Moreover, COQ10 has been proven to have positive effects on cardiovascular diseases as well as improving oxidative stress in patients with type 2 diabetes. COQ10 also regulates NO breakdown, meaning that it helps NO last longer in the body. Like some of the other vasodilators mentioned, the body naturally produces COQ10, but it’s not always enough to keep up with our cells’ needs. If you’re looking for a vasodilation supplement that will not only work for vasodilation but also treat other causes of your ED, ginseng is a strong choice. Others seek to bypass the legitimate healthcare system due to either embarrassment of the underlying condition or desire for cheaper alternatives. Consumers of illicit PDE-5i often do not realize they are using counterfeit products and placing themselves at an unnecessary health risk. King’s Health Partners Mind & Body is committed to joining up mental and physical healthcare, training and research to improve health outcomes for our patients and service users. Exploring male sexual health showed me how our bodies are connected. Then, I found studies on sexual wellness vitamins and their role in natural tissue health. I'm not a doctor, but my story shows how vitamins for male enhancement can complement a healthy lifestyle. These side effects may go away during treatment as your body adjusts to the medicine. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection. Vitamin C is one of my favorite vasodilation supplements because it has so many powerful effects on the body. Nitric oxide helps to dilate and relax the blood vessels throughout the body, especially in and around the penis. In this way, a healthy vasodilation system is advantageous for overall sexual health. And of course, vasodilation opens up the vessels in the penis, so your mini-me can take in blood for an erection. A 2020 study in Journal of Sexual Medicine found that low D levels can cause erectile problems. Natural male growth supplements rich in vitamin C and biotin boost collagen production. Vitamins for better blood flow, such as those with vitamin E, relax blood vessels and reduce plaque. When blood flow improves, tissues swell and firmness increases. Strong erections depend on blood rushing into the penis. To establish the likely efficacy of each EI, we considered only those having at least one RCT demonstrating a positive, negative or no effect on the erectile function. The selected articles allowed us to clearly identify effective ingredients (EIs), namely, the substances proposed as having a clinically demonstrated efficacy on the improvement of erectile function. Taking into consideration only RCTs available in the literature regarding the single active ingredients that were shown to be useful in the treatment of ED, we critically evaluated the efficacy and safety of the DS formulations marketed in Italy as support for the treatment of erectile disorders. The beneficial effects have been scientifically evaluated and confirmed in meta-analyses of randomized clinical trials.6 For example, in a double-blind, placebo-controlled study, 45 men with moderate to severe erectile dysfunction had found improvement in their scores on erectile performance and sexual satisfaction after treated with three times daily doses of 900 mg Korean red ginseng for 8 wk.7 A similar study on 60 men with erectile dysfunction also reported marked improvement in erectile function including rigidity, penetration, and maintenance of erection after taking Korean red ginseng (1000 mg) three times daily for 12 wk.8 These B vitamins don’t work in isolation—they support each other in maintaining energy levels, nerve function, and healthy blood flow, creating a foundation for better sexual health. While vitamins cannot directly increase penis size, several nutrients play a vital role in supporting sexual health, erectile function, and hormone balance. Numerous sexual health problems, including erectile dysfunction,have been related to vitamin D insufficiency. Patients were then allowed to increase the dose at home (titration) under more favorable circumstances. As the neurotransmitter inducing penile erection, NO release was shown to be enhanced by GS in rabbit corpus cavernosum in vitro. The word Panax, in fact, means “all-healing” in Greek and is thus a reference to the roots supposed revitalizing properties for the whole human-body. For many years, Panax ginseng belonging to family Aralaceae has enjoyed a reputation as one of the finest aphrodisiacs in the world. An improvement in sexual desire was observed with Maca since 8 weeks of treatment. In conclusion, treatment with Maca does not affect serum reproductive hormone levels. The comparative evaluation between control and experimental groups revealed that consumption of DPP suspensions improved the sperm count, motility, morphology, and DNA quality with a concomitant increase in the weights of testis and epididymis. Spinach is high in nitric oxide and therefore, like other hard erection foods, helps arteries expand and fill up with blood. Watermelon’s citrulline content makes it similar to other foods for penis health, such as cucumber, bitter melons, and gourds. Nitric oxide regulates the flow of blood and the tone of smooth muscle, including that which is in the penis. Food can help improve erections because the processes involved in the swelling of the penis are both psychological and physical. Expression of progesterone receptor (PR) was observed on human sperms, and a strong correlation between PR expression and sperm function has been demonstrated.71 Intriguingly, unlike estrogens, progesterone promotes the capacitated sperm to undergo acrosomal reaction.72,73 In concordance, a handful of in vitro studies have demonstrated an inhibitory action of progesterone on estrogens and vice versa. At 70 years old, there’s nothing this legend hasn’t achieved in the body-building world. At number 4 on this best testosterone booster list, we have TestoFuel. I think it deserves a place on this list of the best testosterone boosters. Discover a healthier lifestyle with exclusive discounts and valuable wellness insights. If you’re asking “does shockwave therapy increase size? Yes, you can masturbate after peeing.For most people, masturbating after urination is medically safe and does not cause harm, infection, or long-term health issues. In a Korean double-blind placebo study3, 900mg’s of ginseng is taken 3 times per day for 8-weeks was able to significantly improve erectile quality of subjects with clinically diagnosed erectile dysfunction. While the evidence on ginseng’s ability to increase testosterone levels is mixed (raising the hormone on infertile men1, but not on men with no infertility2), the research behind its erection promoting effects is stronger than a steel pipe. While I can guarantee you that ginseng is nowhere near as potent as synthetic Viagra is, the benefit is that it’s all natural, costs just a fraction of the price, and actually works unlike many other natural erectile dysfunction supplements out there. Like so many of the modern-day pharmaceutical erectile dysfunction supplements, they’re just a mean to mask the real problem with a somewhat of a “robotic erection”. Sexual health has an important role in a man’s health and maintaining a healthy sexual function is essential for quality of life. A healthy diet and lifestyle are key for sexual health. Yes, some vitamins can have side effects, like zinc causing stomach issues. Some evidence suggests that many men with ED are also deficient in vitamin D. The science behind vitamin deficiencies and ED skews both ways. The Massachusetts Male Aging Study linked a healthier lifestyle (including a healthy diet) to a reduced risk for ED as well as diseases that can contribute to ED. Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats. Doctors in Karachi For others, these approaches work wonderfully alongside medical treatments, often allowing us to prescribe lower medication doses—which means fewer side effects for you. Think of vitamins as foundation builders rather than magic pills. By addressing the root causes rather than just treating symptoms, we help men achieve sustainable improvements in both sexual and overall health. This is because the small blood vessels in the penis are affected by atherosclerosis before larger vessels in the heart. Some men experience digestive discomfort, lower blood pressure, or increased herpes outbreaks (if you’re already prone to them) when taking L-arginine. As we get older, our testosterone levels plummet, making us feel tired, making it harder to gain muscle or burn fat, and sending our sex drive down the toilet. For the past few years, I’ve been testing out some of the best testosterone booster supplements on the market. Before investing in all the supplements listed in this article, remember that everyone’s health needs are unique. This article reviews the best multivitamin, vitamin D vitamin, zinc vitamin, and supplements for stress management, muscle gain, muscle recovery, and more. Furthermore, 39 out of the diabetic patients had antidyslipidemic treatment (27 subjects treated with statins and 12 treated with omega-3 fatty acids), and 37 diabetics had antihypertensive therapy (23 subjects treated with angiotensin-converting enzyme inhibitors and 14 treated with angiotensin receptor blockers). In fact, vitamin D may have a role also in type 1 and type 2 diabetes mellitus, Addison's disease, Hashimoto's thyroiditis, Graves' disease, and polycystic ovary syndrome 2–4. However, animal and human studies also suggest an involvement of vitamin D in the pathogenesis of several endocrine diseases 2–4. Vitamin D is mainly involved in the regulation of calcium/phosphorus homeostasis and bone health. Sildenafil, one of the phosphodiesterase inhibitors used as first line treatment in ED, induces a significant acute decrease in levels of pro-inflammatory markers/mediators . An extra mechanism of VD on erectile function seems to function via binding to T receptors. Canguven et al supported earlier research where serum total-T effectively increased after VD treatment 49,50. The results were significant and the researchers observed that overweight men with VDD had a clinically meaningful increase in serum T levels after VD supplementation for 1 year . This might partly explain why sexual health issues are so prevalent.The penis is made up of erectile tissue, blood vessels, and nerves, all of which contribute to its function and responsiveness.In conclusion, to be effective, a DS should be well-designed to act both acutely on the production of nitric oxide (locally in the penis) and chronically by normalizing the hormonal framework.Under the light of recent scientific researches, unsurprisingly, there exists a higher prevalence of ED among VD deficient patients compared to those with optimal levels .Tuberous roots of Chlorophytum borivilianum (CB) (commonly known as safed musli) (family Liliaceae) possess immunomodulatory and adaptogenic properties and are used to cure impotency, sterility, and enhance male potency.Determining and describing sexual performance is never simple, and it is subjective since everyone is different.It serves as the primary building block for nitric oxide—the molecule that relaxes blood vessels and makes erections possible. Icariin can boost mood and increase NO vasodilation, putting you on the fast track to an ED-free life. This is important because blood vessels tend to pop with age—and with exercise, which you should be doing if you want to keep your ED at bay. Icariin has been proven to be as beneficial as Viagra, but icariin actually has fewer side effects and more potent long-term influences. Vitamin C has a cocktail of properties of natural vasodilators and erection nourishment. This combo also lead to a drop in blood pressure of systolic 27mmHg and diastolic 15mmHg—that’s better than most blood pressure medications! It contains a tricyclic triterpene alcohol which increases the concentration of several anterior pituitary hormones and serum testosterone. Various substances of animal and plant origin have been used in folk medicines of different cultures to energize, vitalize and improve sexual function, and physical performance in men, out of these very few have been identified pharmacologically. Enhanced sexual behavior may provide increased relationship satisfaction and self-esteem in humans. An aphrodisiac is defined as any food or drug that arouses the sexual instinct, induces veneral desire and increases pleasure and performance. It might be difficult to talk about problems affecting your penis with your healthcare professional. And then, as far as examples of muscle-building ones, I don't really know any good supplements that kind of increase muscle. And then there's the other category of supplements that maybe can affect hormone levels. I mean, a lot of guys take one just because "Why not? Better safe than sorry. In case I'm missing some nutrients, my multivitamin will cover it." What's your take on multivitamins? A variety of botanicals are known to have a potential effect on the sexual functions, supporting older claims and offering newer hopes. Conclusion on Erectile Dysfunction Foods So, if you’re looking to improve your health in that area with Sexual performance is one of the many bodily functions L-Arginine is involved in. Determining and describing sexual performance is never simple, and it is subjective since everyone is different. Which Blood Pressure Medications Do Not Cause Erectile Dysfunction? These side effects are usually mild but should be considered before starting any new supplement regimen. L-arginine can sometimes lead to digestive discomfort or low blood pressure. Users should start with the lower end of the dosage range and adjust based on their response and advice from a healthcare provider. Horny Goat Weed supplements are available in capsule or tablet form. It is important to follow the dosage instructions provided on the product label or consult with a healthcare provider to determine the best dosage for your individual needs. Nitrate-dense leafy greens are one of the best foods for erectile health that you can consume on a daily basis… not to mention is it a seriously cheap option as well!. This in result relaxes arteries and allows the blood to circulate better, making leafy greens an ideal food for harder erections. Garlic consumption has also been shown in humans to be more potent at reducing blood pressure than most pharmaceutical solutions, needless to say, that this is beneficial for erectile quality, as high blood pressure is one of the leading causes of ED. Another benefit seen in studies with garlic is a reduction in inflammation, lowered blood pressure, and increased nitric oxide output. Sure they work in most cases, but it’s always good to remember that they deliver a chemical erection which your body still cannot naturally produce. CNY FERTILITY PHILADELPHIA: In this article, we explore various vitamins and foods that you should know about if you're interested in supporting a healthy and thriving penis. Incorporating a variety of vitamins and foods into your diet can potentially contribute to improved blood circulation, tissue health, and hormonal balance. Losing weight, reducing stress and a healthy lifestyle have all been shown to increase testosterone levels in men, Dr. Simone says. High Blood Pressure & ED: The Connection and What to Do Could vitamins like zinc or vitamin D really help with growth? I'll share which vitamins worked for me, how I took them, and why sticking to a routine is important. You may report side effects to the FDA at FDA-1088. Thousands of African medicinal plants (belonging to several genera and families, andwith diverse chemical constituents) have been reported to possess aphrodisiac andsexual stimulant properties (Koloko, pers commun). In Africa, from ancient times, plants have served as a dependable and ever-readysource of medicines for the treatment of a plethora of chronic and acute diseases ofmankind. The common side effects of the three PDE-5 inhibitorsinclude headache and dyspepsia, back pain, myalgia and non-arteritic anteriorischaemic optic neuropathy. Recent clinical studies have shown that the three PDE-5 inhibitors areeffective and relatively safe, and that they do not increase cardiovascular risk inpatients with CAD.12-14 Three synthetic drugs, namely sildenafil citrate (Viagra™), tadalafil(Cialis™) and vardenafil hydrochloride (Levitra™) are currentlyavailable on the pharmaceutical market for the treatment of ED. I presume you are asking about increasing the size of the erect phallus rather than asking about erectile dysfunction. I doubt icariin has even remotely comparable effects to Viagra, unless you also make sure that you optimize your lifestyle, body composition, and diet towards healthier erections. The research shows that when male rats are administered 80mg/kg of icariin, their testosterone levels increase 3-fold21, and this occurs without significant changes in LH or FSH, suggesting that icariin has a direct testicular effect on testosterone production. For these reasons, both are generously used in pre-workout supplements to increase the “pump” of the muscles and improve blood flow. Both garlic and vitamin C have been studied for their effects in promoting blood flow, reducing inflammation, and dropping blood pressure. Panax Ginseng supplements are commonly available in capsules, powders, and liquid extracts. Additionally, it has been found to reduce fatigue and improve mood, which can further contribute to better sexual performance. Ginseng is also known for its adaptogenic properties, helping the body manage stress and maintain balance. Panax Ginseng, often referred to simply as ginseng, is a well-known herb that has been used for centuries in traditional medicine. The date palm contains estradiol and flavonoid components that have positive effects on the sperm quality. They observed that the consumption of DPP suspensions improved the sperm count, motility, morphology, and DNA quality with a concomitant increase in the weights of testis and epididymis. In a study by Tajuddin et al., it was found that administration of 50% ethanolic extract of a single dose of Nutmeg and Clove, and Penegra resulted in the increase in the mating performance of the mice. Nitric oxide (NO) is considered to be the primary mediator of a penile erection and derives from two different sources. The physiology underlying penile erection is known to be a dynamic vascular process involving the relaxation of arterial and trabecular smooth muscle in the corpus cavernosum . In the present study, we observed that the most employed EI was L-arginine, which was contained in about 63% of DS formulations, but always used at an incorrect dosage (the mED is 5 g). A study published by NCBI found that men with ED and dyslipidemia saw improvements in their erectile function after taking niacin for 12 weeks. It’s known for its anti-inflammatory and antioxidant properties, which can help improve cardiovascular health—an important factor in erectile function. Thankfully There Are Natural Supplements That Help For discreet and accurate ED management and improvement, these vitamins & supplements deliver lethal results. If you notice any other effects, check with your healthcare professional. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. This includes prescription or nonprescription (over-the-counter OTC) medicines and herbal or vitamin supplements. Under the light of recent scientific researches, unsurprisingly, there exists a higher prevalence of ED among VD deficient patients compared to those with optimal levels . This may also clarify why endothelium derived; NO-evoked dilation is halved in arteries from VD deficient male rats . A placebo-controlled randomized trial demonstrated that even a single large dose of VD improves endothelial function in patients with type 2 diabetes and VDD . In molecular levels, VD stabilizes the quiescent endothelium, regulates certain stages of endothelial activation, and is involved in the repair of the damaged endothelium in vitro and in vivo models. The pathophysiology of ED is multifactorial, but common point is a vascular disorder related to decreased endothelial function. To compile this list of supplements, I examined over 25 products, and I consulted with other experts in the field, including Young, Berger, and Lemke. For more about Thorne and vitamin D, check out our full review or visit Thorne.com. However, it didn’t make our list because we were looking for a slightly higher dose of vitamin D to allow for flexible dosing to address a deficiency. Comparison of hormonal and sexual function between subjects affected and not affected by type 2 diabetes mellitus, dyslipidemia, and hypertension and with or without smoking habit in the total sample. Bivariate correlation of general and hormonal parameters with testosterone and sexual parameters at baseline in the total sample. Clinical, hormonal, and sexual characteristics of the studied sample at baseline and after vitamin D replacement therapy. Erectile function improved, whereas other sexual parameters did not change significantly (Table 1). Conventional treatments are available that may help you. If you’re one of them, you should discuss the situation with your health care provider. Testosterone levels drop with age, but medication is not your only option. Learn which supplements are genuinely worth considering and which ones fall short. These forms help improve blood flow, prevent clots, and reduce oxidative stress in the penile tissues. Vitamin D is essential for overall health and can be synthesized by your body when exposed to sunlight. Vitamin B9, also known as folic acid, plays a crucial role in the synthesis of DNA and RNA and in the production of healthy red blood cells. Adding these foods to your diet might help improve your overall health, including your ability to get and maintain an erection. Creating the best vitamins for penile growth stack was a journey.So you get the perfect blend of premium substances that hit the turbo button on your body’s testosterone production.It also plays a key role in maintaining nitric oxide levels and balancing good versus bad cholesterol.A Harvard study mentioned on Harvard Health linked E to healthier blood vessels.In animal studies, treatment with Korean red ginseng and ginseng berry extract has been shown to significantly relax the pre-contracted penile corpus cavernosum smooth muscles of rabbits in vitro, and increase the intracavernosal pressure of rats in vivo.9,10 Data from studies on ginseng berry extract suggest that this action is nitric oxide (NO) dependent.Male sexual enhancement supplements may not be safe for everyone as they can cause side effects, allergic reactions and interactions with other medications.An ounce of dark chocolate has 155 calories and nine grams of fat, so it may not be the healthiest choice among important foods to help an erection.Other side effects include headache, dyspepsia, flushing, myalgia/back pain, visual disturbances, and nasal congestion.When the smaller blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs. Consult a doctor today! When hormone levels are optimized, the body can naturally prioritize penile development. This nutrient helps the body produce testosterone, which signals tissues to expand. My experiments revealed that best vitamins for penile growth often include vitamin D. While the research on these antioxidants shows promise for sexual health, the results regarding direct effects on erectile dysfunction are mixed. In one eye-opening study of 92 men with type 2 diabetes, those with low vitamin D had more severe erectile dysfunction than men with healthy levels. When a man is sexually stimulated, his body's normal response is to increase blood flow to his penis to produce an erection. Now, there are also some supplements that can improve blood flow, improve arterial function, perhaps, and that's one kind of aspect of sexual health. Androgen receptor (AR) is abundantly expressed in male genital tissues and in spermatozoa,56 and its expression is significantly decreased in infertile men.57 Ginsenoside Rb1 and Re have been reported to be AR agonists, through which these ginsenosides stimulate NO production via the activation of NOS.58,59 Ginseng berry extract GB0710, of which ginsenoside Re is the key ingredient, could improve erectile dysfunction in rats by inducing NO production.10 Re-induced NO production in sperm has also been shown to be involved in capacitation and acrosome reaction, and that these effects could be a result of the non-genomic activities of the Re-AR interaction.40 Let’s first understand how erections work, so we can understand how vasodilators supplements help improve ED. In fact, these prescriptions can often exacerbate dysfunction in the long-term. Dividing it will allow the penis to fall away from the pubis, giving some length (a couple of centimetres), but at a loss of the normal “angle” at erection. It is possible to surgically increase the size of an erect (and flaccid, for that matter) penis, but it should not be undertaken lightly, as it is by no means guaranteed to produce the result one might be hoping for. Human studies consistently show how GSE increases NO-production and thus reduces blood-pressure, leg swelling, heart rate, and cardiovascular disease risk18–20 . Furthermore, diosgenin exerts a well-known protective effect on micro-circulation, and therefore, chronically using Tribulus could improve erectile function . Terrestris was shown to support hormonal function via the conversion of protodioscine to dehydroepiandrosterone (DEHA), which is the base molecule for the synthesis of testosterone . Moreover, many ingredients whose efficacy was demonstrated by clinical trials were dosed under the mED, raising several doubts about their real impact on sexual function. It is highly crucial to consult a healthcareprofessional if you have sexual health problems to identify the underlyingreason and create a treatment plan tailored to your requirements. By enhancing blood circulation, salmon can help supporthealthy erectile function. Improved blood flow and normalblood pressure are essential for sexual function. Dark chocolate includes flavonoids, antioxidants that canincrease blood flow and help promote healthy blood pressure. P-Long combines traction therapy, stretching exercises, AFFIRM circulation boosting supplement, and platelet growth factors in achieving natural and permanent penis enlargement. Furthermore, the fillers can cause significant complications, such as granulomas (small nodules at the site of an infection or inflammation), penile distortion, and foreign body reactions. Additionally, surgery results can be unpredictable, and some men end up with a deformed or unsatisfactory penis shape. Penile enlargement surgery involves cutting ligaments or using implants to add length and girth to the penis. While the desire for a larger penis is understandable, the available medical options have significant drawbacks. While it may be tempting to buy pills and bottles to boost your sexual performance, you might want to think twice before putting down your money. Grab The Male 90X Consult, transform your body, and reach your maximum potential today! Talk to a doctor before adding any supplements to your regimen; your doc will help choose the one that will work best for your needs. The Western diet typically doesn’t include enough of these fish, so it’s often recommended to take additional omega-3 supplements to reap the full benefits. Omega-3s work like anti-inflammatory drugs and help lower the risk of heart disease, blood clot formation, and stroke. It can therefore be hypothesized that vitamin D at high concentrations can displace the native ligands of the receptors 10, 27. In addition, activated vitamin D stimulates the production of nitric oxide in endothelial cells and nitric oxide synthases, a key process to penile vascular dilation 25, 26. Of note, the antioxidant pathway of vitamin D is also mediated by the activation of the Mek/Erk-Sirt1 axis . It is used to improve erection strength and the promotion of arterial relaxation with a boost in nitric oxide.I'm not a doctor, but my story shows how vitamins for male enhancement can complement a healthy lifestyle.A diet rich in whole grains, fruits, vegetables, nuts, and legumes is good for cardiovascular health, which is also good for increasing blood flow to the penis.NAC was part of my morning routine for clean blood flow.Blood samples for FSH, LH, total testosterone, SHBG, estradiol, parathyroid hormone (PTH), 25(OH) vitamin D, calcemia, creatinine, and albumin were taken in the morning, and their assay was carried out as previously specified 15–18.And then there's the other category of supplements that maybe can affect hormone levels. Despite there not being a strong recommendation to use DS for ED, patients are increasingly turning to alternative therapies in the hope of reducing side effects and improving their sexual performance without asking for medical help. The use of botanical extracts or other nutraceutical products to enhance male sexual performance has a long history. It is noteworthy that having trouble obtaining or keeping a satisfying erection can also be a signal of underlying health conditions that need a more in-depth investigation, such as endocrine and non-communicable diseases . A systematic review of the literature was performed to evaluate the effect of DS and to detect the active ingredients able to improve erectile function—called effective ingredients (EIs)—and their minimal effective daily dose (mED). Alternative treatments for ED are becoming increasingly popular, with growing interest from consumers, as well as increased revenue for manufacturers. When taken in excess, alcohol can increase your chances of getting a headache or dizziness, increase your heart rate, or lower your blood pressure. This condition may require prompt medical treatment to prevent serious and permanent damage to your penis. Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. This will increase the supply of blood to the lungs and reduce the workload of the heart. Why Musclespan Is The New Metric We Should Focus On Whereas, Nutmeg treated male animals mated 3 females each except 2 which mated 5 females each. It was found that out of 6 control animals only 2 males mated (inseminated) 2 females and the remaining 4 males mated 1 female each during the overnight experimental period. It was found that Crocin, at all doses, increased MF, IF and EF behaviors and reduced EL, IL and ML parameters. The aqueous extract crocin, safranal, sildenafil as a positive control and saline were administered intraperitoneally to male rats. Suchexisting remedies should be subjected to rigorous scientific scrutiny experimentally(in laboratory animals) and clinically (in humans), in order to establish theirsafety, efficacy, quality, mechanisms of action, side effects, and possibly also,their contra-indications. Recent studies in our laboratories20-22 have shown that Ekraussianum NE Br (Fabaceae) is one of the promising plant species ofSouth Africa with potential for use as an effective remedy in the treatment ofimpotence and/or ED. Unlike Viagra™, however, the bioavailability,half-life, Tmax, Cmax and other pharmacokinetic parameters ofthe bioactive compounds of E kraussianum are obscure at present.The effects of the extract on the biochemical activities of cGMP and PDE-5 are alsounknown. Each African country has acatalogue of locally made, plant-derived sexual stimulants under various local tradenames such as Impotex™, TigerPower™, SuperLove™, uBangalala™and Burantashi™. The best supplements for erectile dysfunction include L-arginine, Panax ginseng,and Tongkat Ali. Beyond vitamins, certain minerals and amino acids are absolute powerhouses for male sexual health. For your best sexual health, aim for vitamin D blood levels between ng/mL. All RCTs analyzed in this meta-analysis showed that ginseng was effective in the treatment of erectile dysfunction. The key terms used for the search were male sexual dysfunction, erectile dysfunction, impotence, phytochemical, botanicals, herbal extract, nutraceutical, dietary supplement and traditional medicine, in combination with the International Index of Erectile Function (IIEF). Researchers have found that supplementing with vitamin B12 is just as effective as supplementing with antioxidants when it comes to supporting healthy sperm count. In one study, vitamin C supplementation helped to double the sperm count of some participants. Fortunately, supplements can help correct nutritional deficiencies and boost antioxidant levels, offering protection for sperm. However, keeping a nutritious diet that contains particular nutrients can help to support general sexual health. They are the active ingredients to which the effectiveness of ginseng is attributable . Preparations based on ginseng extracts exert antioxidant, antidiabetic and immunomodulatory activity, and have aphrodisiac properties . Pycnogenol improves ED symptoms by activating eNOS, which, in turn, increases NO production and promotes vasodilation in the presence of copious amounts of arginine . At this point, cGMP inside muscle cells causes relaxation and vasodilation, resulting in penile erection. First of all, NO is produced by the neuronal enzyme NO synthase (NOS) (non-cholinergic nerve axons) of the penis and by endothelial NOS (eNOS) from endothelial cells of the corpora cavernosa . I divided my best vitamins for penile growth into AM and PM routines. A smart buy is vitamin C and E together; their antioxidant effects are stronger when combined. I found it best to take vitamins in the morning, minerals with meals, and herbs at night. Vitamin D and Zinc support testosterone production, which can help improve libido and erectile function. Vitamins primarily support erectile health and sexual performance. No vitamin has been scientifically proven to increase penis size. Nutrients like Vitamin D, C, E, B-complex, and Zinc aid hormone balance, blood flow, and tissue health. Always talk to your doctor about any sexual health problems you may be experiencing. In additions to nutrients like amino acids, vitamins and minerals, they may contain herbs, such as horny goat weed, ginseng and maca root. By law, dietary supplements must contain at least one vitamin, mineral, amino acid, enzyme, or other substance used by the body. “Don’t be afraid to bring up a sexual health concern,” says Dr. Simone. Male sexual enhancement supplements may not be safe for everyone as they can cause side effects, allergic reactions and interactions with other medications. Therefore, we aimed at evaluating the possible association between vitamin D and sexual function and at assessing the influence of vitamin D administration on sexual function. The Second Princeton Consensus on sexual dysfunction and cardiac risk stated that all men with ED, even in the absence of manifesting cardiac symptoms should be regarded as having potential risks for cardiovascular disease (24). Erectile dysfunction (ED) is a common problem and increases in incidence as men age (10). Recently, it was also demonstrated that VD supplementation improves T levels, metabolic syndrome and erectile function in middle-aged VD deficient men . Choosing the right vitamins and supplements for ED can be a game-changer in managing your sexual health. Vitamin B12 is essential for nerve health and blood cell production, and a deficiency in B12 may lead to erectile dysfunction. Some of the beneficial vitamins for erectile dysfunction include Vitamin D, Vitamin E, and Vitamin B12. These natural supplements may improve blood flow, boost libido, and support overall sexual health. Clinical, biochemical, and sexual evaluations were performed at the two time points. In our clinic, vitamin D is supplemented when its value is less than 30 ng/mL . A subsample of 41 subjects median age 65 (interquartile range 61–70) was also studied longitudinally before and after vitamin D replacement therapy. There is also an indirect risk of missing potential medical conditions in patients that bypass the healthcare system to purchase illicit PDE-5i. Other side effects include headache, dyspepsia, flushing, myalgia/back pain, visual disturbances, and nasal congestion. There are numerous known side effects of PDE-5i, some of which may be life threatening. CGMP then acts on protein kinase G to open calcium channels that leads to vasodilation and an erection. In the normal erection process, vascular endothelium releases nitrous oxide, which activates guanalyl cyclase to convert guanosine triphosphate to cyclic guanosine monophosphate (cGMP). Ongoing health issues affecting your penis also can affect other areas of your life. For men over 40 seeking to combat the symptoms of declining testosterone levels, Hunter Test provides a safe, natural, and effective solution. For men over 50 who are looking to combat the symptoms of declining testosterone levels, Prime Male offers a safe, natural, and effective solution. For men over 50, finding a safe and effective solution to increase testosterone can be a game-changer. These findings make us hypothesize that the increase in testosterone levels may not be due to vitamin supplementation and that the improvement of erectile function is not due to the increase in testosterone levels. However, in our sample, neither the rise of serum vitamin D correlated with testosterone increase, nor the improvement of erectile function correlated with the increase in testosterone levels. Consistently, Barassi et al. evaluated fifty patients affected by erectile dysfunction and reported that those with severe/complete erectile dysfunction were more frequent in the group with vitamin D levels 20 ng/mL. Interestingly, similar to our results, their findings suggest that the link of 25(OH) vitamin D with erectile dysfunction is independent of testosterone . After adjusting for comorbidities, lifestyle variables, and medication use, those with 25(OH) vitamin D deficiency had a higher prevalence of erectile dysfunction compared to those with optimal levels . While spinach offers various health benefits,there is no scientific evidence specifically linking its consumption to muscledevelopment in the penis. The most significant source ofindeed vitamin D is sunlight, although it may also be obtained in supplements,fortified foods like milk and cereals, fatty fish (like salmon), and otherfoods. “If you have sexual side effects from medication you can ask your doctor if you can change your medication. While many of these products say they can increase sexual desire or performance, it’s unclear if they are safe or actually work. Editor’s Choice: The Top 10 Health & Wellness Brands to Know GSE not only boosts blood flow into the penis, it also makes sure that your testosterone-related sex drive is strong and kicking. Better yet, one study even discovered that combining vitamin C and garlic (aka the quercetin from #1) increased NO levels by 200%! C vitamins also lower cortisol, so testosterone can flow freely and blood vessels can chill out. These have all been specially selected because of their incredible effects on boosting your body’s T-production.In addition, ginseng is found to improve the sperm quality and count of healthy individuals as well as patients with treatment-related infertility.Supplementing with Zinc typically leads to a noticeable increase in ejaculate volume (“load size”) within 2-3 weeks, improving the overall sexual experience.Even though the relaxation of the smooth muscles in the penis begins with messages sent through the nerves, nitric oxide plays a key role.Inthis part, we'll explore some essential vitamins, minerals, and foods that helppromote sexual health.For maintaining good levels, 1,000-2,000 IU daily often works well.Logistic regression analysis showed that Maca has an independent effect on sexual desire at 8 and 12 weeks of treatment.A large number of DSs containing different ingredients have been proposed for the treatment of male sexual dysfunction.Sulmaz et al. studied the effect of Satureja khuzestanica essential oil (SKEO) in male rat fertility. Studies show that vitamin C may help to increase many parameters of sperm health, including sperm count. In this article, we highlight 10 of the best vitamins and supplements for male fertility based on scientific research. Smoking can indeed reduce blood flow to the penis, and drinking toomuch alcohol can impair sexual excitement and performance. Both ED and ASCV diseases have frequently identical functional and morphologic basis 3,12.We retrospectively studied 114 men by evaluating clinical, biochemical, and sexual parameters.It’s no wonder that supplement industries have caught up to the benefits of beets and many now include beetroot extract in their pre-workout supplements.This review, while evaluating various factors that control sexual function, identifies a variety of botanicals that may be potentially useful in treating sexual dysfunction.(III) DS formulations available on the Italian market (most likely in Europe) are of poor functional quality and are mixtures of many ingredients without support from the literature.Vitamin D affects an impressively wide range of physiological functions — including male fertility.Sure they work in most cases, but it’s always good to remember that they deliver a chemical erection which your body still cannot naturally produce. Some men reported a size increase; however, complications were frequent, and none of the techniques were externally validated. In total, 17 studies on penile enhancements were reviewed, assessing a total of 21 enlargement interventions in 1,192 men, with 773 followed up after non-surgical or surgical treatment. Ding et al' study indicated that VD played a protective role of testes and testicular damage induced by diabetes, and the possible mechanism might be regulating attenuating inflammation and inactivating caspase cascade. This suggests that when 1,25-D increases above its normal range, it binds the α/β thyroid, the glucocorticoid, and the T receptors, displacing their native ligands . These actions are mostly attributed to ginsenosides, the major pharmacological active components of ginseng. If including these nine natural foods for ED into your daily diet doesn’t provide any benefits to erection quality… feel free to drop me a note on the forum and I’ll eat my hat. If we take a look at some of the pomegranate research, you quickly see why this antioxidant-rich fruit is like a godsend to hormonal health and circulation. If you’re looking for a capsaicin rich recipe, check out the testosterone boosting lamb stew on this article. Strangely enough, capsaicin seems to protect testosterone molecules from the stress caused by low-calorie diets, and high-testosterone men seem to be keen on eating hot foods. One of the mechanisms involved in this process is the physiological suppression effect of vitamin D on renin, angiotensin II, and aldosterone . In this regard, the widest study has been conducted by Farag and colleagues who performed a cross-sectional analysis of a nationally representative sample of 3390 US men aged ≥ 20 years. At bivariate correlation analysis, important variables, which changed significantly after vitamin D replacement therapy, were correlated among each other. Clinical, hormonal, and sexual parameters of the total sample are shown in Table 1. After vitamin D replacement therapy, total and free testosterone increased. In the longitudinal part of the study, the same statistical approach was adopted in order to analyze the independent relationship of the variation of vitamin D with the one of hormonal and sexual parameters. The first part has the aim of evaluating the presence of a relationship between vitamin D and erectile function. Our study considered the time points before vitamin D therapy (time 0) and the first available visit in which normal vitamin D levels were achieved. The supplements discussed in this article are not intended to treat, cure, or prevent any disease. If you purchase recommended products, services, or treatments, it may benefit CNY Fertility financially. We discuss various nutrients and dietary supplements in this article that may or may not be helpful. These results need confirmation because of their potential revolutionary approach to the treatment of sexual dysfunction. Vitamin D is important for the wellness of male sexual function, and vitamin D administration improves sexual function. Since the latest literature showed the importance of VD on erectile function, Fernandes-Lima et al investigated the effects of VD restricted diet on Wistar rats offspring penis morphology. If we consider that VD effect many tissues, VDD becomes more and more important for a healthy sexual life, in other words for erectile function. Endothelial dysfunction is a key variable in the pathogenesis of atherosclerosis and its complications, including erectile dysfunction (ED). Conversely, it must also be mentioned that two different clinical studies found that vitamin D supplementation did not affect testosterone levels in men 34, 35. In addition, a trial carried out on 165 participants (54 men) observed an increase in testosterone in the vitamin D-supplemented group, whereas in the placebo group, no significant change in testosterone was found . In the same work, treatment with all doses of 1,25(OH)2 vitamin D in the absence of LH and 10 and 100 ng/mL LH in the absence of 1,25(OH)2 vitamin D increased mitochondrial dehydrogenase activity for cultured Leydig cells . Furthermore, it has been reported that 1,25(OH)2 vitamin D is able to increase LH-induced testosterone production for both immature and mature ram Leydig cells . The penis is one of the areas where this enzyme works. Zaitsu and colleagues study Stylometry for the detection of AI-generated text. This caused a 77% decrease in average mammal biomass and a severe loss of ecosystem functionality. The study may inform future policy and practice, supporting more targeted, inclusive, and sustainable HIV responses. These supplements offer a range of benefits, from improved blood flow to enhanced libido, which can help you regain confidence and improve your relationships. If you have underlying health conditions such as heart disease, high blood pressure, or hormonal disorders, you should avoid these supplements unless approved by your doctor. It is also thought to improve erectile function and male fertility. Epimedium, commonly known as “Horny Goat Weed,” is an herb traditionally used in Chinese medicine as an aphrodisiac and to support sexual health. This makes Panax Ginseng a versatile supplement for overall sexual health and well-being. Registration of patients who attended our andrology unit for sexual dysfunctions from 2003 to the present was retrospectively reviewed. To the best of our knowledge, only three works have assessed the effect of vitamin D supplementation on sexual function, showing different results 8, 10, 11. Some evidence also suggests a possible role for vitamin D in the regulation of sexual function. Ask your healthcare professional how you should dispose of any medicine you do not use. Grapefruit and grapefruit juice may change the amount of this medicine that is absorbed in the body. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. However, elderly patients are more sensitive to the effects of this medicine than younger adults. In addition, ginseng is found to improve the sperm quality and count of healthy individuals as well as patients with treatment-related infertility. Furthermore, another human study has shown that pomegranate juice consumption increased testosterone levels by 24% on average. Citrus fruits are loaded with vitamin C and as you can see from the study above when combined with garlic they can provide very significant reductions in blood pressure, as well as increases in the artery-relaxing nitric oxide. One interesting human study showed that when garlic extract is combined with high-dose vitamin C supplement, the increases in nitric oxide (+200%) along with drops in systolic (-27mm/Hg) and diastolic (-15mm/Hg) blood pressure are massive. However, theaetiology of erectile dysfunction has been shown to have a significant impact ontreatment success and satisfaction rates, with neurogenic causes of erectiledysfunction (eg, diabetes mellitus and prostate surgery) having significantly lowertreatment success rates than psychogenic or vasculogenic erectile dysfunction.15 The availability of these PDE-5 inhibitors has provided effective and well-toleratedoral treatments for ED.5,7,15,16 Moreover, these drugs havebeen reported to improve endothelial function, 10,14 and are speculated to havevascular and myocardial protective properties.10,17 As a class, the three drugsare indicated for the treatment of erectile dysfunction only. Clinically known aetiologies of ED include organic, psychogenic and combinedorigins.1 Cardiovascular disorders anddiabetes mellitus are known to contribute significantly to erectile dysfunction oforganic origin.6,8 Organic causes of erectile dysfunction are found in 80–90% of ED patients,and these include vasculogenic (ie, arterial, cavernosal and mixed), neurogenic,anatomical and endocrine causes.4 Psychogenic forms of ED are usually due to sexualperformance anxiety, depression and inhibited sexual drive.4 If our data will be further confirmed, vitamin D evaluation might be included in the near future in the clinical work-up protocol of male sexual dysfunction. In conclusion, to be effective, a DS should be well-designed to act both acutely on the production of nitric oxide (locally in the penis) and chronically by normalizing the hormonal framework. Furthermore, we can hypothesize that some dietary supplements contain unverified ingredients, thus altering the real effect of marketed products. (III) DS formulations available on the Italian market (most likely in Europe) are of poor functional quality and are mixtures of many ingredients without support from the literature. In the majority of cases (757 of 776 (97.6%)), supplements contained ingredients that were not declared on the label. Somnifera is not useful in the treatment of organic ED. Too much aromatase causes estrogen dominance that can kill your sex drive and lead to low testosterone symptoms.Smoking can indeed reduce blood flow to the penis, and drinking toomuch alcohol can impair sexual excitement and performance.Prime Male’s formula comprises twelve potent ingredients, all backed by scientific research and specifically selected to support healthy testosterone levels in older men.Also, this does not lengthen the skin, and so the peripenile pubic skin is often pulled onto the shaft of the penis, resulting in pubic hair growing from the penile shaft.Researchers from King’s College Hospital NHS Foundation Trust and King’s College London have reviewed the use of surgery and other treatments to enlarge penis size.It contains a compound called icariin, which may enhance libido and erectile function.Together, vitamin C produces and maintains NO for longer, stronger erections. No complementary health approaches have been shown to be safe and effective for sexual enhancement or treating ED. Effective medical treatment for ED is available only through a health care provider. Learn what works, what does not, and what habits to avoid if you are serious about improving your health and energy levels. Maybe if you have high blood pressure, there are a couple of supplements you could look at. Testosterone is the principal male sex hormone which affect libido, muscle mass, energy, and sexual functions. Erectile function relies heavily on testosterone, which vitamin D is known to help keep balanced. If individuals have deficiencies in vitamins they can experience sexual other problems On the other hand, longitudinal evaluation of our study clearly shows the improvement of erectile function after vitamin D replacement therapy, also demonstrating the direct influence of the vitamin D treatment. Furthermore, in a particular case series of 37 dialysis patients, the ASEX total score was found to be negatively correlated with serum 25(OH) vitamin D level, thus demonstrating that sexual dysfunction is related to low serum 25(OH) vitamin D levels . Our cross-sectional study shows that vitamin D levels are directly able to influence all sexual function parameters. In the transversal part of our study, in order to analyze the independent relationship of vitamin D with testosterone levels and sexual parameters, a two-step approach was adopted.