But they may help you make the lifestyle changes that you need to practice to lose weight and improve your health. Weight-loss drugs aren't an easy answer to weight loss. Phentermine by itself (Adipex-P, Lomaira) also is used for weight loss. You need to follow a low-fat diet when taking this medicine. It affects the way your body absorbs fat. But practicing healthy lifestyle habits may help limit weight gain. Have you tried diet and exercise but haven't been able to lose enough weight? Dive into expertly crafted content on supplements, longevity, and optimizing your mind and body for peak performance. By staying informed and cautious you can make better choices that support your weight loss journey effectively and safely. These findings suggest a reduction in the risk for cardiovascular complications in diabetic patients after guar gum supplementation.While the majority of weight loss supplements come in unsweetened pill form, some powders use calorie-free sweeteners, which may come from artificial sources.Just make sure that whatever you're adding to your daily regimen is clean and free of inflammatory ingredients or sugars, and you're actually noticing results after a few months of consistent use.If you’re confident in the research, this could be a cheap, affordable weight loss supplement that can be easily added to your daily regimen.A double-blind, randomized, placebo-controlled trial reported that curcumin administration is well-tolerated and can positively influence weight management in overweight people by increasing weight loss (from 1.88% to 4.91%), and reducing body fat percentage (from 0.70% to 8.43%) .Of adults attempting weight-loss, 33.9% report using dietary supplements; these estimates are higher in younger adults, women, and in lower socioeconomic groups (20,21).(9) Maintaining and building muscle helps with weight loss, as muscle mass burns more calories than fat.This red chili pepper extract has been shown to aid in light appetite control and can increase the body’s metabolic rate. This formulation is available with or without caffeine, but we’re focusing on the caffeine-free variety for this particular review. Legion's Phoenix comes with an extra absorbable form of synephrine and a high dosage of EGCG to promote its fat-burning properties. If you’d rather take a single serving of fat burner capsules, we suggest looking at something like Legion Phoenix Fat Burner Without Stimulants. (5) “Of course, though, if you’re sensitive to caffeine, this dosage may leave you feeling jittery,” notes Bourgeois, who rates the formulation at 3.5 out of 5. For those who want a thermogenic fat burner, we recommend Jacked Factory BURN-XT. Guar gum is a dietary fiber derived from seeds of the Cyamopsis tetragonolobus plant, and is an ingredient in some food products, used as an emulsifier and thickener in baked goods. Of the trials noting low risk of bias, two studies reported significant weight loss (ranging from −1.3 kg to −3.6 kg) (79,80) whereas, the other two were non-significant (81,82) (see Tables S9A–D). The plant ephedra sinica’s main proposed active ingredient for weight loss is ephedrine which is often taken is conjugation with caffeine. Our weight loss product review wouldn't be complete without a mention of MuscleTech's Hydroxycut.But they may help you make the lifestyle changes that you need to practice to lose weight and improve your health.While previously mentioned, it’s worth repeating that before starting any new supplements, have a detailed conversation with your healthcare professional if you have a pre-existing health condition.“Improved blood flow can help you make the most of your workouts, supporting weight loss efforts.Vitamin B12 may help with weight loss, but the research is mixed, like many others on this list.Here’s what the science says about weight loss supplements that may be worth your time and money. How should I choose the right weight loss supplement for my needs? But a healthy weight takes more than just an injection or pill, research shows — it requires a comprehensive treatment plan that leads to real changes in our daily activities so we can keep the pounds off for good. Evidence-based research suggests that while some products can be effective, their impact is often modest and should be complemented with a balanced diet and regular exercise. Weight loss supplements are not a substitute for a balanced diet and physical activity. Check for a Natural Product Number (NPN) and consult your healthcare provider before using any supplements. By making informed decisions, you can enhance your weight loss efforts while protecting your overall health and well-being. Many weight loss supplements promise quick fixes and miraculous results. If you’re feeling a bit weary about weight loss supplements, there are safer alternatives you can try. It can get pretty tricky regarding the safety of weight loss supplements. An animal study revealed that rats on a high-fat diet who were given B vitamins experienced weight loss and saw an increase in enzyme activity that influenced metabolism (25). While supplements may aid in boosting metabolism, reducing appetite, or increasing fat burning, they are not a substitute for sustainable lifestyle changes. Remember that no supplement can replace the benefits of a healthy diet and regular exercise. Natural weight loss supplements can be a helpful addition to your weight management plan if chosen wisely and used responsibly. First, supplementation with CLA was shown to decrease the size of adipocytes, alter adipocyte differentiation, stimulate apoptotic pathways, and regulate lipid metabolism . Several possible mechanisms have been suggested possibly aiding weight loss in animal models and human subjects. CLA is GRAS (generally recognized as safe) in the United States since 2008 , with no major side effects reported in several studies except for the appearance of occasional GI complaints . The CLA content of food products is highly dependent on various factors, such as the type of feed 247,248, species and age of the animal , the rumen pH and the time of the year . Caffeine has been used as an approach in weight management because of its ability to stimulate both noradrenaline and dopamine secretions, which, in turn, may decrease BW and body fat (BF), as well as increase thermogenesis in brown adipose tissue via an unknown mechanism(s) . Responses are variable and likely depend on individual sensitivity to caffeine, the existence of co-morbidities, and intake of concomitant medications or supplements . Small amounts of caffeine can pass from the mother to the infant through breast milk, but a review of the evidence indicated that consumption of ≤300 mg/day (equivalent to about 2–3 cups of coffee) by the mother does not adversely affect the infant . Limited new data were identified for children (3–12 years old) and adolescents (12–19 years old), and the authors indicated that “there is no evidence to suggest a need for a change from the recommendation of 2.5 mg/kg caffeine/day” . Many diet supplements claim to promote weight loss, but it’s crucial to approach these claims with caution. The effectiveness of weight loss supplements varies widely, with some showing modest benefits while others lack solid scientific backing. When exploring diet supplements, you’ll often encounter labels like “natural” or “synthetic.” Natural supplements are usually derived from plant-based ingredients, such as green tea or fiber supplements. If you have conditions like high blood pressure, heart disease, or insulin resistance, you need to be particularly cautious when considering weight loss supplements. Focus on a balanced diet rich in whole foods, including fruits, vegetables, lean proteins, and healthy fats. Aside from thoroughly energizing your body, this supplement is an excellent source to help in metabolizing fat stores. Leanbean further enhances fat reduction by stimulating your body's metabolism. Some of the top ingredients to help with weight loss and overall wellness are listed below. Choose ForestLeaf Berberine Supplement for a simple, natural way to support your weight management and energy needs.This guide explores the best weight loss supplements, their benefits, potential side effects, and tips on choosing the right ones for your needs.If you’re willing to spend a little extra money, you can snag one of these products with a more robust ingredient list.With a background in surgical oncology and expertise in nutrition and exercise physiology, Dr. Attia is committed to helping individuals extend both lifespan and health span.Caffeine appears to suppress hunger and stimulate energy expenditure (EE) through increased excitability of the sympathetic nervous system (SNS), increased fat oxidation and Brown Adipose Tissue activation 137,138.Trimtone is formulated for women, so men looking for the best weight-loss supplements should try PrimeShred instead.First and foremost, you’ll want to consider the type of potential fat burn you are looking for.Taneia Surles, MPH, is a health and wellness writer, editor, and public health professional. It contains ingredients like caffeine, capsimax powder, and nopal, which help suppress appetite, boost energy, and enhance fat oxidation. Whether you need appetite control, increased energy, or enhanced fat burning, there are supplements tailored to your needs. These supplements can enhance fat oxidation and energy expenditure during exercise. Know what claims about weight loss mean Maybe you tried a juice cleanse, diet tea, or supplement that literally said it would “melt fat”. A lot of over-the-counter supplements do not provide adequate research on safety and effectiveness of their use and some prescription medications are not safe for those with certain conditions or provide unfavorable side effects. Although diet and exercise is still the number one recommended way to lose weight and keep it off, that does not make it any easier. Some of these ingredients also come from animal products, such as acetyl l-carnitine, chitosan and conjugated linoleic acid so opting more towards green tea extract, or simply consuming green tea daily, is a safer option for these individuals. Others, such as Hoodia and Ephedra Sinica, are substances not normally found in the diet therefore safety with use of these supplements is a concern. Our list features various supplement types, including protein powders, greens powders, and pre-workouts, with prices typically ranging from $0.50 to $5.00 per serving. “Legion Triton Fish Oil contains evidence-based doses of EPA and DHA and an impressive dose of vitamin E. Packed with omega-3 fatty acids, it helps reduce inflammation, lower triglycerides, and protect against cognitive decline. A high-potency, molecularly distilled fish oil with additional vitamin E and lemon oil, this supplement from Legion meets stringent purity standards and is sourced from sustainable fisheries. But the female supplement-takers reported feeling less hungry, said lead author Angelo Tremblay, Ph.D., an obesity researcher at Laval University in Quebec City. Methionine, Inositol, and Choline are the three ingredients which form MIC. Medical clinics which specialize in lipotropic nutrients can create a specific formula, also known as MIC Combo, which has proven to be an effective aid in total fat loss. Horizon Weight Loss consulted our pharmacy to develop MIC-Lipo capsules based on our observation of current weight-loss protocols which include MIC-Lipo treatments. For the most part, products marketed for weight management provide EGCG at an amount at or below the proposed EGCG UL for adults when used according to the manufacturers’ instructions. Undesirable effects of GTE consumption reported in clinical trials are largely GI-related tolerance issues; however, hepatotoxicity concerns have led to a proposed UL of 300 mg/day of purified EGCG. Current evidence suggests that GTE may be beneficial for weight management, glucose regulation, and reducing TC and LDL-C as well as BP in people who are overweight or obese. Some studies have suggested that fucoxanthin may have some anti-obesity effects, but more research is needed. We had to give this product a 3 out of 5 for dosage convenience, as you do have to keep the supplement handy multiple times per day. Unfortunately, the dosage isn’t the most convenient when it comes to promoting effective weight loss outright. A search of the Mintel GNPD revealed many weight management supplements containing GCBE ranging between 50–3996 mg/day. Thus, the overall evidence supports the benefits of green tea/GTE on BP in the general population and overweight/obese individuals at increased risk for CVD. A recent meta-analysis with 24 studies providing 208–1344 mg catechins/day showed that green tea/GTE reduced systolic BP (SBP) and diastolic BP (DBP) independent of caffeine content . Another meta-analysis of 17 studies showed that green tea/GTE significantly reduced FBG and HbA1c, especially at ≥457 mg/day, regardless of supplementation duration . Moreover, a meta-analysis of green tea or GTE supplementation of four clinical studies with subjects having non-alcoholic fatty liver (NAFLD) reported a decrease in BMI of −2.08 kg/m2 (95% CI, −2.81 to −1.36) . U.S. News & World Report 2025 Best Diet rankings If you plan to exercise within an hour after breakfast, eat a light meal. If you don't eat, you might feel slow-moving or lightheaded when you exercise. Studies suggest that eating or drinking carbohydrates before exercise can help you do better during your workout. Much to our dismay, studies on caffeine did not show any promising results for weight loss but there was some improvement when it was combined with the catechins in green tea. There is research available for some of these substances supporting weight loss claims, such as green tea extract and acetyl l-carnitine however, research on this combination of ingredients has not been done which is a red flag for safety. Let’s take a look at some of the over-the-counter weight loss supplements on the market. What protein is best for weight loss and muscle gain? By following these precautions, you can minimise risks and enjoy the benefits of weight loss supplements confidently. These benefits make weight loss supplements a valuable addition to your regimen, especially when combined with a balanced lifestyle. Natural supplements suit those seeking gradual, sustainable weight loss, while pharmaceutical options are better for individuals needing more intensive support. When it comes to purchasing weight loss supplements, reputable online retailers offer convenience and a wide selection. Next, we'll explore where to find high-quality supplements to support your weight loss journey. Protein supplements are vital for supporting muscle mass, especially during weight loss. Consuming green tea extract as part of a balanced diet and exercise regimen can yield effective weight loss results. Rather, they serve as supplemental assistance to an established weight loss plan which includes consuming an array of the most nutrient-dense foods alongside proper sleep etiquette and exercise. Chelsea Rae Bourgeois, RDN rates the formulation at 4 out of 5, stating, “The lone ingredient is green tea phytosome, and I’m happy that there’s multiple studies to support its use as a thermogenic for supporting weight loss.” In your weight loss journey, it’s always important to remember what a healthy weight is for you based on your body mass index. They work through different mechanisms such as appetite suppression, fat burning, metabolism-boosting, and nutrient absorption inhibition. Weight loss is a common goal for many individuals looking to improve their health, boost their energy, and achieve their desired body shape. At the same time, L-Tyrosine is a vital amino acid that supports metabolism and helps elevate your mood while reducing fatigue when cutting calories. Losing weight can be challenging as various fad diets and exercise equipment often divert us from the right path. When you hear metabolism, you might think of food breaking down into bits for energy. The day formula ignites your metabolism and fuels your energy, empowering you to crush your fitness goals. Best Protein Powder When it comes to eating and exercise, everyone is different.A large trial found that a once-weekly injection of semaglutide,, along with diet and exercise, resulted in a weight reduction of around 15% after 68 weeks (15).This certification is given to products that are organic, non-GMO, and made with easy-to-absorb ingredients.The main compounds are mangostins and isoprenylated xanthones, exerting antioxidant effects .This may contribute to insulin resistance and block weight loss.Funding sources were not revealed for 9 studies; the remaining were funded by a combination of local government and industry sponsorship.Lately, those of us who want help losing weight have more options than ever before.Inulin is also used as a fat and sugar replacement and texture modifier in many bakery, dairy and meat products .It is essential, whether taking a prescription or an over-the-counter weight loss supplement, to talk to your doctor and make sure you have all the facts. This guide will help you navigate the complex world of weight loss supplements, covering everything from how they work to the risks and benefits, so you can make the best choices for your health. While weight loss supplements can provide valuable support, it’s essential to have realistic expectations. While weight loss supplements can be effective, they may also come with potential side effects. It’s effective in reducing calorie intake and supporting weight loss when combined with a healthy diet. These supplements can lead to significant weight loss when combined with a low-fat diet. Kelly Clarkson achieved her weight loss goal through healthy lifestyle changes. A balanced diet rich in vitamins, combined with an exercise routine, is crucial for overall health and weight management. It’s among the best natural supplements for weight loss if you prefer an herbal option. Trimtone is the best weight loss supplement for women who plan to accelerate their weight loss journey by boosting their metabolism. If you take a fat burner with caffeine too late in the day, it could potentially mess with your sleep. Though you can take your fat burner when you wake up in the morning to jumpstart your metabolism and reap its potential health benefits, many people choose to take their fat burners before they work out. As we discussed, fat burners use ingredients that may help with fat oxidation, thermogenesis, and appetite suppression. “Vitamin D levels have been linked to body mass index (BMI), indicating that vitamin D supplementation may support weight management efforts,” says Chelsea Rae Bourgeois, MS, RDN, LD.From appetite suppressants to metabolism boosters and fat blockers, knowing the various types can help you make informed choices.Look for supplements containing ingredients that have been scientifically validated.Carnitine also supports cognitive function and has potential neuroprotective effects, making it beneficial for brain health.Certain supplements may aid your weight loss journey by influencing your metabolism or energy levels, but their effects are often modest and will vary from person to person.Being transparent about your supplement use allows your healthcare professional to adjust your treatment plan if needed, ensuring your safety throughout your weight loss journey. FDA approved supplements Pyruvate is a product of glycolysis, the first step in the breakdown of glucose to produce energy, and a key intermediate of several metabolic pathways in the cell. The one high quality (low risk of bias study) did not demonstrate significant changes in weight between groups at follow-up (116) (see Tables S15A–D). Three studies demonstrated significant differences between arms, and the remaining did not report on significance. All studies were published in the USA, three were industry funded (two not reported), and the number of participants ranged from 7 to 51. Study duration ranged from 30 days to 24 weeks and the number of participants in each arm ranged from 12 to 62 subjects. It’s strongly affected and influenced by dietary factors, which can then impact energy balance and weight gain.This mechanism helps reduce overall fat intake, thus facilitating weight management.Naturally, most people lose sight of their goal when they struggle to drop weight or experience a weight loss plateau.It's critical to mention it's also necessary to carry out a full fitness program while using weight loss supplements.Chitosan is used medically to decrease bleeding for wound dressings and has been proposed, due to its ability to bind to lipids and decrease their absorption in the gastrointestinal tract, to lower cholesterol and body weight (52,53).The main antioxidant in green tea extract, epigallocatechin gallate (EGCG), may boost metabolism (2).If you have any existing medical conditions or are taking any prescription medications, it’s essential to speak to your doctor before you start taking a weight loss supplement. But what if we don’t qualify to take prescription weight loss supplements? Unfortunately, it is more expensive than other prescription weight loss supplements on the market, such as Orlistat, which is relatively inexpensive in comparison. Let’s take a look at some of the FDA-approved weight loss supplements on the market. The FDA has approved a small handful of weight loss supplements as medications but, in most cases, you have to qualify to get a prescription which is not always an easy feat. During menopause, when estrogen and progesterone naturally drop, some women may notice an increase in weight and excess stomach fat. Our top pick for gut health support, Gainful Fiber, offers a simple ingredient list that can help keep you regular. When following a weight-loss regimen, it can be easy for the quality of your diet to suffer. Vera has been shown to reduce visceral fat accumulation, suppress lipogenesis related genes , enhance the expression of UCP-2 and activate the AMPK pathway, leading to the acceleration of glucose and lipid oxidation in muscle and white adipose tissue . Moreover, some works suggested greater activation of PPAR-γ receptors and pro-inflammatory cytokines 246,253, fatty acids oxidation , and the browning of white adipose tissue as a mechanism of fat mobilization 259,260. Moreover, its supplementation led to decreased adipogenesis and viability in preadipocytes and increased lipolysis and reduced lipogenesis in mature adipocytes . If you’re looking for a non-prescription weight loss aid that works with your healthy lifestyle, alli is a smart choice. Alli is an FDA-approved weight loss aid that blocks about 25% of dietary fat from being absorbed. With a focus on optimizing mitochondrial function, Mitolyn helps your body burn fat more efficiently and provides the energy you need for active days and effective workouts. Looking for a natural way to support your weight loss journey and boost your daily energy? Mitolyn is designed to support natural energy production and weight management by targeting cellular health. The effectiveness of natural weight loss supplements can vary with each user. We recommend stimulant-free weight loss supplements like CalmLean instead. Combine regular cardiovascular exercise, strength training, healthy eating, and stress management for effective fat reduction throughout the body, including the belly region. Some individuals may opt to increase their intake of weight loss supplements to accelerate their weight loss journey. Others may help stabilize blood sugar levels, which can reduce cravings and help you feel fuller longer, making it easier to stick to a healthy eating plan. But they can be supportive tools when integrated into a well-rounded weight management plan. Consulting with your healthcare provider ensures that any supplement you consider is safe and suitable for your health needs. Subtilis (found in Align brand supplements) lost up to 15.6 pounds in a month—far more than those given a placebo supplement. While researchers are still working to pinpoint which strains of probiotics are best for weight loss and type-2 diabetes, early results are promising. Obesity is defined by the World Health Organization as a condition of fat excess, rather than as a simple increase in BMI.“Previously, I was using Optimum Nutrition Gold Standard Pre-Workout, but I would say the energy boost and focus I’ve gotten from LEAN has been more noticeable,” she says.Regarding weight loss, omega-3 fatty acids may enhance fat burning, boost metabolism, and improve satiety to help curb cravings.Based on the results seen thus far in this study, Plenity can potentially improve various aspects of body weight for at least 24 weeks.The Rockstar brand offers natural and high-quality dietary supplements for trainers, pro athletes, and fitness lovers everywhere.Although P. ginseng has been shown to exert anti-obesity effects in several animal studies, there have been relatively few studies investigating its effects in humans.If not utilized by activity, this can put you at risk for developing certain health conditions such as hyperlipidemia, hyperglycemia and lipodystrophy. These are, without a doubt, the cornerstones of any successful weight management journey. Its carefully crafted formula delivers a trifecta of benefits, boosting your basal metabolic rate, curbing those pesky hunger cravings, and sharpening your energy and focus. It includes well-studied appetite suppressants like yerba mate and damiana to help you rein in those pesky cravings and stick to your plan. That said, another user bluntly described it as a supplement that “does absolutely nothing and costs a fortune” . Additionally, consider combining vitamin B12 with a comprehensive B-complex supplement to further support energy metabolism and overall well-being. At the heart of turmeric's therapeutic properties is the compound curcumin, a potent antioxidant and anti-inflammatory agent.For individuals seeking to support joint health and mobility, turmeric supplements can be a valuable addition to their daily routine. As a potent antioxidant, quercetin has been shown to support cardiovascular health, promote healthy immune function, and even enhance physical performance and recovery.One of the key advantages of quercetin supplementation is its ability to support a healthy inflammatory response. From energy production and metabolism to neurological health and red blood cell formation, these water-soluble vitamins play a crucial role in maintaining optimal bodily function.Individuals who are under chronic stress, follow a vegan or vegetarian diet, or have certain medical conditions may be at an increased risk of B vitamin deficiencies. Probiotic supplements containing strains like Lactobacillus and Bifidobacterium have been shown to promote a balanced gut flora, enhance immune defenses, and even aid in weight management efforts.Complementing probiotic supplementation, fiber-rich supplements can also contribute to optimal gut health. Some studies find that consuming a higher than usual amount of protein in your diet may offer benefits.Published studies are of small sample sizes, short study follow-up, poor study design, and often lead to inconsistent conclusions and results reporting.Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.Our evaluation highlights the importance of the efforts put forth by the Office of Dietary Supplements to advance the science of nutritional supplementation and a need for high-quality research.Results are based on the opinion of the author and their own rankings and do not necessarily reflect typical results from the use of these products.By choosing one of the best supplements for weight loss, you can enhance your efforts and achieve your goals faster.Any weight loss of more than a pound per week over a long period of time is unusual and should be monitored by a doctor.Beyond how effective a drug or supplement is, we also need to consider what we can afford, personal preferences (like pills over injections) and if we can live with potential side effects. Below are some potential effects that could come from adding a fat burner supplement to your normal routine. “The research has shown that green tea extract may offer many benefits for the average healthy adult,” according to Chelsea Rae Bourgeois, RDN, who rates this formula at 4 out of 5. “…L-carnitine may support the body’s biological processes to reduce fatigue during your workout and efficiently utilize fatty acids,” says Chelsea Rae Bourgeois, RDN. If you’re looking for a single-dose per day, we suggest looking at a fat burner supplement like Legion Phoenix. “Show Me the Greens Powder aims to support a healthy gut.” That support comes from the fiber-rich prebiotic blend, which nourishes beneficial gut bacteria. “The GI microbiome may be a major factor affecting energy balance and metabolism, ultimately contributing to weight management efforts,” she says. Efforts to lose weight should not come with unwanted side effects, so if you’re sensitive to caffeine, you might search for a different pre-workout.” “Improved blood flow can help you make the most of your workouts, supporting weight loss efforts. LeanBean is formulated using all-natural ingredients with a great combination of fat burners and appetite suppressants. Caffeine is an incredibly powerful weight loss supplement, when used judiciously – too much can cause jitters and sleeplessness. When 18 separate studies were reviewed, the average weight loss for subjects taking CLA amounted to 0.2 pounds weekly over a six-month period. Unroasted coffee beans contain chlorogenic acid and caffeine, both of which can help with weight loss (4, 5). This supplement contains natural ingredients, such as capsimax powder, chromium picolinate, caffeine, nopal, and L-carnitine furmarate. Moreover, grapefruit may alter the metabolism of several drugs through cytochrome P450 interactions . It should also be highlighted that different results may be seen if grapefruit is consumed in different quantities and modalities, taking into account that the included studies only investigated grapefruit or grapefruit juice as a preload before meals. Naringin and hesperidin are also able to improve glycemic control, enhancing insulin secretion and inhibiting gluconeogenesis ; like many other polyphenols, naringin has also been reported to stimulate the AMPK pathway, thus enhancing fatty acid oxidation and inhibiting lipogenesis . These results may also indicate that flaxseed supplementation has a cumulative and time dependent effect, probably because ALA, lignans or other flaxseed components build up their concentration in tissues over time or because of gut microbiota adaptations happening over a longer period. Vera supplementation was able to decrease serum triglycerides, total cholesterol, LDL, and fasting blood glucose level, as well as reducing HbA1c and insulin levels . In the relentless pursuit of vibrant health and wellness, individuals often find themselves navigating the vast landscape of dietary supplements. If you want to get more sophisticated you can opt for a natural weight loss supplement like forskolin, which uses a different mechanism to stimulate your satiety (the opposite of appetite). This can help people with a stubborn metabolism lose more weight than had they just tried diet and exercise alone. PhenQ is a simple and focused weight loss supplement that uses caffeine, carnitine, and capsicum for maximum efficacy. L-Carnitine is naturally produced in your body anyway, but a review of 37 studies showed supplements significantly reduced fat mass and body weight.These findings suggest that inulin may be able to reduce daily caloric intake possibly promoting fullness and reducing hunger and may therefore be beneficial when food intake is not restricted.Some on social media have called berberine “nature’s Ozempic,” and questions like “what’s the best time to take berberine for weight loss” are regularly asked.Combine regular cardiovascular exercise, strength training, healthy eating, and stress management for effective fat reduction throughout the body, including the belly region.You work with a “lifestyle coach” and have peer support to motivate you.Since protein has calories, consuming too much can make it harder to lose weight.Nevertheless, these observations are not supported by the results of another meta-analysis that found a non-significant reduction in BW of −0.19 kg , although a limitation of this study is the heterogeneity of the interventions, which include capsaicin supplements and hot pepper foods. Conjugated Linoleic Acid (CLA) is a fatty acid found in animal products that may help with weight management. L-carnitine is a compound naturally found in the body that helps transport fatty acids into mitochondria, where they’re converted into energy. Green tea extract is another supplement backed by dietitians for its role in weight management. Discover the best fibre supplements in Australia to improve digestion and promote weight management. Research suggests that adding just 4 grams of fibre to your daily diet may lead to a 3.25-pound weight loss over six months. So, get ready to discover the game-changing supplements that could revolutionize your weight loss efforts in 2025 and beyond! OLLY Metabolism Gummy Rings are a great choice for anyone looking to support their metabolism, energy, and digestive health in a simple, enjoyable way. Looking for a simple and tasty way to support your metabolism and energy every day? Deliciously apple-flavoured, gluten-free, and easy to take daily, these gummies provide a convenient way to support healthy weight management and vitality. With 17 active ingredients, it boosts metabolism, energy, and focus while suppressing appetite. It’s also essential to understand the difference between natural and synthetic supplements to choose products that best suit your needs while ensuring safety and effectiveness. From appetite suppressants to metabolism boosters and fat blockers, knowing the various types can help you make informed choices. Weight loss supplements come in many forms, each designed to target different aspects of weight management. For example, some supplements may slightly boost energy expenditure, helping you maximize your workout sessions. European research found that pairing a 600-mg dose of ALA with metformin doubled the loss of body fat compared to metformin alone. Today, studies show its active ingredient—the antioxidant curcumin—is increasingly linked to anti-diabetes and anti-obesity prosperities. Always consult with healthcare professionals before starting any new supplement to ensure it aligns with your health needs and goals. Supplements alone won’t lead to dramatic weight loss. It prevents the absorption of dietary fats, leading to reduced calorie intake. One of the major obstacles to weight maintenance is the decreased satiety that derives from weight loss and hypocaloric diets. A recent review analyzing 12 RCTs from 2013 to 2015 described positive effects of 10 gr inulin or FOS-enriched inulin on weight reduction, satiety, and daily energy intake, mostly in patients with T2D, in addition to greater reductions in Hba1c and other metabolic syndrome related parameters . These results suggest that, although guar gum can lower cholesterol levels and improve insulin sensitivity compared with placebo , it seems not to be effective in lowering body weight and it should therefore be administered together with appropriate dietary manipulation. Noteworthy, a prospective, non-randomized controlled trial suggested a possible beneficial role of glucomannan on weight loss in overweight subjects treated with a combination of Garcinia Cambogia and glucomannan at a dosage of 500 mg, twice a day, for six months. According to Keithley et al., glucomannan administration at doses of 2–4 g per day resulted in significant weight loss in overweight and obese individuals . The fat oxidizers in particular that you’ll find in a good weight loss pill can push your weight loss beyond what you’d get with diet and exercise alone. PhenQ’s combination of chromium, niacin, carnitine, and caffeine helps men keep their fat oxidation rates high and their appetite under control, while also sustaining high energy levels throughout the day. While a lot of weight loss pills rely on heavy doses of stimulants like caffeine to keep your metabolism high throughout the day, these leave you high and dry at night. In a weight loss supplement, that raised metabolism is what we’re after, as that will help you burn more fat faster. (9) Plus, the fact that PhenQ is only two pills per day and the company provides a month’s supply (60 pills) in each bottle earns it a 4 out of 5 for dosage convenience. Caffeine works by stimulating your central nervous system, which increases your body heat and burns extra calories. Each two-pill dose of PhenQ contains 150 milligrams of caffeine. Use alongside a sensible diet and training, and manage stimulant timing to avoid disruption. However, some active ingredients appear underdosed compared to clinical benchmarks. “The price is pretty good for what you’re getting, but it’s not the cheapest fat burner on the market,” says Nick English, BarBend expert reviewer. “If you’re sensitive to caffeine, the multiple doses of caffeine may not be ideal for you.” So, for those who like to train in the evening, this pick may not be ideal. Considering you have to take multiple doses per day, though, that makes sense. “I’m usually hesitant with fat burners, but I appreciate that Recomp has been tested by a third party,” according to Chelsea Rae Bourgeois, RDN, who rates the formulation at 3.5 out of 5. But paired with a calorie deficit and exercise routine, they may be able to help encourage your progress. She notes that a robust maintenance plan equips individuals with the strategies and support needed (such as coaching or peer-to-peer and group support) to keep the weight off for the long term, preventing weight regain and ensuring lasting success. “A comprehensive weight loss program aims not just for weight loss, but for sustainable weight management,” Mok says. The program should be led by trained and certified obesity medicine providers — not just people calling themselves "weight loss experts," McGowan advises. Capsaicinoids may also affect food intake, and a meta-analysis of eight studies showed that capsaicinoid ingestion with a minimum dose of 2 mg before a meal significantly decreased ad libitum calorie (−74.0 kcal) during the meal, suggesting an appetite suppression effect . For example, a meta-analysis of nine studies with different durations and amounts showed that capsaicinoids significantly increased fat oxidation and EE (+58.56 kcal/day) . Similarly, more recent meta-analyses have shown inconsistent relationships but have evaluated the whole food and not supplements 147,148. Early studies assessed the food and not capsaicinoid or capsinoid extracts but attributed putative effects to capsaicin. Individuals with certain health conditions or those taking medications should consult a healthcare provider before using any supplements. While natural supplements can be beneficial, they can also cause side effects and interact with medications. Look for supplements containing ingredients that have been scientifically validated. Some strains may help regulate appetite and reduce fat absorption, contributing to weight management. Consistent training, whether in the gym or on the track, is crucial to building muscle and losing weight. The natural, quality formula contains 53 grams of protein and 109 grams of carbs per serving, making it quite effective in building lean muscle and helping you gain weight. Building mass in that way—aka a dirty bulk—can be harmful to your goals because any gains you make will most likely come from fat instead of muscle. To build muscle, you're going to need a larger intake of macronutrients like protein, carbohydrates, and fats to ensure a clean bulk, rather than consuming excess calories from less-than-ideal sources to hit your numbers. Lastly, the TestoPrime formula contains no sugar, gluten, dairy, soy, or GMOs and features FDA-approved ingredients. Eating well and staying active are key to weight loss and a long, happy, healthy life! A 2023 study found moderate but significant weight loss with 10 grams of psyllium husk per day for 16 weeks, with an average weight loss of 5 pounds—no diet required. Studies show an average person using higher doses of a weekly semaglutide injection loses about 15 percent of their body weight—and that number goes as high as 22 percent when diet and exercise are added. Study participants given the generic version of the drug, tirzepatide, lost an average of 21 percent of their body weight over 72 weeks with no special diet or exercise and up to 26 percent with diet and exercise. Some weight-loss supplements have been found to have ingredients that aren't listed on the label, such as prescription medicines.