Vitamin D comes naturally if you spend a little time outdoors in the sun every day, but it’s a common nutritional deficiency now that we spend so much of our lives indoors. The study found that results were maximized when fresh green tea with higher concentrations of caffeine and catechins was consumed. You may even benefit from B12 shots or injections if you have a vitamin B12 deficiency or the shots are combined with other therapies like restricted calorie intake. That may leave you running to the supermarket or pharmacy for a bottle of vitamin B12, but pause for just a moment. But, the truth is that vitamin supplements can’t replace a healthy diet and lifestyle. A diet full of nutrient-dense foods gives you enough vitamins for weight loss support. Getting enough of these vitamins helps your body work well, keeping you at a healthy weight. Always make sure to consult with your doctor before ingesting a new supplement or pill. The health and safety of ACTIVE’s readers is of the utmost importance to us. They often contain ingredients that work to boost your metabolism, which may result in more calories burned. Why Trust Everyday Health As with all supplements, you should talk to your healthcare provider before taking it. Many people experience side effects from caffeine such as a rise in blood pressure and heart rate, sleep problems, anxiety or jitteriness or gastrointestinal problems. It can give you a jolt of energy, boost your metabolism and increase fat breakdown, Willis says. A 2020 systemic review of 32 studies found most adults don’t lose weight when taking a magnesium supplement. Of six studies on the micronutrient in the Obesity meta-analysis, three had a low risk of bias and only one of those linked it to weight loss ranging from 3 to 6 pounds. Transparent Labs' Magnesium Bisglycinate tablets provide 300 grams of reportedly highly bioavailable, non-laxative magnesium supplement intended to improve sleep, recovery, and energy levels. The above is just a sampling of available research on how protein can assist with weight loss. A 2020 clinical trial published in the Journal of Obesity & Metabolic Syndrome19 concluded that a high-protein diet “is an effective and safe tool for weight reduction that can prevent obesity and obesity-related diseases.” (By the way, that review looks at 23 separate studies that show how probiotics aid weight loss). We Asked 6 Dietitians to Share the Most Helpful Weight Loss Supplements for Women One thing that all of these weight loss supplements have in common is they are best used along with lifestyle modification, including a healthy diet and exercise. Instead of reaching for supplements, choose a healthy, balanced diet, rich in vitamins and minerals to ensure you are getting the most from your foods to help fuel you towards your weight loss goals without the risk of the unknown. Here’s a comprehensive breakdown of the top science-backed weight loss supplements for women, from vitamins that support metabolism to prescribed weight loss medications. Interest in natural weight loss solutions is set to surge in 2025, as more people seek effective and sustainable ways to reach their health goals. This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements. That said, GLP-1 medications for weight loss are not for everyone, and they can cause unpleasant, even serious, side effects, including gastrointestinal issues like nausea and diarrhea, and pancreatitis, an inflammation of the pancreas. Ask your prescriber about the safest and most effective medication for your body-weight goals. Many people consider Wegovy to be the strongest weight-loss pill. Make sure to talk to a healthcare professional who prescribes weight-loss medications about your overall treatment goals. Based on data reported in clinical studies, Wegovy is likely the most effective prescription weight-loss pill. Despite promising mechanistic data, evidence that these supplements are safe and effective is lacking, limiting their clinical usefulness.The Mayo Clinic Healthy Weight Pyramid is a tool to help you lose weight or maintain your weight.The study performed by Stanko et al. was a double-blind, placebo-controlled trial which evaluated body composition with a low energy diet and supplementation with pyruvate.From metabolism boosters to appetite suppressants, this guide covers the best options for weight loss supplements and medications.The Mayo Clinic Diet is meant to be positive, practical, sustainable and enjoyable, so you can enjoy a happier, healthier life over the long term.These essential nutrients play a crucial role in supporting cardiovascular health, cognitive function, and overall well-being.They also must make sure that their products are free of harmful substances and that they have correct labels.While food should be your first source for vitamins that help with weight loss, supplementation can fill nutritional gaps. However, the magnitude of weight loss attributed to caffeine alone typically does not exceed 0.5 kg after three months, highlighting its role as an adjunct rather than a primary driver. National Institutes of Health (NIH) and the World Health Organization (WHO) remains that supplements should complement-not replace-evidence‑based dietary and physical‑activity interventions. While some supplements show modest effects in controlled settings, the overall consensus from agencies such as the U.S. Supplements that are based on all-natural ingredients can be healthy, though we would recommend checking with your doctor before you start taking anything, especially anything with a high concentration of caffeine. Next up, we looked to the scientific research to find answers on the most effective natural weight loss supplements. Our natural weight loss supplements were informed by the best scientific research on plant-based and herbal compounds for losing weight. Other weight loss supplements act as appetite suppressants, making you less inclined to eat a lot of calories at your next meal. This can help people with a stubborn metabolism lose more weight than had they just tried diet and exercise alone. It also leverages caffeine, green coffee bean extract, and green tea extract for powerful metabolism-boosting effects, making it the best choice for men who are serious about weight loss. Additionally, it’s common to regain weight when you stop taking a diet pill.We put much less weight on lab animal studies.Moreover, Vitamin E is a potent antioxidant that helps to combat oxidative stress, a factor that can contribute to excess belly fat.Meal replacement shakes are an easy way to potentially reduce your calorie intake to promote weight loss, while still providing your body what it needs.Modern eating habits present unique challenges in obtaining enough vitamins that help with weight loss.Always prioritize safety by selecting high-quality products and consulting with a healthcare professional. Caffeine is a stimulant and a popular ingredient in many weight-loss supplements. People with low vitamin C levels are more resistant to fat loss when exercising. A meta-analysis of studies looking at the use of green tea or green tea extracts for weight loss found green tea preparations to exert a small weight-loss effect in overweight subjects. Obese people have lower vitamin D levels than non-obese people. But do any of these weight-loss supplements actually work? It’s not a matter of beefing up your levels of iodine, but filling in a deficiency if one exists. Your thyroid needs certain levels of iodine in order to do its job, so a deficiency in this area will lead to poor performance. If your thyroid is out of whack, you’ll have a tougher time slimming down because your metabolism will also be out of line, and you’ll retain more water. Some have argued that it would be cheaper and just as effective to use caffeine instead. It’s best to work with a professional with experience in vitamin B therapies to get the best and healthiest results. Take the Nutritionist Quiz and we’ll match you with a dedicated weight loss nutritionist. The remaining products were selected for purity, quality, and clean supplement design. We put much less weight on lab animal studies. When evaluating the scientific research, we placed the most weight on randomized experiments on humans, especially when positive findings had been replicated in multiple studies. It is highly advisable to speak with your healthcare provider before starting a weight loss supplement. While supplements may provide an extra boost, they should be viewed as just one tool in a comprehensive weight loss strategy. While supplements may aid in boosting metabolism, reducing appetite, or increasing fat burning, they are not a substitute for sustainable lifestyle changes. Health care providers should be aware of the weight loss products available to their patients and assist patients in determining the risks and benefits of supplement use for weight loss. The study performed by Stanko et al. was a double-blind, placebo-controlled trial which evaluated body composition with a low energy diet and supplementation with pyruvate. Onnit Total Human stands out from the typical multivitamins that cram nutrients into one or two pills. Supplements are rarely the answer to safe, sustained weight loss. Learn all you can about any weight-loss supplement you think about trying. Ephedra (ma-huang) is an herb once used for weight loss. For example, caffeine increases metabolic rate by stimulating the central nervous system. It has been shown to improve cardiovascular health by reducing markers of oxidative stress and inflammation, which are linked to heart disease. Emerging research suggests that vitamin D may have a protective effect against certain cancers and cardiovascular diseases. Furthermore, maintaining a balanced gut microbiota can improve mental health by influencing the gut-brain axis, potentially reducing symptoms of anxiety and depression. The Food and Drug Administration (FDA) does not regulate supplements like they do for prescription medications. Don’t you want to know exactly what is in that fancy, all-natural mixture that promises to annihilate 10lbs of body fat in one week? There is a lot of research that has been done on the use of different vitamins and minerals in that multivitamin you take but the research on these popular herbs and extracts being thrown into the mix is scarce.1 To give you a little more insight into supplements, let’s talk over the counter. Some ingredients in the supplements could have a negative reaction to a medication you are taking or effect a condition you have. This is the case of a 35-year-old woman on stable treatment with escitalopram (an SSRI) for one year, who developed tremors, flushing, and diaphoresis after using a GC extract (60% HCA) supplement for weight loss during the last 2–3 months. In 20 human studies, 12 reported significant reductions in body weight, and the rest were considered ineffective. Most GC supplements contain 20–60% HCA , which has been shown to be a competitive inhibitor of adenosine triphosphate (ATP)-citrate lyase, thereby reducing the availability of ATP acetyl-Coenzyme A for the formation of fatty acids and cholesterol, attenuating fat accumulation . Vitamin A is a standout among vitamins that help with weight loss thanks to its regulatory effects on fat cell development and hormone balance.It’s similar in design to a carb blocker, except that it blocks fat absorption instead.Resveratrol has been shown to be a potent inhibitor of the CYP3A4/5 enzyme, strongly inhibiting the metabolism of testosterone and midazolam (substrates of this enzyme).It helps turn carbs and fats into energy for your day.The mean difference in weight loss ranged from 0.2 kg to 3.5 kg compared with a placebo.Whether you’re looking to curb your appetite, improve gut health, or enhance your workout performance, there’s something here for everyone.Studies show that adults who get 7–9 hours of sleep per night maintain healthier metabolic rates and are less likely to experience micronutrient deficiencies. However, in vitro and rodent studies showed the inhibition of a number of CYP enzymes in contact with EGCG. Green tea is the infusion of the unfermented (unoxidized) leaves of the Camellia sinensis plant, which has been used for medicinal purposes throughout history and has been extensively studied in recent decades for its potential health benefits . Fortunately, most of these interactions, if known, are predictable and the drug dose can be adjusted or the supplement discontinued if necessary . This process included reviewing the title and abstract for screening, then reading other publications, and finally reading the full text of the selected studies. Rounding out the list of vitamins that help with weight loss, vitamin K supports glucose metabolism and cardiovascular health. Mindful eating and regular meal planning help ensure consistent intake of vitamins that help with weight loss, supporting metabolism and overall health. The ACTIVE Reviews Team decided on our list of the best weight loss supplements for men by researching products from brands we trust with transparent ingredients and formulas, certifications, value for cost, and overall positive word-of-mouth from reviewers. To ensure your well-being when consuming weight loss supplements, the ACTIVE.com editorial team prioritizes products that are independently tested by a third party. Sponsorships and affiliate commissions help support our research so we can help you find the best products. This review will examine the scientific evidence of key ingredients found in supplements and functional foods, along with any safety issues or concerns. Combined with personalized behavioral health coaching and medically guided care, they can make a big difference in your ability to lose weight and keep it off. These delicious, creamy shakes contain vitamins at up to 450% of the recommended daily allowance (RDA) and all 72 minerals. Selection of studies Ceylon cinnamon contains far lower levels of coumarin, reducing liver‑toxicity concerns. How long should I take a cinnamon supplement to see any effect? People with liver disease, bleeding disorders, or those on anticoagulant medication should consult a physician before initiating any cinnamon supplement regimen. Age‑related declines in renal function can affect coumarin clearance; thus, low‑coumarin cinnamon preparations or alternative strategies (e.g., Mediterranean diet) are advisable. Overall, the mechanistic rationale is biologically plausible, but translation into meaningful weight reduction remains uncertain. You'll first want to ensure you’re following an appropriate diet and exercise program.If you’re wanting to lose weight, try weight loss supplements that’d work for anyone.This process included reviewing the title and abstract for screening, then reading other publications, and finally reading the full text of the selected studies.Isolated supplement use rarely yields clinically meaningful loss.2.Sticking to clean foods and a healthy lifestyle should be at the core of your weight loss, but a weight loss supplement can give you an added boost.In vitro studies have shown that quercetin is a potent inhibitor of CYP1A2 and CYP3A4, an effect confirmed in rodents .The kind of whey protein you use will vary depending on your fitness goals, and what kind of training you’re doing. OmegaHealth is a highly purified, high-dose omega-3 supplement that supports heart and metabolic health. When your body lacks these essential nutrients, it can slow your metabolism, increase fatigue, weaken your immune system, and even make it harder to lose fat. Even if you eat regularly, your body might not absorb nutrients as effectively due to inflammation, poor gut health, or other metabolic changes linked to excess weight. However, even a healthy diet needs a boost, especially when certain nutrients are missing. At Hopkins MD, we know that a successful and sustainable weight loss journey takes a personalized, whole-body approach. Copper Water: Basics, Benefits, and Downsides These effects have been studied in cell culture and in vitro, but human studies are very limited. Another comparative study between chitosan and orlistat (a pancreatic lipase inhibitor) concluded that chitosan did not inhibit the absorption of dietary fat . Several meta-analyses have attempted to test the efficacy of chitosan in weight loss with conflicting results. Given that the efficacy of GC extract has not been fully demonstrated and that the occurrence of serious adverse effects appears to be attributable to HCA, the risk–benefit balance is not in favor of taking this supplement. The patient was admitted to hospital with symptoms of serotonin syndrome, and treatment with SSRIs and GC supplements was discontinued . In the meantime, and especially because it’s Medicare open enrollment, Gallagher suggests looking for a health plan that covers the medications you are currently taking. Medicare currently covers GLP-1s for diabetes and other approved ailments — such as obesity in conjunction with heart disease — but is legally barred from covering the medication for weight loss alone. A recent report from the health policy nonprofit KFF found that across age groups, GLP-1 use is highest among people between the ages of 50 and 64. Practically, what this means is that there’s no way of knowing what’s actually in a supplement unless it’s independently tested by a third-party agency—or until a consumer suffers from health complications and the FDA investigates. But the FDA can’t actually enforce anything until after supplements are made available to consumers and reports of adverse effects are made. Here are some common side effects or risks with some of the supplements we’ve recommended. The tolerable upper intake level represents the max amount of a substance that can be consumed before adverse effects occur. Iodine42 is a mineral needed by the body for several purposes, but primarily the synthesis of thyroid hormones T3 (triiodothyronine) and T4 (thyroxine). It does this by reducing inflammation on the cellular level, modulating mitochondria’s energy and reducing stress on the endoplasmic reticulum of cellular level. Omega-3 fatty acids have been shown to counteract insulin resistance and increase insulin sensitivity, as noted in a 2018 review36. In severe cases, too much caffeine can cause abnormally high heart rate and seizures. Raspberry ketones have gained popularity as a natural weight loss supplement, thanks to their potential to enhance fat metabolism. Chromium Picolinate is a popular supplement that many people turn to for weight loss support. While you may have heard of various weight loss supplements, forskolin stands out as a natural option derived from the roots of the Coleus forskohlii plant. Green tea extract is one of the most popular supplements for weight loss, and it’s easy to see why. Quercetin may also be able to reduce obesity in rodents on a high-fat diet by modifying the gut microbiota; however, it appears that most of the anti-obesity effects of quercetin are due to its antioxidant and anti-inflammatory properties 37,38,39. Although chitosan may have shown promising results, the reality is that studies to date have not been able to demonstrate its efficacy in the management of obesity, and the adverse effects, however few and however mild (bloating, constipation, nausea, etc.), mean that, for the time being, chitosan cannot be recommended for weight reduction 7,15,31. Chitosan may scavenge fat-soluble substances, thereby interfering with the absorption of vitamins A, D, E, and K (fat-soluble) , which in combination with vitamin K antagonists such as warfarin and acenocoumarol may increase the anticoagulant effect, thereby increasing the risk of bleeding. Early studies showed significant weight loss, but more recent studies do not show the same results; when only the highest quality clinical trials are analyzed, the average amount of weight lost is only 0.6 kg. He has a background in investigative and science journalism and has worked on documentary films about war and trauma, health, sanitation, and the changing climate around the world. Orlando de Guzman is a writer and editor with expertise in health and environmental news. She's currently a contributor for Everyday Health and Yahoo Life, and her work has also appeared in Forbes Vetted, Healthline, Greatist, mindbodygreen, and Bicycling magazine, among other outlets. (8) XWERKS Grow, a super lean protein powder, can be an asset to a well-balanced high-protein diet.”Supplements are actually regulated just like food products.Studies have shown only a moderate weight loss effect, however.15If you are vegetarian or vegan, choosing over the counter or medications for weight loss can be difficult as gelatin is a common ingredient in pill capsules.At a minimum, consult with a registered dietitian before taking it.Close to 50% of participants lost at least 10% of their body weight.Consumers report juggling busy schedules, irregular meal timing, and sedentary office work while hoping to maintain a healthy body weight. Magnesium: The Relaxation Mineral for Weight Loss We will interpret random‐effects meta‐analyses with due consideration for the whole distribution of effects and will present a prediction interval (Borenstein 2017a; Borenstein 2017b; Higgins 2009). Several explanations may account for funnel plot asymmetry, including true heterogeneity of effect with respect to study size, poor methodological design (and hence bias of small studies) and selective non‐reporting (Kirkham 2010). When we identify heterogeneity, we will attempt to determine the possible reasons for this by examining individual characteristics of the studies and subgroups. In view of the low power of this test, we will also consider the I² statistic — which quantifies inconsistency across studies — to assess the impact of heterogeneity on the meta‐analysis (Higgins 2002; Higgins 2003). We will investigate the impact of imputation on meta‐analyses by performing sensitivity analyses, and we will report for every outcome which studies had imputed SDs. Prescription drugs are medicines that a health care provider prescribes for you. If you answered yes to these questions, a prescription weight-loss drug may be a choice for you. It has taught Oakley that “optimizing body and mind” flourishes precisely at the wellspring of community. If you’ve noticed persistent, unexplained muscle discomfort, it might be time to check your vitamin D levels. You can get vitamin D from egg yolks, fatty fish, and fortified foods like milk and orange juice. Despite its name, vitamin D isn’t a vitamin — it’s a hormone produced in your kidneys. Always consult your physician before beginning any supplement, nutrition or exercise program and/or if you are taking any over-the-counter or prescription medications. Always talk to a healthcare professional before taking supplements. They are key for a healthy weight and overall health. Always talk to a doctor before taking any supplements, as they can interact with medicines or cause side effects. It keeps your body’s metabolism and weight control working well. For ideas, take a look at our guide to the best fiber supplements. Glucomannan is in many popular weight loss pills, including Leanbean and Trimtone. The former is what you want if you’re trying to lose weight, says registered dietitian Destini Moody, while the latter mostly serves to add bulk to stool and move things along in the gastrointestinal tract. As a potent antioxidant, quercetin has been shown to support cardiovascular health, promote healthy immune function, and even enhance physical performance and recovery.One of the key advantages of quercetin supplementation is its ability to support a healthy inflammatory response. This is where vitamin D supplementation can be a game-changer, helping to ensure that your body has the necessary levels of this vital nutrient.When selecting a vitamin D supplement, look for formulations that provide vitamin D3 (cholecalciferol), as it is the most bioavailable and effective form of the nutrient. Probiotic supplements containing strains like Lactobacillus and Bifidobacterium have been shown to promote a balanced gut flora, enhance immune defenses, and even aid in weight management efforts.Complementing probiotic supplementation, fiber-rich supplements can also contribute to optimal gut health. Maintaining a healthy gut is not only crucial for proper digestion and nutrient absorption but also has far-reaching implications for our immune function, mental health, and even weight management.Supplementing with probiotics, which are live beneficial bacteria, can help to replenish and support the gut microbiome. This is where a high-quality multivitamin supplement can step in to fill the gaps and ensure that your body is receiving the essential nourishment it needs.Multivitamin formulas are designed to provide a comprehensive blend of vitamins and minerals, often including the B-complex, vitamin C, vitamin D, and essential minerals like magnesium and zinc. Alli, a lower dose version of the prescription Orlistat, is the only FDA approved weight loss supplement you can buy over the counter at your local drug store. The Dietary Supplement Health and Education Act of 1994 placed herbal remedies in the same category as dietary supplements. It is essential, whether taking a prescription or an over-the-counter weight loss supplement, to talk to your doctor and make sure you have all the facts. Second, you will most likely have rebound weight gain once you stop taking those supplements. Best High-Protein Meal Delivery ( : 8 Options That Can Help You Build Muscle And Stay Full Breast health Bone and joint health MetAssist is one of our favorite tools for helping patients lose weight faster and more effectively. OmegaHealth fills that gap and gives your cardiovascular and metabolic systems the support they need. People who have hunger cravings when dieting. If you’re looking to lose weight quickly, PhenQ’s formulation is the way to go. Women who struggle to keep their fat oxidation high and their hunger cravings under control should opt for LeanBean. Vitamin D stands out among vitamins that help with weight loss due to its direct impact on fat storage and insulin sensitivity. Unlocking the power of vitamins that help with weight loss can be a game changer for your 2025 health journey. Addressing these factors can help ensure the body receives the full benefit of vitamins that help with weight loss. When the body lacks certain vitamins, metabolism can slow, making it harder to lose weight. Because vitamin D helps your body absorb calcium, it’s essential for bone health. Pregnant or Breastfeeding Women – Most weight‑loss supplements lack safety data for this group; professional guidance is essential before any intake. Interest in these supplements has surged alongside the personalized nutrition movement and the 2026 wellness trend of "data‑driven health," where consumers use wearables and nutrition apps to tailor intake. Caffeine, green tea catechins, and fiber (glucomannan, psyllium) have multiple high‑quality trials supporting modest effects on energy expenditure or satiety. Importantly, many supplements display a dose‑response curve that plateaus or reverses at higher intakes due to tolerance or side‑effects. It helps with fat metabolism and can aid in weight management. Human studies on vitamin B12 and metabolism are limited but interesting. Vitamin D might also help with weight loss by controlling fat cells. They help with metabolism, energy, and hormone balance, all important for weight management. Weight loss supplements that include proven, natural ingredients, and that are paired with diet and exercise, can certainly be effective. Certain vitamins can help bolster your body's fat-burning abilities. Many of the products on our list contain ingredients to help support thermogenesis, or the heating up of the body to produce energy and burn excess calories. Each scoop comes loaded with holistic ingredients like caffeine and organic apple cider vinegar, designed to stimulate energy, improve metabolism, and burn fat.(4) It contains 100% natural—and familiar—ingredients to help suppress appetite, increase energy levels, and boost your metabolism, like cayenne pepper seeds, caffeine, and glucomannan. Recent evidence suggests that adequate vitamin E intake is linked to improved insulin sensitivity and cardiovascular function. If you are looking to boost your intake, consider adding a daily fruit salad, fresh vegetable snacks, or a vitamin C-rich smoothie to your routine. Supplementation is often necessary for those on plant-based diets or with absorption issues. If you notice persistent tiredness or trouble losing weight, ask your doctor about testing for B12. A nutrient-dense diet rich in fiber-rich greens, vegetables, sprouts, herbs, spices, fruit, nuts, and seeds should be your number one way to increase fiber and support weight loss. It can support regular bowel movements and prevent constipation, which can also support you in maintaining a healthy weight (35, 36). Gut microbiome imbalances due to a poor diet, unhealthy lifestyle choices, chronic stress, medication use, and environmental toxins can increase chronic inflammation, gut inflammation, digestion problems, and weight gain. Probiotics are beneficial bacteria that support a healthy gut microbiome, which plays a critical role in digestion, metabolism, and overall health. According to a 2020 study published in Nutrition Hospitalaria, omega-3 fatty acids may help weight loss in overweight individuals on a weight-loss diet (25). However, other studies found no benefit, so more research is needed. According to the Obesity review, one well-designed study showed trial participants taking the supplement lost on average about six pounds. Number two, change your diet.” Focus on food-first strategies and consult a healthcare provider before adding high-dose supplements.Tools and resources on habit-building for weight loss can help you stay consistent.Because of this, there’s not really a supplement that addresses weight loss and menopause at the same time.Furthermore, carnitine may enhance recovery after exercise by reducing muscle soreness and fatigue.They have become popular through telehealth companies, which prescribe and sell them at much lower prices than the brand versions.Older adults who are having trouble losing weight.While many healthy dietary supplements for weight loss are derived from foods and considered low‑risk, safety considerations remain crucial.It’s unclear whether this will result in more states covering these products. However, the supplement does not seem to affect blood sugar levels in people without diabetes, according to an Examine.com research analysis. Other studies have linked low vitamin B12 levels to obesity, diabetes and high cholesterol in animals. One study found that vitamin B12 could play a role in fat metabolism. “Anytime you’re trying to lose weight, vitamins are important,” he explains. A multivitamin could be helpful – and certainly won’t hurt – if you have changed your diet to try to lose weight, Huntington says. Magnesium does more than just help with metabolism. Research shows magnesium helps with metabolism. It helps with relaxation and sleep, important for managing weight. To help with weight management, eat these zinc-rich foods every day. Many times it’s not about running a surplus of a particular vitamin, but rather making sure you don’t have a deficiency that’s holding you back. Our team is comprised of unbiased licensed nutritionists, dieticians and health professionals. MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. Resveratrol has also demonstrated in voluntary subjects that it can inhibit CYP1A2, modifying caffeine concentration, and CYP2D6, affecting dextromethorphan levels. Similarly, an increase in the bioavailability (Cmax and AUC) of diclofenac and chlorzoxazone was confirmed, indicating the inhibition of CYP2C9 and CYP2E1, respectively, in healthy patients pretreated with resveratrol. Current coverage through private insurance plans for these medications, when prescribed for weight loss, can be spotty, which is why people with insurance often pay out-of-pocket for the drugs or have high copays. Federal officials recently announced plans to make these medications more accessible and affordable, including to people who have Medicare, which currently does not cover medications strictly for weight loss. If we identify a deficiency, we develop a personalized treatment plan, which may include over-the-counter or prescription supplements to bring your levels back to normal. Vitamin D supports hair follicle health, so inadequate levels may reduce new hair growth. Vitamin D helps your cells produce energy, so when your levels are low, fatigue can creep in and sap you. Glucomannan – This is a dietary fiber that is showing some promising results, including being able to help you lose weight simply by taking it before a meal. Start doing cardiovascular exercises and weight training if you aren’t already, as it helps with the effectiveness of the fucoxanthin. This is a supplement you’d want to check in with your doctor on first to make sure it’s right for you. Silica is sold separately as a supplement, but the reported benefits of a daily intake of diatomaceous earth include healthier hair, teeth, and gums, lower cholesterol, and lower blood pressure. Studies have found that this compound can enhance fat oxidation and improve metabolic rate. Green tea extract is renowned for its fat-burning properties, primarily due to the presence of catechins such as epigallocatechin gallate (EGCG). Whether you’re looking to curb your appetite, improve gut health, or enhance your workout performance, there’s something here for everyone. Our top pick for gut health support, Gainful Fiber, offers a simple ingredient list that can help keep you regular.Your thyroid needs certain levels of iodine in order to do its job, so a deficiency in this area will lead to poor performance.About one-third of adults in the United States attempting to lose weight have utilized dietary supplements.Using laxatives for weight loss is also dangerous and not advisable as they can cause serious electrolyte imbalances leading to kidney and heart problems.Since Alli rids your body of the fat you ate, you can become deficient in some of those important fat-soluble vitamins.We encourage consumers to be skeptical of any product that promises quick fat loss or an increased metabolic rate.“When it comes to weight loss, I like to prioritize adding foods that support weight management rather than restriction,” says Bourgeois. The benefits of supplementing omega-3 are wide and varying, with some of them proven, and others only claimed. Omega-3 – This fatty acid is the most widely known and get the most attention than the rest. In addition to this it’s showing signs of being able to help treat chronic diseases due to its ability to help strengthen the immune system. However, there have been high‐profile safety concerns about herbal weight loss products worldwide (Corns 2002; MHRA 2016; Nortier 2000). One of the possible reasons consumers choose herbal medicines for weight loss is that such products are considered (by consumers) to be natural and safe. However, a smaller weight loss may also show beneficial effects for some outcome measurements (Ross 2016; Williamson 2015). Social and environmental influences, such as activity patterns (e.g. sedentary lifestyle), health‐related education and socioeconomic status are important in determining whether individuals develop excessive body weight (Swinburn 2004; Weinsier 1999; WHO 2000). Natural weight loss supplements can be a helpful addition to your weight management plan if chosen wisely and used responsibly. A balanced diet can enhance the effectiveness of supplements and support overall health. When choosing a natural weight loss supplement, it’s important to focus on those with scientific evidence supporting their efficacy. They can help you determine the appropriate supplements, dosages, and timing to ensure that you are getting the maximum benefits while minimizing any potential risks or interactions.Additionally, it's crucial to maintain a balanced and nutrient-dense diet, as supplements should be used to complement, not replace, a healthy and well-rounded eating pattern. Morning muffins are my absolute favorite especially with this added protein. I really like baking with the vanilla pudding protein. I like to mix it with the lemon protein or any of the clear proteins, but it also tastes great on its own! However, if you’re not used to eating this much fiber, you should gradually increase your fiber intake to prevent unpleasant side effects like bloating, gas, and constipation. It’s also more expensive than comparable creatine products, at about 50 cents per serving, as opposed to the more typical 30 to 40 cents. This creatine is also NSF Certified for Sport, so athletes can rest assured that it’s free of banned substances. Patients considering these supplements should talk to their healthcare providers. Weight-loss dietary supplements are widely used and available worldwide. Healthcare providers should inquire about weight-loss supplements to facilitate open discussion. The mean difference in weight loss ranged from 0.2 kg to 3.5 kg compared with a placebo. The data for human weight loss have been mixed, generally showing a modest effect. A meta-analysis published in 2019 showed that most trials reported non-significant or no weight loss from beta-glucans administered at a dose of 3 to 10 grams per day for 4 to 12 weeks. Despite promising mechanistic data, evidence that these supplements are safe and effective is lacking, limiting their clinical usefulness.