The following information includes only the average doses of this medicine. The dose of this medicine will be different for different patients. You will need to stop using opioids for at least 7 to 10 days before you can start taking naltrexone. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco. Other Interactions Blood tests may be needed to check for unwanted effects. Ask your healthcare professional how you should dispose of any medicine you do not use. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Take this medicine only as directed by your healthcare provider.The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.This will allow your healthcare provider to see if the medicine is working properly and to decide if you should continue to take it.Using this medicine with any of the following medicines is not recommended.You may report side effects to the FDA at FDA-1088.Your healthcare provider may need to do the naloxone challenge test or a urine test for opioids to make sure you are opioid-free.It can be prescribed by any healthcare provider who is licensed to prescribe medications, special training is not required. Missed Dose If a person relapses and uses the problem drug, naltrexone prevents the feeling of getting high.The pill form of naltrexone (ReVia, Depade) can be taken at 50 mg once per day.Instead, they should consult their health care provider or substance misuse treatment practitioner to adjust the dose or change the medication.A potential downside for patients, though, is that it can only be administered after opioid withdrawal takes place.No information is available on the relationship of age to the effects of naltrexone in geriatric patients.Using alcohol or tobacco with certain medicines may also cause interactions to occur.Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Using this medicine with any of the following medicines is not recommended. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding. Appropriate studies have not been performed on the relationship of age to the effects of naltrexone in the pediatric population. If you miss a dose of this medicine, take it as soon as possible. If your dose is different, do not change it unless your doctor tells you to do so. Your healthcare provider may need to do the naloxone challenge test or a urine test for opioids to make sure you are opioid-free. The presence of other medical problems may affect the use of this medicine. Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. The amount of medicine that you take depends on the strength of the medicine.The length of time this takes may depend on which opioid you took, the amount you took, and how long you took it.People using naltrexone should not use any other opioids or illicit drugs; drink alcohol; or take sedatives, tranquilizers, or other drugs.This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally.Never share this medicine with anyone else, especially someone who is using opioids.Naltrexone treatment is started after you are no longer taking opioids for a period of time.The injectable extended-release form of the drug (Vivitrol) is administered at 380 mg intramuscular once a month. If you notice any other effects, check with your healthcare professional. Other side effects not listed may also occur in some patients. These side effects may go away during treatment as your body adjusts to the medicine. Naltrexone's indications, mechanism of action, pharmacokinetics, administration methods, significant adverse effects, contraindications, monitoring, warnings, and toxicity are discussed.Patients on naltrexone may have reduced tolerance to opioids and may be unaware of their potential sensitivity to the same, or lower, doses of opioids that they used to take.Ask your healthcare professional how you should dispose of any medicine you do not use.Naltrexone can be prescribed by any health care provider who is licensed to prescribe medications.Naltrexone blocks the effect of opioids and prevents opioid intoxication and physiologic dependence on opioid users.Along with its needed effects, a medicine may cause some unwanted effects.Research has shown that naltrexone decreases reactivity to drug-conditioned cues and decreases craving.If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. This medicine is available only with your healthcare provider's prescription. It also may block the euphoric and rewarding feeling that may make you want to use alcohol. Naltrexone for Opioid Use Disorders Naltrexone also blocks the useful effects of opioids.It will not prevent you from becoming impaired while drinking alcohol or using opioids.Do not take naltrexone in order to drive or perform other activities while under the influence of alcohol.It is important that medical managed withdrawal (detoxification) from opioids be completed at least 7 to 10 days before extended-release injectable naltrexone is initiated or resumed.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.It’s considered a replacement medication, like methadone, because it is a partial agonist.To reduce the risk of precipitated withdrawal, patients are warned to abstain from illegal opioids and opioid medication for a minimum of 7-10 days before starting naltrexone.Extended-release injectable naltrexone is approved for treatment of people with opioid use disorder. It works by blocking the effects of opioids, especially the euphoric and rewarding feeling that makes you want to use them. Naltrexone is used to help patient with opioid use disorder who have stopped taking opioids to stay drug-free and maintain their recovery. Vivitrol, the brand name for naltrexone, is a narcotic blocker or what’s known as an opioid antagonist. Research has shown that naltrexone decreases reactivity to drug-conditioned cues and decreases craving. People taking naltrexone may experience side effects, but they should not stop taking the medication.Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur.If your dose is different, do not change it unless your doctor tells you to do so.Always use a non-opioid medicine to treat pain, diarrhea, or a cough.If you miss a dose of this medicine, take it as soon as possible.The dose of this medicine will be different for different patients.As with all medications used in medication-assisted treatment (MAT), naltrexone is to be prescribed as part of a comprehensive treatment plan that includes counseling and participation in social support programs.Tell all medical healthcare providers, dentists, and pharmacists you go to that you are taking naltrexone. If you have any questions about the proper medicine to use, check with your healthcare provider. Always use a non-opioid medicine to treat pain, diarrhea, or a cough. Remember that use of naltrexone is only part of your treatment. This medicine may cause some people to be agitated, irritable, or display other abnormal behaviors. Do not take more of it, do not take it more often, and do not take it for a longer time than your healthcare provider ordered.Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.The following information includes only the average doses of this medicine.Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.It is very important that your healthcare provider check your progress at regular visits.Naltrexone is an FDA-approved opioid antagonist used to treat alcohol use disorder and opioid dependence.Some side effects may occur that usually do not need medical attention.It will not produce any opioid-like effects or cause mental or physical dependence.Naltrexone causes withdrawal symptoms in people who are using opioids. Naltrexone can be prescribed by any health care provider who is licensed to prescribe medications. The injectable extended-release form of the drug (Vivitrol) is administered at 380 mg intramuscular once a month. The pill form of naltrexone (ReVia, Depade) can be taken at 50 mg once per day. Naltrexone's indications, mechanism of action, pharmacokinetics, administration methods, significant adverse effects, contraindications, monitoring, warnings, and toxicity are discussed. You may report side effects to the FDA at FDA-1088. It is recommended that you carry identification stating that you are taking naltrexone. Do not drive or do anything else that could be dangerous until you know how this medicine affects you. Naltrexone will not prevent you from becoming impaired when you drink alcohol. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The amount of medicine that you take depends on the strength of the medicine. Do not take more of it, do not take it more often, and do not take it for a longer time than your healthcare provider ordered. Take this medicine only as directed by your healthcare provider. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed. This will allow your healthcare provider to see if the medicine is working properly and to decide if you should continue to take it. It is very important that your healthcare provider check your progress at regular visits. Naltrexone treatment is started after you are no longer taking opioids for a period of time. People taking naltrexone may experience side effects, but they should not stop taking the medication. As with all medications used in medication-assisted treatment (MAT), naltrexone is to be prescribed as part of a comprehensive treatment plan that includes counseling and participation in social support programs. Naltrexone blocks the euphoric and sedative effects of drugs such as heroin, morphine, and codeine. If switching from methadone to naltrexone, the patient has to be completely withdrawn from the opioids. International Patients If a person relapses and uses the problem drug, naltrexone prevents the feeling of getting high. This medication is a mu-opioid receptor antagonist and also a weaker antagonist of the kappa and delta-opioid receptors. Naltrexone blocks the effect of opioids and prevents opioid intoxication and physiologic dependence on opioid users. Naltrexone is an FDA-approved opioid antagonist used to treat alcohol use disorder and opioid dependence. Call your doctor for medical advice about side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Along with its needed effects, a medicine may cause some unwanted effects. It may also cause some people to have suicidal thoughts and tendencies or to become more depressed.Naltrexone's indications, mechanism of action, pharmacokinetics, administration methods, significant adverse effects, contraindications, monitoring, warnings, and toxicity are discussed.If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.This medicine blocks the euphoric and rewarding feeling you get from opioid drugs, including heroin.It works by blocking the effects of opioids, especially the euphoric and rewarding feeling that makes you want to use them.Blood tests may be needed to check for unwanted effects.If you have any questions about the proper medicine to use, check with your healthcare provider.This medicine is available only with your healthcare provider's prescription. Tell all medical healthcare providers, dentists, and pharmacists you go to that you are taking naltrexone. This medicine may cause some people to become dizzy, drowsy, or less alert than they are normally. Do not take naltrexone in order to drive or perform other activities while under the influence of alcohol. Side Effects This medicine blocks the euphoric and rewarding feeling you get from opioid drugs, including heroin. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines. Your doctor may decide not to treat you with this medication or change some of the other medicines you take. Naltrexone will cause withdrawal symptoms in people who are no longer taking opioids for a period of time. A potential downside for patients, though, is that it can only be administered after opioid withdrawal takes place. Instead, they should consult their health care provider or substance misuse treatment practitioner to adjust the dose or change the medication. Drug Interactions Extended-release injectable naltrexone is approved for treatment of people with opioid use disorder. Naltrexone is a medication approved by the Food and Drug Administration (FDA) and used in medication-assisted treatment (MAT) to treat both opioid and alcohol use disorders. Naltrexone causes withdrawal symptoms in people who are using opioids. You may be more sensitive to the effects of opioids than you were before beginning naltrexone therapy. Do not try to overcome the effects of naltrexone by taking opioids. Medical Professionals The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive. There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. It’s considered a replacement medication, like methadone, because it is a partial agonist. Extended-release naltrexone should be part of a comprehensive management program that includes psychosocial support. It can be prescribed by any healthcare provider who is licensed to prescribe medications, special training is not required. Naltrexone binds and blocks opioid receptors and is reported to reduce opioid cravings. It works differently in the body than buprenorphine and methadone, which activate opioid receptors in the body that suppress cravings. Some side effects may occur that usually do not need medical attention. Although not all of these side effects may occur, if they do occur they may need medical attention. Never share this medicine with anyone else, especially someone who is using opioids. Naltrexone also blocks the useful effects of opioids. Other Interactions Patients on naltrexone may have reduced tolerance to opioids and may be unaware of their potential sensitivity to the same, or lower, doses of opioids that they used to take. People using naltrexone should not use any other opioids or illicit drugs; drink alcohol; or take sedatives, tranquilizers, or other drugs. To reduce the risk of precipitated withdrawal, patients are warned to abstain from illegal opioids and opioid medication for a minimum of 7-10 days before starting naltrexone. It is important that medical managed withdrawal (detoxification) from opioids be completed at least 7 to 10 days before extended-release injectable naltrexone is initiated or resumed. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Before you start taking this medicine, be sure to tell your healthcare provider if you think you are still having withdrawal symptoms. The length of time this takes may depend on which opioid you took, the amount you took, and how long you took it. It will not produce any opioid-like effects or cause mental or physical dependence. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. No information is available on the relationship of age to the effects of naltrexone in geriatric patients. It will not prevent you from becoming impaired while drinking alcohol or using opioids.