 1,750 milligrams of beta-alanine, and 1,500 milligrams of betaine anhydrous, among other potent ingredients. So, if you're in your bulking phase and aren't skimping on carbohydrates, we believe a weight gainer supplement like Transparent Labs Mass Gainer is one of your best options for obtaining clean mass. TestoPrime is one of the best supplements for muscle growth, as thousands of satisfied customers will confirm. Herbal supplements for weight loss such as carnosine may be of special importance for vegetarian and vegan diets. Some of our top 10 natural supplements for weight loss even have other great benefits, like promoting a healthy liver, normal blood sugar levels, and healthy detox function! Most people have lived with extra body weight at one point in their lives, and know how difficult it is to sustain healthy weight loss. Keep in mind that while these options may be less potent than pharmaceutical weight loss supplements, they come with fewer side effects. They help the body convert food into energy more efficiently, thus promoting fat burning. Well, boosting metabolism and burning belly fat is not just about rigorous exercise and strict dieting. Remember, while there are several good vitamins to lose weight, they should be combined with a balanced diet and regular exercise for optimal results. Additionally, it is an antioxidant that can help protect the body from damage caused by free radicals, which are produced during fat metabolism. Understanding the role of these vitamins can significantly enhance your weight loss efforts and help you achieve your fitness goals more effectively. A similar study published in the International Journal of Obesity Supplements in 2019 focused on efficacy and possible drug interactions of common ingredients used in dietary supplements. Most weight-loss supplements contain such common ingredients as vitamins, minerals, caffeine, fiber, protein, herbs, and other plant compounds purported to burn fat, boost energy, build muscle, lower blood sugar or simply improve nutrition. For the best results, weight loss supplements should be combined with a healthy diet and regular exercise. There are many solutions for weight loss, from intermittent fasting and regular exercise to eating a healthy diet and using supplements. Natural ingredients such as fiber, caffeine, and green tea extract are generally your best, healthiest bets. By enhancing fat metabolism, curbing cravings, and supporting exercise recovery, the right fish oil supplement can help make your weight loss journey smoother and more effective.Well, consider that medications like semaglutide and tirzepatide have shown systemic anti-inflammatory effects and benefits in managing obesity-related conditions.The plant Garcinia Cambogia is green, small, and has the shape of a pumpkin.Fish oil is a dietary supplement containing fatty acids, including omega-3.This mineral carries and delivers oxygen to cells all over the body, and if your exercising muscles can’t get enough oxygen, your exercise performance will suffer, which may impact your weight loss results.Weight-loss supplements can back up women who want to shed pounds, but they work best with healthy living.While research is ongoing for many, user experiences and early studies offer potential insights. Ohio State invests in ending central Ohio food insecurity That’s why people search for supplements to reduce cortisol and to make steady weight loss easier. Lastly, it’s important to remember that fat burners aren’t miracle pills that will automatically shed body weight and stubborn fat for you. While most fat burners will include cayenne pepper, caffeine, and green tea, others may also include extras like HMB or DMAE that can help with things outside of fat burn. As a final note, Bourgeois does stress the importance of speaking to your healthcare professional before subscribing to a green tea supplement regimen. While we include this Berberine HCl powder on our list of best fat burners, we do admit that research is rather limited on its effects on weight loss. Many feel relief without side effects and appreciate that the probiotics also help with gut health. With its patented Actiponin extract and strong customer results, it offers a well-rounded solution for managing menopause-related weight challenges. – Women struggling with menopausal weight gain– Those experiencing cravings, bloating, or glucose imbalance– Women looking for an estrogen-supportive formula– Individuals needing more energy and mood stabilization– Anyone wanting a patented, research-backed botanical for weight loss – Supports weight loss and reduces cravings– Helps balance estrogen levels– Reduces bloating and fluid retention– Improves energy, mood, and overall well-being– Supports relief from hot flashes, night sweats, and brain fog Make informed choices and experience the benefits that the right dietary supplements can bring to your life! Probiotic supplements help create a favorable environment in your digestive tract, improving your body’s ability to process food and maintain a healthy weight. It is crucial to consult a healthcare professional before using weight loss supplements if you have any underlying medical conditions. How Supplements Complement a Balanced Diet and Exercise Plan Interactions may occur during or within 14 days following the use of monoamine oxidase (MAO) inhibitors, sympathomimetics, alcohol, adrenergic neuron-blocking drugs, and possibly some anesthetic agents. Side effects include headache, overstimulation, high blood pressure, insomnia, rapid or irregular heart rate, and tremor. The dose must be increased gradually over 16 to 20 weeks to arrive at the 2.4 mg dosage. The medication’s cost and side effects will also affect the decision. For the best hormone balancing supplements for weight loss, Gaia Herbs offers a gentle, effective solution. The best hormone balancing supplements for weight loss often address estrogen and cravings, and this blend does both. Hum Nutrition Moody Bird is crafted for those facing monthly hormonal swings, and it earns its place among the best hormone balancing supplements for weight loss. Vitamin C supports the synthesis of carnitine, a compound that helps the body burn fat. There are several vitamins and minerals that can help speed up your metabolism and can either directly or indirectly aid in weight loss. These vitamins are not only important to obtain and maintain a healthy weight, but also for overall health. These vegetables are packed with vitamins, minerals, and fibre, making them an excellent choice for anyone looking to lose weight. One of the critical benefits of superfoods is their ability to provide your body with the nutrients it needs to function properly. Stay on top of latest health news from Harvard Medical School. 25 Gut Health Hacks is yours absolutely FREE when you sign up to receive health information from Harvard Medical School. This part of the B vitamins "plays an important role in the metabolism of your fat through your liver," says Keanevey. Adults are advised to get around 15 micrograms of vitamin D per day by the National Institutes of Health. All of these functions ultimately play a role in how efficiently we can lose weight. Vitamins and minerals can be crucial for overall health, assisting in everything from powering our metabolism, falling asleep, healing wounds, building muscle, and maintaining our energy levels. We believe that starts with education, to help all of us understand our always-changing bodies and health needs. Additionally, it contains scientifically proven ingredients that support healthy cholesterol and blood pressure levels within the normal range. Not only did I lose weight, but I also felt more energized and focused throughout the day. Try ProvaSlimAfter years of battling my weight and trying every diet under the sun, I was hesitant to try ProvaSlim. Still, when tested in human clinical trials most products produce modest and variable changes in body weight. Be very cautious when you see weight-loss supplements with tempting claims, such as magic diet pill, melt away fat, and lose weight without diet or exercise. Many weight-loss supplements have ingredients that haven’t been tested in combination with one another, and their combined effects are unknown. Unlike over-the-counter and prescription drugs—which must be approved by FDA before they can be sold—dietary supplements don’t require review or approval by FDA before they are put on the market. It is purported to promote weight loss by binding to some dietary fat in the digestive tract, preventing its absorption 16,41. Overall, the results from clinical trials do not support a clear link between higher calcium intakes and lower body weight, prevention of weight gain, or weight loss. However, the results from clinical trials examining the effects of calcium on body weight have been largely negative. A 2014 randomized crossover trial in 15 healthy young men found that diets high in milk or cheese (supplying a total of 1,700 mg/day calcium) significantly increased fecal fat excretion compared to a control diet that supplied 500 mg calcium/day . Green tea extract is rich in antioxidants known as catechins, particularly EGCG, which may boost metabolism and fat burning. As more people seek alternatives to synthetic weight loss aids, the demand for natural solutions continues to grow. With over 22 years in the field, her extensive experience and dedication to promoting positive dietary habits have made her a trusted voice in the nutrition community. Combining modestly effective ingredients makes sense in theory. Ask whether the monthly cost of a supplement is sustainable. Keep a short symptom log for gastrointestinal effects jitteriness or sleep changes. Many diet supplements claim to promote weight loss, but it’s crucial to approach these claims with caution. When used wisely, weight loss supplements can support your overall health and fitness goals. Certain supplements may aid your weight loss journey by influencing your metabolism or energy levels, but their effects are often modest and will vary from person to person. Clinical studies have shown that caffeine can help burn more calories and enhance physical performance. It also contains a small amount of caffeine, which works synergistically with catechins to enhance fat burning during exercise. It's crucial to approach them with skepticism and conduct thorough research before incorporating them into your weight loss regimen. While these supplements promise a wide range of benefits, their effectiveness can vary significantly. As weight loss journeys can differ significantly from person to person, personalized support is invaluable. Human clinical trials reported around 10.4 percent average weight loss over six months. The question “Which supplement is best for weight loss? Losing 5 percent of body weight often improves blood pressure, blood sugar, and cholesterol. While the best hormone balancing supplements for weight loss are a powerful foundation, pairing them with science-backed strategies can amplify your results. Achieving your goals with the best hormone balancing supplements for weight loss often means expanding your toolkit beyond capsules and powders. While the best hormone balancing supplements for weight loss can be powerful, some situations call for professional input. Figuring out whether these ingredients really help you lose weight safely is complicated, though. Sold in forms such as capsules, tablets, liquids, and powders, some products have dozens of ingredients. The proven ways to lose weight are eating healthful foods, cutting calories, and being physically active. Supplements should never replace a healthy balanced diet, but rather enhance your diet to fill in any gaps. No magic weight-loss tablet can take the place of a good diet and consistent exercise. One 2018 review of 15 well-designed trials found that probiotics, either in foods or in supplements, helped overweight and obese people reduce their body weight and body fat. In both studies, compared to a placebo, some people taking supplements reported small amounts of weight loss. Trimtone is a natural fat burner supplement that uses green tea, fiber and other ingredients to boost metabolism and curb appetite for weight loss support. Vitamin C levels have been shown to be inversely related to body mass. The effect was most noticeable in a study looking at postmenopausal women, which combined vitamin D and calcium supplementation⁵ ⁶. Probiotics have become very popular in the past few years as the importance of the integrity of the gut microbiome for good health has become clearer. We provide well-researched information to help you make the right health decisions. The program now offers eight meal plans to personalize the weight loss journey, including a “freestyle” plan, as well as Mediterranean, protein, keto, vegetarian and one for those on GLP-1s. News in 2025, the WeightWatchers Points Program assigns every food a “Point value” based on calories, protein, added sugar, saturated fat, unsaturated fat and fiber, Michelle Cardel, Ph.D., dietitian and Chief Nutrition Officer at WeightWatchers, tells TODAY.com. Before starting any new weight loss programs, consult your doctor. They’re most effective when combined with lifestyle changes, such as a nutritious diet and routine exercise. Here's an introduction to prescription weight-loss pills. In situations like these, weight-loss medications may be beneficial. High levels of TMAO have been linked to detrimental vascular and inflammatory effects in animal and cell culture studies.It provides clean non jittery energy, focus and appetite control along with fat loss and muscles gain.Secondly, protein fills us up and keeps us satisfied make us feel full and require more work for the body to digest than fast-acting refined carbohydrates.For those aiming to lose or manage fat, maintain liver health, or boost antioxidants, Thorne’s Green Tea Phytosome is a great choice.Evidence shows many OTC ingredients produce small to moderate weight loss—commonly 2–5% of body weight over months—so supplements are best used as adjuncts alongside lifestyle changes and clinician guidance.She is a NASM-Certified Nutrition Coach and an ISSA-Certified Specialist in Exercise Therapy who has spent the last seven years as an editor specializing in health and fitness, working for sites like Bodybuilding.com and Active.com.5 What are common side effects and do they affect your current medications. This suggests that an increased intake of Vitamin C could be beneficial for those aiming to reduce their belly fat. Furthermore, individuals with a higher body mass index (BMI) tend to have lower Vitamin C levels. On the downside, excessive intake of Vitamin C can lead to side effects like diarrhea, nausea, and stomach cramps. Someone actually needs to be harmed by these products and report their experience before they can be removed from the market. Supplements are actually regulated just like food products. There is a lot of research that has been done on the use of different vitamins and minerals in that multivitamin you take but the research on these popular herbs and extracts being thrown into the mix is scarce.1 Human studies show modest but measurable reductions in some stress biomarkers with regular omega-3 intake. Phosphatidylserine appears in human trials mostly as a tool to blunt acute cortisol spikes. In plain language, many people feel calmer and sleep a little better after a few weeks of consistent use. This guide also explains how to choose quality products and how to work with your clinician. A 2011 review and meta-analysis of 12 randomized controlled trials with a total of 706 participants examined the effects of Garcinia cambogia on weight loss . Compared to the placebo group, those receiving Xanthigen lost significantly more body weight by the end of the trial (mean loss of 6.9 kg vs. 1.4 kg for placebo in participants with NAFLD; mean loss of 6.3 kg vs. 1.4 kg for placebo in those without NAFLD). This 16-week trial used Xanthigen, a dietary supplement containing brown seaweed extract and pomegranate-seed oil . Results from laboratory and animal studies suggest that fucoxanthin might promote weight loss by increasing resting energy expenditure and fatty acid oxidation as well as by suppressing adipocyte differentiation and lipid accumulation 125,126. Supplementation with CLA as a free fatty acid (but not as a triacylglycerol) also increased lean body mass compared with placebo. But if you are one of 70% of adults in the U.S. who are overweight and you want to make a change, where do you start? You may notice changes in energy or mood within a few weeks. Choose trusted brands and check your progress with your healthcare provider. It’s eight pills in the day pack, and eight at night. The downside for our tester is the sheer amount of capsules you take each day. “I’ve been taking these for around 20 days, and I’ve seen results from the daytime pills, specifically, with a lot less brain fog and an altogether clearer head,” they said. Lifestyle changes that promote weight loss might also improve mood and energy levels and lower the risk of heart disease, diabetes, and some cancers . The best way to lose weight and keep it off is to follow a sensible approach that incorporates a healthy eating plan, reduced caloric intake, and moderate physical activity under the guidance of a heath care provider. Other ingredients, such as caffeine and bitter orange, could have an additive effect if taken with other stimulants. FDA maintains a webpage listing public notifications about tainted weight-loss products. That degree of fat selective loss is uncommon among oral supplements and it places Motus among the stronger evidence backed non prescription choices. That is important to know because the gap between a small percent of weight loss and a double digit change matters for health benefits. What is the best supplement for rapid weight loss? Have you been tempted by the claims made by weight loss gummies? We are a team of qualified, experienced nutritionists who specialise in weight loss. Sustained commitment to health, diet and lifestyle optimisation is vital. People with complex medical histories should involve their clinician before beginning any new supplement. Stop or consult your clinician if you experience significant side effects, abnormal lab results, or no measurable benefit after a reasonable trial period (commonly three to six months depending on the product). Natural extracts can alter liver enzymes, interact with drugs, or affect blood sugar. When choosing, prefer products where the trial population and design resemble your situation. If you’re ready to take the next step in your fitness journey, add Animal Cuts to your routine today and see the difference for yourself! With 17 active ingredients, it boosts metabolism, energy, and focus while suppressing appetite. Animal Cuts is a comprehensive thermogenic fat burner trusted by athletes for decades. Safe for adults, it works alongside diet and exercise, helping users achieve greater results with minimal impact on cardiovascular and nervous systems. Since caffeine in green tea or GTE may contribute to weight loss, a meta-analysis was conducted on 15 studies comparing green tea/GTE from 583–714 mg/day with caffeine-matched controls. In the U.S., dietary supplements are regulated by the Food and Drug Administration (FDA); however, despite the existence of federal regulatory oversight, the safety of dietary supplement products targeted for weight management support has been questioned . With more than 50,000 dietary supplements on the market, you can just imagine how many of those are marketed as weight-loss products. I am also a registered dietitian, and I have personal experience with obesity and weight loss efforts. Meal replacement shakes are an easy way to potentially reduce your calorie intake to promote weight loss, while still providing your body what it needs. If you have any medical conditions or if you’re taking prescription medications, you should also speak to your doctor before you start using a weight loss supplement. Supplements alone are not a comprehensive approach to healthy weight loss, but they may help enhance weight loss due to other lifestyle changes, such as improved eating and exercise habits. Prebiotics also feed good bacteria in your gut, improving gut health and balance, which research has linked to weight loss success. Green coffee bean extracts (GCBE) are produced from water or alcohol extraction of green coffee beans , and together with yerba mate (Ilex paraguariensis), are considered to be the richest source of chlorogenic acid (CGA) in nature, containing about 6–12% w/w total CGA . For the most part, products marketed for weight management provide EGCG at an amount at or below the proposed EGCG UL for adults when used according to the manufacturers’ instructions. The beneficial effect of green tea/GTE on blood pressure (BP) is supported by several meta-analyses . Studies show that Saxenda can provide significant, sustained weight loss when done along with a healthy lifestyle. Except this means you will most likely want to follow a low-fat diet while taking Alli or you might experience some pretty unpleasant side effects such as upset stomach, bloating, diarrhea and gas. This supplement works by preventing your body from absorbing fat. Alli, a lower dose version of the prescription Orlistat, is the only FDA approved weight loss supplement you can buy over the counter at your local drug store. But make sure that the clinician is one you trust, who’s educated in weight loss (rather than giving unhelpful blanket statements like “lose weight” or “eat less and move more”) and will look at you as an individual. Losing weight takes lifestyle changes and adjustments, and a supplement may be able to support your goals—but it can’t do it alone. After losing weight, everything is more comfortable, being in my body and my clothes. With my Midi care plan, I’m now over halfway towards my weight loss goal! In addition to its weight management benefits, fiber offers several other health advantages. By enhancing satiety and improving digestive health, fiber aids in weight management. Fiber supplements can be particularly useful for those struggling to meet their daily intake. However, addressing and correcting any underlying vitamin deficiencies can support weight management goals and overall well-being. Certain deficiencies, such as vitamin D or vitamin B12, can affect metabolism and energy levels, leading to decreased physical activity and increased fat storage. Additionally, vitamin E acts as an antioxidant, protecting cells from damage and supporting overall health. Furthermore, while over-the-counter dietary supplements are widely used for weight loss, evidence to support their safety and effectiveness is at times limited and often controversial. For questions regarding dietary supplements or weight loss aids, Parkview Outpatient Pharmacies are here to help. While some dietary supplements may help with weight loss, they often only provide a small effect, especially in the absence of lifestyle changes. Many popular dietary supplements lack substantial evidence for their effectiveness in weight loss. Among the countless dietary supplements available, there are some that have data supporting their potential benefits for weight loss. Even protein works best in conjunction with resistance training to ensure the weight you lose is fat, not muscle. The majority of your weight loss will come from your consistent calorie deficit and exercise regime. Supplements are a tool, not a cure, and they typically result in modest, incremental weight loss benefits. Omega-3 fatty acids, specifically EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are essential fats with widespread health benefits. While the effects are modest, WKBE can be a useful tool for supporting a calorie-controlled diet, particularly when eaten with carbohydrate-rich meals. Increase your intake of lean protein, fiber-rich fruits and vegetables, magnesium, and probiotics to support digestion and overall health. Begin by cutting processed foods and added sugars from your diet. Honest comparisons often highlight the most trusted products on the market. Prioritize products that have undergone third-party testing for quality and safety. Monitor side effects and progress over at least three to six months. Start with the lowest reasonable dose and combine the supplement with structured nutrition, resistance training, and behavior support. Talk with a clinician before starting any supplement, especially if you take other medications. Combine any supplement with protein, resistance training, sleep, and behavior support. Imagine two people with similar starting weights and routines. That said, some supplements can fill nutritional gaps when you’re in a calorie deficit as well as help with appetite control. In the long run, it’ll save you money since you won’t be spending it on supplements you don’t need. Products that claim to “melt fat” or result in “30 pounds lost in 30 days” are likely predatory. Dietary fiber is found in fruits, vegetables, whole grains, and legumes and is very beneficial when you’re backed up—but can they help with weight loss as well (19)? Testosterone can reduce fat mass and increase lean body mass, which is attributed to the study’s results (18). It seems that Garcinia may be effective for weight loss, but the evidence is mixed. When EGCG inhibits this enzyme, norepinephrine increases in your body, which is thought to promote fat breakdown (3). It might also help you burn stored fat, which can help you lose weight. Both extracts work together to keep fat cells from multiplying. When looking for affordable supplements, try brands such as MagixLabs, SR, and Nature’s Craft. Garcinia cambogia extract is an excellent choice for the best diet pills. Green tea extract is derived from the leaves of the Camellia sinensis plant. Fiber plays a significant role in digestion and can aid in weight management by promoting feelings of fullness. Rich in catechins, particularly epigallocatechin gallate (EGCG), this supplement is known for its antioxidant properties and ability to enhance metabolism. Additionally, the reduction in fat absorption has been linked to improvements in metabolic markers such as triglycerides and cholesterol levels.