If necessary, we will contact the authors of the included studies and the researchers in the field to identify ongoing and unpublished studies. All prospective clinical trials including randomized clinical trial, controlled trials, and uncontrolled observational studies. The objective of this systematic review is to determine whether ginseng is effective in improving sperm quality. GBE enhances testosterone synthesis in the mice blood serum Furthermore, this model’s effect on serum testosterone levels and hypogonadism has previously been demonstrated . However, similar in vivo models have equated aging with stress burden; in our study middle-aged or older mice were exposed to acute mental and physical stress of paradoxical sleep deprivation through a modified muti-platform method, previously defined for rat . However, given that the androgenic steroid production increased on the cellular level, along with the direct evidence of the improvement in testes volume, it can be confirmed that GBE improves serum testosterone levels. The results showed that GBE administration improved mouse serum testosterone levels. GB0710 and KRG extract were added to the resting equilibrated muscle strips for the evaluation of their relaxation effects under basal conditions. KRG, Korean red ginseng; Rb1, ginsenoside-Rb1 (C54H92O23); Rb2, ginsenoside-Rb2 (C53H90O22); Rc, ginsenoside-Rc (C53H90O22); Rd, ginsenoside-Rd (C48H82O18); Re, ginsenoside-Re (C48H82O18); Rg1, ginsenoside-Rg1 (C42H72O14); Rg2, ginsenoside-Rg2 (C42H72O13). Red ginseng (Panax ginseng, CA, Meyer), cultivated and manufactured in Chungbuk province in Korea was added to ethanol and extracted under reflux. Various herbs have been used by people of different cultures to treat conditions of male infertility or for treatment of reproductive disorders. Terrestris extract increased the levels of T, DHT, and DHEAS and that the effect was more pronounced in hypogonadal state. It supports nitric oxide production and vascular health, improving erectile function naturally rather than acting as a direct phosphodiesterase inhibitor. Improvements in erectile function can be observed within 4 to 12 weeks of consistent use, depending on individual health and dosage. Its active compounds, ginsenosides and gintonin, help increase nitric oxide, improve blood flow, support healthy blood vessels, and reduce stress. To date, the mainstream of research linking dietary ginger to testosterone has revealed that ginger or ginger extracts have an impact on testosterone as testosterone production was enhanced upon ginger supplementation. Therefore, the results presented in this study were reliant on only in vivo system studies. Thus far, all studies that have found a direct link between ginger or its derived compounds and testosterone were in vivo system studies, and no human studies were conducted in this specific research context. Hong et al. (2002) conducted a double-blind crossover study which included 45 patients with ED.Ginseng is a root that has been used extensively in traditional Chinese medicine for thousands of years.American ginseng contains unique ginsenosides that help the body adapt to stress (adaptogenic properties), support mental clarity, and promote sustainable energy without the stimulating effects that can disrupt sleep or cause jitteriness.Siberian ginseng has fatigue-fighting and vitality-boosting properties.This integrated approach to male health—addressing vitality alongside sleep, digestion, stress management, and prostate health—represents the true spirit of TCM's holistic philosophy adapted for modern wellness needs.The use of food and herbal supplements to enhance erectile function as well as sexual arousal and desire has become increasingly popular in the recent years 1, 2.But even if you disregard animal studies and only look at the competition, you’ll find a 1,000mg cordyceps dose in Max Performer, which greatly eclipses Male Extra’s offering.Whether you're looking to boost energy levels, support reproductive health, or enhance overall vitality, these natural solutions offer promising benefits backed by centuries of use and emerging scientific evidence. Animal and clinical investigations suggest regular use of Panax ginseng can enhance spermatogenesis, support fertility, enhance libido, and increase erectile function.1 The herb may also improve sperm survival rate, motility and quality.1 In rats, Panax ginseng has been shown to protect testicular Leydig cells from suppression by dexamethasone (a synthetic glucocorticoid), thereby protecting or restoring diminished testosterone synthesis.2 Those herbs that boost DHEA and androgens, such as Epimedium, Eurycoma, and Tribulus, might be combined with the classic adaptogens and used for men with erectile dysfunction that presents along with loss of muscle mass and general vitality. In practice, the herbs which improve circulation, such as maca and small amounts of yohimbe, might be used for those with erectile dysfunction due to vascular weakness. There’s currently no research comparing different productions or types of ginseng as erectile function medicines. Okay, but what about erectile dysfunction? Validity assessment was performed by two reviewers, which reduced the risk of bias and error; it was not clear whether similar steps were taken for study selection. Publication bias was a possibility as no attempts to identify unpublished studies were reported. The research question was supported by inclusion criteria for participants, intervention and study design and outcomes. Panax ginseng is a plant that can be found throughout the Asian region, in Korea, northeastern China, and eastern Siberia. Innerbody uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Still, they can actually produce results that no male enhancement pill can claim.37 Ginseng is reputed for its efficacy in supplementing erectile function as an aphrodisiac. That said, refrain from taking ginseng supplements without proper consultation with a men’s health specialist. Its positive effects on stress management, for instance, are still something that’s being studied. Although research about ginseng’s effects has been well-studied, there’s still more to uncover about this medicinal root. Studies have shown that ginseng can increase sperm count, motility, and quality, which are all important factors for fertility. It contains active compounds called ginsenosides, which have been found to relax the smooth muscles and promote the release of nitric oxide, a molecule that helps dilate blood vessels. It's easy to add to your diet and can be consumed in various forms such as capsules, teas, or extracts. Ginseng is a popular herb that has been used for centuries in traditional Chinese medicine. The commercial product Chonbo-204® has been registered as the patent name of an herbal formula for improving penile erection with lasting effects, and is available as small tablets prepared with a water-extracted mixture. This product was developed as a health supplement by the Korea Bio Medical Science Institute, which is developing oriental herbal medicines (Table 1, Fig. 1). No clinical data have been reported on the effect of garlic on improving erectile function, although garlic has been used for ED due to word of mouth. Male silkworm extract was found to produce mild adverse effects such as digestive difficulty, sputum production, temporary chest palpitations, drowsiness, and increased stool frequency . Pregnant or breastfeeding women, individuals with certain medical conditions, and those on specific medications should consult their healthcare provider before using ginseng. While ginseng is generally considered safe for many people, it may interact with certain medications and have potential side effects. Here are a few potential ginseng side effects that some people may experience. The recommended dosage of ginseng may vary based on factors such as age, health status, and individual response. Ginsenosides have demonstrated anti-inflammatory effects in some studies, potentially contributing to inflammation reduction in the body. It’s packed with ginsenosides, unique compounds that are thought to be responsible for its health benefits. It’s an adaptogen, which means it helps your body resist the effects of stress. Often called Panax ginseng, red ginseng is a plant native to Asia that’s been dried and steamed for medicinal use. Cistanche tubulosaethanol extract mediates rat sex hormone levels by induction of testicular steroidgenic enzymes. Effects of Cistanche deserticola extract on penis erectile response in castrated rats. ANOVA, analysis of variance; b.w., body weight; KGC04P, Korean Red Ginseng–water extract; HC, heat-stressed control; HK100, heat-stressed and received KGC04P 100 mg/kg b.w.; HK200, heat-stressed and received KGC04P 200 mg/kg b.w.; NC, normal control; S.E.M, standard error of the mean.This mechanism helps explain its traditional use for supporting male sexual function.A standard scoring system was used to quantify the likelihood of bias inherent in the studies based on the description of randomization, blinding and withdrawals.In addition, we evaluated the possible mechanisms of the action of GB extract.Mechanism of the therapeutic effect of red ginseng on erectile dysfunction.Ernst et al. (2011) also arrived at a similar conclusion as Khera and Goldstein (2011) where the experts concluded that Panax ginseng was the only herbal supplement test that received a cautiously positive conclusion without apparent safety issues . However, the effects and appropriate dosages can differ for older adults or those with certain health conditions. Always consult with a healthcare professional before making any changes to your treatment plan. Ginseng can affect blood sugar levels, so if you’re on diabetes medication, you need to monitor your blood sugar closely. By contrast, group III showed significantly reduced reactivity, demonstrating the effects of KRG, which reversibly improved fibrosis in the corpus cavernosum penis. NO interferes with the adhesion of platelets and white blood cells to the blood vessel wall and reduces smooth muscle cell proliferation.9 High blood glucose induces the glycation of the corpus cavernosum penis and inhibits the regeneration of collagen fibres. For instance, high blood glucose facilitates the production of reactive oxygen species, such as superoxide anion, to inactivate NO and increases free radicals, which activate protein kinase C and various cellular factors. Two reports are similar to our study and were designed using an animal model of metabolic syndrome. Many over-the-counter male enhancement pills are classified as dietary supplements, meaning they are not subject to the same rigorous testing and approval process as prescription medications. This ensures a personalized approach that considers individual health needs and potential interactions with existing medications. Therefore, it is advisable for individuals to consult healthcare professionals before starting any supplement regimen. The lack of rigorous testing and regulation means that some supplements may not deliver the promised results or could even pose health risks. Many users report positive experiences with specific products, often citing improvements in libido, stamina, and overall sexual satisfaction. There are different ways in which a person can take health supplements that take advantage of ginseng extract.A variety of plants have been used as sex stimulants or sexual performance enhancer in traditional systems of medicine of various countries 4–6.Further, many supplements exist that will provide you with a combination of different ginseng extracts.It has also been found to reduce the risk of erectile dysfunction and improve overall sexual performance.None of the included studies reported the details of allocation concealment and were therefore rated as having an unclear risk of bias.It’s also important to purchase ginseng supplements from reputable sources that use quality control measures to ensure purity and potency.There is solid research, stretching back to the 1970s, showing that Panax ginseng promotes optimal sperm quality.The advantageous influence of Panax ginseng on oxidative damage induced by AGEs suggests that ginseng downregulates RAGE expression, consequently inhibits NF-κB activation109.Adaptogenic properties support energy, libido, and hormonal balance without altering testosterone directly.Ashwagandha has apparent effects on testosterone production, but it’s also remarkably good at regulating stress and anxiety. Somnifera, which had literature supporting the improvement of functional hypogonadism or late-onset hypogonadism (LOH), were poorly taken into consideration by manufacturers. Among the EIs, L-arginine was the most used ingredient, followed by Tribulus terrestris and Panax ginseng. Yohimbe extract were not considered in the evaluation of the expected efficacy of the various commercial formulations. In detail, six EIs with evidence of efficacy were supported by at least two RCTs, namely, Eurycoma longifolia, Panax ginseng, L-arginine, Corynanthe yohimbe, Tribulus terrestris and Pinus pinaster. Most of the studies reviewed included patients with various causes of ED. Top Reviews Vernet, D., Cai, L., Garban, H., Babbitt, M.L., Murray, F.T., Rajfer, J., et al. (1995) Reduction of Penile Nitric Oxide Synthase in Diabetic BB/WORdp (Type I) and BBZ/WORdp (Type II) Rats with Erectile Dysfunction. (1995) Clinical Efficacy of Korean Red Ginseng for Erectile Dysfunction. (2017) Erectile Dysfunction in Young Men—A Review of the Prevalence and Risk Factors. ExtenZe was one of the first male enhancement pills to gain national attention. On the one hand, it can be difficult to differentiate among them or to understand why the company produces so many versions of male enhancement products in the first place. There are no freebies included at bulk purchasing levels like e-books or other products. Conversely, 1,000mg of ginseng is less than you’ll often see in clinical research. A 1,000mg dose of cordyceps reflects successes seen in some animal studies. Panax ginseng nanoemulsion for counteracting male infertility via modulating sex hormones and oxidative stress in a rat model. Importantly, the beneficial effect of nanoemulsion of Panax ginseng dry extract surpasses that of free Panax ginseng dry extract, resulting in a superior mitigation of BPA-induced male infertility. According to our knowledge this is the first study for development of Panax ginseng dry extract nanoemulsion by oil in water (O/W) method. Therefore, the nanoemulsion of Panax ginseng dry extract proved to be the superior treatment. Erectile dysfunction is a common issue affecting many men, and natural remedies like ginseng have gained attention for their potential benefits. Physician should have low threshold in prescribing for erectile dysfunction medication and to carefully monitor patients who are at risk of developing ED in the future to encourage more open conversation about this topic and eliminate the stigma of ED. Strict guideline and regulations for erectile dysfunction supplements should be implemented to prevent misuse of medications such as Sildenafil or Tadalafil or medications similar in structure. During initial assessment, patient reported he has been abusing over the counter erectile dysfunction (ED) pills since last ten (10) years which he purchased over the internet and from the local grocery stores, with the majority being labeled made in China. Clinical trials of the effects of red ginseng on men’s reproductive health Panax notoginseng is planted mainly in Guangxi province and Yunnan province of China. It was showed that some Kaempferia parviflora rhizome extracts, especially the 5,7-methoxyflavone, had inhibitory activity against PDE5 (34). Neferine is an extract from the embryo of lotus seeds, which is used as a sedative, antipyretic and hemostat agent in TCM. Ginseng, particularly Panax ginseng, offers a natural alternative that might be appealing to those looking for fewer side effects and additional health benefits. Due to the decreased oxidative stress, the blood vessels’ health is preserved, and ED is improved by ginseng. For instance, oxidative stress is recognized to have adverse effects on endothelial function and the latter is critical for erectile function. Explore its effectiveness in treating erectile dysfunction and usage. While other supplements may solely focus on hormonal health, ginseng offers additional benefits like immune support and stress relief. Metabolic syndrome may cause vascular endothelial dysfunction through multiple pathways. These rats had significantly higher MDA levels and significantly lower GSH levels than normal rats, but these outcomes were reversed after RG treatment . Testosterone is essential for the function and maintenance of the structure of the male secondary gonads and is related to spermatogenesis 75, 76. The impaired expression of these genes induced by doxorubicin, aging, subchronic intermittent immobilization stress, and heat stress can be reversed by RG, restoring spermatogenic function in rat testes (Fig. 2) 29–34, 42–45. Adaptogenic Benefits of Siberian Ginseng for Men’s Health One study on muira puama assessed the efficacy of a commercially available supplement containing muira puama and gingko in improving libido and anorgasmia in 202 postmenopausal women. There is limited additional literature to suggest maca is an effective supplement in ED treatment. Studies on the usage of maca for sexual enhancement are limited, and to date there is no clearly understood mechanism of action. However, you may have heard of Panax ginseng because of its supposed ability to treat erectile dysfunction. The natural world is replete with natural treatments for erectile dysfunction. Scientifically, studies have shown that Epimedium may restore low levels of both testosterone and thyroid hormone, bringing low levels back to their normal levels (5), which may account for some of its benefits in improving sexual libido. More importantly, pumpkin seed ingestion can impact prostate health, which is very important for male sexual health. Men need more zinc than women, especially for sexual functionality and prostate health (19). Like ginseng, this plant is employed to increase strength, libido and sexual function (14). Thus, Sexual performance in the male has an unprecedented importance depending on the erectile function of the male sex organ. This approach aligns perfectly with contemporary understanding that male health depends on interconnected factors including hormonal balance, stress management, circulation, and cellular energy production. Warfarin (Coumadin) interacts with Panax Ginseng Recent investigations explore combinatorial effects of phyto‑flavonoids (e.g., Hawthorn extract) with traditional vasodilators, aiming to synergize NO production and antioxidant protection. Early-phase trials indicate potential additive benefits, but larger, double‑blind studies are pending. A 2025 randomized trial of a ginseng‑rich private label pill demonstrated reduced markers of oxidative stress (malondialdehyde) and modest improvement in penile Doppler flow, yet the effect size was modest (Mayo Clinic Proceedings). Researchers have found that 900 mg of P. ginseng three times daily is effective for erectile dysfunction. A systematic review of randomized studies published in the Journal of Ginseng Research in 2013 found that Korean red ginseng had effectively increased sexual arousal and general health and well-being in menopausal women. At the five-day mark, ginseng extract had significantly reduced fasting blood sugar levels, while at the end of the study, overall blood sugar levels were reduced by 53%. A 2013 study also found that Korean red ginseng improved insulin sensitivity, and this is further evidence that ginseng can help reduce blood sugar levels and help treat type 2 diabetes. Another study published in the Journal of Psychopharmacology in 2006 found that P. ginseng lowers blood sugar levels one hour after consumption when ingested without sugar, which demonstrates the glucose-regulating effects of ginseng. L‑citrulline, a metabolic precursor to L‑arginine, may offer superior bioavailability, sustaining plasma arginine levels longer than direct supplementation (PubMed, 2023). Research interest has risen because the blend of vasodilators, hormonal modulators, and antioxidants aligns with known determinants of erectile physiology, yet rigorous head‑to‑head trials are still limited. Private label male enhancement pills single card are one such category that has attracted scientific curiosity, though the evidence base varies widely. Korean red ginseng is often recommended for improving sperm production due to its potential to enhance reproductive function. By adopting a holistic approach that includes ginseng supplementation as part of a healthy lifestyle, individuals can support their sexual health and overall well-being. Seeking medical advice and treatment for these conditions is essential for optimizing sexual health. Conditions such as diabetes, high blood pressure, and obesity can impact erectile function and libido. Ginseng, specifically Panax ginseng, is a renowned herb with adaptogenic properties, traditionally used in Chinese and Korean medicine for thousands of years. Mechanism of the therapeutic effect of red ginseng on prostate diseases. The present review aimed to examine the effects of RG treatment on MRH. Doctronic is not a doctor, does not provide medical advice, does not practice medicine, and does not provide patient care. While modern medicine often focuses on treating specific conditions, TCM takes a holistic approach, viewing male vitality as part of a complex energy system that can be balanced and enhanced through specific herbs and practices. A Botanical Blend for Nitric Oxide (NO) ProductionThis formula also includes an award-winning botanical blend that supports the production of nitric oxide - the body's "on switch" for healthy blood flow and circulation. It combines botanicals especially chosen for supporting libido, performance, stamina, satisfaction and healthy circulation and blood flow throughout the body. Remember to keep your healthcare provider informed about any new treatments you’re considering to ensure they’re safe and appropriate for your situation. Effect of wild ginseng on scopolamine-induced acetylcholine depletion in the rat hippocampus. Comparison of ginsenosides Rg1 and Rb1 for their effects on improving scopolamine-induced learning and memory impairment in mice. Effect of ginseng saponins on beta-amyloid-suppressed acetylcholine release from rat hippocampal slices. Risks and Side Effects of Taking Ginseng This was demonstrated by analyzing TM3 cell cultures, to assessing the survivability and serum production in the living animal, and finally, evaluating the survivability and health of the animal under acute stress situations. However, serum testosterone levels and its production have long been considered its central thesis of definition . While difficult to properly identify in its symptomatic context, it is generally defined as ‘loss of vigor’, often categorized by descriptive axes of sexual function, social activity, and physical robustness 17,22. To further confirm, we performed a sleep deprivation study on mice, with or without GBE treatment. The testosterone levels were significantly increased in the GBE-fed group (50 or 100 mg/kg) when compared to the LPS-injected group (Fig. 12). Dr. Ritu Thakur is a healthcare consultant based in Delhi, India.Third, we did not consider a menstrual cycle of participants in this study.A study published in the Asian Journal of Andrology (2007) recruited 60 patients with mild or mild-to-moderate erectile dysfunction and gave them either 1,000 mg of Korean red ginseng or placebo daily.It helps stimulate testosterone production, improve libido, and enhance sexual performance by increasing nitric oxide levels, which promote better blood flow.Characterization of red ginseng-drug interaction by CYP3A activity increased in high dose administration in mice.They can also be used to treat sexual disorders such as erectile dysfunction, a condition that’s loosely defined as the persistent inability to get or maintain an erection.Effects of topically applied Korean red ginseng and its genuine constituents on atopic dermatitis-like skin lesions in NC/Nga mice. However, one of the most notable uses of this potent herb is boosting the reproductive system in males. There are many varieties of ginseng, such as Asian ginseng, South China ginseng and American ginseng, depending on the presence of ginsenosides and gintonin. If you are a Mayo Clinic patient, we will only use your protected health information as outlined in our Notice of Privacy Practices. Sign up for free and stay up to date on research advancements, health tips, current health topics, and expertise on managing health. At worst, surgery can cause complications such as infection, scarring, and loss of sensation or function. Whether consumed as a brewed tea, incorporated into soups, or encapsulated in concentrated extracts, its versatility knows no bounds. Mechanistic studies elucidate its mechanisms of action, shedding light on its multifaceted impact on human physiology. Its adaptogenic properties are believed to help combat stress, fatigue, and enhance endurance. Today's lifestyle challenges—chronic stress, environmental toxins, sedentary work, poor sleep quality, and processed diets—create unique obstacles to maintaining male vitality. Instead, practitioners carefully combine herbs into formulations that maximize benefits while minimizing potential side effects—a practice reflected in products like Cool Man™, which combines multiple vitality-supporting herbs. Additionally, Maca provides nutritional support with a rich profile of amino acids, fatty acids, vitamins, and minerals that serve as building blocks for optimal male physiological function. Maca root, while originating from the high Andes of Peru rather than China, has earned its place in modern TCM-inspired formulations like Cool Man™ thanks to its remarkable adaptogenic properties and specific benefits for male vitality. You’ve probably seen numerous names for ginseng on supplement labels.However, one must realize that good erections don't just happen by chance, but rather thanks to good health and generous blood flow.The antimicrobial compounds in ginseng extracts help protect against viral and bacterial infections.By combining Epimedium, American Ginseng, Cynomorium, Morindae officinalis, Tongkat Ali, Lycium barbarum, and Maca, Cool Man™ delivers a balanced approach to male vitality that addresses multiple physiological pathways simultaneously.Infertility impacts approximately 15–20% of couples globally, with a male factor contributing to around half of these instances3.The herbs and tonics act as or as “pick-me-ups” and energizing tonics which help the tired and fatigued male and those with sexual asthenia.If you still don’t have the desired effect, ginseng may not be effective for you, and you may need to look for answers elsewhere. A 2008 study found that Panax ginseng significantly improved erectile function and libido in men with erectile dysfunction (ED). Mechanism of the therapeutic effect of red ginseng on erectile dysfunction. Research has shown that ginseng is highly effective for men’s health, particularly in boosting energy, brain function, and testosterone levels. Purported benefits include its aphrodisiac effects, improvement of sexual dysfunction in men, and its antihyperglycemic effects when used to treat diabetes. You should consult your doctor if you’re experiencing persistent erectile dysfunction, as it can signal underlying health issues that need attention. Testicular weight is an important anatomical indicator of the fertilization ability of males 61,62. It is well-known that the vasodilation effect of NO increased blood flow in the blood vessels 58,59. In addition, Streptozotocin-induced diabetic rats treated orally with 500 mg kg−1 of ginger extract daily had lower glycated hemoglobin (HbA1C) compared to a control group . It has been shown that dietary supplementation of ginger roots prevented the decrease in glutathione S-transferase and GSH level thereby resulting in a reduction in prooxidants, which may subsequently enhance the synthesis of testosterone . The decrease in GSH level reduces the detoxification process for prooxidants in the testes, which negatively affects the testosterone production . Since 1991, various in-vivo, as well as basic research studies, have discovered a link between ginger (Zingiber officinale) and testosterone. Several in vivo trials have utilized different dietary supplements and medicinal plants to enhance testosterone production in males. Enhancing and protecting testosterone production is one target for many scientists because of its crucial role as a primary sex hormone in males. Ginseng is also great for men who are looking to improve their wellness and sexual function. Adequate testosterone levels are important for libido, overall sexual function, and mood. It is known to improve overall health and is particularly noted for its potential effects on erectile function. In this article, we will explore the mechanisms by which ginseng can aid in sexual health, alongside other natural remedies that may contribute to restoring function. Furthermore, present results reported that long-term administration of ginseng in obese patients improved HDL level while cholesterol level was decreased . Another animal study showed that saponins as GS promote the synthesis of LDL receptors in rats, thus increasing LDL receptors. Higher levels of HDL appeared to be beneficial as it carries cholesterol away from tissues to the liver, where it can be excreted. The lipid profile in ED patients predominantly shows high levels of total cholesterol/high-density lipoprotein (TC/HDL) and low levels of high-density lipoprotein (HDL). Lastly, it’s crucial to address any underlying medical conditions that may be contributing to sexual dysfunction. A balanced diet rich in fruits, vegetables, lean proteins, and whole grains is essential for overall health, including sexual function. While ginseng may offer benefits for male enhancement, it’s essential to emphasize that it’s not a miracle cure. This is possible as long as one of the main ginseng plant species are used. The combination of chemicals that are found in ginseng is very similar among many of the plant species that have been identified. This particular species of these plants are often referred to as white ginseng as well. Panax ginseng may also have antioxidant and organ-protective properties that are thought to increase the production of nitric oxide (NO) in the blood vessels of the penis. It is commonly used to strengthen the prostate gland and promote healthy hormone function in men. Its effect on hormonal levels has been applauded by many; and, as a tonic for the body’s well- being, it is believed to have great benefits (5). You’ve probably seen numerous names for ginseng on supplement labels. As such, it’s often found in dietary supplements and herbal medicines as part of a “blend.” There’s technically a third king of ginseng from Siberia. It has been found to increase the production of nitric oxide, which is a molecule that helps to dilate blood vessels and improve blood flow. It has been shown to have a positive impact on various aspects of the cardiovascular system, including blood pressure, blood flow, and circulation. However, it’s believed that ginseng may work by improving the body’s ability to produce and utilize energy. Research has shown that ginseng may help to improve physical endurance and reduce feelings of fatigue. Outcome measures included both self-reported symptomatic improvement as well as pre- and post-treatment International Index of Erectile Function (IIEF) scores. Both compounds are reported to increase nitric oxide (NO) synthase activity and facilitate blood flow to the penile corpora cavernosa . Ginseng is composed of biologically active compounds called ginsenosides and ginseng saponins. Daily food intake was increased but body weight gains in ginseng treated group was lower than that of the control, 28% less in 1% group and 21% less in 5% group.Also, ginsenoside Rg1 decreased left ventricular hypertrophy, and P. ginseng inhibited apoptosis in cardiomyocytes by modulating Bcl-2 and caspase-3 during ischemia and reperfusion , .In all, 119 men with mild-to-moderate ED participated in a multicenter, randomized, double-blind, parallel, placebo-controlled clinical study.Also, total saponin, panaxadiol, and panaxatriol protect against ischemia and reperfusion injuries .However, currently, there is a lack of systematic review of these studies, although a few reviews tend to report the efficacy and safety of Korean RG in male diseases by meta-analysis .There are various treatments available for erectile dysfunction, including medications, therapy, and lifestyle changes.The erectile function in men with previous signs of erectile dysfunction was improved.Its potential lies in its ability to promote nitric oxide synthesis, which aids in relaxing blood vessels and improving blood flow to the genital area. Companies offer many types of nonsurgical penis-enlargement treatments. Get the facts about what to expect from male-enhancement pills, pumps, exercises and surgeries. To further clarify the effects and clinical application of Chinese herbs and herbal formulas, well-designed RCTs need to be conducted. However, few basic studies have been performed to investigate their mechanisms up to now. Shuganyiyang capsule is a formula composed of 15 Chinese herbs, which could increase blood circulation, activate Yang and replenish vital essence of human bodies. Another benefit of ginseng is its ability to strengthen your immune system and fight off infections and disease.Possible reasons behind such a risky behaviour include (a) the embarrassment to speak with a doctor, (b) the thought that buying them online would be the fastest and cheapest way to solve the problem, (c) curiosity, (d) peer-pressure, and (e) the increase of sexual confidence and performance .No differences or statistically meaningful results were observed from the blood chemistry analysis.Results can vary based on the individual, but typically, you might start to notice effects after a month of consistent use.Park JS, Hwang SY, Lee WS, Yu KW, Paek KY, Hwang BY, Han K. The therapeutic effect of tissue cultured root of wild Panax ginseng C.A.This is a secure Internet-based early warning system that gathers preliminary reports of public health significance by monitoring global media sources near “real-time,” 24 hours a day, 7 days a week basis.That depends on the quality of the ginseng, an individuals’ level of healthy gut bacteria, and the quantity of compounds in the ginseng that you start with. These effects are likely why ginseng has accumulated a reputation as a powerful herbal aphrodisiac. The mechanism at play here is an increase in blood flow, thanks to the vasodilating properties of ginseng. Auragin provides a strong dose of ginseng, and carefully measures the concentrations of ginsenosides (the biologically active ingredient responsible for ginseng’s benefits). It’s also important to speak with a healthcare provider before taking any supplements, as they may interact with other medications or have potential side effects. A study published in the Journal of Urology found that men who took a ginseng supplement had increased sperm count and motility compared to those who did not take the supplement. However, it’s important to note that men did not report enhanced sexual desire or satisfaction in the same study. According to the American Academy of Family Physicians, taking 900 mg of red ginseng three times a day may improve erections. Ginseng was among Emperor Shen-Nung's notable contributions to herbal medicine. Demand for ginseng outstripped its supply, and in the 16th century Korea experimented and cultivated the first farmed root, creating a lucrative trade in the root to China and beyond. Diggers, illegal traders and robbers would raid live ginseng stock to sell on the produce in a black market trade. We presented details of included studies in the Characteristics of included studies table, baseline characteristics of included studies (Table 2) and description of interventions (Table 3). The process of selecting the eligible studies is shown in the PRISMA flowchart (Figure 1). We identified two studies awaiting classification but no ongoing trials. Specific conditions ginseng has been advocated for include depression, anxiety, chronic fatigue syndrome, the treatment of hepatitis C, diabetes mellitus and hypertension. Treatment claims with ginseng are numerous and an overriding principle exists where ginseng supports one's overall health and boosts the immune system by channeling the body's energy to areas that require it for healing. Modern-day studies have shown that the root of these two most commercially obtainable Panax ginseng species have been found to contain more than 30 ‘ginsenosides’ or active compounds. Erectile function and overall satisfaction scores after medication were significantly higher in the TMGE group than in the placebo group (P However, the effect of ginger or ginger extracts on testosterone is not yet confirmed in humans. Supplemental zinc can both boost serum testosterone levels and improve hypogonadal symptoms in men with zinc-poor diets. Zinc, however, is commonly included in dietary supplements targeted at improving overall sexual function. Nguyen et al. studied its safety profile and efficacy in treating ED in 54 middle-aged men given Revactin® twice daily, with erectile function assessed every month using the IIEF. While they share the “ginseng” name, they are different plants with different active compounds and, consequently, different effects, especially concerning men’s health. Despite all the health benefits that ginseng has, not all ginseng is created equal! In addition to regulating blood sugar levels, ginseng can also help improve mental clarity and focus. Therefore, although preclinical studies showed an efficacy of ginseng supplements on physical performance enhancement, clinical circumstances could report no benefit of ginseng supplements. However, although there are some possible biological mechanisms on the efficacy of ginseng supplements on physical performance enhancement in in vivo animal or in vitro laboratory studies, our meta–analysis of eight randomized controlled trials found that there was no sufficient evidence on the efficacy. A clinical experimental study reported that the use of ginseng supplements before exhaustive aerobic exercise can reduce creatine kinase leakage during exercise, possibly due to ginseng's ability to reduce cellular and muscle damage (40). An in vitro study suggested that ginseng increases energy produced aerobically in the brain (32). Wiklund I, Karlberg J, and Lund B. A double bind comparison of the effect on quality of life of a combination of vital substances including standarized ginseng G115 and placebo.These factors can make sexual activity less interesting leading to erectile dysfunction.Aswar et al. compared the effects of fenugreek extract on testicular development in sexually immature rats.Thus, there is a need for a well‐organized and up‐to‐date systematic review to evaluate the efficacy of ginseng for erectile dysfunction.There are some medicines left in your cart, You want to save these before leaving?Furthermore, the use of red ginseng also seems to offer men the ability to experience an improvement in their libido.This ensures that you can enjoy its benefits without compromising your health.However, not everyone who uses the Panax ginseng supplement is bound to experience these side effects because people’s health needs are different and people also react differently to supplements. Terry Naturally Red Ginseng Male Sexual Enhancement 48 caps Before starting ginseng, it's important to understand potential side effects and interactions. For example, combining 200mg of Panax ginseng extract with 6g of L-citrulline malate has shown promising results . Pairing ginseng with other natural compounds can boost its effects. The fully completed systematic review will provide a summary of the current state of evidence regarding the effectiveness of the ginseng for sperm parameters. Currently, no systematic review of ginseng for improving sperm quality exists. We will conduct the test for funnel plot asymmetry using Egger's method if more than 10 studies are included in the meta-analysis. If we cannot perform a meta-analysis due to the clinical and methodological heterogeneity of the included studies, the findings of the review will be presented as a descriptive synthesis. We will use a 50% cut-off point for meaningful heterogeneity among the included studies. A study published in the Journal of Ginseng Research found that taking ginseng supplements for 8 weeks helped reduce body weight, body mass index (BMI), and waist circumference in obese adults. Ginseng has been shown to help regulate blood sugar levels in people with type 2 diabetes. It is also important to follow the recommended dosage on the label and to talk to a healthcare provider before taking ginseng if you have any underlying health conditions. After reviewing his medication, the doctors determined the only major change had been an introduction of a ginseng supplement. A 47 year old man with heart disease had abnormal blood markers of clotting at one of his regular check-ups. Notably, she had a known mood disorder before she started taking ginseng. Even though the science behind ginseng is not bulletproof, the good news is that ginseng appears to be a pretty safe supplement. Panax ginseng extract has shown the ability to improve sexual function in men through different mechanisms. For instance, Korean white ginseng preparation is done by drying while Korean red panax ginseng extract is prepared using a water extraction to remove the volatiles followed by a concentration process. It’s adaptogenic, antioxidant, and ginsenoside activity has been shown to promote strong erections in men experiencing erectile dysfunction. The minor ingredients of the placebo were glucose anhydrocrystalline (4.53%), green color from Gardenia jasminoides (1.36%), monascus color (0.72%), magnesium stearate (0.91%) and enzymatically modified stevia glucosyl stevia (0.05%). The TMGE group comprised 75 men; whereas the placebo group contained 68 men. The 143 patients selected were randomly divided into two groups, one receiving TMGE and the other receiving a placebo. Patients with severe neurological disorders such as spinal cord injury and multiple sclerosis, or with a history of radical prostatectomy, genital anomaly or drug abuse were excluded from the study. Informed consent was obtained from each subject, and the study was approved by the Institutional Review Board of Kyung Hee University, East-West Neo Medical Center. So, before taking any type of ginseng, talk to your healthcare provider. A 2021 review of research studies found support for using American ginseng to treat cancer-related fatigue. The connection between ginseng and improved immune system function has been well-chronicled over time. Generally, it’s advised to follow the product’s instructions or consult with a healthcare provider. From capsules to teas, ginseng offers various consumption methods tailored to individual preferences. Whether you are seeking an energy boost, cognitive enhancement, or immune support, ginseng stands as a versatile ally. Individuals with existing health conditions or on medications should seek guidance from their healthcare provider. A study led by Jonathon Lee Reay (Northumbria University, UK) published in Human Psychopharmacology shows that it improves aspects of working memory performance in young adults. Polysaccharides and oligopeptides in the American variety can potentially help to lower oxidative stress, fight fatigue, enhance physical activity, and boost energy. Other compounds include polyacetylenes such as panaxynol and panaxydol, polyphenolic compounds, arginine, and its derivatives, as well as acidic polysaccharides. Ginseng contains a compound called ginsenosides, which is responsible for its main medicinal benefits. Similar to its other counterparts, Ashwagandha is also used to boost fertility in men and improve the functioning of their reproductive system. Ginseng has been found to be highly effective in boosting sperm count in males. It helps to boost sexual performance and therefore aids in reproduction. Ginseng is highly effective in improving libido or sex drive in males. How Much Panax Ginseng Should I Take Per Day? With carefully selected ingredients, Nitrox Pro promotes firm, long-lasting, and intense erections quickly and without side effects. These are the effects observed in users over 55 years old in less than 7 minutes. The image above shows the effectiveness of the 6-month treatment, based on research conducted on more than 1,750 volunteers aged 53 to 79 at Stanford University. The data on fenugreek’s utility in improving sexual function are sparse and sometimes conflicting, and no studies have been conducted specifically on its application in ED treatment. Only two RCTs have studied the use of fenugreek in treatment of sexual dysfunctions. Until the body of literature on saw palmetto expands, physicians should counsel patients that further work is required to assess its mechanism of action as well as the ingredient’s influence on sexual health and erectile function. Thus far, limited evidence exists that zinc supplementation increases testosterone levels or overall sexual function in men with adequate zinc intake. Thus, further studies are needed to more definitively determine the effects of muira puama alone on erectile function. Specifically, Performer 8 uses KSM-66, a branded form of ashwagandha that’s a high-quality, standardized extract.Moreover, Ayurvedic and other alternative medicines around the world have always used herbs to help improve symptoms related to ED.You should consult with a healthcare professional before starting any diet, exercise or supplementation program, before taking any medication, or if you have or suspect you might have a health problem.Individual responses depend on baseline health, age, and adherence to dosing recommendations.Traditional Chinese medicine (TCM), including acupuncture and Chinese herbs, is used as an alternative therapy to increase the curative effect for erectile dysfunction (ED).By enhancing stamina, ginseng can enable men to engage in physical activities more effectively, leading to improved performance both in and out of the bedroom.None of the RCTs reported the concealment of treatment allocation.It is now believed that the neurophysiological effects of acupuncture result from the central nervous system activation as well as neurotransmitters modulation (6).Administration of red ginseng extract increased coronary flow in individuals with cardiac ischemia . By supporting the adrenal glands and balancing cortisol levels, Ginseng improves mental clarity and physical stamina, helping men perform better in both the gym and the bedroom. It helps stimulate the nitric oxide pathways in the body, which improves blood flow to the penis, supporting stronger, longer-lasting erections. Flow chart of the study search Flow chart of the study… The mechanism of action of RG in MRH may be related to oxidative stress, regulation of sex hormones and spermatogenesis-related proteins, and anti-inflammation. Ginseng is generally a safe and effective natural remedy that can provide a wide range of benefits for men. Additionally, ginseng has been linked to increased muscle mass and strength, making it a popular supplement among athletes and bodybuilders. Although product recommendations are only our opinions, this research-backed page has been fact-checked and reviewed by a certified nutritionalist or health specialist. Prolonged use of the herb, however, is known to cause a variety of mild side-effects. The short-term use of ginseng at standard recommended doses does not appear to have a significant side-effect profile, and is safe for consumption in most people. It has been recommended to reduce both physiological and emotional stresses and regular ingestion has been shown to improve both mental and physical performance. Unlike some of the more aggressive Yang tonics, Goji berries have traditionally been used in TCM to nourish both Yin and Yang energies, making them an excellent balancing herb for male vitality formulations. Its inclusion in Cool Man™ alongside traditional TCM herbs like Epimedium and Cynomorium creates a comprehensive approach to male vitality that bridges ancient wisdom with modern botanical research. In the Cool Man™ formulation, Morinda officinalis works synergistically with other herbs to create a balanced approach to male vitality that addresses both physical and mental aspects of wellbeing. Morinda officinalis root, known as "Ba Ji Tian" in Chinese medicine, is another powerful Yang tonic included in Cool Man™. This variety contains a different profile of ginsenosides that more aggressively stimulate energy production, circulation, and warming functions in the body. GBE was prepared using the pulp and rinds from fresh P. ginseng berries. After collecting blood, the testis were dissected, dipped them in nitrogen gas and stored them at -70℃ deep freezer immediately 19,20. Enzyme-linked immunosorbent assay (ELISA) for detecting testosterone, TM3 cell supernatants were freezing before the experiment. That depends on the quality of the ginseng, an individuals’ level of healthy gut bacteria, and the quantity of compounds in the ginseng that you start with. The HRG80 ginseng that we feature in our red ginseng supplements is hydroponically grown. Additionally, ginseng can improve libido and reduce symptoms of sexual fatigue. Further, the sperm kinematics parameters of motility and progressiveness were significantly affected in HC group, which showed a similar tendency to earlier reported studies .Various active components, including saponins, polysaccharides, phenols, gomisin, acidic peptides, and other various carbohydrates, have been identified in ginseng 7,8.We presented an adapted PRISMA flow diagram showing the process of study selection (Liberati 2009).Therefore, ginseng can be used as an alternative treatment for ED .We included nine studies with 587 men with mild to moderate erectile dysfunction, aged from 20 to 70 years old.Testosterone supports libido, nitric‑oxide synthesis, and penile tissue health.This is the adaptogenic property of Panax ginseng which can help elevate your performance and reduce time to fatigue. Healthfieldtips Your path to optimal health starts here! Studies suggest its beneficial effects on sperm count, motility, and morphology, contributing to overall fertility in men. However, it’s essential to approach ginseng supplementation with caution, considering factors such as product quality, dosage, and lifestyle factors. Stress management techniques, such as mindfulness meditation, deep breathing exercises, and yoga, can also complement ginseng supplementation by reducing anxiety and promoting relaxation. Eating healthy doesn`t have to be time consuming.Here are my favorite ways to eat healthy with the least amount of prep time....🥦 Type PREP in the comments below and I will send you my Radical fertility Smoothie recipe and pre-pregnancy checklist. 🥦 Finally, nourishing ourselves with supportive foods is important for fertility and overall health. Thank goodness companies are responding to the need for “clean products” and creating effective and healthier alternatives. These compounds, known as ENDOCRINE DISRUPTORS, are causing hormonal imbalances which are negatively affecting our ability to ovulate.They also negatively affect EGG health and sperm count.♻️ These environmental factors include plastics (with BPA being one of the most commonly known), body care and hair care products, household cleaners, and even fragrance candles. Evidence has shown that the action of GS in ginseng enhances vascular endothelial abnormalities and possesses organ-protective action, especially in lungs, heart, and corpus cavernosum . In this review, we also observed that ginseng can also treat ED-related comorbidities such as hypertension, diabetes mellitus and hyperlipidemia. Ernst et al. (2011) also arrived at a similar conclusion as Khera and Goldstein (2011) where the experts concluded that Panax ginseng was the only herbal supplement test that received a cautiously positive conclusion without apparent safety issues . If you’re hoping that male enhancement products will increase the size of your penis, a penis extender would be a far better option. They’re actually mechanical devices designed to draw blood to the penis using vacuum pressure, resulting in an erection of sufficient hardness for penetrative sex. If confidence is part of a mental angle affecting your sexual performance, this might help. And there seems to be a direct link between obesity and poor sexual performance. For a thorough look at testosterone boosters, as well as testosterone replacement therapies, consult our comprehensive guide to the best testosterone boosters on the market. “Ginseng strengthens the soul, brightens the eyes, opens the heart, expels evil, benefits understanding and if taken for prolonged periods of time will invigorate the body and prolongs one's life.” It is likely that ginseng was originally used as a food amongst the farmers and field laborers; many ancient Chinese records show that it was used for medicinal purposes over 3000 years ago. Emperor Shen-Nung was the second of China's mythical emperors and is widely considered the father of Chinese medicine. We concentrate further on Emperor Shen-Nung and his role in medicine within ancient China. These mythical emperors brought to the people of this era, fire, architecture, principles of farming and agriculture, the calendar, and medicine. This was particularly seen in similarities with medicine and herbal remedies that have migrated to what is now modern-day Korea, Japan and Vietnam. Evidence of its existence has been extensively studied from age-old literature and archaeological studies. Widely considered the father of Chinese medicine, he has catalogued over 365 species of medicinal plants. Shen-Nung believed that ginseng's resemblance to the human form is proof of its rejuvenative and aphrodisiac properties. The reputation of ginseng as an aphrodisiac is based on the doctrine of signatures, since the adult root has a phallic shape. In my opinion, Ginseng is a herb that all guys should experiment with, to see how they react to the benefits examined above. The best thing about Ginseng is the fact that it’s so widely researched, and there’s also plenty of human studies too. B) Nitric oxide will greatly increase your overall blood flow. But there’s also some testosterone boosting abilities on this Korean root. You can easily understand why, if you take a look at those studies provided above. Although considerable advances have been made, the ideal treatment of ED has not been identified . However, the total number of RCTs included in the analysis, the total sample size and the methodological quality of the primary studies were too low to draw definitive conclusions. Always consult a healthcare professional before starting any supplement. Ginseng belongs to the genus Panax and includes Panax ginseng (P. ginseng, Korean ginseng), Panax quinquefolius (P. quinquefolius, American ginseng) and Panax notoginseng (P. notoginseng, Sanchi ginseng) (Jia 2019). When men were simply asked whether their erections improved (without using a specialized questionnaire), the results of this systematic review show that ginseng may improve the ability to have intercourse. These studies included 587 participants with mild to moderate difficulty in erection, aged 20 to 70 years old. We reviewed the literature to find out whether certain forms of ginseng, a popular root used in many countries, can help with erection problems. Medication and surgery can help with this problem, but studies also suggest that herbal supplements may help. You’ll see that Performer 8 outperforms the competition in most categories, with greater doses of ginseng and barrenwort than most competitors. We had to be very careful in evaluating male enhancement products, as so many contain ingredients without enough clinical research to recommend them in good conscience. Additionally, like all health-related content on this website, this guide was thoroughly vetted by one or more members of our Medical Review Board for accuracy. That said, male enhancement pills commonly target increased blood flow and relaxation of the corpus cavernosum. Different pills will have different effects at specific times throughout treatment. Like Semenax, VigRX subjected this male enhancement product to a relatively rigorous clinical study.28 The parameters were thorough, though the participant pool was small. Short‑term studies show no adverse impact on sperm parameters or endocrine balance when used within recommended dosages. Regular consumption of these foods, alongside a balanced diet, can complement supplement use and promote overall vascular health. Populations requiring caution comprise men with uncontrolled hypertension, arrhythmias, or those taking anticoagulants, as some botanicals (e.g., ginseng) possess mild antiplatelet activity. Common mild side effects include gastrointestinal discomfort (particularly with high‑dose L‑citrulline), transient headache, or vivid dreams linked to yohimbine. Preliminary data suggest synergistic improvements in penile blood flow measured by Doppler ultrasonography, though large‑scale trials are pending. There are various types of ginseng, including Korean red ginseng, American ginseng, and Siberian ginseng. However, the mechanism behind ginseng’s role in enhancing erections may not be directly related to boosting testosterone. Ginseng, a renowned herb in traditional medicine, particularly in Asian cultures, has been used for centuries for its myriad of therapeutic benefits. You should not use the information on this site for diagnosis or treatment of any health problem or for prescription of any medication or other treatment. In conclusion, the results of our systematic review and meta-analysis provide suggestive evidence for the effectiveness of red ginseng in treating ED. We were unable to perform sensitivity analysis because there were no studies with an overall low risk of bias. It may also have little to no effect on adverse events compared to placebo. All included studies were judged at high or unclear risk of bias. The remaining studies did not report their inclusion criteria with regard to comorbidities. None of the included studies reported quality of life as an outcome. The ginseng supplement from Solgar comes in a traditional capsule form, with each vegetarian cellulose capsule containing 250 mg of Korean ginseng extract, of which 8% is ginsenosides. The other ingredients are included purely to dissolve the ginseng extract, and they are vegetable glycerin and purified water. NuSci Panax Ginseng comes in powder form, packaged in a foil bag, with only one ingredient; ginseng extract. If you want to boost your immune system, improve your concentration levels, and feel more energized (especially in the bedroom), ginseng is a great place to start. The world of herbal remedies and natural supplements for male enhancement offers a range of potential options for those seeking to enhance their sexual wellness. This leads to an increase in blood flow into the penis and a decrease of blood flow out of the penis, resulting in an erection. In addition to being used as a medication, Panax ginseng is also frequently used to make various cosmetic products like makeup and soaps. Panax ginseng contains ginsenosides (a group of bioactive compounds found naturally in the roots, stems, and leaves of the ginseng plant). Counterbalancing Effects A meta-analysis of the efficacy of panax ginseng on menopausal women’s sexual function. Five studies evaluated the effects of ginseng on sexual function (Jang et al., 2008; Ghorbani and Mirghafourvand, 2019; Lee et al., 2021; Sha’ari et al., 2021; Lee et al., 2022). When compared with control treatments (mainly placebo), ginseng was beneficial for improving fatigue and physical function, sexual function, menopausal symptoms, metabolic indicators, inflammatory markers, unstable angina and respiratory diseases. Oral doses of powdered ginseng root sufficient to alter sexual behavior in male rats were as low as 10 mg/kg, and significant changes in libido were measured within one week of daily oral ginseng treatment . You are encouraged to verify any information with reliable sources and consult a qualified healthcare professional regarding any medical condition, treatment, or supplement use. According to a publication in the Medicines Journal, supplementation of Panax ginseng showed mild and temporary symptoms with no severe side effects. A research publication in Drug and Lactation Database notes that due to a lack of sufficient studies, Panax ginseng should not be used by children, expectant, and breastfeeding individuals. In ancient times we preferred to bring birth to sons because male progeny is a symbol of manpower for farming or hunting. It must be true that man has been seeking for an agent that can boost sexual ability ever since the prehistoric era when judged by historic literature. The authors found no trial evidence comparing ginseng to other agents with a more established role in treating ED, such as phosphodiesterase-5 inhibitors.15 Recently, a collaborative effort between scientists hailing from South Korea, Norway, and Australia has yielded a comprehensive review on the importance of P. ginseng and its potential impact on ED.15 The authors meticulously examined all the clinical trials conducted with ginseng, employing the most stringent methodological approach. These unique components interact with the body in complex ways, potentially influencing hormonal pathways that govern testosterone production. So, what makes Red Korean Ginseng a potential testosterone booster? Low levels can lead to fatigue, weight gain, and a waning sex drive.